AMM03374G

antibody from Leading Biology

Targeting: CDKN2D INK4D, p19

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

AMM03374G

Provider

Leading Biology

Product name

CDKN2D Antibody (monoclonal) (M08)

Antibody type

Monoclonal

Description

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

2E11

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.