MA1-35020

antibody from Invitrogen Antibodies

Targeting: CGB3 CGB

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

MA1-35020

Provider

Invitrogen Antibodies

Product name

hCG beta Monoclonal Antibody (5H4-E2)

Antibody type

Monoclonal

Antigen

Other

Description

5H4-E2 reacts with hCG beta chain, which is specific for hCG. The alpha chain is identical among hCG, TSH, FSH and LH. While hCG is secreted in large quantities by normal trophoblasts, it is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. Besides trophoblastic tumors e.g. choriocarcinoma, large cell carcinoma, adenocarcinoma and squamous cell carcinoma of the lung are also positive in 90%, 60% and 20% of cases respectively. In hCG producing tumors, including also certain testicular and embryonic carcinomas, the beta chain is produced in higher quantities than the alpha or dimeric chains. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

5H4-E2

Vial size

100 µg

Concentration

0.1 mg/mL

Storage

4° C