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- Antibody Data
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- References [6]
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- Validations
- Western blot [1]
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- Product number
- 60333-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- TMEM106B antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated TMEM106B antibody (Cat. #60333-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 5D1F8
- Vial size
- 20ul, 150ul
Submitted references TESC acts as a prognostic factor and promotes epithelial-mesenchymal transition progression in esophageal squamous carcinoma.
The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence.
C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes.
Accumulation of TMEM106B C-terminal fragments in neurodegenerative disease and aging.
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation.
Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Dong Y, Fan B, Li M, Zhang J, Xie S, Di S, Jia Q, Gong T
Pathology, research and practice 2024 Jan;253:154964
Pathology, research and practice 2024 Jan;253:154964
The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence.
Ayoubi R, Fotouhi M, Southern K, Bhajiawala R, Fanti R, Prinos P, McPherson PS, Laflamme C, NeuroSGC/YCharOS/EDDU collaborative group, ABIF Consortium
F1000Research 2023;12:308
F1000Research 2023;12:308
C-terminal TMEM106B fragments in human brain correlate with disease-associated TMEM106B haplotypes.
T Vicente C, Perneel J, Wynants S, Heeman B, Van den Broeck M, Baker M, Cheung S, Faura J, Mackenzie IRA, Rademakers R
Brain : a journal of neurology 2023 Oct 3;146(10):4055-4064
Brain : a journal of neurology 2023 Oct 3;146(10):4055-4064
Accumulation of TMEM106B C-terminal fragments in neurodegenerative disease and aging.
Perneel J, Neumann M, Heeman B, Cheung S, Van den Broeck M, Wynants S, Baker M, Vicente CT, Faura J, Rademakers R, Mackenzie IRA
Acta neuropathologica 2023 Mar;145(3):285-302
Acta neuropathologica 2023 Mar;145(3):285-302
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation.
Bauer CS, Webster CP, Shaw AC, Kok JR, Castelli LM, Lin YH, Smith EF, Illanes-Álvarez F, Higginbottom A, Shaw PJ, Azzouz M, Ferraiuolo L, Hautbergue GM, Grierson AJ, De Vos KJ
Frontiers in cellular neuroscience 2022;16:1061559
Frontiers in cellular neuroscience 2022;16:1061559
Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases.
Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson DW, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
Cell 2022 Apr 14;185(8):1346-1355.e15
Cell 2022 Apr 14;185(8):1346-1355.e15
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- U-251 cells were subjected to SDS PAGE followed by western blot with 60333-1-Ig( TMEM106B Antibody) at dilution of 1:1000
- Validation comment
- WB
