Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 25167-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ALDH1A3 antibody
- Antibody type
- Polyclonal
- Description
- ALDH1A3 antibody (Cat. #25167-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A human embryonic limb cell atlas resolved in space and time.
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition.
Modification of lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression.
EGFRvIII Promotes the Proneural-Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis.
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
Autotaxin signaling facilitates β cell dedifferentiation and dysfunction induced by Sirtuin 3 deficiency.
MiR-195 promotes pancreatic β-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.
RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression.
Flavonoid 4,4'-dimethoxychalcone suppresses cell proliferation via dehydrogenase inhibition and oxidative stress aggravation.
Lipid-derived electrophiles mediate the effects of chemotherapeutic topoisomerase I poisons.
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.
Inhibition of breast cancer growth via miR-7 suppressing ALDH1A3 activity concomitant with decreasing breast cancer stem cell subpopulation.
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.
Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders.
Zhang B, He P, Lawrence JEG, Wang S, Tuck E, Williams BA, Roberts K, Kleshchevnikov V, Mamanova L, Bolt L, Polanski K, Li T, Elmentaite R, Fasouli ES, Prete M, He X, Yayon N, Fu Y, Yang H, Liang C, Zhang H, Blain R, Chedotal A, FitzPatrick DR, Firth H, Dean A, Bayraktar OA, Marioni JC, Barker RA, Storer MA, Wold BJ, Zhang H, Teichmann SA
Nature 2024 Nov;635(8039):668-678
Nature 2024 Nov;635(8039):668-678
Gut microbial metabolite facilitates colorectal cancer development via ferroptosis inhibition.
Cui W, Guo M, Liu D, Xiao P, Yang C, Huang H, Liang C, Yang Y, Fu X, Zhang Y, Liu J, Shi S, Cong J, Han Z, Xu Y, Du L, Yin C, Zhang Y, Sun J, Gu W, Chai R, Zhu S, Chu B
Nature cell biology 2024 Jan;26(1):124-137
Nature cell biology 2024 Jan;26(1):124-137
Modification of lysine-260 2-hydroxyisobutyrylation destabilizes ALDH1A1 expression to regulate bladder cancer progression.
Zhang Z, Wang Y, Liang Z, Meng Z, Zhang X, Ma G, Chen Y, Zhang M, Su Y, Li Z, Liang Y, Niu H
iScience 2023 Nov 17;26(11):108142
iScience 2023 Nov 17;26(11):108142
EGFRvIII Promotes the Proneural-Mesenchymal Transition of Glioblastoma Multiforme and Reduces Its Sensitivity to Temozolomide by Regulating the NF-κB/ALDH1A3 Axis.
Shi ZF, Li GZ, Zhai Y, Pan CQ, Wang D, Yu MC, Liu C, Zhang W, Yu XG
Genes 2023 Mar 4;14(3)
Genes 2023 Mar 4;14(3)
ATRA-mediated-crosstalk between stellate cells and Kupffer cells inhibits autophagy and promotes NLRP3 activation in acute liver injury.
Yu Z, Xie X, Su X, Lv H, Song S, Liu C, You Y, Tian M, Zhu L, Wang L, Qi J, Zhu Q
Cellular signalling 2022 May;93:110304
Cellular signalling 2022 May;93:110304
Autotaxin signaling facilitates β cell dedifferentiation and dysfunction induced by Sirtuin 3 deficiency.
Cao H, Chung ACK, Ming X, Mao D, Lee HM, Cao X, Rutter GA, Chan JCN, Tian XY, Kong APS
Molecular metabolism 2022 Jun;60:101493
Molecular metabolism 2022 Jun;60:101493
MiR-195 promotes pancreatic β-cell dedifferentiation by targeting Mfn2 and impairing Pi3k/Akt signaling in type 2 diabetes.
Xu Y, Tang Z, Dai H, Hou J, Li F, Tang Z, Zhang D
Obesity (Silver Spring, Md.) 2022 Feb;30(2):447-459
Obesity (Silver Spring, Md.) 2022 Feb;30(2):447-459
RNF8 up-regulates AR/ARV7 action to contribute to advanced prostate cancer progression.
Zhou T, Wang S, Song X, Liu W, Dong F, Huo Y, Zou R, Wang C, Zhang S, Liu W, Sun G, Lin L, Zeng K, Dong X, Guo Q, Yi F, Wang Z, Li X, Jiang B, Cao L, Zhao Y
Cell death & disease 2022 Apr 15;13(4):352
Cell death & disease 2022 Apr 15;13(4):352
Flavonoid 4,4'-dimethoxychalcone suppresses cell proliferation via dehydrogenase inhibition and oxidative stress aggravation.
Yang C, Zhu S, Chen Y, Liu Z, Zhang W, Zhao C, Luo C, Deng H
Free radical biology & medicine 2021 Nov 1;175:206-215
Free radical biology & medicine 2021 Nov 1;175:206-215
Lipid-derived electrophiles mediate the effects of chemotherapeutic topoisomerase I poisons.
Flor A, Wolfgeher D, Li J, Hanakahi LA, Kron SJ
Cell chemical biology 2021 Jun 17;28(6):776-787.e8
Cell chemical biology 2021 Jun 17;28(6):776-787.e8
Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells.
Zhang J, Yang S, Guan H, Zhou J, Gao Y
Journal of cellular and molecular medicine 2021 Feb;25(3):1688-1699
Journal of cellular and molecular medicine 2021 Feb;25(3):1688-1699
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α.
Le Thomas A, Ferri E, Marsters S, Harnoss JM, Lawrence DA, Zuazo-Gaztelu I, Modrusan Z, Chan S, Solon M, Chalouni C, Li W, Koeppen H, Rudolph J, Wang W, Wu TD, Walter P, Ashkenazi A
Nature communications 2021 Dec 15;12(1):7310
Nature communications 2021 Dec 15;12(1):7310
Inhibition of breast cancer growth via miR-7 suppressing ALDH1A3 activity concomitant with decreasing breast cancer stem cell subpopulation.
Pan M, Li M, You C, Zhao F, Guo M, Xu H, Li L, Wang L, Dou J
Journal of cellular physiology 2020 Feb;235(2):1405-1416
Journal of cellular physiology 2020 Feb;235(2):1405-1416
Cultivation of Hair Matrix Cells from Cashmere Goat Skins and Exemplified Applications.
Ma S, Wang L, Zong B, Wang Y, Wang X, Shi Y, Yang Y, Chen Y
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Animals : an open access journal from MDPI 2020 Aug 12;10(8)
Glyoxalase 1 gene is highly expressed in basal-like human breast cancers and contributes to survival of ALDH1-positive breast cancer stem cells.
Tamori S, Nozaki Y, Motomura H, Nakane H, Katayama R, Onaga C, Kikuchi E, Shimada N, Suzuki Y, Noike M, Hara Y, Sato K, Sato T, Yamamoto K, Hanawa T, Imai M, Abe R, Yoshimori A, Takasawa R, Tanuma SI, Akimoto K
Oncotarget 2018 Nov 23;9(92):36515-36529
Oncotarget 2018 Nov 23;9(92):36515-36529
Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders.
Xu X, Li C, Gao X, Xia K, Guo H, Li Y, Hao Z, Zhang L, Gao D, Xu C, Xu H, Xiong ZQ, Qiu Z, Mei L, Xie X, Ruan K, Hu R
Cell research 2018 Jan;28(1):48-68
Cell research 2018 Jan;28(1):48-68
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ALDH1A3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ALDH1A3. This antibody recognizes human, mouse antigen. The ALDH1A3 antibody has been validated for the following applications: ELISA, WB analysis.