Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Immunohistochemistry [1]
- Other assay [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PA5-25050 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Tubulin beta-2C Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- This antibody is predicted to react with bovine, chicken, canine, hamster, mouse, porcine, rat and Xenopus based on sequence homology.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 400 µL
- Concentration
- 0.5 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Tubulin Beta 2C Chain (TBB2C), a Potential Marker of Ovarian Cancer, an Insight from Ovarian Cancer Proteome Profile.
Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer.
Noreen S, Akhtar S, Batool T, Gardner QA, Akhtar MW
ACS omega 2021 Apr 27;6(16):10506-10514
ACS omega 2021 Apr 27;6(16):10506-10514
Therapeutic efficacy of a novel βIII/βIV-tubulin inhibitor (VERU-111) in pancreatic cancer.
Kashyap VK, Wang Q, Setua S, Nagesh PKB, Chauhan N, Kumari S, Chowdhury P, Miller DD, Yallapu MM, Li W, Jaggi M, Hafeez BB, Chauhan SC
Journal of experimental & clinical cancer research : CR 2019 Jan 23;38(1):29
Journal of experimental & clinical cancer research : CR 2019 Jan 23;38(1):29
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of Tubulin beta-2C in formalin fixed and paraffin embedded human brain tissue. Samples were incubated with Tubulin beta-2C polyclonal antibody (Product # PA5-25050) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 3 Validation analysis of the candidate proteins. Immunoblots of TBB2C and VIM. (A) Relative expression of TBB2C in different OC stages compared to benign controls and healthy subjects (ns, non significant; * p -value, 0.01; *** p -value, 0.0004; **** p -value < 0.0001). (B) ROC curve displaying TBB2C sensitivity to distinguish OC from benign controls and healthy subjects, and benign controls from healthy subjects (C).
