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Learn17430-1-AP
antibody from Proteintech Group
Targeting: MAGT1
DKFZp564K142, IAP, MRX95, OST3B, SLC58A1
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 17430-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17430-1-AP, RRID:AB_2138982
- Product name
- MAGT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated MAGT1 antibody (Cat. #17430-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references XMEN disease caused by the novel MAGT1 p.(Trp136*) mutation may present with neuropsychiatric symptoms.
Magnetic Field Boosts the Transmembrane Transport Efficiency of Magnesium Ions from PLLA Bone Scaffold.
MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation.
Epigenetic activation of the TUSC3 gene as a potential therapy for XMEN disease.
MAGT1 messenger RNA-corrected autologous T and natural killer cells for potential cell therapy in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia disease.
Mutations in MAGT1 lead to a glycosylation disorder with a variable phenotype.
MicroRNA-148b regulates tumor growth of non-small cell lung cancer through targeting MAPK/JNK pathway.
A Magnesium-Enriched 3D Culture System that Mimics the Bone Development Microenvironment for Vascularized Bone Regeneration.
MagT1 regulated the odontogenic differentiation of BMMSCs induced byTGC-CM via ERK signaling pathway.
Comprehensive Interactome Analysis Reveals that STT3B Is Required for N-Glycosylation of Lassa Virus Glycoprotein.
Construction of green fluorescence protein mutant to monitor STT3B-dependent N-glycosylation.
Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex.
The different expression of TRPM7 and MagT1 impacts on the proliferation of colon carcinoma cells sensitive or resistant to doxorubicin.
Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens.
Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation.
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
Second messenger role for Mg2+ revealed by human T-cell immunodeficiency.
Villenheimo H, Glumoff V, Räsänen S, Jartti A, Rusanen H, Åström P, Kuismin O, Hautala T
Journal of neuroimmunology 2024 Aug 15;393:578386
Journal of neuroimmunology 2024 Aug 15;393:578386
Magnetic Field Boosts the Transmembrane Transport Efficiency of Magnesium Ions from PLLA Bone Scaffold.
Yan Z, Sun T, Tan W, Wang Z, Yan J, Miao J, Wu X, Feng P, Deng Y
Small (Weinheim an der Bergstrasse, Germany) 2023 Oct;19(40):e2301426
Small (Weinheim an der Bergstrasse, Germany) 2023 Oct;19(40):e2301426
MAGT1 deficiency in XMEN disease is associated with severe platelet dysfunction and impaired platelet glycoprotein N-glycosylation.
Kauskot A, Mallebranche C, Bruneel A, Fenaille F, Solarz J, Viellard T, Feng M, Repérant C, Bordet JC, Cholet S, Denis CV, McCluskey G, Latour S, Martin E, Pellier I, Lasne D, Borgel D, Kracker S, Ziegler A, Tuffigo M, Fournier B, Miot C, Adam F
Journal of thrombosis and haemostasis : JTH 2023 Nov;21(11):3268-3278
Journal of thrombosis and haemostasis : JTH 2023 Nov;21(11):3268-3278
Epigenetic activation of the TUSC3 gene as a potential therapy for XMEN disease.
Ding H, Li Y, Fang M, Chen J, Liu L, Lu Z, Hou J, Luo M
The Journal of allergy and clinical immunology 2023 Jun;151(6):1622-1633.e10
The Journal of allergy and clinical immunology 2023 Jun;151(6):1622-1633.e10
MAGT1 messenger RNA-corrected autologous T and natural killer cells for potential cell therapy in X-linked immunodeficiency with magnesium defect, Epstein-Barr virus infection and neoplasia disease.
Brault J, Meis RJ, Li L, Bello E, Liu T, Sweeney CL, Koontz SM, Dowdell K, Theobald N, Lee J, Allen C, Clark AB, Ravell JC, Lenardo MJ, Dahl GA, Malech HL, De Ravin SS
Cytotherapy 2021 Mar;23(3):203-210
Cytotherapy 2021 Mar;23(3):203-210
Mutations in MAGT1 lead to a glycosylation disorder with a variable phenotype.
Blommaert E, Péanne R, Cherepanova NA, Rymen D, Staels F, Jaeken J, Race V, Keldermans L, Souche E, Corveleyn A, Sparkes R, Bhattacharya K, Devalck C, Schrijvers R, Foulquier F, Gilmore R, Matthijs G
Proceedings of the National Academy of Sciences of the United States of America 2019 May 14;116(20):9865-9870
Proceedings of the National Academy of Sciences of the United States of America 2019 May 14;116(20):9865-9870
MicroRNA-148b regulates tumor growth of non-small cell lung cancer through targeting MAPK/JNK pathway.
Lu L, Liu Q, Wang P, Wu Y, Liu X, Weng C, Fang X, Li B, Cao X, Mao H, Wang L, Guan M, Wang W, Liu G
BMC cancer 2019 Mar 8;19(1):209
BMC cancer 2019 Mar 8;19(1):209
A Magnesium-Enriched 3D Culture System that Mimics the Bone Development Microenvironment for Vascularized Bone Regeneration.
Lin S, Yang G, Jiang F, Zhou M, Yin S, Tang Y, Tang T, Zhang Z, Zhang W, Jiang X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Jun 19;6(12):1900209
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2019 Jun 19;6(12):1900209
MagT1 regulated the odontogenic differentiation of BMMSCs induced byTGC-CM via ERK signaling pathway.
Zheng JM, Kong YY, Li YY, Zhang W
Stem cell research & therapy 2019 Jan 31;10(1):48
Stem cell research & therapy 2019 Jan 31;10(1):48
Comprehensive Interactome Analysis Reveals that STT3B Is Required for N-Glycosylation of Lassa Virus Glycoprotein.
Zhu S, Wan W, Zhang Y, Shang W, Pan X, Zhang LK, Xiao G
Journal of virology 2019 Dec 1;93(23)
Journal of virology 2019 Dec 1;93(23)
Construction of green fluorescence protein mutant to monitor STT3B-dependent N-glycosylation.
Kitajima T, Xue W, Liu YS, Wang CD, Liu SS, Fujita M, Gao XD
The FEBS journal 2018 Mar;285(5):915-928
The FEBS journal 2018 Mar;285(5):915-928
Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex.
Lin DL, Cherepanova NA, Bozzacco L, MacDonald MR, Gilmore R, Tai AW
mBio 2017 Jul 18;8(4)
mBio 2017 Jul 18;8(4)
The different expression of TRPM7 and MagT1 impacts on the proliferation of colon carcinoma cells sensitive or resistant to doxorubicin.
Cazzaniga A, Moscheni C, Trapani V, Wolf FI, Farruggia G, Sargenti A, Iotti S, Maier JA, Castiglioni S
Scientific reports 2017 Jan 17;7:40538
Scientific reports 2017 Jan 17;7:40538
Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens.
Marceau CD, Puschnik AS, Majzoub K, Ooi YS, Brewer SM, Fuchs G, Swaminathan K, Mata MA, Elias JE, Sarnow P, Carette JE
Nature 2016 Jul 7;535(7610):159-63
Nature 2016 Jul 7;535(7610):159-63
Mammalian cells lacking either the cotranslational or posttranslocational oligosaccharyltransferase complex display substrate-dependent defects in asparagine linked glycosylation.
Cherepanova NA, Gilmore R
Scientific reports 2016 Feb 11;6:20946
Scientific reports 2016 Feb 11;6:20946
Oxidoreductase activity is necessary for N-glycosylation of cysteine-proximal acceptor sites in glycoproteins.
Cherepanova NA, Shrimal S, Gilmore R
The Journal of cell biology 2014 Aug 18;206(4):525-39
The Journal of cell biology 2014 Aug 18;206(4):525-39
Second messenger role for Mg2+ revealed by human T-cell immunodeficiency.
Li FY, Chaigne-Delalande B, Kanellopoulou C, Davis JC, Matthews HF, Douek DC, Cohen JI, Uzel G, Su HC, Lenardo MJ
Nature 2011 Jul 27;475(7357):471-6
Nature 2011 Jul 27;475(7357):471-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 17430-1-AP(MAGT1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using 17430-1-AP and Rhodamine-labeled goat anti-rabbit IgG (red).Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17430-1-AP(MAGT1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 17430-1-AP(MAGT1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
