Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14915-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14915-1-AP, RRID:AB_10896496
- Product name
- TOB1 antibody
- Antibody type
- Polyclonal
- Description
- TOB1 antibody (Cat. #14915-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways.
Effect of mir-92a-3p on hydroquinone induced changes in human lymphoblastoid cell cycle and apoptosis.
Preferential translation of p53 target genes.
TOB1 attenuates IRF3-directed antiviral responses by recruiting HDAC8 to specifically suppress IFN-β expression.
Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.
NEDD4 triggers FOXA1 ubiquitination and promotes colon cancer progression under microRNA-340-5p suppression and ATF1 upregulation.
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Phosphorylation of TOB1 at T172 and S320 is critical for gastric cancer proliferation and progression.
Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network.
Peng G, Liu T, Qi X, Wang Y, Ren J, Peng J, Du X, Hu S, Wu S, Zhao Y, Li D, Zheng H
PLoS pathogens 2024 Mar;20(3):e1012104
PLoS pathogens 2024 Mar;20(3):e1012104
Effect of mir-92a-3p on hydroquinone induced changes in human lymphoblastoid cell cycle and apoptosis.
Xuan M, Wu Y, Wang H, Ye Z, Wu H, Chen Y, Yang H, Tang H
Environmental toxicology 2023 Jun;38(6):1420-1430
Environmental toxicology 2023 Jun;38(6):1420-1430
Preferential translation of p53 target genes.
Hisaoka M, Schott J, Bortecen T, Lindner D, Krijgsveld J, Stoecklin G
RNA biology 2022;19(1):437-452
RNA biology 2022;19(1):437-452
TOB1 attenuates IRF3-directed antiviral responses by recruiting HDAC8 to specifically suppress IFN-β expression.
Yu Z, Wang L, Zhao J, Song H, Zhao C, Zhao W, Jia M
Communications biology 2022 Sep 9;5(1):943
Communications biology 2022 Sep 9;5(1):943
Control of immediate early gene expression by CPEB4-repressor complex-mediated mRNA degradation.
Poetz F, Lebedeva S, Schott J, Lindner D, Ohler U, Stoecklin G
Genome biology 2022 Sep 12;23(1):193
Genome biology 2022 Sep 12;23(1):193
NEDD4 triggers FOXA1 ubiquitination and promotes colon cancer progression under microRNA-340-5p suppression and ATF1 upregulation.
Yue M, Yun Z, Li S, Yan G, Kang Z
RNA biology 2021 Nov;18(11):1981-1995
RNA biology 2021 Nov;18(11):1981-1995
TOB1 suppresses proliferation in K-Ras wild-type pancreatic cancer.
Bai Y, Qiao L, Xie N, Li Y, Nie Y, Pan Y, Shi Y, Wang J, Liu N
Cancer medicine 2020 Feb;9(4):1503-1514
Cancer medicine 2020 Feb;9(4):1503-1514
Phosphorylation of TOB1 at T172 and S320 is critical for gastric cancer proliferation and progression.
Wang D, Song H, Zhao T, Wang M, Wang Y, Yu L, Wang P, Yu J
American journal of translational research 2019;11(8):5227-5239
American journal of translational research 2019;11(8):5227-5239
Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network.
Zhu J, Wang S, Zhang W, Qiu J, Shan Y, Yang D, Shen B
Oncotarget 2015 Dec 22;6(41):43819-30
Oncotarget 2015 Dec 22;6(41):43819-30
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 14915-1-AP(TOB1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach using 14915-1-AP(TOB1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TOB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TOB1. This antibody recognizes human,mouse,rat antigen. The TOB1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.