Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx015831 - Provider product page
- Provider
- Abbexa
- Product name
- Tyrosine-Protein Kinase CSK (CSK) Antibody
- Antibody type
- Monoclonal
- Description
- Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine.Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK.This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive.The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk.Tissue specificity: Expressed in lung and macrophages.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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