CGB3

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq, Jul 2008]

Description

Chorionic gonadotropin subunit beta 3

Tissue specificity

Tissue enriched (placenta)

Subcell location

Cytosol

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins

Chromosome

19 (49022869 - 49024333)

Ensembl ID

ENSG00000104827  (ver. 103.38)

Orthologs

-

UniProt

P0DN86

neXtProt

NX_P0DN86

Human splice variants

Protein structure