Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 19011-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19011-1-AP, RRID:AB_2115817
- Product name
- GUCY1B3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GUCY1B3 antibody (Cat. #19011-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Specific dilation pattern in placental circulation and the NO/sGC role in preeclampsia placental vessels.
Aortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO.
Upregulation of Connexin 40 Mediated by Nitric Oxide Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage via the Nitric Oxide-Cyclic Guanosine Monophosphate-Protein Kinase G Pathway.
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway.
Cavin-3 (PRKCDBP) deficiency reduces the density of caveolae in smooth muscle.
Tang J, Zhang Y, Zhang Z, Tao J, Wu J, Zheng Q, Xu T, Li N, Xu Z
Frontiers in endocrinology 2023;14:1182636
Frontiers in endocrinology 2023;14:1182636
Aortic disease in Marfan syndrome is caused by overactivation of sGC-PRKG signaling by NO.
de la Fuente-Alonso A, Toral M, Alfayate A, Ruiz-Rodríguez MJ, Bonzón-Kulichenko E, Teixido-Tura G, Martínez-Martínez S, Méndez-Olivares MJ, López-Maderuelo D, González-Valdés I, Garcia-Izquierdo E, Mingo S, Martín CE, Muiño-Mosquera L, De Backer J, Nistal JF, Forteza A, Evangelista A, Vázquez J, Campanero MR, Redondo JM
Nature communications 2021 May 11;12(1):2628
Nature communications 2021 May 11;12(1):2628
Upregulation of Connexin 40 Mediated by Nitric Oxide Attenuates Cerebral Vasospasm After Subarachnoid Hemorrhage via the Nitric Oxide-Cyclic Guanosine Monophosphate-Protein Kinase G Pathway.
Lan SH, Lai WT, Zheng SY, Yang L, Fang LC, Zhou L, Tang B, Duan J, Hong T
World neurosurgery 2020 Apr;136:e476-e486
World neurosurgery 2020 Apr;136:e476-e486
Empagliflozin prevents cardiomyopathy via sGC-cGMP-PKG pathway in type 2 diabetes mice.
Xue M, Li T, Wang Y, Chang Y, Cheng Y, Lu Y, Liu X, Xu L, Li X, Yu X, Sun B, Chen L
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Clinical science (London, England : 1979) 2019 Aug 15;133(15):1705-1720
Hypertension reduces soluble guanylyl cyclase expression in the mouse aorta via the Notch signaling pathway.
Rippe C, Zhu B, Krawczyk KK, Bavel EV, Albinsson S, Sjölund J, Bakker ENTP, Swärd K
Scientific reports 2017 May 2;7(1):1334
Scientific reports 2017 May 2;7(1):1334
Cavin-3 (PRKCDBP) deficiency reduces the density of caveolae in smooth muscle.
Zhu B, Swärd K, Ekman M, Uvelius B, Rippe C
Cell and tissue research 2017 Jun;368(3):591-602
Cell and tissue research 2017 Jun;368(3):591-602
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 19011-1-AP(GUCY1B3 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using GUCY1B3 antibody 19011-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line