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- Antibody Data
- Antigen structure
- References [12]
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- Western blot [1]
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- Product number
- 21565-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21565-1-AP, RRID:AB_10734587
- Product name
- ATP8A1 antibody
- Antibody type
- Polyclonal
- Description
- ATP8A1 antibody (Cat. #21565-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of potential molecular targets for the treatment of cluster 1 human pheochromocytoma and paraganglioma via comprehensive proteomic characterization.
Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1.
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation.
Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer's disease.
AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells.
2-Aminoethoxydiphenylborate (2-APB) inhibits release of phosphatidylserine-exposing extracellular vesicles from platelets.
Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets.
Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells.
Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues.
Proteomic Analysis of the Rat Canalicular Membrane Reveals Expression of a Complex System of P4-ATPases in Liver.
MiR-140-3p suppressed cell growth and invasion by downregulating the expression of ATP8A1 in non-small cell lung cancer.
Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase.
Vit O, Talacko P, Musil Z, Hartmann I, Pacak K, Petrak J
Clinical proteomics 2023 Sep 25;20(1):39
Clinical proteomics 2023 Sep 25;20(1):39
Adaptor protein AP-3 produces synaptic vesicles that release at high frequency by recruiting phospholipid flippase ATP8A1.
Xu H, Oses-Prieto JA, Khvotchev M, Jain S, Liang J, Burlingame A, Edwards RH
Nature neuroscience 2023 Oct;26(10):1685-1700
Nature neuroscience 2023 Oct;26(10):1685-1700
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation.
Inoue C, Mukai K, Matsudaira T, Nakayama J, Kono N, Aoki J, Arai H, Uchida Y, Taguchi T
Scientific reports 2023 Nov 13;13(1):19740
Scientific reports 2023 Nov 13;13(1):19740
Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer's disease.
Kaneshiro N, Komai M, Imaoka R, Ikeda A, Kamikubo Y, Saito T, Saido TC, Tomita T, Hashimoto T, Iwatsubo T, Sakurai T, Uehara T, Takasugi N
iScience 2022 Mar 18;25(3):103869
iScience 2022 Mar 18;25(3):103869
AP-3-dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells.
Kook S, Wang P, Meng S, Jetter CS, Sucre JMS, Benjamin JT, Gokey JJ, Hanby HA, Jaume A, Goetzl L, Marks MS, Guttentag SH
Proceedings of the National Academy of Sciences of the United States of America 2021 May 18;118(20)
Proceedings of the National Academy of Sciences of the United States of America 2021 May 18;118(20)
2-Aminoethoxydiphenylborate (2-APB) inhibits release of phosphatidylserine-exposing extracellular vesicles from platelets.
Wei H, Davies JE, Harper MT
Cell death discovery 2020;6:10
Cell death discovery 2020;6:10
Calpain cleaves phospholipid flippase ATP8A1 during apoptosis in platelets.
Jing W, Yabas M, Bröer A, Coupland L, Gardiner EE, Enders A, Bröer S
Blood advances 2019 Feb 12;3(3):219-229
Blood advances 2019 Feb 12;3(3):219-229
Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells.
Liou AY, Molday LL, Wang J, Andersen JP, Molday RS
The Journal of biological chemistry 2019 Apr 26;294(17):6809-6821
The Journal of biological chemistry 2019 Apr 26;294(17):6809-6821
Proteomic Analysis and Functional Characterization of P4-ATPase Phospholipid Flippases from Murine Tissues.
Wang J, Molday LL, Hii T, Coleman JA, Wen T, Andersen JP, Molday RS
Scientific reports 2018 Jul 17;8(1):10795
Scientific reports 2018 Jul 17;8(1):10795
Proteomic Analysis of the Rat Canalicular Membrane Reveals Expression of a Complex System of P4-ATPases in Liver.
Chaubey PM, Hofstetter L, Roschitzki B, Stieger B
PloS one 2016;11(6):e0158033
PloS one 2016;11(6):e0158033
MiR-140-3p suppressed cell growth and invasion by downregulating the expression of ATP8A1 in non-small cell lung cancer.
Dong W, Yao C, Teng X, Chai J, Yang X, Li B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2973-85
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2973-85
Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase.
Lee S, Uchida Y, Wang J, Matsudaira T, Nakagawa T, Kishimoto T, Mukai K, Inaba T, Kobayashi T, Molday RS, Taguchi T, Arai H
The EMBO journal 2015 Mar 4;34(5):669-88
The EMBO journal 2015 Mar 4;34(5):669-88
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATP8A1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ATP8A1. This antibody recognizes human,mouse,rat antigen. The ATP8A1 antibody has been validated for the following applications: ELISA, WB analysis.
