11615-1-AP

antibody from Proteintech Group

Targeting: CGB3 CGB

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

11615-1-AP

Provider

Proteintech Group

Product name

hCG Beta antibody

Antibody type

Polyclonal

Description

KD/KO validated hCG Beta antibody (Cat. #11615-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

HIF-2α / HILPDA promotes ferroptosis sensitivity in placenta trophoblast cells of early-onset preeclampsia.

Wang Q, Yang N, Chen H, Ding B, Dou C, Wang X, Pan X, Wang X, Li X
Placenta 2026 Feb;174:126-137

---

LK-1: an investigational therapy targeting hCG-β in metastatic breast, bladder, ovarian, and cervical cancers.

Kinion JH, McAllister MB, Summerton JE, Dolan BP
Scientific reports 2026 Feb 20;16(1)

---

Amyloid-β fibrils accumulated in preeclamptic placentas suppress cytotrophoblast syncytialization.

Nishioka K, Ikezaki M, Iwahashi N, Arakawa M, Fukushima M, Mori N, Mizoguchi M, Horiuchi-Tanizaki Y, Fujino M, Tomiyama T, Ihara Y, Uchimura K, Ino K, Nishitsuji K
Life science alliance 2026 Apr;9(4)

---

Transplacental transfer of metformin and interaction of metformin with the uptake transporters of placental trophoblast cells.

Gu X, Cai Y, Zheng C, Li K, Zhu S, Zhang S, Wang Z, Xiang J, Cheng Z, Ai X, Yang C
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2025 Sep 1;212:107161

---

Influenza a(H1N1) virus infection impairs syncytiotrophoblast functions by promoting ferroptosis through the TNF-α/ISG15/EGR1 axis.

Zhao Y, Wang Y, Huang K, Wang F, Wang Y
Virology journal 2025 Nov 17;22(1):379

---

Role of ferroptosis-related GPX4 signaling in the fusion of human trophoblast cells.

Yoshida K, Kusama K, Sato S, Kawaguchi Y, Horiuchi A, Yoshie M, Tamura K
Scientific reports 2025 Nov 11;15(1):39515

---

Liquid crystal monomers induce placental development and progesterone release dysregulation through transplacental transportation.

Zhang S, Cheng Z, Zhang T, Ding Y, Zhu H, Wang L, Sun H
Nature communications 2025 Jan 31;16(1):1204

---

Control of Golgi- V-ATPase through Sac1-dependent co-regulation of PI(4)P and cholesterol.

Zhou X, van der Stoel MM, Kaptan S, Li H, Li S, Hölttä M, Vihinen H, Jokitalo E, Thiele C, Pietiläinen O, Morioka S, Sasaki J, Sasaki T, Vattulainen I, Ikonen E
Nature communications 2025 Aug 21;16(1):7808

---

Identification of Fatty Acid Metabolism-Related Subtypes in Gastric Cancer Aided by Machine Learning.

Hou M, Chen J, Yang L, Qin L, Liu J, Zhao H, Guo Y, Yu QQ, Zhang Q
Cancer management and research 2024;16:1463-1473

---

Hypermethylation and low expression of FOXM1 predisposes women to unexplained recurrent miscarriage by impairing trophoblast stem cell proliferation.

Jiang Y, Zhu H, Wang T, Tong H, Liu J, Yang Y, Zhou X, Liu X
Cellular signalling 2024 Sep;121:111259

---

STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57(Kip2).

Li X, Shao LZ, Li ZH, Wang YH, Cai QY, Wang S, Chen H, Sheng J, Luo X, Chen XM, Wang YX, Ding YB, Liu TH
Journal of translational medicine 2024 Sep 20;22(1):852

---

Targeting Mitochondrial Oxidative Stress to Protect Against Preterm Birth and Fetal Brain Injury via Nrf2 Induction.

Chen C, Zhu S, Fu T, Chen Y, Bai L, Chen D
Antioxidants & redox signaling 2024 Oct;41(10-12):597-615

---

Influenza A virus infection disrupts the function of syncytiotrophoblast cells and contributes to adverse pregnancy outcomes.

Wang J, Liu W, Zhuang Y, Yang J, Zhao Y, Hong A, Du J, Kong H, Wang J, Jiang Y, Wang Y
Journal of medical virology 2024 Jun;96(6):e29687

---

Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus.

Ning J, Yan J, Wang S, Cui Z, Xue Y, Juan J, Yang H
iScience 2024 Jun 21;27(6):109900

---

Epigenetic drug screening for trophoblast syncytialization reveals a novel role for MLL1 in regulating fetoplacental growth.

Wu J, Qin C, Tian F, Liu X, Hu J, Wu F, Chen C, Lin Y
BMC medicine 2024 Feb 5;22(1):57

---

Activation of G protein-coupled estrogen receptor stimulates placental human chorionic gonadotropin expression through PKA-CREB signaling.

Yang S, Jia Y, Wu Z, Fu B, Zhou S, Pires LV, Cheng JC, Fang L
Molecular and cellular endocrinology 2023 Nov 1;577:112033

---

GDF-11 downregulates placental human chorionic gonadotropin expression by activating SMAD2/3 signaling.

Wu Z, Zhang L, Jia Y, Bi B, Fang L, Cheng JC
Cell communication and signaling : CCS 2023 Jul 21;21(1):179

---

Calnexin Is Involved in Forskolin-Induced Syncytialization in Cytotrophoblast Model BeWo Cells.

Matsukawa H, Ikezaki M, Nishioka K, Iwahashi N, Fujimoto M, Nishitsuji K, Ihara Y, Ino K
Biomolecules 2022 Jul 28;12(8)

---

The roles of ADAMDEC1 in trophoblast differentiation during normal pregnancy and preeclampsia.

Li ZH, Li X, Li FF, Wu ZH, Xie YL, Zhang S, Chen XM, Wang YX, Ding YB, Liu TH
Molecular human reproduction 2022 Apr 29;28(5)

---

Amphiregulin stimulates human chorionic gonadotropin expression by inducing ERK1/2-mediated ID3 expression in trophoblast cells.

Fang L, Wang S, Han X, Gao Y, Li Y, Cheng JC, Sun YP
Placenta 2021 Sep 1;112:73-80

---

Molecular mechanisms underlying altered neurobehavioural development of female offspring of mothers with polycystic ovary syndrome: FOS-mediated regulation of neurotrophins in placenta.

Wang F, Xie N, Zhou J, Dai M, Zhang Q, Hardiman PJ, Qu F
EBioMedicine 2020 Oct;60:102993

---

Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt Signaling Pathway.

Li M, Cheng W, Nie T, Lai H, Hu X, Luo J, Li F, Li H
Biological trace element research 2018 Jul;184(1):47-59