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LearnMAB665
antibody from Novus Biologicals
Targeting: FGFR2
BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25
Western blot
Blocking/NeutralizingAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
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- Product number
- MAB665 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal FGFR2 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Reacts with multiple isoforms of human FGF R2 although it shows a marked preference for human FGF R2 (IIIb) isoforms in some assays as described below. In direct ELISAs, displays a three-fold preference for FGF R2 (IIIb) isoforms over (IIIc) isoforms. Shows approximately 50% cross-reactivity with recombinant mouse (rm) FGF R2 isoforms and no cross-reactivity with any isoforms of recombinant human (rh) FGF R1 or rhFGF R3. In Western blots, shows approximately 25% cross-reactivity with rhFGF R2 (IIIc) isoforms, 100% cross-reactivity with all isoforms of rmFGF R2 and no cross-reactivity with any isoforms of rhFGF RI, rhFGF R3, or rhFGF R4. Neutralizes the bioactivity of rhFGF R2 (IIIb) isoforms.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Translocation of fibroblast growth factor-10 and its receptor into nuclei of human urothelial cells.
Kosman J, Carmean N, Leaf EM, Dyamenahalli K, Bassuk JA
Journal of cellular biochemistry 2007 Oct 15;102(3):769-85
Journal of cellular biochemistry 2007 Oct 15;102(3):769-85
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- FGF R2a Inhibition of FGF acidic-dependent Cell Proliferation and Neutralization by Human FGF R2 Antibody. FGF R2a Inhibition of FGF acidic-dependent Cell Proliferation and Neutralization by Human FGF R2 Antibody.
