DPABH-25610

antibody from Creative Diagnostics

Targeting: GFI1 GFI-1, GFI1A, ZNF163

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

DPABH-25610

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DPABH-25610, RRID:AB_2518875

Product name

Rabbit Anti-Human GFI1 Polyclonal antibody

Antibody type

Polyclonal

Description

This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

50 uL