BS6752

antibody from Bioworld Technology, Inc
Targeting: TPH1 TPH, TPRH
Provider product page for BS6752
Western blot
Immunohistochemistry

Antibody data

Product number
BS6752 - Provider product page
Provider
Bioworld Technology, Inc
Product name
TPH1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human TPH1.
Description
Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and tryptophan hydroxylase (TPH) comprise a small family of monooxygenases that use tetrahydropterine as a cofactor during the catabolism of aromatic L-amino acids. PAH, TH and TPH all contain catalytic domains with an amino-terminal regulatory domain and a short carboxy-terminal tetramerization domain. Each of these enzymes also contains a single ferrous iron atom, which is bound to two histidines and a glutamate and is likely to be involved in the formation of the hydroxylating intermediate. TPH is the first and rate-limiting step in the biosynthesis of serotonin in the central nervous system and melatonin in the pineal gland.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
TPH1 protein structure - BS6752 shown in red.