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- Antigen structure
- References [499]
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- Product number
- 15204-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15204-1-AP, RRID:AB_2292610
- Product name
- CHOP; GADD153 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CHOP; GADD153 antibody (Cat. #15204-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Combination of TrxR1 inhibitor and lenvatinib triggers ROS-dependent cell death in human lung cancer cells.
A 700 nm LED Light Activated Ru(II) Complex Destroys Tumor Cytoskeleton via Photosensitization and Photocatalysis.
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.
Zebrafish as a model to study PERK function in developmental diseases: implications for Wolcott-Rallison syndrome.
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Fucoxanthin ameliorates endoplasmic reticulum stress and inhibits apoptosis and alleviates intervertebral disc degeneration in rats by upregulating Sirt1.
Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress.
Apelin‑13 reduces high glucose‑induced mitochondrial dysfunction in cochlear hair cells by inhibiting endoplasmic reticulum stress.
Jolkinolide B synergistically potentiates the antitumor activity of GPX4 inhibitors via inhibiting TrxR1 in cisplatin-resistant bladder cancer cells.
Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.
Palmitic acid induces lipid droplet accumulation and senescence in nucleus pulposus cells via ER-stress pathway.
Urolithin A's Role in Alleviating Severe Acute Pancreatitis via Endoplasmic Reticulum-Mitochondrial Calcium Channel Modulation.
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
Inhibition of the endoplasmic reticulum stress-associated IRE-1 pathway alleviates preterm birth.
Remote ischemic postconditioning alleviates cerebral ischemic injury through SERCA2/endoplasmic reticulum stress-mediated apoptosis.
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signaling.
Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression.
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Melatonin alleviates endoplasmic reticulum stress and follicular granulosa cell apoptosis by regulating ATF4 to activate mTOR signaling pathway in chickens.
CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma.
p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function.
Inhibition of endoplasmic reticulum stress attenuates morphine protracted abstinence-induced anxiety-like behaviors in the male mice.
Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress.
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Empagliflozin reduces endoplasmic reticulum stress associated TXNIP/NLRP3 activation in tunicamycin-stimulated aortic endothelial cells.
Suppression of endoplasmic reticulum stress by 4-PBA enhanced atherosclerotic plaque stability via up-regulating CLOCK expression.
A beneficial adaptive role for CHOP in driving cell fate selection during ER stress.
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Sigma-1 receptor regulates the endoplasmic reticulum stress pathway in the protective mechanism of dexmedetomidine against hyperoxia-induced lung injury.
Dual targeting agent Thiotert inhibits the progression of glioblastoma by inducing ER stress-dependent autophagy.
Bioinformatics-driven discovery of silica nanoparticles induces apoptosis and renal damage via the unfolded protein response in NRK-52E cells and rat kidney.
Inhibition of cGAS-STING pathway by stress granules after activation of M2 macrophages by human mesenchymal stem cells against drug induced liver injury.
Buyang Huanwu decoction ameliorates bleomycin-induced pulmonary fibrosis in rats by attenuating the apoptosis of alveolar type II epithelial cells mediated by endoplasmic reticulum stress.
Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury.
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
Inhibiting the compensatory elevation of xCT collaborates with disulfiram/copper-induced GSH consumption for cascade ferroptosis and cuproptosis.
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Identification of hypoxia- and immune-related biomarkers in patients with ischemic stroke.
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
A novel bystander effect in tamoxifen treatment: PPIB derived from ER+ cells attenuates ER- cells via endoplasmic reticulum stress-induced apoptosis.
Repositioning of mifepristone as an integrated stress response activator to potentiate cisplatin efficacy in non-small cell lung cancer.
Qing Hua Chang Yin ameliorates chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and the NF-κB signalling pathway.
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury.
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression.
Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin.
Postantibiotic leukocyte enhancement-mediated reduction of intracellular bacteria by macrophages.
An anti-tumor protein PFAP specifically interacts with cholesterol-enriched membrane domains of A549 cells and induces paraptosis and endoplasmic reticulum stress.
Thromboxane A2/thromboxane A2 receptor axis facilitates hepatic insulin resistance and steatosis through endoplasmic reticulum stress in non-alcoholic fatty liver disease.
Rosmarinic acid mitigates acrylamide induced neurotoxicity via suppressing endoplasmic reticulum stress and inflammation in mouse hippocampus.
Melatonin inhibits tongue squamous cell carcinoma: Interplay of ER stress-induced apoptosis and autophagy with cell migration.
Targeting IDH1-Mutated Oligodendroglioma with Acid Ceramidase Inhibitors.
Triptolide induces apoptosis and cytoprotective autophagy by ROS accumulation via directly targeting peroxiredoxin 2 in gastric cancer cells.
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus.
The developmental regulator HAND1 inhibits gastric carcinogenesis through enhancing ER stress apoptosis via targeting CHOP and BAK which is augmented by cisplatin.
Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response.
HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress-driven hepatocellular carcinoma progression.
Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer.
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer.
The UFMylated ribosome-recognition protein SAYSD1 is predominantly expressed in spermatids but is dispensable for fertility in mice.
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
Bavachin induces liver injury and cell apoptosis by targeting Wnt/β-catenin/DRP1 signaling pathway mediated mitochondrial dysfunction.
A selective ER-phagy exerts neuroprotective effects via modulation of α-synuclein clearance in parkinsonian models.
Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease.
Diosmetin-7-O-β-D-glucopyranoside suppresses endothelial-mesenchymal transformation through endoplasmic reticulum stress in cardiac fibrosis.
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Narirutin ameliorates alcohol-induced liver injury by targeting MAPK14 in zebrafish larvae.
Caffeic acid's role in mitigating polycystic ovary syndrome by countering apoptosis and ER stress triggered by oxidative stress.
Undesirable ER stress induced by bavachin contributed to follicular atresia in zebrafish ovary.
Knockdown of NR3C1 inhibits the proliferation and migration of clear cell renal cell carcinoma through activating endoplasmic reticulum stress-mitophagy.
A beneficial adaptive role for CHOP in driving cell fate selection during ER stress.
Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis.
IKVAV peptide-containing hydrogel decreases fibrous scar after spinal cord injury by inhibiting fibroblast migration and activation.
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.
Metformin combined with glucose starvation synergistically suppress triple-negative breast cancer by enhanced unfolded protein response.
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Role of SIRT2 in intestinal barrier under cold exposure.
Key Subdomains of Cerebral Dopamine Neurotrophic Factor Regulate Its Protective Function in 6-Hydroxydopamine-Lesioned PC12 Cells.
Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma.
Mannose-doped metal-organic frameworks induce tumor cell pyroptosis via the PERK pathway.
Systemic deuteration of SCID mice using the water-isotopologue deuterium oxide (D(2) O) inhibits tumor growth in an orthotopic bioluminescent model of human pancreatic ductal adenocarcinoma.
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4.
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms.
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Atorvastatin prevents endoplasmic reticulum stress-mediated apoptosis via the Nrf2/HO-1 signaling pathway in TBI mice.
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Scalp acupuncture alleviates cerebral ischemic stroke-induced motor dysfunction in rats via regulating endoplasmic reticulum stress and ER-phagy.
[Cordycepin, a metabolite of Cordyceps militaris, inhibits xenograft tumor growth of tongue squamous cell carcinoma in nude mice].
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Ginsenoside Rg1 regulates autophagy and endoplasmic reticulum stress via the AMPK/mTOR and PERK/ATF4/CHOP pathways to alleviate alcohol‑induced myocardial injury.
Bavachin protects against diet-induced hepatic steatosis and obesity in mice.
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Xylanase improves the intestinal barrier function of Nile tilapia (Oreochromis niloticus) fed with soybean (Glycine max) meal.
Identification of EGF Receptor and Thrombospondin-1 as Endogenous Targets of ER-Associated Degradation Enhancer EDEM1 in HeLa Cells.
Nobiletin inhibits de novo FA synthesis to alleviate gastric cancer progression by regulating endoplasmic reticulum stress.
Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response.
Identification of genomic binding sites and direct target genes for the transcription factor DDIT3/CHOP.
Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress.
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Chlorin e6-induced photodynamic effect facilitates immunogenic cell death of lung cancer as a result of oxidative endoplasmic reticulum stress and DNA damage.
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes.
Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds with Endoplasmic Reticulum Stress-Relieving Properties for Promoted Scarless Wound Healing.
Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice.
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells.
Apelin-13 alleviates contrast-induced acute kidney injury by inhibiting endoplasmic reticulum stress.
Lithium chloride induces apoptosis by activating endoplasmic reticulum stress in pancreatic cancer.
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Betaine ameliorates heat stress-induced apoptosis by affecting oxidative and endoplasmic reticulum stress in mouse Leydig cells.
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
Tanshinone IIA ameliorates experimental diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress in cardiomyocytes via SIRT1.
VPS34-IN1 induces apoptosis of ER+ breast cancer cells via activating PERK/ATF4/CHOP pathway.
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Zinc deficiency causes oxidative stress, endoplasmic reticulum stress, apoptosis and inflammation in hepatocytes in grass carp.
SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Rosmarinic acid alleviates intestinal inflammatory damage and inhibits endoplasmic reticulum stress and smooth muscle contraction abnormalities in intestinal tissues by regulating gut microbiota.
cFLIP(L) Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Endoplasmic Reticulum Stress.
Hydrogen sulfide regulates SERCA2a SUMOylation by S-Sulfhydration of SENP1 to ameliorate cardiac systole-diastole function in diabetic cardiomyopathy.
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy.
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo.
Citrinin Exposure Induced Testicular Damage and Spermatogenesis Disorder by Triggering Endoplasmic Reticulum Stress.
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Effects of folic acid on oxidative damage of kidney in lead-exposed rats.
Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress.
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells.
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
Upregulation of Glutaminyl Cyclase Contributes to ERS-Induced Apoptosis in PC12 Cells.
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis.
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Inhibition of the integrated stress response reverses oxidative stress damage-induced postoperative cognitive dysfunction.
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress.
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Cryptotanshinone alleviates myocardial ischemia and reperfusion injury in rats to mitigate ER stress-dependent apoptosis by modulating the JAK1/STAT3 axis.
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Pinelliae rhizoma alleviated acute lung injury induced by lipopolysaccharide via suppressing endoplasmic reticulum stress-mediated NLRP3 inflammasome.
Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT.
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics.
Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction.
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma.
RRBP1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype.
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Identification of Ferroptotic Genes in Spinal Cord Injury at Different Time Points: Bioinformatics and Experimental Validation.
Role of Mydgf in the regulation of hypoxia/reoxygenation-induced apoptosis in cardiac microvascular endothelial cells.
Acacetin antagonized lipotoxicity in pancreatic β-cells via ameliorating oxidative stress and endoplasmic reticulum stress.
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Role of hair follicles in the pathogenesis of arsenical-induced cutaneous damage.
Zearalenone Promotes LPS-Induced Oxidative Stress, Endoplasmic Reticulum Stress, and Accelerates Bovine Mammary Epithelial Cell Apoptosis.
Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells.
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage.
ER stress transforms random olfactory receptor choice into axon targeting precision.
A systems biological analysis of the ATF4-GADD34-CHOP regulatory triangle upon endoplasmic reticulum stress.
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Paxlovid accelerates cartilage degeneration and senescence through activating endoplasmic reticulum stress and interfering redox homeostasis.
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma.
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
diTFPP, a Phenoxyphenol, Sensitizes Hepatocellular Carcinoma Cells to C(2)-Ceramide-Induced Autophagic Stress by Increasing Oxidative Stress and ER Stress Accompanied by LAMP2 Hypoglycosylation.
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes.
Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function.
Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78).
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells.
Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction.
The Impact of NRF2 Inhibition on Drug-Induced Colon Cancer Cell Death and p53 Activity: A Pilot Study.
Protective Effects of Taraxasterol against Deoxynivalenol-Induced Damage to Bovine Mammary Epithelial Cells.
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
FAdV-4 induce autophagy via the endoplasmic reticulum stress-related unfolded protein response.
Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis.
Quinoa Reduces High-Fat Diet-Induced Obesity in Mice via Potential Microbiota-Gut-Brain-Liver Interaction Mechanisms.
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress.
Intravenously transplanted mesenchymal stromal cells: a new endocrine reservoir for cardioprotection.
Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer.
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.
GBP5 promotes liver injury and inflammation by inducing hepatocyte apoptosis.
TRPV4 contributes to ER stress and inflammation: implications for Parkinson's disease.
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation.
Nrf2 activation mediates the protection of mouse Sertoli Cells damage under acute heat stress conditions.
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Involvement of increased endoplasmic reticulum stress in the development of cataracts in BALB.NCT-Cpox(nct) mice.
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
ATP6V1H deficiency impairs glucose tolerance by augmenting endoplasmic reticulum stress in high fat diet fed mice.
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Jolkinolide B sensitizes bladder cancer to mTOR inhibitors via dual inhibition of Akt signaling and autophagy.
Endoplasmic reticulum stress mediates parathyroid hormone-induced apoptosis in vascular smooth muscle cells.
The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.
Exosome modification to better alleviates endoplasmic reticulum stress induced chondrocyte apoptosis and osteoarthritis.
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response.
Effects of natural 24-epibrassinolide on inducing apoptosis and restricting metabolism in hepatocarcinoma cells.
Deficiency of CFB attenuates renal tubulointerstitial damage by inhibiting ceramide synthesis in diabetic kidney disease.
African Swine Fever Virus MGF110-7L Induces Host Cell Translation Suppression and Stress Granule Formation by Activating the PERK/PKR-eIF2α Pathway.
Diverse injury responses of human oligodendrocyte to mediators implicated in multiple sclerosis.
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
The IRE1/JNK signaling pathway regulates inflammation cytokines and production of glomerular extracellular matrix in the acute kidney injury to chronic kidney disease transition.
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis.
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells.
Azoramide ameliorated tachypacing-induced injury of atrial myocytes differentiated from human induced pluripotent stem cell by regulating endoplasmic reticulum stress.
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway.
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Glucocorticoids protect HEI-OC1 cells from tunicamycin-induced cell damage via inhibiting endoplasmic reticulum stress.
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Interventional Efects of the Topical of "Sanse Powder" Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis.
IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression.
Extracts of Vine Tea Improve Diet-Induced Non-Alcoholic Steatohepatitis Through AMPK-LXRα Signaling.
Kaempferol Alleviates Steatosis and Inflammation During Early Non-Alcoholic Steatohepatitis Associated With Liver X Receptor α-Lysophosphatidylcholine Acyltransferase 3 Signaling Pathway.
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Berberine Attenuates Cerebral Ischemia-Reperfusion Injury Induced Neuronal Apoptosis by Down-Regulating the CNPY2 Signaling Pathway.
Lamprey Immune Protein Mediates Apoptosis of Lung Cancer Cells Via the Endoplasmic Reticulum Stress Signaling Pathway.
Selenium deficiency causes apoptosis through endoplasmic reticulum stress in swine small intestine.
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment.
Role of UPR Sensor Activation in Cell Death-Survival Decision of Colon Cancer Cells Stressed by DPE Treatment.
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH.
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Expression liabilities in a four-chain bispecific molecule.
CK1δ stimulates ubiquitination-dependent proteasomal degradation of ATF4 to promote chemoresistance in gastric Cancer.
IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation.
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
TLR4 deletion increases basal energy expenditure and attenuates heart apoptosis and ER stress but mitigates the training-induced cardiac function and performance improvement.
Suppression of alveolar bone resorption by salubrinal in a mouse model of periodontal disease.
Autophagy triggers endoplasmic reticulum stress and C/EBP homologous protein-mediated apoptosis in OGD/R-treated neurons in a caspase-12-independent manner.
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Near-infrared emission Cu, N-doped carbon dots for human umbilical vein endothelial cell labeling and their biocompatibility in vitro.
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway.
4-Acetylantroquinonol B ameliorates nonalcoholic steatohepatitis by suppression of ER stress and NLRP3 inflammasome activation.
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Combination of Palmitic Acid and Methylseleninic Acid Induces Mitochondria-Dependent Apoptosis via Attenuation of the IRE1α Arm and Enhancement of CHOP in Hepatoma.
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
Polybrominated diphenyl ethers quinone-induced intracellular protein oxidative damage triggers ubiquitin-proteasome and autophagy-lysosomal system activation in LO2 cells.
Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.
Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung.
Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis.
Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells.
Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons.
Thrombospondin 1-induced exosomal proteins attenuate hypoxia-induced paraptosis in corneal epithelial cells and promote wound healing.
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo.
Cigarette smoke extracts induce apoptosis in Raw264.7 cells via endoplasmic reticulum stress and the intracellular Ca(2+)/P38/STAT1 pathway.
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Reticulocalbin 1 is required for proliferation and migration of non-small cell lung cancer cells regulated by osteoblast-conditioned medium.
Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice.
Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in primary Sjögren's syndrome.
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Long non-coding RNA RP5-821D11.7 promotes proliferation, migration, and epithelial-mesenchymal transition in glioma and glioma stem-like cells.
Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity.
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
Integration of Metabolomics and Transcriptomics Reveals Ketone Body and Lipid Metabolism Disturbance Related to ER Stress in the Liver.
KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats.
Estrogen Regulates Endoplasmic Reticulum Stress-Mediated Apoptosis by ERK-p65 Pathway to Promote Endometrial Angiogenesis.
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress.
Nanosecond pulsed electric fields induce the integrated stress response via reactive oxygen species-mediated heme-regulated inhibitor (HRI) activation.
Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway.
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
Role of Endoplasmic Reticulum Stress in Otitis Media.
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Apigetrin ameliorates streptozotocin-induced pancreatic β-cell damages via attenuating endoplasmic reticulum stress.
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.
Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.
FABP4 inhibitor BMS309403 protects against hypoxia-induced H9c2 cardiomyocyte apoptosis through attenuating endoplasmic reticulum stress.
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE(-/-) mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats.
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP(+)-induced cell model of Parkinson's disease.
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.
Proscillaridin A slows the prostate cancer progression through triggering the activation of endoplasmic reticulum stress.
A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary.
Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.
Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum.
Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation.
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
4-Phenylbutyrate Prevents Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Heatstroke in the Intestines of Mice.
ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression.
TMEM216 Deletion Causes Mislocalization of Cone Opsin and Rhodopsin and Photoreceptor Degeneration in Zebrafish.
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Minocycline induces apoptosis of photoreceptor cells by regulating ER stress.
Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway.
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
N-glycosylation of uterine endometrium determines its receptivity.
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Melatonin protects against Epirubicin-induced ovarian damage.
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Mitochondrial serine protease Omi/HtrA2 accentuates brain ischemia/reperfusion injury in rats and oxidative stress injury in vitro by modulating mitochondrial stress proteins CHOP and ClpP and physically interacting with mitochondrial fusion protein OPA1.
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Phosphorylation of eIF2α signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner.
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
The protective effects of phoenixin-14 against lipopolysaccharide-induced inflammation and inflammasome activation in astrocytes.
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol.
IL13Rα1 protects against rheumatoid arthritis by combating the apoptotic resistance of fibroblast-like synoviocytes.
25-Hydroxycholesterol promotes vascular calcification via activation of endoplasmic reticulum stress.
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
Artemisinin and dihydroartemisinin promote β-cell apoptosis induced by palmitate via enhancing ER stress.
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells.
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
Autophagy Activation Is Involved in Acidic Fibroblast Growth Factor Ameliorating Parkinson's Disease via Regulating Tribbles Homologue 3.
Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway.
Effect of endoplasmic reticulum calcium on paraquat‑induced apoptosis of human lung type II alveolar epithelial A549 cells.
Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress.
Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line.
Lysosomal dysfunction is associated with persistent lung injury in dams caused by pregnancy exposure to carbon black nanoparticles.
Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway.
Endoplasmic reticulum stress and autophagy contribute to cadmium-induced cytotoxicity in retinal pigment epithelial cells.
Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity.
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.
Dihydroartemisinin attenuates alcoholic fatty liver through regulation of lipin-1 signaling.
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Adenoviral TMBIM6 vector attenuates ER-stress-induced apoptosis in a neonatal hypoxic-ischemic rat model.
Structure-toxicity relationships of saturated and unsaturated free fatty acids for elucidating the lipotoxic effects in human EndoC-βH1 beta-cells.
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration.
Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats.
A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity.
Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability.
A pectic polysaccharide from water decoction of Xinjiang Lycium barbarum fruit protects against intestinal endoplasmic reticulum stress.
Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo.
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na(+) and Ca(2+) handling.
Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells.
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS.
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress.
Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress.
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin.
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress.
Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway.
TMEM30A deficiency in endothelial cells impairs cell proliferation and angiogenesis.
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress.
A comparative study of toxicity of TiO(2), ZnO, and Ag nanoparticles to human aortic smooth-muscle cells.
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
Effects of knee loading on obesity-related non-alcoholic fatty liver disease in an ovariectomized mouse model with high-fat diet.
TMCO1 is essential for ovarian follicle development by regulating ER Ca(2+) store of granulosa cells.
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Benefits of combination low-dose pioglitazone plus fish oil on aged type 2 diabetes mice.
ERp44 depletion exacerbates ER stress and aggravates diabetic nephropathy in db/db mice.
Nordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet-Induced Metabolic Dysfunction in Mice.
Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78.
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
18β-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma.
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
STF-083010, an inhibitor of XBP1 splicing, attenuates acute renal failure in rats by suppressing endoplasmic reticulum stress-induced apoptosis and inflammation.
Dihydroartemisinin inhibits ER stress-mediated mitochondrial pathway to attenuate hepatocyte lipoapoptosis via blocking the activation of the PI3K/Akt pathway.
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Endoplasmic Reticulum Stress in the Dorsal Root Ganglion Contributes to the Development of Pain Hypersensitivity after Nerve Injury.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Transthyretin Exerts Pro-Apoptotic Effects in Human Retinal Microvascular Endothelial Cells Through a GRP78-Dependent Pathway in Diabetic Retinopathy.
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H(2)S system: Role of oxidative stress and endoplasmic reticulum stress.
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Garcinol from Garcinia indica Downregulates Cancer Stem-like Cell Biomarker ALDH1A1 in Nonsmall Cell Lung Cancer A549 Cells through DDIT3 Activation.
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Identification of Novel SCIRR69-Interacting Proteins During ER Stress Using SILAC-Immunoprecipitation Quantitative Proteomics Approach.
Exogenous H(2)S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activation.
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
The reproductive toxicology of male SD rats after PM(2.5) exposure mediated by the stimulation of endoplasmic reticulum stress.
Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats.
Role of endoplasmic reticulum stress in disuse osteoporosis.
Oleate attenuates palmitate-induced endoplasmic reticulum stress and apoptosis in placental trophoblasts.
Dimethylarginine Dimethylaminohydrolase 1 Protects Against High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice.
Reduced expression of citrate synthase leads to excessive superoxide formation and cell apoptosis.
4-Phenylbutyric Acid Induces Protection against Pulmonary Arterial Hypertension in Rats.
Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Ablation of Perk in Schwann Cells Improves Myelination in the S63del Charcot-Marie-Tooth 1B Mouse.
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Protective effects of fish oil and pioglitazone on pancreatic tissue in obese KK mice with type 2 diabetes.
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
The protective effect of the earthworm active ingredients on hepatocellular injury induced by endoplasmic reticulum stress.
Quinocetone triggered ER stress-induced autophagy via ATF6/DAPK1-modulated mAtg9a trafficking.
Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat chloride-induced hypoxia.
Evaluation of cytotoxic activity of titanocene difluorides and determination of their mechanism of action in ovarian cancer cells.
Endoplasmic reticulum stress is involved in the lidocaine-induced apoptosis in SH-SY5Y neuroblastoma cells.
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Role of Endoplasmic Reticulum Stress in Brain Damage After Cardiopulmonary Resuscitation in Rats.
Inhibition of c-Src/p38 MAPK pathway ameliorates renal tubular epithelial cells apoptosis in db/db mice.
O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.
Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma.
Down-regulation of PERK-ATF4-CHOP pathway by Astragaloside IV is associated with the inhibition of endoplasmic reticulum stress-induced podocyte apoptosis in diabetic rats.
Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants.
Protein degradation and quality control in cells from laforin and malin knockout mice.
Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway.
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
Arsenic trioxide alleviates airway hyperresponsiveness and promotes apoptosis of CD4+ T lymphocytes: evidence for involvement of the ER stress-CHOP pathway.
Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Zheng P, Xia Y, Shen X, Lu H, Chen Y, Xu C, Qiu C, Zhang Y, Zou P, Cui R, Huang X
International journal of biological sciences 2024;20(1):249-264
International journal of biological sciences 2024;20(1):249-264
A 700 nm LED Light Activated Ru(II) Complex Destroys Tumor Cytoskeleton via Photosensitization and Photocatalysis.
Dao A, Chen S, Pan L, Ren Q, Wang X, Wu H, Gong Q, Chen Z, Ji S, Ru J, Zhu H, Liang C, Zhang P, Xia H, Huang H
Advanced healthcare materials 2024 Sep;13(23):e2400956
Advanced healthcare materials 2024 Sep;13(23):e2400956
NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.
Shen NX, Qu XC, Yu J, Fan CX, Min FL, Li LY, Zhang MR, Li BM, Wang J, He N, Liao WP, Shi YW, Li WB
Molecular neurobiology 2024 Nov;61(11):8518-8530
Molecular neurobiology 2024 Nov;61(11):8518-8530
Zebrafish as a model to study PERK function in developmental diseases: implications for Wolcott-Rallison syndrome.
Almeida LM, Lima LP, Oliveira NAS, Silva RFO, Sousa B, Bessa J, Pinho BR, Oliveira JMA
bioRxiv : the preprint server for biology 2024 Nov 5;
bioRxiv : the preprint server for biology 2024 Nov 5;
Epigallocatechin gallate alleviated the in vivo toxicity of ZnO nanoparticles to mouse intestine.
Wang C, Huang C, Cao Y
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Journal of applied toxicology : JAT 2024 May;44(5):686-698
Fucoxanthin ameliorates endoplasmic reticulum stress and inhibits apoptosis and alleviates intervertebral disc degeneration in rats by upregulating Sirt1.
Teng C, Wu J, Zhang Z, Wang J, Yang Y, Dong C, Wu L, Lin Z, Hu Y, Wang J, Zhang X, Lin Z
Phytotherapy research : PTR 2024 May;38(5):2114-2127
Phytotherapy research : PTR 2024 May;38(5):2114-2127
Mechanism of Qili Qiangxin Capsule for Heart Failure Based on miR133a-Endoplasmic Reticulum Stress.
Ji XD, Yang D, Cui XY, Lou LX, Nie B, Zhao JL, Zhao MJ, Wu AM
Chinese journal of integrative medicine 2024 May;30(5):398-407
Chinese journal of integrative medicine 2024 May;30(5):398-407
Apelin‑13 reduces high glucose‑induced mitochondrial dysfunction in cochlear hair cells by inhibiting endoplasmic reticulum stress.
Huo Z, Gu J, He T
Experimental and therapeutic medicine 2024 May;27(5):226
Experimental and therapeutic medicine 2024 May;27(5):226
Jolkinolide B synergistically potentiates the antitumor activity of GPX4 inhibitors via inhibiting TrxR1 in cisplatin-resistant bladder cancer cells.
Sang J, Liu CK, Liu J, Luo GC, Zheng WJ, Bai Y, Jiang DY, Pu JN, An S, Xu TR
Biochemical pharmacology 2024 May;223:116194
Biochemical pharmacology 2024 May;223:116194
Synergistic targeting of TrxR1 and ATM/AKT pathway in human colon cancer cells.
Shen X, Xia Y, Lu H, Zheng P, Wang J, Chen Y, Xu C, Qiu C, Zhang Y, Xiao Z, Zou P, Cui R, Ni D
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116507
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 May;174:116507
Palmitic acid induces lipid droplet accumulation and senescence in nucleus pulposus cells via ER-stress pathway.
Chen X, Chen K, Hu J, Dong Y, Zheng M, Jiang J, Hu Q, Zhang W
Communications biology 2024 May 7;7(1):539
Communications biology 2024 May 7;7(1):539
Urolithin A's Role in Alleviating Severe Acute Pancreatitis via Endoplasmic Reticulum-Mitochondrial Calcium Channel Modulation.
Kang H, Hu Q, Yang Y, Huang G, Li J, Zhao X, Zhu L, Su H, Tang W, Wan M
ACS nano 2024 May 28;18(21):13885-13898
ACS nano 2024 May 28;18(21):13885-13898
Esculin suppresses the PERK-eIF2α-CHOP pathway by enhancing SIRT1 expression in oxidative stress-induced rat chondrocytes, mitigating osteoarthritis progression in a rat model.
Cheng Z, Liu Z, Liu C, Yang A, Miao H, Bai X
International immunopharmacology 2024 May 10;132:112061
International immunopharmacology 2024 May 10;132:112061
Inhibition of the endoplasmic reticulum stress-associated IRE-1 pathway alleviates preterm birth.
Qiu L, Liu H, Chen S, Wu Y, Yan J
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Mar;91(3):e13826
American journal of reproductive immunology (New York, N.Y. : 1989) 2024 Mar;91(3):e13826
Remote ischemic postconditioning alleviates cerebral ischemic injury through SERCA2/endoplasmic reticulum stress-mediated apoptosis.
Chen W, Li M, Lei X, Cheng Y, Wu X, Sun X, Wu Y, Li Z, Luo G, Wei M
Microscopy research and technique 2024 Mar;87(3):424-433
Microscopy research and technique 2024 Mar;87(3):424-433
D-pinitol alleviates diabetic cardiomyopathy by inhibiting the optineurin-mediated endoplasmic reticulum stress and glycophagy signaling pathway.
Li X, Yu X, Yu F, Fu C, Zhao W, Liu X, Dai C, Gao H, Cheng M, Li B
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
Phytotherapy research : PTR 2024 Mar;38(3):1681-1694
LanGui tea, an herbal medicine formula, protects against binge alcohol-induced acute liver injury by activating AMPK-NLRP3 signaling.
Gu M, Chen YJ, Feng YR, Tang ZP
Chinese medicine 2024 Mar 4;19(1):41
Chinese medicine 2024 Mar 4;19(1):41
Prenatal inflammation exposure accelerates lung cancer tumorigenesis in offspring mouse: possible links to IRE1α/XBP1-mediated M2-like polarization of TAMs and PD-L1 up-expression.
Ma J, Tan J, Zhang W, Bai M, Liu K
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):88
Cancer immunology, immunotherapy : CII 2024 Mar 30;73(5):88
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
Xie W, Deng L, Qian R, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Patil SV, Kaipa BR, Ranshing S, Sundaresan Y, Millar JC, Nagarajan B, Kiehlbauch C, Zhang Q, Jain A, Searby CC, Scheetz TE, Clark AF, Sheffield VC, Zode GS
Scientific reports 2024 Mar 23;14(1):6958
Scientific reports 2024 Mar 23;14(1):6958
Effects of gas signaling molecule SO(2) in cardiac functions of hyperthyroid rats.
Yang Q, Yang T, Liu X, Liu S, Liu W, Nie L, Chu C, Yang J
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2024 Mar 1;28(2):129-143
Melatonin alleviates endoplasmic reticulum stress and follicular granulosa cell apoptosis by regulating ATF4 to activate mTOR signaling pathway in chickens.
Hao EY, Liu XL, Chen XY, Xue H, Su BF, Chen YF, Wang DH, Shi L, Bai K, Hou F, Hou JK, Bao HL, Chen H
Poultry science 2024 Jun;103(6):103656
Poultry science 2024 Jun;103(6):103656
CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma.
Zhuo R, Zhang Z, Chen Y, Li G, Du S, Guo X, Yang R, Tao Y, Li X, Fang F, Xie Y, Wu D, Yang Y, Yang C, Yin H, Qian G, Wang H, Yu J, Jia S, Zhu F, Feng C, Wang J, Xu Y, Li Z, Shi L, Wang X, Pan J, Wang J
Cancer letters 2024 Jun 1;591:216882
Cancer letters 2024 Jun 1;591:216882
p97 inhibits integrated stress response-induced neuronal apoptosis after subarachnoid hemorrhage in mice by enhancing proteasome function.
Cheng W, Wei B, Liu W, Jin L, Guo S, Ding M, Liu Y, Fan H, Li R, Zhang X, He X, Li X, Duan C
Experimental neurology 2024 Jul;377:114778
Experimental neurology 2024 Jul;377:114778
Inhibition of endoplasmic reticulum stress attenuates morphine protracted abstinence-induced anxiety-like behaviors in the male mice.
Liu L, Wu J, Zhang C, Cao T, Lu Y, He Z, Li Z
Brain research 2024 Jul 15;1835:148930
Brain research 2024 Jul 15;1835:148930
Copper exposure induces mitochondrial dysfunction and hepatotoxicity via the induction of oxidative stress and PERK/ATF4 -mediated endoplasmic reticulum stress.
Li M, Tang S, Velkov T, Shen J, Dai C
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124145
Environmental pollution (Barking, Essex : 1987) 2024 Jul 1;352:124145
Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury.
Liu YT, Zhang H, Duan SB, Wang JW, Chen H, Zhan M, Zhang W, Li AM, Liu Y, Yang Y, Yang S
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Antioxidants & redox signaling 2024 Jan;40(1-3):16-39
Empagliflozin reduces endoplasmic reticulum stress associated TXNIP/NLRP3 activation in tunicamycin-stimulated aortic endothelial cells.
Campeau MA, Leask RL
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):267-279
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jan;397(1):267-279
Suppression of endoplasmic reticulum stress by 4-PBA enhanced atherosclerotic plaque stability via up-regulating CLOCK expression.
Zhu G, Gao H, Li Y, Li X, Yang X, Wang C, Guo Z, Fan H, Fan L
Pathology, research and practice 2024 Jan;253:154969
Pathology, research and practice 2024 Jan;253:154969
A beneficial adaptive role for CHOP in driving cell fate selection during ER stress.
Liu K, Zhao C, Adajar RC, DeZwaan-McCabe D, Rutkowski DT
EMBO reports 2024 Jan;25(1):228-253
EMBO reports 2024 Jan;25(1):228-253
Maternal obstructive sleep apnea aggravates metabolic dysfunction-associated fatty liver disease via HMGB1-TLR4 signaling-mediated endoplasmic reticulum stress in male offspring rats.
Wang R, Feng W, Wang Y, Jiang Y, Lin Y, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166889
Sigma-1 receptor regulates the endoplasmic reticulum stress pathway in the protective mechanism of dexmedetomidine against hyperoxia-induced lung injury.
Huang M, Wang J, Zhai M, Liu J, Zhu Y, Zhang Y, Zhao J, Wang H, Sun J, Yu H, Liu C
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166885
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166885
Dual targeting agent Thiotert inhibits the progression of glioblastoma by inducing ER stress-dependent autophagy.
Dong J, Qian Y, Zhang W, Wang Q, Jia M, Yue J, Fan Z, Jiang Y, Wang L, Wang Y, Huang Z, Yu L, Wang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:115867
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Jan;170:115867
Bioinformatics-driven discovery of silica nanoparticles induces apoptosis and renal damage via the unfolded protein response in NRK-52E cells and rat kidney.
Liu N, Li M, Pang H, Tiantian T, Li X, Su Y, Jin M, Wu H, Qian C, Sun M
Computers in biology and medicine 2024 Jan;168:107816
Computers in biology and medicine 2024 Jan;168:107816
Inhibition of cGAS-STING pathway by stress granules after activation of M2 macrophages by human mesenchymal stem cells against drug induced liver injury.
Wang Y, She S, Li W, Zhu J, Li X, Yang F, Dai K
Molecular immunology 2024 Jan;165:42-54
Molecular immunology 2024 Jan;165:42-54
Buyang Huanwu decoction ameliorates bleomycin-induced pulmonary fibrosis in rats by attenuating the apoptosis of alveolar type II epithelial cells mediated by endoplasmic reticulum stress.
Zhou P, Wu X, Chen K, Du J, Wang F
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117300
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117300
Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury.
Wang B, He X, Zhang J, Zhang Y
Biochemical and biophysical research communications 2024 Jan 15;692:149347
Biochemical and biophysical research communications 2024 Jan 15;692:149347
Patulin induces ROS-dependent cardiac cell toxicity by inducing DNA damage and activating endoplasmic reticulum stress apoptotic pathway.
Zhang B, Huang C, Xu D, Huang K, Li Y, Jiao L, Fu B, Li S, Li Y
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
Ecotoxicology and environmental safety 2024 Jan 1;269:115784
Inhibiting the compensatory elevation of xCT collaborates with disulfiram/copper-induced GSH consumption for cascade ferroptosis and cuproptosis.
Zhang P, Zhou C, Ren X, Jing Q, Gao Y, Yang C, Shen Y, Zhou Y, Hu W, Jin F, Xu H, Yu L, Liu Y, Tong X, Li Y, Wang Y, Du J
Redox biology 2024 Feb;69:103007
Redox biology 2024 Feb;69:103007
Methane-Rich Saline Suppresses ER-Mitochondria Contact and Activation of the NLRP3 Inflammasome by Regulating the PERK Signaling Pathway to Ameliorate Intestinal Ischemia‒Reperfusion Injury.
Li Z, Wang B, Tian L, Zheng B, Zhao X, Liu R
Inflammation 2024 Feb;47(1):376-389
Inflammation 2024 Feb;47(1):376-389
Identification of hypoxia- and immune-related biomarkers in patients with ischemic stroke.
Zhang H, Sun J, Zou P, Huang Y, Yang Q, Zhang Z, Luo P, Jiang X
Heliyon 2024 Feb 29;10(4):e25866
Heliyon 2024 Feb 29;10(4):e25866
Lysine demethylase KDM3A alleviates hyperoxia-induced bronchopulmonary dysplasia in mice by promoting ETS1 expression.
Yang M, Chen Y, Huang X, Shen F, Meng Y
Experimental cell research 2024 Feb 15;435(2):113945
Experimental cell research 2024 Feb 15;435(2):113945
A novel bystander effect in tamoxifen treatment: PPIB derived from ER+ cells attenuates ER- cells via endoplasmic reticulum stress-induced apoptosis.
Yang T, Li W, Zhou J, Xu M, Huang Z, Ming J, Huang T
Cell death & disease 2024 Feb 15;15(2):147
Cell death & disease 2024 Feb 15;15(2):147
Repositioning of mifepristone as an integrated stress response activator to potentiate cisplatin efficacy in non-small cell lung cancer.
Namkaew J, Zhang J, Yamakawa N, Hamada Y, Tsugawa K, Oyadomari M, Miyake M, Katagiri T, Oyadomari S
Cancer letters 2024 Feb 1;582:216509
Cancer letters 2024 Feb 1;582:216509
Qing Hua Chang Yin ameliorates chronic colitis in mice by inhibiting PERK-ATF4-CHOP pathway of ER stress and the NF-κB signalling pathway.
Liu L, Chen Y, Han Y, Zhang X, Wu Y, Lin J, Cao L, Wu M, Zheng H, Fang Y, Wei L, Sferra TJ, Jafri A, Ke X, Peng J, Shen A
Pharmaceutical biology 2024 Dec;62(1):607-620
Pharmaceutical biology 2024 Dec;62(1):607-620
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Li L, Jin RJ, Ji L
Environmental toxicology 2024 Dec;39(12):5382-5390
Environmental toxicology 2024 Dec;39(12):5382-5390
Sex-related differences in SIRT3-mediated mitochondrial dynamics in renal ischemia/reperfusion injury.
Yao H, Zhao H, Du Y, Zhang Y, Li Y, Zhu H
Translational research : the journal of laboratory and clinical medicine 2024 Aug;270:1-12
Translational research : the journal of laboratory and clinical medicine 2024 Aug;270:1-12
ATF6 supports lysosomal function in tumor cells to enable ER stress-activated macroautophagy and CMA: impact on mutant TP53 expression.
Benedetti R, Romeo MA, Arena A, Gilardini Montani MS, D'Orazi G, Cirone M
Autophagy 2024 Aug;20(8):1854-1867
Autophagy 2024 Aug;20(8):1854-1867
Ethanol-Induced Hepatic Ferroptosis Is Mediated by PERK-Dependent MAMs Formation: Preventive Role of Quercetin.
Lin H, Guo X, Liu J, Tang Y, Chen L, Chen H, Zhao Y, Wang L, Li H, Yu J, Yao P
Molecular nutrition & food research 2024 Apr;68(7):e2300343
Molecular nutrition & food research 2024 Apr;68(7):e2300343
Postantibiotic leukocyte enhancement-mediated reduction of intracellular bacteria by macrophages.
Wu Y, Gong X, Shen J, Zhu K
Journal of advanced research 2024 Apr;58:117-128
Journal of advanced research 2024 Apr;58:117-128
An anti-tumor protein PFAP specifically interacts with cholesterol-enriched membrane domains of A549 cells and induces paraptosis and endoplasmic reticulum stress.
Liu MH, Liu ZK, Liu F
International journal of biological macromolecules 2024 Apr;264(Pt 2):130690
International journal of biological macromolecules 2024 Apr;264(Pt 2):130690
Thromboxane A2/thromboxane A2 receptor axis facilitates hepatic insulin resistance and steatosis through endoplasmic reticulum stress in non-alcoholic fatty liver disease.
Dai Y, Xu R, Chen J, Fang J, Zhang H, Li H, Chen W
British journal of pharmacology 2024 Apr;181(7):967-986
British journal of pharmacology 2024 Apr;181(7):967-986
Rosmarinic acid mitigates acrylamide induced neurotoxicity via suppressing endoplasmic reticulum stress and inflammation in mouse hippocampus.
Wang TB, He Y, Li RC, Yu YX, Liu Y, Qi ZQ
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155448
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Apr;126:155448
Melatonin inhibits tongue squamous cell carcinoma: Interplay of ER stress-induced apoptosis and autophagy with cell migration.
Liu H, Zheng Y, Kan S, Hao M, Jiang H, Li S, Li R, Wang Y, Wang D, Liu W
Heliyon 2024 Apr 30;10(8):e29291
Heliyon 2024 Apr 30;10(8):e29291
Targeting IDH1-Mutated Oligodendroglioma with Acid Ceramidase Inhibitors.
Muley H, Dowdy T, Zaibaq F, Karadimov G, Li A, Song H, Zhang M, Zhang W, Wong Z, Zhang L, Lita A, Larion M
bioRxiv : the preprint server for biology 2024 Apr 29;
bioRxiv : the preprint server for biology 2024 Apr 29;
Triptolide induces apoptosis and cytoprotective autophagy by ROS accumulation via directly targeting peroxiredoxin 2 in gastric cancer cells.
Chen P, Zhong X, Song Y, Zhong W, Wang S, Wang J, Huang P, Niu Y, Yang W, Ding Z, Luo Q, Yang C, Wang J, Zhang W
Cancer letters 2024 Apr 10;587:216622
Cancer letters 2024 Apr 10;587:216622
Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus.
Xu HZ, Chen FX, Li K, Zhang Q, Han N, Li TF, Xu YH, Chen Y, Chen X
Drug delivery and translational research 2024 Apr 10;
Drug delivery and translational research 2024 Apr 10;
The developmental regulator HAND1 inhibits gastric carcinogenesis through enhancing ER stress apoptosis via targeting CHOP and BAK which is augmented by cisplatin.
Kuang Y, He Z, Li L, Wang C, Cheng X, Shi Q, Fu G, Ying J, Tao Q, Hu X
International journal of biological sciences 2023;19(1):120-136
International journal of biological sciences 2023;19(1):120-136
Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response.
Ma W, Zhang X, Zhuang L
Clinical, cosmetic and investigational dermatology 2023;16:1641-1651
Clinical, cosmetic and investigational dermatology 2023;16:1641-1651
HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress-driven hepatocellular carcinoma progression.
He L, Li H, Li C, Liu ZK, Lu M, Zhang RY, Wu D, Wei D, Shao J, Liu M, Wei HL, Zhang C, Wang Z, Kong LM, Chen ZN, Bian H
Cancer communications (London, England) 2023 Sep;43(9):981-1002
Cancer communications (London, England) 2023 Sep;43(9):981-1002
Deubiquitinase USP19 modulates apoptotic calcium release and endoplasmic reticulum stress by deubiquitinating BAG6 in triple negative breast cancer.
Zhang X, Chen X, Qian F, Zhu Y, He G, Yang J, Wu X, Zhang H, Yu X, Liu X
Clinical and translational medicine 2023 Sep;13(9):e1398
Clinical and translational medicine 2023 Sep;13(9):e1398
Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.
Xia B, Li Q, Zheng K, Wu J, Huang C, Liu K, You Q, Yuan X
European journal of pharmacology 2023 Sep 5;954:175864
European journal of pharmacology 2023 Sep 5;954:175864
ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer.
Farmaki E, Nath A, Emond R, Karimi KL, Grolmusz VK, Cosgrove PA, Bild AH
eLife 2023 Sep 29;12
eLife 2023 Sep 29;12
The UFMylated ribosome-recognition protein SAYSD1 is predominantly expressed in spermatids but is dispensable for fertility in mice.
Chang L, Fujii W, Yogo K
Biochemical and biophysical research communications 2023 Sep 24;674:102-108
Biochemical and biophysical research communications 2023 Sep 24;674:102-108
Panobinostat (LBH589) combined with AM1241 induces cervical cancer cell apoptosis through autophagy pathway.
Sheng B, Wang W, Xia D, Qu X
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
BMC pharmacology & toxicology 2023 Sep 22;24(1):45
Bavachin induces liver injury and cell apoptosis by targeting Wnt/β-catenin/DRP1 signaling pathway mediated mitochondrial dysfunction.
Yang Y, Zhou W, Wang Y, Ge Y, Fan Z, Liu Q, Gao Y
Toxicology letters 2023 Sep 15;387:1-13
Toxicology letters 2023 Sep 15;387:1-13
A selective ER-phagy exerts neuroprotective effects via modulation of α-synuclein clearance in parkinsonian models.
Kim DY, Shin JY, Lee JE, Kim HN, Chung SJ, Yoo HS, Kim SJ, Cho HJ, Lee EJ, Nam SJ, Kim SH, Jang J, Lee SE, Lee PH
Proceedings of the National Academy of Sciences of the United States of America 2023 Sep 12;120(37):e2221929120
Proceedings of the National Academy of Sciences of the United States of America 2023 Sep 12;120(37):e2221929120
Stress response mechanisms in protein misfolding diseases: Profiling a cellular model of Huntington's disease.
Almeida LM, Oliveira Â, Oliveira JMA, Pinho BR
Archives of biochemistry and biophysics 2023 Sep 1;745:109711
Archives of biochemistry and biophysics 2023 Sep 1;745:109711
Diosmetin-7-O-β-D-glucopyranoside suppresses endothelial-mesenchymal transformation through endoplasmic reticulum stress in cardiac fibrosis.
Wang H, Zhang X, Liu Y, Zhang Y, Wang Y, Peng Y, Ding Y
Clinical and experimental pharmacology & physiology 2023 Oct;50(10):789-805
Clinical and experimental pharmacology & physiology 2023 Oct;50(10):789-805
Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma.
Fan R, Wang S, Wu Y, Feng Y, Gao M, Cao Y, Ma X, Xie S, Wang C, Gao L, Wang Y, Dai F
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Phytotherapy research : PTR 2023 Oct;37(10):4655-4673
Narirutin ameliorates alcohol-induced liver injury by targeting MAPK14 in zebrafish larvae.
Park KH, Makki HMM, Kim SH, Chung HJ, Jung J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115350
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115350
Caffeic acid's role in mitigating polycystic ovary syndrome by countering apoptosis and ER stress triggered by oxidative stress.
Chiang YF, Lin IC, Huang KC, Chen HY, Ali M, Huang YJ, Hsia SM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115327
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115327
Undesirable ER stress induced by bavachin contributed to follicular atresia in zebrafish ovary.
Huang CS, Deng HF, Zhou L, Shen P, Ni YH, Wang NN, Li GF, Yue LX, Zhou YQ, Zhou W, Gao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115322
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115322
Knockdown of NR3C1 inhibits the proliferation and migration of clear cell renal cell carcinoma through activating endoplasmic reticulum stress-mitophagy.
Yan M, Wang J, Wang H, Zhou J, Qi H, Naji Y, Zhao L, Tang Y, Dai Y
Journal of translational medicine 2023 Oct 8;21(1):701
Journal of translational medicine 2023 Oct 8;21(1):701
A beneficial adaptive role for CHOP in driving cell fate selection during ER stress.
Liu K, Zhao C, Adajar RC, DeZwaan-McCabe D, Rutkowski DT
bioRxiv : the preprint server for biology 2023 Oct 23;
bioRxiv : the preprint server for biology 2023 Oct 23;
Mitochondrial DNA breaks activate an integrated stress response to reestablish homeostasis.
Fu Y, Sacco O, DeBitetto E, Kanshin E, Ueberheide B, Sfeir A
Molecular cell 2023 Oct 19;83(20):3740-3753.e9
Molecular cell 2023 Oct 19;83(20):3740-3753.e9
IKVAV peptide-containing hydrogel decreases fibrous scar after spinal cord injury by inhibiting fibroblast migration and activation.
Jiang T, Li S, Xu B, Liu K, Qiu T, Dai H
Behavioural brain research 2023 Oct 18;455:114683
Behavioural brain research 2023 Oct 18;455:114683
Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.
Qiu C, Shen X, Lu H, Chen Y, Xu C, Zheng P, Xia Y, Wang J, Zhang Y, Li S, Zou P, Cui R, Chen J
Cell death discovery 2023 Oct 13;9(1):375
Cell death discovery 2023 Oct 13;9(1):375
Metformin combined with glucose starvation synergistically suppress triple-negative breast cancer by enhanced unfolded protein response.
Li Y, Zhang Q, Yang J, He W, Jiang Y, Chen Y, Wang Y
Biochemical and biophysical research communications 2023 Oct 1;675:146-154
Biochemical and biophysical research communications 2023 Oct 1;675:146-154
3-Acetyldeoxynivalenol induces apoptosis, barrier dysfunction and endoplasmic reticulum stress by inhibiting mTORC1-dependent autophagy in porcine enterocytes.
Zhang T, Bai J, Chen G, Chen Z, Zeng S, Yang Y, Wu Z
Chemico-biological interactions 2023 Oct 1;384:110695
Chemico-biological interactions 2023 Oct 1;384:110695
Role of SIRT2 in intestinal barrier under cold exposure.
Guo J, Xu J, Chen L, Chen Z, Hu H, Nie J, Yuan J, Ma L, Lu J, Ji H, Xu B
Life sciences 2023 Oct 1;330:121949
Life sciences 2023 Oct 1;330:121949
Key Subdomains of Cerebral Dopamine Neurotrophic Factor Regulate Its Protective Function in 6-Hydroxydopamine-Lesioned PC12 Cells.
Liu H, Dong H, Wang C, Jia W, Wang G, Wang H, Zhong L, Gong L
DNA and cell biology 2023 Nov;42(11):680-688
DNA and cell biology 2023 Nov;42(11):680-688
Ascomylactam C Induces an Immunogenic Cell Death Signature via Mitochondria-Associated ER Stress in Lung Cancer and Melanoma.
Huang Y, Yan H, Zhang B, Zhu G, Yu J, Xiao X, He W, Chen Y, Gao X, She Z, Li M, Yuan J
Marine drugs 2023 Nov 21;21(12)
Marine drugs 2023 Nov 21;21(12)
Mannose-doped metal-organic frameworks induce tumor cell pyroptosis via the PERK pathway.
Jin N, Wang B, Liu X, Yin C, Li X, Wang Z, Chen X, Liu Y, Bu W, Sun H
Journal of nanobiotechnology 2023 Nov 15;21(1):426
Journal of nanobiotechnology 2023 Nov 15;21(1):426
Systemic deuteration of SCID mice using the water-isotopologue deuterium oxide (D(2) O) inhibits tumor growth in an orthotopic bioluminescent model of human pancreatic ductal adenocarcinoma.
Jandova J, Galons JP, Dettman DL, Wondrak GT
Molecular carcinogenesis 2023 May;62(5):598-612
Molecular carcinogenesis 2023 May;62(5):598-612
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
Hou XX, Li YW, Song JL, Zhang W, Liu R, Yuan H, Feng TT, Jiang ZY, Li WT, Zhu CL
World journal of gastroenterology 2023 May 7;29(17):2616-2627
World journal of gastroenterology 2023 May 7;29(17):2616-2627
FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis.
Wu J, Subbaiah KCV, Hedaya O, Chen S, Munger J, Tang WHW, Yan C, Yao P
bioRxiv : the preprint server for biology 2023 May 22;
bioRxiv : the preprint server for biology 2023 May 22;
Role of Protein Tyrosine Phosphatase 1B Inhibitor in Early Brain Injury of Subarachnoid Hemorrhage in Mice.
Zhang ZH, Zhou XM, Zhang X
Brain sciences 2023 May 18;13(5)
Brain sciences 2023 May 18;13(5)
Vitamin D receptor attenuate ischemia-reperfusion kidney injury via inhibiting ATF4.
Tang S, Wu X, Dai Q, Li Z, Yang S, Liu Y, Yi B, Wang J, Liao Q, Zhang W, Zhang H
Cell death discovery 2023 May 12;9(1):158
Cell death discovery 2023 May 12;9(1):158
Thioredoxin 1 overexpression attenuated diabetes-induced endoplasmic reticulum stress in Müller cells via apoptosis signal-regulating kinase 1.
Yu X, Teng Q, Bao K, Chudhary M, Qi H, Zhou W, Che H, Liu J, Ren X, Kong L
Journal of cellular biochemistry 2023 Mar;124(3):421-433
Journal of cellular biochemistry 2023 Mar;124(3):421-433
JQ-1/bortezomib combination strongly impairs MM and PEL survival by inhibiting c-Myc and mTOR despite the activation of prosurvival mechanisms.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Experimental hematology 2023 Mar-Apr;119-120:28-41
Experimental hematology 2023 Mar-Apr;119-120:28-41
RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy.
Chen J, Lei C, Zhang H, Huang X, Yang Y, Liu J, Jia Y, Shi H, Zhang Y, Zhang J, Du J
BMC molecular and cell biology 2023 Mar 3;24(1):7
BMC molecular and cell biology 2023 Mar 3;24(1):7
Atorvastatin prevents endoplasmic reticulum stress-mediated apoptosis via the Nrf2/HO-1 signaling pathway in TBI mice.
Feng Y, Lang J, Sun B, Yan Z, Zhao Z, Sun G
Neurological research 2023 Jun;45(6):590-602
Neurological research 2023 Jun;45(6):590-602
Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation.
Chen G, Tang Q, Yu S, Shen Y, Sun J, Peng J, Yin Y, Feng G, Lu X, Mei G, Zhang Y, Wan Q, Zhang L, Chen L
Cell death and differentiation 2023 Jun;30(6):1503-1516
Cell death and differentiation 2023 Jun;30(6):1503-1516
Scalp acupuncture alleviates cerebral ischemic stroke-induced motor dysfunction in rats via regulating endoplasmic reticulum stress and ER-phagy.
Zhang Y, Lou H, Lu J, Tang X, Pang T, Lei S, Cong D, Wang Y, Sun L
Scientific reports 2023 Jun 21;13(1):10119
Scientific reports 2023 Jun 21;13(1):10119
[Cordycepin, a metabolite of Cordyceps militaris, inhibits xenograft tumor growth of tongue squamous cell carcinoma in nude mice].
Zheng Q, Shao Y, Zheng W, Zou Y
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):873-878
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jun 20;43(6):873-878
Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer.
Zhou F, Gao H, Shang L, Li J, Zhang M, Wang S, Li R, Ye L, Yang S
Journal of experimental & clinical cancer research : CR 2023 Jun 19;42(1):150
Journal of experimental & clinical cancer research : CR 2023 Jun 19;42(1):150
Ginsenoside Rg1 regulates autophagy and endoplasmic reticulum stress via the AMPK/mTOR and PERK/ATF4/CHOP pathways to alleviate alcohol‑induced myocardial injury.
Tian G, Li J, Zhou L
International journal of molecular medicine 2023 Jul;52(1)
International journal of molecular medicine 2023 Jul;52(1)
Bavachin protects against diet-induced hepatic steatosis and obesity in mice.
Wei X, Lin L, Yuan QQ, Wang XY, Zhang Q, Zhang XM, Tang KC, Guo MY, Dong TY, Han W, Huang DK, Qi YL, Zhang M, Zhang HB
Acta pharmacologica Sinica 2023 Jul;44(7):1416-1428
Acta pharmacologica Sinica 2023 Jul;44(7):1416-1428
Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice.
Wu J, Li J, Wu Y, Yang M, Chen Y, Wang N, Wang J, Yuan Z, Yi J, Yang C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113811
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jul;177:113811
Coffee prevents IQ-induced liver damage by regulating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and the MAPK/NF-κB signaling pathway in zebrafish.
Li D, Li Z, Dong L, Zhang Y, Lu Y, Wang J, Sun H, Wang S
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Food research international (Ottawa, Ont.) 2023 Jul;169:112946
Xylanase improves the intestinal barrier function of Nile tilapia (Oreochromis niloticus) fed with soybean (Glycine max) meal.
Wang T, Zhou N, He J, Hao Z, Zhou C, Du Y, Du Z, Su X, Zhang M
Journal of animal science and biotechnology 2023 Jul 7;14(1):86
Journal of animal science and biotechnology 2023 Jul 7;14(1):86
Identification of EGF Receptor and Thrombospondin-1 as Endogenous Targets of ER-Associated Degradation Enhancer EDEM1 in HeLa Cells.
Miura K, Katsuki R, Yoshida S, Ohta R, Tamura T
International journal of molecular sciences 2023 Jul 29;24(15)
International journal of molecular sciences 2023 Jul 29;24(15)
Nobiletin inhibits de novo FA synthesis to alleviate gastric cancer progression by regulating endoplasmic reticulum stress.
Chen M, Zhang R, Chen Y, Chen X, Li Y, Shen J, Yuan M, Chen Y, Wu J, Sun Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154902
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154902
Glutamine supplementation reverses manganese neurotoxicity by eliciting the mitochondrial unfolded protein response.
Zhang S, Zhang J, Wu L, Chen L, Niu P, Li J
iScience 2023 Jul 21;26(7):107136
iScience 2023 Jul 21;26(7):107136
Identification of genomic binding sites and direct target genes for the transcription factor DDIT3/CHOP.
Osman A, Lindén M, Österlund T, Vannas C, Andersson L, Escobar M, Ståhlberg A, Åman P
Experimental cell research 2023 Jan 1;422(1):113418
Experimental cell research 2023 Jan 1;422(1):113418
Silica nanoparticles aggravated the metabolic associated fatty liver disease through disturbed amino acid and lipid metabolisms-mediated oxidative stress.
Abulikemu A, Zhao X, Xu H, Li Y, Ma R, Yao Q, Wang J, Sun Z, Li Y, Guo C
Redox biology 2023 Feb;59:102569
Redox biology 2023 Feb;59:102569
The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress.
Li Y, She W, Guo T, Huang T, Liu Y, Liu P, Xu X, Wang X, Wang M, Yu C, Liu Y, Wei Y
Biochemical pharmacology 2023 Feb;208:115404
Biochemical pharmacology 2023 Feb;208:115404
Chlorin e6-induced photodynamic effect facilitates immunogenic cell death of lung cancer as a result of oxidative endoplasmic reticulum stress and DNA damage.
Yu TT, Hu J, Li QR, Peng XC, Xu HZ, Han N, Li LG, Yang XX, Xu X, Yang ZY, Chen H, Chen X, Wang MF, Li TF
International immunopharmacology 2023 Feb;115:109661
International immunopharmacology 2023 Feb;115:109661
Non-Lethal Concentrations of CdCl(2) Cause Marked Alternations in Cellular Stress Responses within Exposed Sertoli Cell Line.
Man Y, Liu Y, Xiong C, Zhang Y, Zhang L
Toxics 2023 Feb 9;11(2)
Toxics 2023 Feb 9;11(2)
Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes.
Shah A, Huck I, Duncan K, Gansemer ER, Apte U, Stamnes MA, Rutkowski DT
bioRxiv : the preprint server for biology 2023 Feb 9;
bioRxiv : the preprint server for biology 2023 Feb 9;
Probiotic-Functionalized Silk Fibroin/Sodium Alginate Scaffolds with Endoplasmic Reticulum Stress-Relieving Properties for Promoted Scarless Wound Healing.
Dou Z, Li B, Wu L, Qiu T, Wang X, Zhang X, Shen Y, Lu M, Yang Y
ACS applied materials & interfaces 2023 Feb 8;15(5):6297-6311
ACS applied materials & interfaces 2023 Feb 8;15(5):6297-6311
Young and undamaged recombinant albumin alleviates T2DM by improving hepatic glycolysis through EGFR and protecting islet β cells in mice.
Liu H, Ju A, Dong X, Luo Z, Tang J, Ma B, Fu Y, Luo Y
Journal of translational medicine 2023 Feb 6;21(1):89
Journal of translational medicine 2023 Feb 6;21(1):89
Stress granules inhibit endoplasmic reticulum stress-mediated apoptosis during hypoxia-induced injury in acute liver failure.
Li WY, Yang F, Li X, Wang LW, Wang Y
World journal of gastroenterology 2023 Feb 28;29(8):1315-1329
World journal of gastroenterology 2023 Feb 28;29(8):1315-1329
NRF2 and Bip Interconnection Mediates Resistance to the Organometallic Ruthenium-Cymene Bisdemethoxycurcumin Complex Cytotoxicity in Colon Cancer Cells.
Garufi A, Pettinari R, Marchetti F, Cirone M, D'Orazi G
Biomedicines 2023 Feb 16;11(2)
Biomedicines 2023 Feb 16;11(2)
Apelin-13 alleviates contrast-induced acute kidney injury by inhibiting endoplasmic reticulum stress.
Liu Q, Duan SB, Wang L, Luo XQ, Wang HS, Deng YH, Wu X, Wu T, Yan And P, Kang YX
Renal failure 2023 Dec;45(1):2179852
Renal failure 2023 Dec;45(1):2179852
Lithium chloride induces apoptosis by activating endoplasmic reticulum stress in pancreatic cancer.
Wu H, Zhang Y, Liang J, Wu J, Zhang Y, Su H, Zhang Q, Shen Y, Shen S, Wang L, Zou X, Hang C, Zhang S, Lv Y
Translational oncology 2023 Dec;38:101792
Translational oncology 2023 Dec;38:101792
The synthetic oleanane triterpenoid CDDO-2P-Im binds GRP78/BiP to induce unfolded protein response-mediated apoptosis in myeloma.
Luo G, Aldridge K, Chen T, Aslot V, Kim BG, Han EH, Singh N, Li S, Xiao TS, Sporn MB, Letterio JJ
Molecular oncology 2023 Dec;17(12):2526-2545
Molecular oncology 2023 Dec;17(12):2526-2545
Melatonin Offers Dual-Phase Protection to Brain Vessel Endothelial Cells in Prolonged Cerebral Ischemia-Recanalization Through Ameliorating ER Stress and Resolving Refractory Stress Granule.
Lu D, Liu Y, Huang H, Hu M, Li T, Wang S, Shen S, Wu R, Cai W, Lu T, Lu Z
Translational stroke research 2023 Dec;14(6):910-928
Translational stroke research 2023 Dec;14(6):910-928
Exogenous H(2) S promotes ubiquitin-mediated degradation of SREBP1 to alleviate diabetic cardiomyopathy via SYVN1 S-sulfhydration.
Zhang S, Wang M, Li H, Li Q, Liu N, Dong S, Zhao Y, Pang K, Huang J, Ren C, Wang Y, Tian Z, Lu F, Zhang W
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Journal of cachexia, sarcopenia and muscle 2023 Dec;14(6):2719-2732
Betaine ameliorates heat stress-induced apoptosis by affecting oxidative and endoplasmic reticulum stress in mouse Leydig cells.
Xiong Y, Li B, Wang K, Li J, He S
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):53-62
Bioscience, biotechnology, and biochemistry 2023 Dec 19;88(1):53-62
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma.
Patil SV, Kaipa BR, Ranshing S, Sundaresan Y, Millar JC, Nagarajan B, Kiehlbauch C, Zhang Q, Jain A, Searby CC, Scheetz TE, Clark AF, Sheffield VC, Zode GS
Research square 2023 Dec 19;
Research square 2023 Dec 19;
ER Stress-Perturbed Intracellular Protein O-GlcNAcylation Aggravates Podocyte Injury in Diabetes Nephropathy.
Song S, Hu T, Shi X, Jin Y, Liu S, Li X, Zou W, Wang C
International journal of molecular sciences 2023 Dec 18;24(24)
International journal of molecular sciences 2023 Dec 18;24(24)
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis.
Zou B, Zhang S, Zhao J, Song G, Weng F, Xu X, Li F, Jin J, Yan D, Huang K, Liu C, Li Y, Qiu F
European journal of pharmacology 2023 Dec 15;961:176193
European journal of pharmacology 2023 Dec 15;961:176193
Reduced Proteolipid Protein 2 promotes endoplasmic reticulum stress-related apoptosis and increases drug sensitivity in acute myeloid leukemia.
Xie F, Qu J, Lin D, Feng K, Tan M, Liao H, Zeng L, Xiong Q, Huang J, Chen W
Molecular biology reports 2023 Dec 12;51(1):10
Molecular biology reports 2023 Dec 12;51(1):10
XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells.
Cui Z, Qin R, Feng J, Liu Y, Zhou X, Qin X, Li Y, Zhang Z, He X
Tissue & cell 2023 Aug;83:102139
Tissue & cell 2023 Aug;83:102139
Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner.
Huang S, Zhang NQ, Xu CJ, Huang WQ, Li DX, Li J, Yao LL, Sundquist K, Sundquist J, Jiang SH, Xing X, Hu LP, Zhang ZG, Ji J, Zhang XL
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):953-967
Cellular oncology (Dordrecht, Netherlands) 2023 Aug;46(4):953-967
Tanshinone IIA ameliorates experimental diabetic cardiomyopathy by inhibiting endoplasmic reticulum stress in cardiomyocytes via SIRT1.
Wu S, Lu D, Gajendran B, Hu Q, Zhang J, Wang S, Han M, Xu Y, Shen X
Phytotherapy research : PTR 2023 Aug;37(8):3543-3558
Phytotherapy research : PTR 2023 Aug;37(8):3543-3558
VPS34-IN1 induces apoptosis of ER+ breast cancer cells via activating PERK/ATF4/CHOP pathway.
Wu Q, Zhou D, Shen Z, Chen B, Wang G, Wu L, Zhang L, Li X, Yuan L, Wu Y, Qu N, Zhou W
Biochemical pharmacology 2023 Aug;214:115634
Biochemical pharmacology 2023 Aug;214:115634
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Liu Z, Nan P, Gong Y, Tian L, Zheng Y, Wu Z
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114897
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114897
Zinc deficiency causes oxidative stress, endoplasmic reticulum stress, apoptosis and inflammation in hepatocytes in grass carp.
Cui J, Xu T, Lv H, Guo MY
Fish & shellfish immunology 2023 Aug;139:108905
Fish & shellfish immunology 2023 Aug;139:108905
SQLE promotes pancreatic cancer growth by attenuating ER stress and activating lipid rafts-regulated Src/PI3K/Akt signaling pathway.
Xu R, Song J, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Cell death & disease 2023 Aug 4;14(8):497
Cell death & disease 2023 Aug 4;14(8):497
Advanced oxidation protein products induce Paneth cells defects by endoplasmic reticulum stress in Crohn's disease.
Shi J, Wang W, Sun S, Xu X, Fei J, Zhou Q, Qin C, Ou S, Wu F, Wu FT, Xu T, Bai L, Xie F
iScience 2023 Aug 18;26(8):107312
iScience 2023 Aug 18;26(8):107312
Rosmarinic acid alleviates intestinal inflammatory damage and inhibits endoplasmic reticulum stress and smooth muscle contraction abnormalities in intestinal tissues by regulating gut microbiota.
Li K, Wu J, Xu S, Li X, Zhang Y, Gao XJ
Microbiology spectrum 2023 Aug 18;11(5):e0191423
Microbiology spectrum 2023 Aug 18;11(5):e0191423
cFLIP(L) Alleviates Myocardial Ischemia-Reperfusion Injury by Inhibiting Endoplasmic Reticulum Stress.
Li YZ, Wu H, Liu D, Yang J, Yang J, Ding JW, Zhou G, Zhang J, Zhang D
Cardiovascular drugs and therapy 2023 Apr;37(2):225-238
Cardiovascular drugs and therapy 2023 Apr;37(2):225-238
Hydrogen sulfide regulates SERCA2a SUMOylation by S-Sulfhydration of SENP1 to ameliorate cardiac systole-diastole function in diabetic cardiomyopathy.
Peng S, Wang M, Zhang S, Liu N, Li Q, Kang J, Chen L, Li M, Pang K, Huang J, Lu F, Zhao D, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114200
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Apr;160:114200
Dihydroartemisinin elicits immunogenic death through ferroptosis-triggered ER stress and DNA damage for lung cancer immunotherapy.
Han N, Yang ZY, Xie ZX, Xu HZ, Yu TT, Li QR, Li LG, Peng XC, Yang XX, Hu J, Xu X, Chen X, Wang MF, Li TF
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154682
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Apr;112:154682
Apurinic/apyrimidinic endonuclease 1 regulates palmitic acid-mediated apoptosis in cardiomyocytes via endoplasmic reticulum stress.
Fan J, Liu M, Li X, Gao S, Wang Y, Li A, Chen L, Zhou D, Chen H, Xu Z, Wu Z, Wu K
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Biochemical and biophysical research communications 2023 Apr 2;650:123-131
Antitumoral effects of Bortezomib in malignant mesothelioma: evidence of mild endoplasmic reticulum stress in vitro and activation of T cell response in vivo.
Benvenuto M, Angiolini V, Focaccetti C, Nardozi D, Palumbo C, Carrano R, Rufini A, Bei R, Miele MT, Mancini P, Barillari G, Cirone M, Ferretti E, Tundo GR, Mutti L, Masuelli L, Bei R
Biology direct 2023 Apr 17;18(1):17
Biology direct 2023 Apr 17;18(1):17
Citrinin Exposure Induced Testicular Damage and Spermatogenesis Disorder by Triggering Endoplasmic Reticulum Stress.
Wu J, Wu Y, Fan H, Yang C, Yang M, Kong X, Ning C, Wang S, Xiao W, Wang N, Yi J, Yuan Z
Foods (Basel, Switzerland) 2023 Apr 11;12(8)
Foods (Basel, Switzerland) 2023 Apr 11;12(8)
Benzo[a]pyrene induces epithelial tight junction disruption and apoptosis via inhibiting the initiation of autophagy in intestinal porcine epithelial cells.
Li J, Bai J, Si X, Jia H, Wu Z
Chemico-biological interactions 2023 Apr 1;374:110386
Chemico-biological interactions 2023 Apr 1;374:110386
Effects of folic acid on oxidative damage of kidney in lead-exposed rats.
Li N, Wen L, Yu Z, Li T, Wang T, Qiao M, Song L, Huang X
Frontiers in nutrition 2022;9:1035162
Frontiers in nutrition 2022;9:1035162
Qingfei Tongluo Formula Mitigates Mycoplasma pneumoniae Infection via the PERK Signaling Pathway.
Liu X, Wang M, Kan Q, Lin Y, Jiang Z
Disease markers 2022;2022:9340353
Disease markers 2022;2022:9340353
Bixin Prevents Colorectal Cancer Development through AMPK-Activated Endoplasmic Reticulum Stress.
Qiu Y, Li C, Zhang B
BioMed research international 2022;2022:9329151
BioMed research international 2022;2022:9329151
Naringenin Alleviates Renal Ischemia Reperfusion Injury by Suppressing ER Stress-Induced Pyroptosis and Apoptosis through Activating Nrf2/HO-1 Signaling Pathway.
Zhang B, Wan S, Liu H, Qiu Q, Chen H, Chen Z, Wang L, Liu X
Oxidative medicine and cellular longevity 2022;2022:5992436
Oxidative medicine and cellular longevity 2022;2022:5992436
LARS2 Regulates Apoptosis via ROS-Mediated Mitochondrial Dysfunction and Endoplasmic Reticulum Stress in Ovarian Granulosa Cells.
Feng S, Wan S, Liu S, Wang W, Tang M, Bai L, Zhu Y
Oxidative medicine and cellular longevity 2022;2022:5501346
Oxidative medicine and cellular longevity 2022;2022:5501346
Saikosaponin D Inducing Apoptosis and Autophagy through the Activation of Endoplasmic Reticulum Stress in Glioblastoma.
Liu G, Guan Y, Liu Y, Wang Y, Zhang J, Liu Y, Liu X
BioMed research international 2022;2022:5489553
BioMed research international 2022;2022:5489553
Upregulation of Glutaminyl Cyclase Contributes to ERS-Induced Apoptosis in PC12 Cells.
Shang Q, Yu X, Ouyang N, Xu P, Chen X, Wang Y, Li C, Wang X, Lu X, Xu C, Wu H
BioMed research international 2022;2022:4154697
BioMed research international 2022;2022:4154697
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis.
Hong Q, Zhang Y, Lin W, Wang W, Yuan Y, Lin J, Xie Z, Li X, Meng Y
Journal of immunology research 2022;2022:2291877
Journal of immunology research 2022;2022:2291877
Oleoylethanolamide Alleviates Hepatic Ischemia-Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress-Associated Apoptosis.
Qi S, Yan Q, Wang Z, Liu D, Zhan M, Du J, Chen L
PPAR research 2022;2022:2212996
PPAR research 2022;2022:2212996
Ursolic Acid Derivative UA232 Promotes Tumor Cell Apoptosis by Inducing Endoplasmic Reticulum Stress and Lysosomal Dysfunction.
Gou W, Luo N, Yu B, Wu H, Wu S, Tian C, Guo J, Ning H, Bi C, Wei H, Hou W, Li Y
International journal of biological sciences 2022;18(6):2639-2651
International journal of biological sciences 2022;18(6):2639-2651
Inhibition of the integrated stress response reverses oxidative stress damage-induced postoperative cognitive dysfunction.
Jiang L, Dong R, Xu M, Liu Y, Xu J, Ma Z, Xia T, Gu X
Frontiers in cellular neuroscience 2022;16:992869
Frontiers in cellular neuroscience 2022;16:992869
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Li Y, Li C, Xiong Y, Fang B, Lin X, Huang Q
Drug design, development and therapy 2022;16:1713-1729
Drug design, development and therapy 2022;16:1713-1729
Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress.
Wu Y, Meng W, Guan M, Zhao X, Zhang C, Fang Q, Zhang Y, Sun Z, Cai M, Huang D, Yang X, Yu Y, Cui Y, He S, Chai R
Frontiers in molecular neuroscience 2022;15:963083
Frontiers in molecular neuroscience 2022;15:963083
Nedd4-2 Haploinsufficiency in Mice Impairs the Ubiquitination of Rer1 and Increases the Susceptibility to Endoplasmic Reticulum Stress and Seizures.
Liu X, Zhang L, Zhang H, Liang X, Zhang B, Tu J, Zhao Y
Frontiers in molecular neuroscience 2022;15:919718
Frontiers in molecular neuroscience 2022;15:919718
Cryptotanshinone alleviates myocardial ischemia and reperfusion injury in rats to mitigate ER stress-dependent apoptosis by modulating the JAK1/STAT3 axis.
Wang S, Sun L, Zhu Z, Liu J, Ge W, Li B, Wang B
American journal of translational research 2022;14(7):5024-5039
American journal of translational research 2022;14(7):5024-5039
TM9SF4 Is a Crucial Regulator of Inflammation and ER Stress in Inflammatory Bowel Disease.
Xie M, Mak JWY, Yu H, Cheng CTY, Chan HCH, Chan TT, Lau LHS, Wong MTL, Ko WH, Jiang L, Yao X
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Cellular and molecular gastroenterology and hepatology 2022;14(2):245-270
Melatonin promotes sirtuin 1 expression and inhibits IRE1α-XBP1S-CHOP to reduce endoplasmic reticulum stress-mediated apoptosis in chondrocytes.
Qin K, Tang H, Ren Y, Yang D, Li Y, Huang W, Wu Y, Yin Z
Frontiers in pharmacology 2022;13:940629
Frontiers in pharmacology 2022;13:940629
Pinelliae rhizoma alleviated acute lung injury induced by lipopolysaccharide via suppressing endoplasmic reticulum stress-mediated NLRP3 inflammasome.
Wang NN, Zhang XX, Shen P, Huang CS, Deng HF, Zhou L, Yue LX, Shen BY, Zhou W, Gao Y
Frontiers in pharmacology 2022;13:883865
Frontiers in pharmacology 2022;13:883865
Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT.
Ni YH, Deng HF, Zhou L, Huang CS, Wang NN, Yue LX, Li GF, Yu HJ, Zhou W, Gao Y
Frontiers in pharmacology 2022;13:872474
Frontiers in pharmacology 2022;13:872474
Cold Exposure Induces Intestinal Barrier Damage and Endoplasmic Reticulum Stress in the Colon via the SIRT1/Nrf2 Signaling Pathway.
Guo J, Hu H, Chen Z, Xu J, Nie J, Lu J, Ma L, Ji H, Yuan J, Xu B
Frontiers in physiology 2022;13:822348
Frontiers in physiology 2022;13:822348
Fuzheng Nizeng Decoction regulated ferroptosis and endoplasmic reticulum stress in the treatment of gastric precancerous lesions: A mechanistic study based on metabolomics coupled with transcriptomics.
Chu YM, Wang TX, Jia XF, Yang Y, Shi ZM, Cui GH, Huang QY, Ye H, Zhang XZ
Frontiers in pharmacology 2022;13:1066244
Frontiers in pharmacology 2022;13:1066244
Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction.
Li W, Li M, Chen K, Tang Y, Yin R, Lan L, Hong G
Frontiers in pharmacology 2022;13:1029775
Frontiers in pharmacology 2022;13:1029775
FUS-DDIT3 Fusion Oncoprotein Expression Affects JAK-STAT Signaling in Myxoid Liposarcoma.
Dolatabadi S, Jonasson E, Andersson L, Luna Santamaría M, Lindén M, Österlund T, Åman P, Ståhlberg A
Frontiers in oncology 2022;12:816894
Frontiers in oncology 2022;12:816894
RRBP1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype.
Chen R, Wang Y, Xu Y, He Y, Li Q, Xia C, Zhang B
Frontiers in oncology 2022;12:1005152
Frontiers in oncology 2022;12:1005152
Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway.
Zhang L, Li C, Fu L, Yu Z, Xu G, Zhou J, Shen M, Feng Z, Zhu H, Xie T, Zhou L, Zhou X
PeerJ 2022;10:e12759
PeerJ 2022;10:e12759
Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis.
Sun S, Han Y, Zhang C, Liu H, Wang B, Cao S, Yuan Q, Wei S, Chen Y
Frontiers in cell and developmental biology 2022;10:827714
Frontiers in cell and developmental biology 2022;10:827714
HSPA5 repressed ferroptosis to promote colorectal cancer development by maintaining GPX4 stability.
Wang R, Hua L, Ma P, Song Y, Min J, Guo Y, Yang C, Li J, Su H
Neoplasma 2022 Sep;69(5):1054-1069
Neoplasma 2022 Sep;69(5):1054-1069
Identification of Ferroptotic Genes in Spinal Cord Injury at Different Time Points: Bioinformatics and Experimental Validation.
Kang Y, Li Q, Zhu R, Li S, Xu X, Shi X, Yin Z
Molecular neurobiology 2022 Sep;59(9):5766-5784
Molecular neurobiology 2022 Sep;59(9):5766-5784
Role of Mydgf in the regulation of hypoxia/reoxygenation-induced apoptosis in cardiac microvascular endothelial cells.
Wang Y, Zhang Y, Li J, Zhao R, Long X, Li C, Liu W, Chen W, Shi B
In vitro cellular & developmental biology. Animal 2022 Sep;58(8):669-678
In vitro cellular & developmental biology. Animal 2022 Sep;58(8):669-678
Acacetin antagonized lipotoxicity in pancreatic β-cells via ameliorating oxidative stress and endoplasmic reticulum stress.
Wang N, Gao Q, Shi J, Yulan C, Ji W, Sheng X, Zhang R
Molecular biology reports 2022 Sep;49(9):8727-8740
Molecular biology reports 2022 Sep;49(9):8727-8740
UFL1 alleviates ER stress and apoptosis stimulated by LPS via blocking the ferroptosis pathway in human granulosa-like cells.
Li J, Tang X, Tu X, Jin Z, Dong H, Yang Q, Yao T, Pan Z
Cell stress & chaperones 2022 Sep;27(5):485-497
Cell stress & chaperones 2022 Sep;27(5):485-497
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
Role of hair follicles in the pathogenesis of arsenical-induced cutaneous damage.
Srivastava RK, Wang Y, Khan J, Muzaffar S, Lee MB, Weng Z, Croutch C, Agarwal A, Deshane J, Athar M
Annals of the New York Academy of Sciences 2022 Sep;1515(1):168-183
Annals of the New York Academy of Sciences 2022 Sep;1515(1):168-183
Zearalenone Promotes LPS-Induced Oxidative Stress, Endoplasmic Reticulum Stress, and Accelerates Bovine Mammary Epithelial Cell Apoptosis.
Fu Y, Jin Y, Tian Y, Yu H, Wang R, Qi H, Feng B, Zhang J
International journal of molecular sciences 2022 Sep 18;23(18)
International journal of molecular sciences 2022 Sep 18;23(18)
Liproxstatin‑1 induces cell cycle arrest, apoptosis, and caspase‑3/GSDME‑dependent secondary pyroptosis in K562 cells.
Dong HQ, Liang SJ, Xu YL, Dai Y, Sun N, Deng DH, Cheng P
International journal of oncology 2022 Oct;61(4)
International journal of oncology 2022 Oct;61(4)
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Su H, Mei Y, Luo S, Wu H, He Y, Shiraishi Y, Hu P, Cohen RA, Tong X
British journal of pharmacology 2022 Oct;179(20):4778-4791
British journal of pharmacology 2022 Oct;179(20):4778-4791
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Sun H, Shen L, Zhang P, Lin F, Ma J, Wu Y, Yu H, Sun L
International journal of molecular sciences 2022 Oct 4;23(19)
International journal of molecular sciences 2022 Oct 4;23(19)
Pterostilbene Prevents Tunicamycin-Induced Intestinal Barrier Damage by Targeting Endoplasmic Reticulum Stress, Oxidative Stress, Autophagy, and Gut Microbiota.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Journal of agricultural and food chemistry 2022 Oct 26;70(42):13661-13675
Exploring the molecular mechanisms underlie the endoplasmic reticulum stress-mediated methylmercury-induced neuronal developmental damage.
Pan J, Li X, Liu H, Wang C, Xu S, Xu B, Deng Y, Yang T, Liu W
Ecotoxicology and environmental safety 2022 Oct 15;245:114099
Ecotoxicology and environmental safety 2022 Oct 15;245:114099
ER stress transforms random olfactory receptor choice into axon targeting precision.
Shayya HJ, Kahiapo JK, Duffié R, Lehmann KS, Bashkirova L, Monahan K, Dalton RP, Gao J, Jiao S, Schieren I, Belluscio L, Lomvardas S
Cell 2022 Oct 13;185(21):3896-3912.e22
Cell 2022 Oct 13;185(21):3896-3912.e22
A systems biological analysis of the ATF4-GADD34-CHOP regulatory triangle upon endoplasmic reticulum stress.
Márton M, Bánhegyi G, Gyöngyösi N, Kálmán EÉ, Pettkó-Szandtner A, Káldi K, Kapuy O
FEBS open bio 2022 Nov;12(11):2065-2082
FEBS open bio 2022 Nov;12(11):2065-2082
Pterostilbene attenuates intrauterine growth retardation-induced colon inflammation in piglets by modulating endoplasmic reticulum stress and autophagy.
Chen Y, Zhang H, Li Y, Ji S, Jia P, Wang T
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Journal of animal science and biotechnology 2022 Nov 4;13(1):125
Paxlovid accelerates cartilage degeneration and senescence through activating endoplasmic reticulum stress and interfering redox homeostasis.
Kong K, Chang Y, Qiao H, Zhao C, Chen X, Rong K, Zhang P, Jin M, Zhang J, Li H, Zhai Z
Journal of translational medicine 2022 Nov 26;20(1):549
Journal of translational medicine 2022 Nov 26;20(1):549
Hydrogen Sulfide Regulates SERCA2a Ubiquitylation via Muscle RING Finger-1 S-Sulfhydration to Affect Cardiac Contractility in db/db Mice.
Peng S, Zhao D, Li Q, Wang M, Zhang S, Pang K, Huang J, Lu F, Chen H, Zhang W
Cells 2022 Nov 2;11(21)
Cells 2022 Nov 2;11(21)
Manganese Mitigates Heat Stress-Induced Apoptosis by Alleviating Endoplasmic Reticulum Stress and Activating the NRF2/SOD2 Pathway in Primary Chick Embryonic Myocardial Cells.
Qin S, Wang R, Tang D, Qin S, Guo Y, Shi Z
Biological trace element research 2022 May;200(5):2312-2320
Biological trace element research 2022 May;200(5):2312-2320
Wolframin is a novel regulator of tau pathology and neurodegeneration.
Chen S, Acosta D, Li L, Liang J, Chang Y, Wang C, Fitzgerald J, Morrison C, Goulbourne CN, Nakano Y, Villegas NCH, Venkataraman L, Brown C, Serrano GE, Bell E, Wemlinger T, Wu M, Kokiko-Cochran ON, Popovich P, Flowers XE, Honig LS, Vonsattel JP, Scharre DW, Beach TG, Ma Q, Kuret J, Kõks S, Urano F, Duff KE, Fu H
Acta neuropathologica 2022 May;143(5):547-569
Acta neuropathologica 2022 May;143(5):547-569
Dihydroartemisinin alleviates steatosis and inflammation in nonalcoholic steatohepatitis by decreasing endoplasmic reticulum stress and oxidative stress.
Li T, Chen Y, Tan P, Shi H, Huang Z, Cai T, Cheng Y, Du Y, Fu W
Bioorganic chemistry 2022 May;122:105737
Bioorganic chemistry 2022 May;122:105737
The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma.
Zullow HJ, Sankar A, Ingram DR, Samé Guerra DD, D'Avino AR, Collings CK, Lazcano R, Wang WL, Liang Y, Qi J, Lazar AJ, Kadoch C
Molecular cell 2022 May 5;82(9):1737-1750.e8
Molecular cell 2022 May 5;82(9):1737-1750.e8
Ubiquitin-like modifier 1 ligating enzyme 1 relieves cisplatin-induced premature ovarian failure by reducing endoplasmic reticulum stress in granulosa cells.
Tang X, Dong H, Fang Z, Li J, Yang Q, Yao T, Pan Z
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):84
Reproductive biology and endocrinology : RB&E 2022 May 24;20(1):84
diTFPP, a Phenoxyphenol, Sensitizes Hepatocellular Carcinoma Cells to C(2)-Ceramide-Induced Autophagic Stress by Increasing Oxidative Stress and ER Stress Accompanied by LAMP2 Hypoglycosylation.
Chiu CC, Chen YC, Bow YD, Chen JY, Liu W, Huang JL, Shu ED, Teng YN, Wu CY, Chang WT
Cancers 2022 May 20;14(10)
Cancers 2022 May 20;14(10)
Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis.
Jiang B, Zhang J, Zhao G, Liu M, Hu J, Lin F, Wang J, Zhao W, Ma H, Zhang C, Wu C, Yao L, Liu Q, Chen X, Cao Y, Zheng Y, Zhang C, Han A, Lin D, Li Q
Molecular cell 2022 May 19;82(10):1821-1835.e6
Molecular cell 2022 May 19;82(10):1821-1835.e6
sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes.
Zhu L, Li B, Chen D, Chen N, Xu L, Li Q, Chen X
Life sciences 2022 May 1;296:120438
Life sciences 2022 May 1;296:120438
Attenuation of Activated eIF2α Signaling by ISRIB Treatment After Spinal Cord Injury Improves Locomotor Function.
Chang L, Liu X, Chen J, Liu H, Wang G, Wang G, Liao X, Shen X
Journal of molecular neuroscience : MN 2022 Mar;72(3):585-597
Journal of molecular neuroscience : MN 2022 Mar;72(3):585-597
Azithromycin alleviates the severity of rheumatoid arthritis by targeting the unfolded protein response component of glucose-regulated protein 78 (GRP78).
Zhang Y, Ge L, Song G, Zhang R, Li S, Shi H, Zhang H, Li Y, Pan J, Wang L, Han J
British journal of pharmacology 2022 Mar;179(6):1201-1219
British journal of pharmacology 2022 Mar;179(6):1201-1219
Fucoidan protects the pancreas and improves glucose metabolism through inhibiting inflammation and endoplasmic reticulum stress in T2DM rats.
Liu Y, Huang H, Xu Z, Xue Y, Zhang D, Zhang Y, Li W, Li X
Food & function 2022 Mar 7;13(5):2693-2709
Food & function 2022 Mar 7;13(5):2693-2709
Estrogen inhibits endoplasmic reticulum stress and ameliorates myocardial ischemia/reperfusion injury in rats by upregulating SERCA2a.
Chen J, Liu Y, Pan D, Xu T, Luo Y, Wu W, Wu P, Zhu H, Li D
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
Cell communication and signaling : CCS 2022 Mar 24;20(1):38
Targeting c-Myc Unbalances UPR towards Cell Death and Impairs DDR in Lymphoma and Multiple Myeloma Cells.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Biomedicines 2022 Mar 22;10(4)
Biomedicines 2022 Mar 22;10(4)
Pathogenic Role of Endoplasmic Reticulum Stress in Diabetic Corneal Endothelial Dysfunction.
Chen C, Zhang B, Xue J, Li Z, Dou S, Chen H, Wang Q, Qu M, Wang H, Zhang Y, Wan L, Zhou Q, Xie L
Investigative ophthalmology & visual science 2022 Mar 2;63(3):4
Investigative ophthalmology & visual science 2022 Mar 2;63(3):4
The Impact of NRF2 Inhibition on Drug-Induced Colon Cancer Cell Death and p53 Activity: A Pilot Study.
Garufi A, Pistritto G, D'Orazi V, Cirone M, D'Orazi G
Biomolecules 2022 Mar 17;12(3)
Biomolecules 2022 Mar 17;12(3)
Protective Effects of Taraxasterol against Deoxynivalenol-Induced Damage to Bovine Mammary Epithelial Cells.
Wang J, Zheng K, Jin Y, Fu Y, Wang R, Zhang J
Toxins 2022 Mar 15;14(3)
Toxins 2022 Mar 15;14(3)
Hesperadin suppresses pancreatic cancer through ATF4/GADD45A axis at nanomolar concentrations.
Zhang Y, Wu J, Fu Y, Yu R, Su H, Zheng Q, Wu H, Zhou S, Wang K, Zhao J, Shen S, Xu G, Wang L, Yan C, Zou X, Lv Y, Zhang S
Oncogene 2022 Jun;41(25):3394-3408
Oncogene 2022 Jun;41(25):3394-3408
FAdV-4 induce autophagy via the endoplasmic reticulum stress-related unfolded protein response.
Ma H, Ding Y, Du K, Chang K, Niu Y
Veterinary microbiology 2022 Jun;269:109388
Veterinary microbiology 2022 Jun;269:109388
Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis.
Hosoda K, Imahori T, Tanaka K, Uno T, Nakai T, Kohta M, Fujita A, Sasayama T
Translational stroke research 2022 Jun;13(3):420-431
Translational stroke research 2022 Jun;13(3):420-431
Quinoa Reduces High-Fat Diet-Induced Obesity in Mice via Potential Microbiota-Gut-Brain-Liver Interaction Mechanisms.
Wang TY, Tao SY, Wu YX, An T, Lv BH, Liu JX, Liu YT, Jiang GJ
Microbiology spectrum 2022 Jun 29;10(3):e0032922
Microbiology spectrum 2022 Jun 29;10(3):e0032922
ATF6 prevents DNA damage and cell death in colon cancer cells undergoing ER stress.
Benedetti R, Romeo MA, Arena A, Gilardini Montani MS, Di Renzo L, D'Orazi G, Cirone M
Cell death discovery 2022 Jun 25;8(1):295
Cell death discovery 2022 Jun 25;8(1):295
Intravenously transplanted mesenchymal stromal cells: a new endocrine reservoir for cardioprotection.
Huang A, Liu Y, Qi X, Chen S, Huang H, Zhang J, Han Z, Han ZC, Li Z
Stem cell research & therapy 2022 Jun 17;13(1):253
Stem cell research & therapy 2022 Jun 17;13(1):253
Inhibiting the IRE1α Axis of the Unfolded Protein Response Enhances the Antitumor Effect of AZD1775 in TP53 Mutant Ovarian Cancer.
Xiao R, You L, Zhang L, Guo X, Guo E, Zhao F, Yang B, Li X, Fu Y, Lu F, Wang Z, Liu C, Peng W, Li W, Yang X, Dou Y, Liu J, Wang W, Qin T, Cui Y, Zhang X, Li F, Jin Y, Zeng Q, Wang B, Mills GB, Chen G, Sheng X, Sun C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jul;9(21):e2105469
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jul;9(21):e2105469
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Wang J, Wang Q, Chen P, Li Q, Li Z, Xu M, Zeng K, Li C
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
Photodermatology, photoimmunology & photomedicine 2022 Jul;38(4):343-353
The impairment of DDR reduces XBP1s, further increasing DNA damage, and triggers autophagy via PERK/eIF2alpha in MM and IRE1alpha/JNK1/2 in PEL cells.
Arena A, Romeo MA, Benedetti R, Gilardini Montani MS, Cirone M
Biochemical and biophysical research communications 2022 Jul 12;613:19-25
Biochemical and biophysical research communications 2022 Jul 12;613:19-25
GBP5 promotes liver injury and inflammation by inducing hepatocyte apoptosis.
Ding K, Li X, Ren X, Ding N, Tao L, Dong X, Chen Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22119
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Jan;36(1):e22119
TRPV4 contributes to ER stress and inflammation: implications for Parkinson's disease.
Liu N, Bai L, Lu Z, Gu R, Zhao D, Yan F, Bai J
Journal of neuroinflammation 2022 Jan 29;19(1):26
Journal of neuroinflammation 2022 Jan 29;19(1):26
The Mitochondrial PHB2/OMA1/DELE1 Pathway Cooperates with Endoplasmic Reticulum Stress to Facilitate the Response to Chemotherapeutics in Ovarian Cancer.
Cheng M, Yu H, Kong Q, Wang B, Shen L, Dong D, Sun L
International journal of molecular sciences 2022 Jan 25;23(3)
International journal of molecular sciences 2022 Jan 25;23(3)
Nrf2 loss of function exacerbates endoplasmic reticulum stress-induced apoptosis in TBI mice.
Sun G, Zhao Z, Lang J, Sun B, Zhao Q
Neuroscience letters 2022 Jan 23;770:136400
Neuroscience letters 2022 Jan 23;770:136400
Zinc Supplementation Enhances the Pro-Death Function of UPR in Lymphoma Cells Exposed to Radiation.
Gonnella R, Guttieri L, Gilardini Montani MS, Santarelli R, Bassetti E, D'Orazi G, Cirone M
Biology 2022 Jan 13;11(1)
Biology 2022 Jan 13;11(1)
Nrf2 activation mediates the protection of mouse Sertoli Cells damage under acute heat stress conditions.
He C, Sun J, Yang D, He W, Wang J, Qin D, Zhang H, Cai H, Liu Y, Li N, Hua J, Peng S
Theriogenology 2022 Jan 1;177:183-194
Theriogenology 2022 Jan 1;177:183-194
Inhibition of the miR-193b-3p protects against oxidized low-density lipoprotein-induced HUVECs injury by upregulating ALDH2.
Bai Y, Wang M, Yang Y, Liu X, Chen Q, Guo Z
Cell biology international 2022 Feb;46(2):192-202
Cell biology international 2022 Feb;46(2):192-202
Involvement of increased endoplasmic reticulum stress in the development of cataracts in BALB.NCT-Cpox(nct) mice.
Liu C, Miyahara H, Dai J, Cui X, Li Y, Kang X, Higuchi K, Mori M
Experimental eye research 2022 Feb;215:108905
Experimental eye research 2022 Feb;215:108905
Zinc Protects against Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in TM3 Leydig Cells.
Xiong Y, Li J, He S
Biological trace element research 2022 Feb;200(2):728-739
Biological trace element research 2022 Feb;200(2):728-739
A missing piece of the puzzle in pulmonary fibrosis: anoikis resistance promotes fibroblast activation.
Yin J, Wang J, Zhang X, Liao Y, Luo W, Wang S, Ding J, Huang J, Chen M, Wang W, Fang S, Chao J
Cell & bioscience 2022 Feb 25;12(1):21
Cell & bioscience 2022 Feb 25;12(1):21
Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A.
Huang Y, Chen S, Pang L, Feng Z, Su H, Zhu W, Wei J
European journal of pharmacology 2022 Feb 15;917:174749
European journal of pharmacology 2022 Feb 15;917:174749
ATP6V1H deficiency impairs glucose tolerance by augmenting endoplasmic reticulum stress in high fat diet fed mice.
Yang S, Hou Y, Zhang H, Hao Y, Zhang Y, Zhao Z, Ruan W, Duan X
Archives of biochemistry and biophysics 2022 Feb 15;716:109116
Archives of biochemistry and biophysics 2022 Feb 15;716:109116
Pt(II)-NHC Complex Induces ROS-ERS-Related DAMP Balance to Harness Immunogenic Cell Death in Hepatocellular Carcinoma.
Bian M, Fan R, Yang Z, Chen Y, Xu Z, Lu Y, Liu W
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Journal of medicinal chemistry 2022 Feb 10;65(3):1848-1866
Jolkinolide B sensitizes bladder cancer to mTOR inhibitors via dual inhibition of Akt signaling and autophagy.
Sang J, Gan L, Zou MF, Lin ZJ, Fan RZ, Huang JL, Li W, Tang GH, Yin S
Cancer letters 2022 Feb 1;526:352-362
Cancer letters 2022 Feb 1;526:352-362
Endoplasmic reticulum stress mediates parathyroid hormone-induced apoptosis in vascular smooth muscle cells.
Duan S, Chen X, Liu Y, Guo W, Liu W
Renal failure 2022 Dec;44(1):126-136
Renal failure 2022 Dec;44(1):126-136
The Mechano-Ubiquitinome of Articular Cartilage: Differential Ubiquitination and Activation of a Group of ER-Associated DUBs and ER Stress Regulators.
Kaokhum N, Pinto-Fernández A, Wilkinson M, Kessler BM, Ismail HM
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100419
Molecular & cellular proteomics : MCP 2022 Dec;21(12):100419
Exosome modification to better alleviates endoplasmic reticulum stress induced chondrocyte apoptosis and osteoarthritis.
Wang Y, Fan A, Lu L, Pan Z, Ma M, Luo S, Liu Z, Yang L, Cai J, Yin F
Biochemical pharmacology 2022 Dec;206:115343
Biochemical pharmacology 2022 Dec;206:115343
Tetrandrine alleviates inflammation and neuron apoptosis in experimental traumatic brain injury by regulating the IRE1α/JNK/CHOP signal pathway.
Liu H, He S, Li C, Wang J, Zou Q, Liao Y, Chen R
Brain and behavior 2022 Dec;12(12):e2786
Brain and behavior 2022 Dec;12(12):e2786
Knockdown of TMEM160 leads to an increase in reactive oxygen species generation and the induction of the mitochondrial unfolded protein response.
Yamashita K, Haraguchi M, Yano M
FEBS open bio 2022 Dec;12(12):2179-2190
FEBS open bio 2022 Dec;12(12):2179-2190
Effects of natural 24-epibrassinolide on inducing apoptosis and restricting metabolism in hepatocarcinoma cells.
Zhou H, Zhuang W, Huang H, Ma N, Lei J, Jin G, Wu S, Zhou S, Zhao X, Lan L, Xia H, Shangguan F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154428
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154428
Deficiency of CFB attenuates renal tubulointerstitial damage by inhibiting ceramide synthesis in diabetic kidney disease.
Sun ZJ, Chang DY, Chen M, Zhao MH
JCI insight 2022 Dec 22;7(24)
JCI insight 2022 Dec 22;7(24)
African Swine Fever Virus MGF110-7L Induces Host Cell Translation Suppression and Stress Granule Formation by Activating the PERK/PKR-eIF2α Pathway.
Zhong H, Fan S, Du Y, Zhang Y, Zhang A, Jiang D, Han S, Wan B, Zhang G
Microbiology spectrum 2022 Dec 21;10(6):e0328222
Microbiology spectrum 2022 Dec 21;10(6):e0328222
Diverse injury responses of human oligodendrocyte to mediators implicated in multiple sclerosis.
Pernin F, Luo JXX, Cui QL, Blain M, Fernandes MGF, Yaqubi M, Srour M, Hall J, Dudley R, Jamann H, Larochelle C, Zandee SEJ, Prat A, Stratton JA, Kennedy TE, Antel JP
Brain : a journal of neurology 2022 Dec 19;145(12):4320-4333
Brain : a journal of neurology 2022 Dec 19;145(12):4320-4333
Endosomal lipid signaling reshapes the endoplasmic reticulum to control mitochondrial function.
Jang W, Puchkov D, Samsó P, Liang Y, Nadler-Holly M, Sigrist SJ, Kintscher U, Liu F, Mamchaoui K, Mouly V, Haucke V
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Science (New York, N.Y.) 2022 Dec 16;378(6625):eabq5209
Role of Ero1α in cognitive impairment induced by chronic hypoxia.
Zhang N, Shentu Y, Zhu M, Wang H, Yin X, Du C, Xue F, Fan J, Gong Y, Fan X
Brain research 2022 Dec 15;1797:148117
Brain research 2022 Dec 15;1797:148117
The IRE1/JNK signaling pathway regulates inflammation cytokines and production of glomerular extracellular matrix in the acute kidney injury to chronic kidney disease transition.
Liang Y, Qu L, Liu Z, Liang L, Wang Y, Quan S, Wang Y, Tang L
Molecular biology reports 2022 Aug;49(8):7709-7718
Molecular biology reports 2022 Aug;49(8):7709-7718
Sodium selenite attenuates zearalenone-induced apoptosis through inhibition of endoplasmic reticulum stress in goat trophoblast cells.
Xiong Y, Li B, Li J, Jin E, He S
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2022 Aug;35(4):699-710
Diterpenoid Vinigrol specifically activates ATF4/DDIT3-mediated PERK arm of unfolded protein response to drive non-apoptotic death of breast cancer cells.
Wei W, Li Y, Wang C, Gao S, Zhao Y, Yang Z, Wang H, Gao Z, Jiang Y, He Y, Zhao L, Gao H, Yao X, Hu Y
Pharmacological research 2022 Aug;182:106285
Pharmacological research 2022 Aug;182:106285
LncRNA H19 inhibits ER stress induced apoptosis and improves diabetic cardiomyopathy by regulating PI3K/AKT/mTOR axis.
Wang S, Duan J, Liao J, Wang Y, Xiao X, Li L, Liu Y, Gu H, Yang P, Fu D, Du J, Li X, Shao M
Aging 2022 Aug 30;14(16):6809-6828
Aging 2022 Aug 30;14(16):6809-6828
Non-Esterified Fatty Acid Induces ER Stress-Mediated Apoptosis via ROS/MAPK Signaling Pathway in Bovine Mammary Epithelial Cells.
Yan Y, Huang J, Huan C, Li L, Li C
Metabolites 2022 Aug 27;12(9)
Metabolites 2022 Aug 27;12(9)
Azoramide ameliorated tachypacing-induced injury of atrial myocytes differentiated from human induced pluripotent stem cell by regulating endoplasmic reticulum stress.
Miao W, Shi J, Huang J, Lin Y, Cui C, Zhu Y, Zheng B, Li M, Jiang Q, Chen M
Stem cell research 2022 Apr;60:102686
Stem cell research 2022 Apr;60:102686
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.
Li B, Huang J, Liu J, He F, Wen F, Yang C, Wang W, Wu T, Zhao T, Yao J, Liu S, Qiu Y, Fang M, Zeng J, Wu Z
Bioorganic chemistry 2022 Apr;121:105651
Bioorganic chemistry 2022 Apr;121:105651
Citrinin-Induced Hepatotoxicity in Mice Is Regulated by the Ca(2+)/Endoplasmic Reticulum Stress Signaling Pathway.
Wu D, Yang C, Yang M, Wu Y, Mao Y, Zhou X, Wang J, Yuan Z, Wu J
Toxins 2022 Apr 6;14(4)
Toxins 2022 Apr 6;14(4)
RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway.
Luo R, Liang H, Zhang W, Li G, Zhao K, Hua W, Song Y, Yang C
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):524-536
Acta biochimica et biophysica Sinica 2022 Apr 25;54(4):524-536
Exercise activates autophagy and regulates endoplasmic reticulum stress in muscle of high-fat diet mice to alleviate insulin resistance.
Cheng F, Dun Y, Cheng J, Ripley-Gonzalez JW, Jiang W, You B, Liu S
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Biochemical and biophysical research communications 2022 Apr 23;601:45-51
Chlorogenic acid improves the intestinal barrier by relieving endoplasmic reticulum stress and inhibiting ROCK/MLCK signaling pathways.
Song L, Wu T, Zhang L, Wan J, Ruan Z
Food & function 2022 Apr 20;13(8):4562-4575
Food & function 2022 Apr 20;13(8):4562-4575
Nicotinamide mononucleotide alleviates heat stress-induced oxidative stress and apoptosis in BMECs through reducing mitochondrial damage and endoplasmic reticulum stress.
Zeng HF, Xu J, Wang XL, Li SJ, Han ZY
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Ecotoxicology and environmental safety 2022 Apr 15;235:113441
Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling.
Liu Z, Yan M, Lei W, Jiang R, Dai W, Chen J, Wang C, Li L, Wu M, Nian X, Li D, Sun D, Lv X, Wang C, Xie C, Yao L, Wu C, Hu J, Xiao N, Mo W, Wang Z, Zhang L
The Journal of clinical investigation 2022 Apr 1;132(7)
The Journal of clinical investigation 2022 Apr 1;132(7)
Plasma Purification Treatment Relieves the Damage of Hyperlipidemia to PBMCs.
Zhang XM, Gu YH, Deng H, Xu ZQ, Zhong ZY, Lyu XJ, Jin HM, Yang XH
Frontiers in cardiovascular medicine 2021;8:691336
Frontiers in cardiovascular medicine 2021;8:691336
Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress-Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration.
Wang B, Ke W, Wang K, Li G, Ma L, Lu S, Xiang Q, Liao Z, Luo R, Song Y, Hua W, Wu X, Zhang Y, Zeng X, Yang C
Oxidative medicine and cellular longevity 2021;2021:8884922
Oxidative medicine and cellular longevity 2021;2021:8884922
Wenxin Granules Regulate Endoplasmic Reticulum Stress Unfolded Protein Response and Improve Ventricular Remodeling on Rats with Myocardial Infarction.
Liu K, Lv M, Ji X, Lou L, Nie B, Zhao J, Wu A, Zhao M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
Evidence-based complementary and alternative medicine : eCAM 2021;2021:7375549
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome.
Du Y, Zhong F, Cheng H, Li T, Chen Y, Tan P, Huang M, Liang T, Liu Y, Xia X, Fu W
Oxidative medicine and cellular longevity 2021;2021:4628050
Oxidative medicine and cellular longevity 2021;2021:4628050
Glucocorticoids protect HEI-OC1 cells from tunicamycin-induced cell damage via inhibiting endoplasmic reticulum stress.
Liu Z, Fei B, Xie L, Liu J, Chen X, Zhu W, Lv L, Ma W, Gao Z, Hou J, She W
Open life sciences 2021;16(1):695-702
Open life sciences 2021;16(1):695-702
Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.
Li T, Tang Z, Li C, Liu X, Cheng L, Yang Z, Zhu X, Liu W, Huang Y
Frontiers in pharmacology 2021;12:804615
Frontiers in pharmacology 2021;12:804615
Interventional Efects of the Topical of "Sanse Powder" Essential Oils Nanoemulsion on Knee Osteoarthritis in Rats by Targeting the ERS/TXNIP/NLRP3 Signaling Axis.
Liu Z, Liao T, Yang N, Ding L, Li X, Wu P, Wang P
Frontiers in pharmacology 2021;12:739644
Frontiers in pharmacology 2021;12:739644
IL-6/STAT3 Induced Neuron Apoptosis in Hypoxia by Downregulating ATF6 Expression.
Zhou S, Zhong Z, Huang P, Xiang B, Li X, Dong H, Zhang G, Wu Y, Li P
Frontiers in physiology 2021;12:729925
Frontiers in physiology 2021;12:729925
Extracts of Vine Tea Improve Diet-Induced Non-Alcoholic Steatohepatitis Through AMPK-LXRα Signaling.
Chen YJ, Song HY, Zhang ZW, Chen Q, Tang ZP, Gu M
Frontiers in pharmacology 2021;12:711763
Frontiers in pharmacology 2021;12:711763
Kaempferol Alleviates Steatosis and Inflammation During Early Non-Alcoholic Steatohepatitis Associated With Liver X Receptor α-Lysophosphatidylcholine Acyltransferase 3 Signaling Pathway.
Xiang H, Shao M, Lu Y, Wang J, Wu T, Ji G
Frontiers in pharmacology 2021;12:690736
Frontiers in pharmacology 2021;12:690736
Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis.
Xu J, Tang Z, He Y, Cai S, Wang B, Zhang S, Wu M, Qian K, Zhang K, Chai B, Chen G, Xu K, Ji H, Xiao J, Wu Y
Frontiers in pharmacology 2021;12:628950
Frontiers in pharmacology 2021;12:628950
Berberine Attenuates Cerebral Ischemia-Reperfusion Injury Induced Neuronal Apoptosis by Down-Regulating the CNPY2 Signaling Pathway.
Zhao L, Li H, Gao Q, Xu J, Zhu Y, Zhai M, Zhang P, Shen N, Di Y, Wang J, Chen T, Huang M, Sun J, Liu C
Frontiers in pharmacology 2021;12:609693
Frontiers in pharmacology 2021;12:609693
Lamprey Immune Protein Mediates Apoptosis of Lung Cancer Cells Via the Endoplasmic Reticulum Stress Signaling Pathway.
Song X, Xu X, Lu J, Chi X, Pang Y, Li Q
Frontiers in oncology 2021;11:663600
Frontiers in oncology 2021;11:663600
Selenium deficiency causes apoptosis through endoplasmic reticulum stress in swine small intestine.
Zheng Y, Zhang B, Guan H, Jiao X, Yang J, Cai J, Liu Q, Zhang Z
BioFactors (Oxford, England) 2021 Sep;47(5):788-800
BioFactors (Oxford, England) 2021 Sep;47(5):788-800
Ginsenoside Rb1 alleviates colitis in mice via activation of endoplasmic reticulum-resident E3 ubiquitin ligase Hrd1 signaling pathway.
Dong JY, Xia KJ, Liang W, Liu LL, Yang F, Fang XS, Xiong YJ, Wang L, Zhou ZJ, Li CY, Zhang WD, Wang JY, Chen DP
Acta pharmacologica Sinica 2021 Sep;42(9):1461-1471
Acta pharmacologica Sinica 2021 Sep;42(9):1461-1471
Upregulation of thioredoxin contributes to inhibiting diabetic hearing impairment.
Ren X, Lv J, Fu Y, Zhang N, Zhang C, Dong Z, Chudhary M, Zhong S, Kong L, Kong H
Diabetes research and clinical practice 2021 Sep;179:109025
Diabetes research and clinical practice 2021 Sep;179:109025
Role of UPR Sensor Activation in Cell Death-Survival Decision of Colon Cancer Cells Stressed by DPE Treatment.
Benedetti R, Gilardini Montani MS, Romeo MA, Arena A, Santarelli R, D'Orazi G, Cirone M
Biomedicines 2021 Sep 18;9(9)
Biomedicines 2021 Sep 18;9(9)
Autophagy protein NRBF2 attenuates endoplasmic reticulum stress-associated neuroinflammation and oxidative stress via promoting autophagosome maturation by interacting with Rab7 after SAH.
Zeng H, Chen H, Li M, Zhuang J, Peng Y, Zhou H, Xu C, Yu Q, Fu X, Cao S, Cai J, Yan F, Chen G
Journal of neuroinflammation 2021 Sep 16;18(1):210
Journal of neuroinflammation 2021 Sep 16;18(1):210
Hydrogen sulphide reduced the accumulation of lipid droplets in cardiac tissues of db/db mice via Hrd1 S-sulfhydration.
Sun Y, Zhang L, Lu B, Wen J, Wang M, Zhang S, Li Q, Shu F, Lu F, Liu N, Peng S, Zhao Y, Dong S, Lu F, Zhang W, Wang Y
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Journal of cellular and molecular medicine 2021 Oct;25(19):9154-9167
Expression liabilities in a four-chain bispecific molecule.
Guo C, Chen F, Xiao Q, Catterall HB, Robinson JH, Wang Z, Mock M, Hubert R
Biotechnology and bioengineering 2021 Oct;118(10):3744-3759
Biotechnology and bioengineering 2021 Oct;118(10):3744-3759
CK1δ stimulates ubiquitination-dependent proteasomal degradation of ATF4 to promote chemoresistance in gastric Cancer.
Feng L, Li M, Hu X, Li Y, Zhu L, Chen M, Wei Q, Xu W, Zhou Q, Wang W, Chen D, Wang X, Jin H
Clinical and translational medicine 2021 Oct;11(10):e587
Clinical and translational medicine 2021 Oct;11(10):e587
IL13Rα1 prevents a castration resistant phenotype of prostate cancer by targeting hexokinase 2 for ubiquitin-mediated degradation.
Feng T, Wang J, Cheng K, Lu Q, Zhao R, Wang S, Zhang Q, Ge L, Pan J, Song G, Wang L
Cancer biology & medicine 2021 Oct 18;19(7):1008-28
Cancer biology & medicine 2021 Oct 18;19(7):1008-28
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Tan X, Cai D, Chen N, Du S, Qiao D, Yue X, Wang T, Li J, Xie W, Wang H
Toxicology letters 2021 Oct 10;350:98-110
Toxicology letters 2021 Oct 10;350:98-110
2-Amino-3-Methylimidazo[4,5-f]quinoline Triggering Liver Damage by Inhibiting Autophagy and Inducing Endoplasmic Reticulum Stress in Zebrafish (Danio rerio).
Li D, Li Z, Zhang T, Peng B, Zhang Y, Sun H, Wang S
Toxins 2021 Nov 22;13(11)
Toxins 2021 Nov 22;13(11)
TLR4 deletion increases basal energy expenditure and attenuates heart apoptosis and ER stress but mitigates the training-induced cardiac function and performance improvement.
de Vicente LG, Muñoz VR, Pinto AP, Rovina RL, da Rocha AL, Marafon BB, Tavares MEA, Teixeira GR, Ferrari GD, Alberici LC, Frantz FG, Simabuco FM, Ropelle ER, de Moura LP, Cintra DE, Pauli JR, da Silva ASR
Life sciences 2021 Nov 15;285:119988
Life sciences 2021 Nov 15;285:119988
Suppression of alveolar bone resorption by salubrinal in a mouse model of periodontal disease.
Kimura F, Miyazawa K, Hamamura K, Tabuchi M, Sato T, Asano Y, Kako S, Aoki Y, Sugita Y, Maeda H, Togari A, Goto S
Life sciences 2021 Nov 1;284:119938
Life sciences 2021 Nov 1;284:119938
Autophagy triggers endoplasmic reticulum stress and C/EBP homologous protein-mediated apoptosis in OGD/R-treated neurons in a caspase-12-independent manner.
Tian Y, Wang L, Qiu Z, Xu Y, Hua R
Journal of neurophysiology 2021 Nov 1;126(5):1740-1750
Journal of neurophysiology 2021 Nov 1;126(5):1740-1750
The seed oil of Paeonia ludlowii ameliorates Aβ25-35-induced Alzheimer's disease in rats.
Lu YZ, Zhang CQ, Yu BX, Zhang EH, Quan H, Yin X, Cai H, Yuan F, Li LQ, Xu YJ, Su YJ, Xing YJ, Liao ZH, Lan XZ
Food science & nutrition 2021 May;9(5):2402-2413
Food science & nutrition 2021 May;9(5):2402-2413
Near-infrared emission Cu, N-doped carbon dots for human umbilical vein endothelial cell labeling and their biocompatibility in vitro.
Zhu P, Zhang T, Li J, Ma J, Ouyang X, Zhao X, Xu M, Wang D, Xu Q
Journal of applied toxicology : JAT 2021 May;41(5):789-798
Journal of applied toxicology : JAT 2021 May;41(5):789-798
Heme cytotoxicity is the consequence of endoplasmic reticulum stress in atherosclerotic plaque progression.
Pethő D, Hendrik Z, Nagy A, Beke L, Patsalos A, Nagy L, Póliska S, Méhes G, Tóth C, Potor L, Eaton JW, Jacob HS, Balla G, Balla J, Gáll T
Scientific reports 2021 May 17;11(1):10435
Scientific reports 2021 May 17;11(1):10435
Sirtuin 6 ameliorates alcohol-induced liver injury by reducing endoplasmic reticulum stress in mice.
Xin Y, Xu L, Zhang X, Yang C, Wang Q, Xiong X
Biochemical and biophysical research communications 2021 Mar 12;544:44-51
Biochemical and biophysical research communications 2021 Mar 12;544:44-51
Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway.
Liu X, Chen A, Liang Q, Yang X, Dong Q, Fu M, Wang S, Li Y, Ye Y, Lan Z, Chen Y, Ou JS, Yang P, Lu L, Yan J
Aging cell 2021 Jun;20(6):e13377
Aging cell 2021 Jun;20(6):e13377
4-Acetylantroquinonol B ameliorates nonalcoholic steatohepatitis by suppression of ER stress and NLRP3 inflammasome activation.
Yen IC, Tu QW, Chang TC, Lin PH, Li YF, Lee SY
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111504
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Jun;138:111504
Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells.
Zhu Q, Liu Z, Wang Y, Song E, Song Y
Journal of hazardous materials 2021 Jun 5;411:124958
Journal of hazardous materials 2021 Jun 5;411:124958
Combination of Palmitic Acid and Methylseleninic Acid Induces Mitochondria-Dependent Apoptosis via Attenuation of the IRE1α Arm and Enhancement of CHOP in Hepatoma.
Zhang H, Zheng Y, Han D, Lu J, Yin S, Hu H, Zhao C
ACS omega 2021 Jun 22;6(24):15708-15715
ACS omega 2021 Jun 22;6(24):15708-15715
Neutrophil extracellular traps impair intestinal barrier functions in sepsis by regulating TLR9-mediated endoplasmic reticulum stress pathway.
Sun S, Duan Z, Wang X, Chu C, Yang C, Chen F, Wang D, Wang C, Li Q, Ding W
Cell death & disease 2021 Jun 11;12(6):606
Cell death & disease 2021 Jun 11;12(6):606
Polybrominated diphenyl ethers quinone-induced intracellular protein oxidative damage triggers ubiquitin-proteasome and autophagy-lysosomal system activation in LO2 cells.
Wang Y, Xu L, Peng L, Fang C, Qin Q, Lv X, Liu Z, Yang B, Song E, Song Y
Chemosphere 2021 Jul;275:130034
Chemosphere 2021 Jul;275:130034
Comparison of multi-walled carbon nanotubes and halloysite nanotubes on lipid profiles in human umbilical vein endothelial cells.
Liu Y, Hu Q, Huang C, Cao Y
NanoImpact 2021 Jul;23:100333
NanoImpact 2021 Jul;23:100333
Untargeted metabolomics and transcriptomics identified glutathione metabolism disturbance and PCS and TMAO as potential biomarkers for ER stress in lung.
Wang Z, Ma P, Wang Y, Hou B, Zhou C, Tian H, Li B, Shui G, Yang X, Qiang G, Yin C, Du G
Scientific reports 2021 Jul 19;11(1):14680
Scientific reports 2021 Jul 19;11(1):14680
Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis.
Al-Yacoub N, Colak D, Mahmoud SA, Hammonds M, Muhammed K, Al-Harazi O, Assiri AM, Al-Buraiki J, Al-Habeeb W, Poizat C
Communications biology 2021 Jul 16;4(1):884
Communications biology 2021 Jul 16;4(1):884
Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells.
Sang J, Li W, Diao HJ, Fan RZ, Huang JL, Gan L, Zou MF, Tang GH, Yin S
Cancer letters 2021 Jul 1;509:13-25
Cancer letters 2021 Jul 1;509:13-25
Chromosome 22q11.2 deletion causes PERK-dependent vulnerability in dopaminergic neurons.
Arioka Y, Shishido E, Kushima I, Suzuki T, Saito R, Aiba A, Mori D, Ozaki N
EBioMedicine 2021 Jan;63:103138
EBioMedicine 2021 Jan;63:103138
Thrombospondin 1-induced exosomal proteins attenuate hypoxia-induced paraptosis in corneal epithelial cells and promote wound healing.
Lai YH, Lee PY, Lu CY, Liu YR, Wang SC, Liu CC, Chang YC, Chen YH, Su CC, Li CY, Liu PL
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21200
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Jan;35(1):e21200
Effects of ER-resident and secreted AGR2 on cell proliferation, migration, invasion, and survival in PANC-1 pancreatic cancer cells.
Hong X, Li ZX, Hou J, Zhang HY, Zhang CY, Zhang J, Sun H, Pang LH, Wang T, Deng ZH
BMC cancer 2021 Jan 7;21(1):33
BMC cancer 2021 Jan 7;21(1):33
Autophagy impairment as a key feature for acetaminophen-induced ototoxicity.
Zhao T, Zheng T, Yu H, Hu BH, Hu B, Ma P, Yang Y, Yang N, Hu J, Cao T, Chen G, Yan B, Peshoff M, Hatzoglou M, Geng R, Li B, Zheng QY
Cell death & disease 2021 Jan 4;12(1):3
Cell death & disease 2021 Jan 4;12(1):3
MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice.
Liu L, Yan LN, Sui Z
Life sciences 2021 Jan 15;265:118744
Life sciences 2021 Jan 15;265:118744
Microcystin-leucine arginine induced the apoptosis of GnRH neurons by activating the endoplasmic reticulum stress resulting in a decrease of serum testosterone level in mice.
Jin H, Hou J, Meng X, Ma T, Wang B, Liu Z, Sha X, Ding J, Han X
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Ecotoxicology and environmental safety 2021 Jan 15;208:111748
Cytosolic PINK1 orchestrates protein translation during proteasomal stress by phosphorylating the translation elongation factor eEF1A1.
Qin S, Ye L, Zheng Y, Gao J
FEBS letters 2021 Feb;595(4):507-520
FEBS letters 2021 Feb;595(4):507-520
Boron Attenuates Heat Stress-Induced Apoptosis by Inhibiting Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Jin E, Yin Q, Che C, He S
Biological trace element research 2021 Feb;199(2):611-621
Biological trace element research 2021 Feb;199(2):611-621
Impact of knockdown LincRNA-Cox2 on apoptosis of macrophage infected with Bacillus Calmette-Guérin.
Xu Y, Yu J, Ma C, Gong Z, Wu X, Deng G
Molecular immunology 2021 Feb;130:85-95
Molecular immunology 2021 Feb;130:85-95
AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo.
Ribas VT, Vahsen BF, Tatenhorst L, Estrada V, Dambeck V, Almeida RA, Bähr M, Michel U, Koch JC, Müller HW, Lingor P
Cell death & disease 2021 Feb 26;12(2):213
Cell death & disease 2021 Feb 26;12(2):213
Cigarette smoke extracts induce apoptosis in Raw264.7 cells via endoplasmic reticulum stress and the intracellular Ca(2+)/P38/STAT1 pathway.
Feng H, Li M, Altawil A, Yin Y, Zheng R, Kang J
Toxicology in vitro : an international journal published in association with BIBRA 2021 Dec;77:105249
Toxicology in vitro : an international journal published in association with BIBRA 2021 Dec;77:105249
Endoplasmic reticulum stress pathway mediates T-2 toxin-induced chondrocyte apoptosis.
Liu YN, Mu YD, Wang H, Zhang M, Shi YW, Mi G, Peng LX, Chen JH
Toxicology 2021 Dec;464:152989
Toxicology 2021 Dec;464:152989
Reticulocalbin 1 is required for proliferation and migration of non-small cell lung cancer cells regulated by osteoblast-conditioned medium.
Fu H, Chen R, Wang Y, Xu Y, Xia C, Zhang B
Journal of cellular and molecular medicine 2021 Dec;25(24):11198-11211
Journal of cellular and molecular medicine 2021 Dec;25(24):11198-11211
Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice.
Xianchu L, Ming L, Changhao C, Beiwang D, Jingtao X
Iranian journal of basic medical sciences 2021 Dec;24(12):1695-1701
Iranian journal of basic medical sciences 2021 Dec;24(12):1695-1701
Deficiency of β-arrestin2 alleviates apoptosis through GRP78-ATF6-CHOP signaling pathway in primary Sjögren's syndrome.
Huang L, Liu Q, Zhou T, Zhang J, Tian Q, Zhang Q, Wei W, Wu H
International immunopharmacology 2021 Dec;101(Pt A):108281
International immunopharmacology 2021 Dec;101(Pt A):108281
Mannan-binding lectin deficiency augments hepatic endoplasmic reticulum stress through IP3R-controlled calcium release.
Chen Y, Hu M, Deng F, Wang P, Lin J, Zheng Z, Liu Y, Dong L, Lu X, Chen Z, Zhou J, Zuo D
Cell calcium 2021 Dec;100:102477
Cell calcium 2021 Dec;100:102477
Long non-coding RNA RP5-821D11.7 promotes proliferation, migration, and epithelial-mesenchymal transition in glioma and glioma stem-like cells.
Younis M, Shaikh S, Shahzad KA
Progress in biophysics and molecular biology 2021 Dec 21;
Progress in biophysics and molecular biology 2021 Dec 21;
Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity.
Miyake M, Zhang J, Yasue A, Hisanaga S, Tsugawa K, Sakaue H, Oyadomari M, Kiyonari H, Oyadomari S
iScience 2021 Dec 17;24(12):103448
iScience 2021 Dec 17;24(12):103448
Diosgenin Protects Against Kidney Injury and Mitochondrial Apoptosis Induced by 3-MCPD Through the Regulation of ER Stress, Ca(2+) Homeostasis, and Bcl2 Expression.
Zhong Y, Jin C, Han J, Zhu J, Liu Q, Sun D, Xia X, Zhang Y, Peng X
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Molecular nutrition & food research 2021 Aug;65(15):e2001202
Sulforaphane protects against oxidative stress‑induced apoptosis via activating SIRT1 in mouse osteoarthritis.
Chen M, Huang L, Lv Y, Li L, Dong Q
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Integration of Metabolomics and Transcriptomics Reveals Ketone Body and Lipid Metabolism Disturbance Related to ER Stress in the Liver.
Ma P, Wang Z, Wang Y, Hou B, Sun J, Tian H, Li B, Shui G, Yang X, Yang X, Qiang G, Liew CW, Du G
Journal of proteome research 2021 Aug 6;20(8):3875-3888
Journal of proteome research 2021 Aug 6;20(8):3875-3888
KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats.
Iwai S, Ikeda HO, Mera H, Nishitani K, Saito M, Tsujikawa A, Kakizuka A
Scientific reports 2021 Aug 2;11(1):15651
Scientific reports 2021 Aug 2;11(1):15651
Estrogen Regulates Endoplasmic Reticulum Stress-Mediated Apoptosis by ERK-p65 Pathway to Promote Endometrial Angiogenesis.
Zhang Y, Cao C, Du S, Fan L, Zhang D, Wang X, He M
Reproductive sciences (Thousand Oaks, Calif.) 2021 Apr;28(4):1216-1226
Reproductive sciences (Thousand Oaks, Calif.) 2021 Apr;28(4):1216-1226
ARFGAP1 binds to classical swine fever virus NS5A protein and enhances CSFV replication in PK-15 cells.
Zhang L, Jin M, Song M, Liu S, Wang T, Guo K, Zhang Y
Veterinary microbiology 2021 Apr;255:109034
Veterinary microbiology 2021 Apr;255:109034
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo.
Yen IC, Lin JC, Chen Y, Tu QW, Lee SY
The American journal of Chinese medicine 2020;48(8):1859-1874
The American journal of Chinese medicine 2020;48(8):1859-1874
Methane-Rich Saline Alleviates CA/CPR Brain Injury by Inhibiting Oxidative Stress, Microglial Activation-Induced Inflammatory Responses, and ER Stress-Mediated Apoptosis.
Cui R, Liu S, Wang C, Liu T, Ren J, Jia Y, Tong Y, Liu C, Zhang J
Oxidative medicine and cellular longevity 2020;2020:8829328
Oxidative medicine and cellular longevity 2020;2020:8829328
Topical Application of Fibroblast Growth Factor 10-PLGA Microsphere Accelerates Wound Healing via Inhibition of ER Stress.
Xu K, Chai B, Zhang K, Xiong J, Zhu Y, Xu J, An N, Xia W, Ji H, Wu Y, Li H, Xiao J, Feng Z, Zhang H
Oxidative medicine and cellular longevity 2020;2020:8586314
Oxidative medicine and cellular longevity 2020;2020:8586314
Nanosecond pulsed electric fields induce the integrated stress response via reactive oxygen species-mediated heme-regulated inhibitor (HRI) activation.
Hamada Y, Furumoto Y, Izutani A, Taniuchi S, Miyake M, Oyadomari M, Teranishi K, Shimomura N, Oyadomari S
PloS one 2020;15(3):e0229948
PloS one 2020;15(3):e0229948
Sepsis causes heart injury through endoplasmic reticulum stress-mediated apoptosis signaling pathway.
Li L, Peng X, Guo L, Zhao Y, Cheng Q
International journal of clinical and experimental pathology 2020;13(5):964-971
International journal of clinical and experimental pathology 2020;13(5):964-971
Chlorin A-mediated photodynamic therapy induced apoptosis in human cholangiocarcinoma cells via impaired autophagy flux.
He C, Xia J, Gao Y, Chen Z, Wan X
American journal of translational research 2020;12(9):5080-5094
American journal of translational research 2020;12(9):5080-5094
Role of Endoplasmic Reticulum Stress in Otitis Media.
Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu BH, Che J, Zhao T, Chen J, Hatzoglou M, Zhang X, Fan Z, Zheng Q
Frontiers in genetics 2020;11:495
Frontiers in genetics 2020;11:495
Maimendong Decoction Improves Pulmonary Function in Rats With Idiopathic Pulmonary Fibrosis by Inhibiting Endoplasmic Reticulum Stress in AECIIs.
Shen M, Nan Y, Zhang L, Di L, He S, Li Y, Li Y
Frontiers in pharmacology 2020;11:1262
Frontiers in pharmacology 2020;11:1262
EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.
Chen T, Xu J, Fu W
Frontiers in oncology 2020;10:1688
Frontiers in oncology 2020;10:1688
The SIRT6-Autophagy-Warburg Effect Axis in Papillary Thyroid Cancer.
Yang Z, Huang R, Wei X, Yu W, Min Z, Ye M
Frontiers in oncology 2020;10:1265
Frontiers in oncology 2020;10:1265
Apigetrin ameliorates streptozotocin-induced pancreatic β-cell damages via attenuating endoplasmic reticulum stress.
Zhang R, Shi J, Wang T, Qiu X, Liu R, Li Y, Gao Q, Wang N
In vitro cellular & developmental biology. Animal 2020 Sep;56(8):622-634
In vitro cellular & developmental biology. Animal 2020 Sep;56(8):622-634
A paralog-specific role of COPI vesicles in the neuronal differentiation of mouse pluripotent cells.
Jain Goyal M, Zhao X, Bozhinova M, Andrade-López K, de Heus C, Schulze-Dramac S, Müller-McNicoll M, Klumperman J, Béthune J
Life science alliance 2020 Sep;3(9)
Life science alliance 2020 Sep;3(9)
Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway.
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, Zhang J, Jing W, Cong B, Ma C
Brain research bulletin 2020 Sep;162:73-83
Brain research bulletin 2020 Sep;162:73-83
Asiatic acid ameliorates acute hepatic injury by reducing endoplasmic reticulum stress and triggering hepatocyte autophagy.
Pang X, Qiao Q, Vonglorkham S, Feng Z, Pang L, Chen S, Wang D, Lao L, Lin X, Wei J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110375
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Sep;129:110375
Reactive oxygen species mediate anlotinib-induced apoptosis via activation of endoplasmic reticulum stress in pancreatic cancer.
Yang L, Zhou X, Sun J, Lei Q, Wang Q, Pan D, Ding M, Ding Y
Cell death & disease 2020 Sep 17;11(9):766
Cell death & disease 2020 Sep 17;11(9):766
Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress.
Yao X, Li K, Liang C, Zhou Z, Wang J, Wang S, Liu L, Yu CL, Song ZB, Bao YL, Zheng LH, Sun Y, Wang G, Huang Y, Yi J, Sun L, Li Y
The Journal of biological chemistry 2020 Sep 11;295(37):12975-12992
The Journal of biological chemistry 2020 Sep 11;295(37):12975-12992
Lycopene protects neuroblastoma cells against oxidative damage via depression of ER stress.
Ou S, Fang Y, Tang H, Wu T, Chen L, Jiang M, Zhou L, Xu J, Guo K
Journal of food science 2020 Oct;85(10):3552-3561
Journal of food science 2020 Oct;85(10):3552-3561
FABP4 inhibitor BMS309403 protects against hypoxia-induced H9c2 cardiomyocyte apoptosis through attenuating endoplasmic reticulum stress.
Sun F, Du J, Li H, Hao S, Zhao G, Lu F
Journal of cellular and molecular medicine 2020 Oct;24(19):11188-11197
Journal of cellular and molecular medicine 2020 Oct;24(19):11188-11197
Melatonin inhibits oxalate-induced endoplasmic reticulum stress and apoptosis in HK-2 cells by activating the AMPK pathway.
Song Q, He Z, Li B, Liu J, Liu L, Liao W, Xiong Y, Song C, Yang S, Liu Y
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Cell cycle (Georgetown, Tex.) 2020 Oct;19(20):2600-2610
Neuroprotective mechanism of L-cysteine after subarachnoid hemorrhage.
Xiong Y, Xin DQ, Hu Q, Wang LX, Qiu J, Yuan HT, Chu XL, Liu DX, Li G, Wang Z
Neural regeneration research 2020 Oct;15(10):1920-1930
Neural regeneration research 2020 Oct;15(10):1920-1930
T-type calcium channel blockade induces apoptosis in C2C12 myotubes and skeletal muscle via endoplasmic reticulum stress activation.
Chen M, Li S, Hao M, Chen J, Zhao Z, Hong S, Min J, Tang J, Hu M, Hong L
FEBS open bio 2020 Oct;10(10):2122-2136
FEBS open bio 2020 Oct;10(10):2122-2136
Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE(-/-) mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage.
Ma R, Qi Y, Zhao X, Li X, Sun X, Niu P, Li Y, Guo C, Chen R, Sun Z
Particle and fibre toxicology 2020 Oct 2;17(1):50
Particle and fibre toxicology 2020 Oct 2;17(1):50
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Li B, Yao J, Guo K, He F, Chen K, Lin Z, Liu S, Huang J, Wu Q, Fang M, Zeng J, Wu Z
European journal of medicinal chemistry 2020 Oct 15;204:112608
European journal of medicinal chemistry 2020 Oct 15;204:112608
Aging is associated with increased TRB3, ER stress, and hepatic glucose production in the liver of rats.
Gaspar RC, Muñoz VR, Nakandakari SCBR, Vieira RFL, da Conceição LR, de Oliveira F, Crisol BM, da Silva ASR, Cintra DE, de Moura LP, Ropelle ER, Zaghloul I, Mekary RA, Pauli JR
Experimental gerontology 2020 Oct 1;139:111021
Experimental gerontology 2020 Oct 1;139:111021
Knockdown of fatty acid binding protein 4 exacerbates Bacillus Calmette-Guerin infection-induced RAW264.7 cell apoptosis via the endoplasmic reticulum stress pathway.
Yu J, Ma C, Xu Y, Han L, Wu X, Wang Y, Deng G
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Nov;85:104552
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2020 Nov;85:104552
TRPV4 contributes to ER stress: Relation to apoptosis in the MPP(+)-induced cell model of Parkinson's disease.
Liu N, Liu J, Wen X, Bai L, Shao R, Bai J
Life sciences 2020 Nov 15;261:118461
Life sciences 2020 Nov 15;261:118461
Targeted inhibition of GRP78 by HA15 promotes apoptosis of lung cancer cells accompanied by ER stress and autophagy.
Wu J, Wu Y, Lian X
Biology open 2020 Nov 12;9(11)
Biology open 2020 Nov 12;9(11)
Acupuncture protects against cerebral ischemia-reperfusion injury via suppressing endoplasmic reticulum stress-mediated autophagy and apoptosis.
Sun X, Liu H, Sun Z, Zhang B, Wang X, Liu T, Pan T, Gao Y, Jiang X, Li H
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Molecular medicine (Cambridge, Mass.) 2020 Nov 10;26(1):105
Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor.
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, Shao X, Song N, Zhao Y, Li H, Yang G, Xu C, Wei C
Redox biology 2020 May;32:101514
Redox biology 2020 May;32:101514
Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells.
Zhang XM, Wang YZ, Tong JD, Ning XC, Zhou FQ, Yang XH, Jin HM
FEBS open bio 2020 May;10(5):827-834
FEBS open bio 2020 May;10(5):827-834
Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling.
Yao Y
Molecular medicine reports 2020 Mar;21(3):1059-1070
Molecular medicine reports 2020 Mar;21(3):1059-1070
Proscillaridin A slows the prostate cancer progression through triggering the activation of endoplasmic reticulum stress.
Wang F, Liu L, Tong Y, Li L, Liu Y, Gao WQ
Cell cycle (Georgetown, Tex.) 2020 Mar;19(5):541-550
Cell cycle (Georgetown, Tex.) 2020 Mar;19(5):541-550
A novel splice site indel alteration in the EIF2AK3 gene is responsible for the first cases of Wolcott-Rallison syndrome in Hungary.
Sümegi A, Hendrik Z, Gáll T, Felszeghy E, Szakszon K, Antal-Szalmás P, Beke L, Papp Á, Méhes G, Balla J, Balla G
BMC medical genetics 2020 Mar 27;21(1):61
BMC medical genetics 2020 Mar 27;21(1):61
Astrocyte elevated gene 1 (AEG-1) promotes anoikis resistance and metastasis by inducing autophagy in hepatocellular carcinoma.
Zhu HD, Liu L, Deng H, Li ZB, Sheng JQ, He XX, Tian DA, Li PY
Journal of cellular physiology 2020 Jun;235(6):5084-5095
Journal of cellular physiology 2020 Jun;235(6):5084-5095
Sulforaphane attenuates apoptosis of hippocampal neurons induced by high glucose via regulating endoplasmic reticulum.
Tang L, Ren X, Han Y, Chen L, Meng X, Zhang C, Chu H, Kong L, Ma H
Neurochemistry international 2020 Jun;136:104728
Neurochemistry international 2020 Jun;136:104728
Activation of GCN2/ATF4 signals in amygdalar PKC-δ neurons promotes WAT browning under leucine deprivation.
Yuan F, Jiang H, Yin H, Jiang X, Jiao F, Chen S, Ying H, Chen Y, Zhai Q, Guo F
Nature communications 2020 Jun 5;11(1):2847
Nature communications 2020 Jun 5;11(1):2847
Excretory/secretory products of Angiostrongylus cantonensis fifth-stage larvae induce endoplasmic reticulum stress via the Sonic hedgehog pathway in mouse astrocytes.
Chen KY, Chen YJ, Cheng CJ, Jhan KY, Wang LC
Parasites & vectors 2020 Jun 18;13(1):317
Parasites & vectors 2020 Jun 18;13(1):317
Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway.
Wang Y, Li C, Li J, Wang G, Li L
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Antioxidants (Basel, Switzerland) 2020 Jun 14;9(6)
Circulating Exosomes From Lipopolysaccharide-Induced Ards Mice Trigger Endoplasmic Reticulum Stress in Lung Tissue.
Tang X, Yu Q, Wen X, Qi D, Peng J, He J, Deng W, Zhu T, Zhao Y, Wang D
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
Shock (Augusta, Ga.) 2020 Jul;54(1):110-118
4-Phenylbutyrate Prevents Endoplasmic Reticulum Stress-Mediated Apoptosis Induced by Heatstroke in the Intestines of Mice.
Cao Y, Liu Z, Xiao W, Gu Z, Xiao G, Yuan F, Chen F, Pei Y, Li H, Su L
Shock (Augusta, Ga.) 2020 Jul;54(1):102-109
Shock (Augusta, Ga.) 2020 Jul;54(1):102-109
ALA protects against ERS-mediated apoptosis in a cochlear cell model with low citrate synthase expression.
Xu A, Shang W, Wang Y, Sun X, Zhou B, Xie Y, Xu X, Liu T, Han F
Archives of biochemistry and biophysics 2020 Jul 30;688:108402
Archives of biochemistry and biophysics 2020 Jul 30;688:108402
TMEM216 Deletion Causes Mislocalization of Cone Opsin and Rhodopsin and Photoreceptor Degeneration in Zebrafish.
Liu Y, Cao S, Yu M, Hu H
Investigative ophthalmology & visual science 2020 Jul 1;61(8):24
Investigative ophthalmology & visual science 2020 Jul 1;61(8):24
Liraglutide protects pancreatic β cells from endoplasmic reticulum stress by upregulating MANF to promote autophagy turnover.
Fu J, Nchambi KM, Wu H, Luo X, An X, Liu D
Life sciences 2020 Jul 1;252:117648
Life sciences 2020 Jul 1;252:117648
Withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4-ATF3-CHOP axis.
Tang Q, Ren L, Liu J, Li W, Zheng X, Wang J, Du G
Cell proliferation 2020 Jan;53(1):e12706
Cell proliferation 2020 Jan;53(1):e12706
Minocycline induces apoptosis of photoreceptor cells by regulating ER stress.
Xu W, Tao M, Hu Z, Chang T, Wang Y
Experimental eye research 2020 Jan;190:107887
Experimental eye research 2020 Jan;190:107887
Baicalein Alleviates Liver Oxidative Stress and Apoptosis Induced by High-Level Glucose through the Activation of the PERK/Nrf2 Signaling Pathway.
Dong Y, Xing Y, Sun J, Sun W, Xu Y, Quan C
Molecules (Basel, Switzerland) 2020 Jan 30;25(3)
Molecules (Basel, Switzerland) 2020 Jan 30;25(3)
Selenium Attenuates Chronic Heat Stress-Induced Apoptosis via the Inhibition of Endoplasmic Reticulum Stress in Mouse Granulosa Cells.
Xiong Y, Yin Q, Jin E, Chen H, He S
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
Molecules (Basel, Switzerland) 2020 Jan 28;25(3)
MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR.
Zhang W, Zhu T, Chen L, Luo W, Chao J
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
American journal of physiology. Heart and circulatory physiology 2020 Jan 1;318(1):H59-H71
N-glycosylation of uterine endometrium determines its receptivity.
Yu M, Qin H, Wang H, Liu J, Liu S, Yan Q
Journal of cellular physiology 2020 Feb;235(2):1076-1089
Journal of cellular physiology 2020 Feb;235(2):1076-1089
Hydrogen sulfide regulates muscle RING finger-1 protein S-sulfhydration at Cys(44) to prevent cardiac structural damage in diabetic cardiomyopathy.
Sun X, Zhao D, Lu F, Peng S, Yu M, Liu N, Sun Y, Du H, Wang B, Chen J, Dong S, Lu F, Zhang W
British journal of pharmacology 2020 Feb;177(4):836-856
British journal of pharmacology 2020 Feb;177(4):836-856
Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes.
Xiong Y, Yin Q, Li J, He S
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
Animals : an open access journal from MDPI 2020 Feb 27;10(3)
Melatonin protects against Epirubicin-induced ovarian damage.
Wang N, Li H, Zhu Y, Li N, Chen ZJ, Zhang C
The Journal of reproduction and development 2020 Feb 14;66(1):19-27
The Journal of reproduction and development 2020 Feb 14;66(1):19-27
Fengbaisan suppresses endoplasmic reticulum stress by up-regulating SIRT1 expression to protect rats with chronic obstructive pulmonary diseases.
Wang Y, Su NX, Pan SG, Ge XP, Dai XP
Pharmaceutical biology 2020 Dec;58(1):878-885
Pharmaceutical biology 2020 Dec;58(1):878-885
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Gou W, Luo N, Wei H, Wu H, Yu X, Duan Y, Bi C, Ning H, Hou W, Li Y
Pharmaceutical biology 2020 Dec;58(1):707-715
Pharmaceutical biology 2020 Dec;58(1):707-715
Mitochondrial serine protease Omi/HtrA2 accentuates brain ischemia/reperfusion injury in rats and oxidative stress injury in vitro by modulating mitochondrial stress proteins CHOP and ClpP and physically interacting with mitochondrial fusion protein OPA1.
You H, Jin Y, Kang J, Mao Y, Su J, Sun L, Wang L, Meng H
Bioengineered 2020 Dec;11(1):1058-1070
Bioengineered 2020 Dec;11(1):1058-1070
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress-autophagy axis and improves myocardial reconstruction after acute myocardial infarction.
Li Y, Liu M, Yi J, Song X, Zheng X, Liu D, Wang S, Chu C, Yang J
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Acta biochimica et biophysica Sinica 2020 Dec 29;52(12):1325-1336
Mitochondrial Nuclear Retrograde Regulator 1 (MNRR1) rescues the cellular phenotype of MELAS by inducing homeostatic mechanisms.
Aras S, Purandare N, Gladyck S, Somayajulu-Nitu M, Zhang K, Wallace DC, Grossman LI
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Proceedings of the National Academy of Sciences of the United States of America 2020 Dec 15;117(50):32056-32065
Phosphorylation of eIF2α signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner.
Li J, Li X, Liu D, Zhang S, Tan N, Yokota H, Zhang P
Cell death & disease 2020 Dec 14;11(12):1069
Cell death & disease 2020 Dec 14;11(12):1069
Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.
Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, Wang J, Sun L
IUBMB life 2020 Aug;72(8):1659-1679
IUBMB life 2020 Aug;72(8):1659-1679
The protective effects of phoenixin-14 against lipopolysaccharide-induced inflammation and inflammasome activation in astrocytes.
Wang J, Zheng B, Yang S, Tang X, Wang J, Wei D
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Aug;69(8):779-787
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2020 Aug;69(8):779-787
Cell cycle exit during bortezomib-induced osteogenic differentiation of mesenchymal stem cells was mediated by Xbp1s-upregulated p21(Cip1) and p27(Kip1).
Zhang D, Fan R, Lei L, Lei L, Wang Y, Lv N, Chen P, Williamson RA, Wang B, Hu J
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Journal of cellular and molecular medicine 2020 Aug;24(16):9428-9438
Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol.
Wang TE, Lai YH, Yang KC, Lin SJ, Chen CL, Tsai PS
Antioxidants (Basel, Switzerland) 2020 Aug 9;9(8)
Antioxidants (Basel, Switzerland) 2020 Aug 9;9(8)
IL13Rα1 protects against rheumatoid arthritis by combating the apoptotic resistance of fibroblast-like synoviocytes.
Yang X, Guo Q, Feng T, Lu Q, Ge L, Pan J, Bi K, Qiao L, Tian L, Xie T, Yao C, Song G, Wang L
Arthritis research & therapy 2020 Aug 8;22(1):184
Arthritis research & therapy 2020 Aug 8;22(1):184
25-Hydroxycholesterol promotes vascular calcification via activation of endoplasmic reticulum stress.
Dong Q, Chen Y, Liu W, Liu X, Chen A, Yang X, Li Y, Wang S, Fu M, Ou JS, Lu L, Yan J
European journal of pharmacology 2020 Aug 5;880:173165
European journal of pharmacology 2020 Aug 5;880:173165
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Song L, Piao Z, Yao L, Zhang L, Lu Y
Experimental animals 2020 Aug 5;69(3):363-373
Experimental animals 2020 Aug 5;69(3):363-373
N6-(2-hydroxyethyl)-Adenosine Induces Apoptosis via ER Stress and Autophagy of Gastric Carcinoma Cells In Vitro and In Vivo.
Xie H, Li X, Yang W, Yu L, Jiang X, Chen Y, Shen Z, Li C, Gu M, Shi L
International journal of molecular sciences 2020 Aug 13;21(16)
International journal of molecular sciences 2020 Aug 13;21(16)
Artemisinin and dihydroartemisinin promote β-cell apoptosis induced by palmitate via enhancing ER stress.
Chen K, Hua H, Zhu Z, Wu T, Jia Z, Liu Q
Apoptosis : an international journal on programmed cell death 2020 Apr;25(3-4):192-204
Apoptosis : an international journal on programmed cell death 2020 Apr;25(3-4):192-204
All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells.
Zhang L, Zhou Y, Xia Q, Chen Y, Li J
Toxicology letters 2020 Apr 1;322:77-86
Toxicology letters 2020 Apr 1;322:77-86
Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo.
Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, Hua W, Zhang Y, Wu X, Yang C
Theranostics 2019;9(14):4084-4100
Theranostics 2019;9(14):4084-4100
Betulinic Acid Suppresses Breast Cancer Metastasis by Targeting GRP78-Mediated Glycolysis and ER Stress Apoptotic Pathway.
Zheng Y, Liu P, Wang N, Wang S, Yang B, Li M, Chen J, Situ H, Xie M, Lin Y, Wang Z
Oxidative medicine and cellular longevity 2019;2019:8781690
Oxidative medicine and cellular longevity 2019;2019:8781690
Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress.
Zheng D, Chen Y, Ai S, Zhang R, Gao Z, Liang C, Cao L, Chen Y, Hong Z, Shi Y, Wang L, Li X, Yang Z
Research (Washington, D.C.) 2019;2019:4803624
Research (Washington, D.C.) 2019;2019:4803624
Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells.
Huang W, Liang Y, Ma X
Cancer cell international 2019;19:151
Cancer cell international 2019;19:151
Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?
Sun Y, Gong J, Cao Y
International journal of nanomedicine 2019;14:9285-9294
International journal of nanomedicine 2019;14:9285-9294
Autophagy Activation Is Involved in Acidic Fibroblast Growth Factor Ameliorating Parkinson's Disease via Regulating Tribbles Homologue 3.
Zhong X, Wang B, Zhang G, Yuan Y, Hu X, Xiong J, Zheng P, Liu Y, Xu K, Xiao J, Wu Y, Ye J
Frontiers in pharmacology 2019;10:1428
Frontiers in pharmacology 2019;10:1428
Vildagliptin Reduces Stenosis of Injured Carotid Artery in Diabetic Mouse Through Inhibiting Vascular Smooth Muscle Cell Proliferation via ER Stress/NF-κB Pathway.
Ji Y, Ge Y, Xu X, Ye S, Fan Y, Zhang J, Mei L, Zhang X, Ying L, Yang T, Li C
Frontiers in pharmacology 2019;10:142
Frontiers in pharmacology 2019;10:142
Effect of endoplasmic reticulum calcium on paraquat‑induced apoptosis of human lung type II alveolar epithelial A549 cells.
Song CQ, Sun DZ, Xu YM, Yang C, Cai Q, Dong XS
Molecular medicine reports 2019 Sep;20(3):2419-2425
Molecular medicine reports 2019 Sep;20(3):2419-2425
Multi-walled carbon nanotubes (MWCNTs) promoted lipid accumulation in THP-1 macrophages through modulation of endoplasmic reticulum (ER) stress.
Long J, Ma W, Yu Z, Liu H, Cao Y
Nanotoxicology 2019 Sep;13(7):938-951
Nanotoxicology 2019 Sep;13(7):938-951
Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line.
Xin XL, Zhang R, Yuan XM, Liu L
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 22;25:7100-7114
Medical science monitor : international medical journal of experimental and clinical research 2019 Sep 22;25:7100-7114
Lysosomal dysfunction is associated with persistent lung injury in dams caused by pregnancy exposure to carbon black nanoparticles.
Liu X, Tu B, Jiang X, Xu G, Bai L, Zhang L, Meng P, Qin X, Chen C, Zou Z
Life sciences 2019 Sep 15;233:116741
Life sciences 2019 Sep 15;233:116741
Japanese Encephalitis Virus Induces Apoptosis and Encephalitis by Activating the PERK Pathway.
Wang Q, Xin X, Wang T, Wan J, Ou Y, Yang Z, Yu Q, Zhu L, Guo Y, Wu Y, Ding Z, Zhang Y, Pan Z, Tang Y, Li S, Kong L
Journal of virology 2019 Sep 1;93(17)
Journal of virology 2019 Sep 1;93(17)
Endoplasmic reticulum stress and autophagy contribute to cadmium-induced cytotoxicity in retinal pigment epithelial cells.
Zhang L, Xia Q, Zhou Y, Li J
Toxicology letters 2019 Sep 1;311:105-113
Toxicology letters 2019 Sep 1;311:105-113
Autophagy protects HUVECs against ER stress-mediated apoptosis under simulated microgravity.
Li CF, Pan YK, Gao Y, Shi F, Wang YC, Sun XQ
Apoptosis : an international journal on programmed cell death 2019 Oct;24(9-10):812-825
Apoptosis : an international journal on programmed cell death 2019 Oct;24(9-10):812-825
Resveratrol reduces brain injury after subarachnoid hemorrhage by inhibiting oxidative stress and endoplasmic reticulum stress.
Xie YK, Zhou X, Yuan HT, Qiu J, Xin DQ, Chu XL, Wang DC, Wang Z
Neural regeneration research 2019 Oct;14(10):1734-1742
Neural regeneration research 2019 Oct;14(10):1734-1742
Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1.
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, Lu H, Wang L, Huang D, Sun L, Li T, He X, Zhong X, Wang J, Gao P, Smith ZJ, Jia W, Zhang H
EMBO reports 2019 Oct 4;20(10):e48115
EMBO reports 2019 Oct 4;20(10):e48115
Icariin improves the cognitive function of APP/PS1 mice via suppressing endoplasmic reticulum stress.
Li F, Zhang Y, Lu X, Shi J, Gong Q
Life sciences 2019 Oct 1;234:116739
Life sciences 2019 Oct 1;234:116739
Dihydroartemisinin attenuates alcoholic fatty liver through regulation of lipin-1 signaling.
Chen X, Bian M, Jin H, Lian N, Shao J, Zhang F, Zheng S
IUBMB life 2019 Nov;71(11):1740-1750
IUBMB life 2019 Nov;71(11):1740-1750
Niban protein regulates apoptosis in HK-2 cells via caspase-dependent pathway.
Tang S, Wang J, Liu J, Huang Y, Zhou Y, Yang S, Zhang W, Yang M, Zhang H
Renal failure 2019 Nov;41(1):455-466
Renal failure 2019 Nov;41(1):455-466
Adenoviral TMBIM6 vector attenuates ER-stress-induced apoptosis in a neonatal hypoxic-ischemic rat model.
Doycheva D, Xu N, Kaur H, Malaguit J, McBride DW, Tang J, Zhang JH
Disease models & mechanisms 2019 Nov 22;12(11)
Disease models & mechanisms 2019 Nov 22;12(11)
Structure-toxicity relationships of saturated and unsaturated free fatty acids for elucidating the lipotoxic effects in human EndoC-βH1 beta-cells.
Plötz T, von Hanstein AS, Krümmel B, Laporte A, Mehmeti I, Lenzen S
Biochimica et biophysica acta. Molecular basis of disease 2019 Nov 1;1865(11):165525
Biochimica et biophysica acta. Molecular basis of disease 2019 Nov 1;1865(11):165525
Protective effects of CXCR3/HO‑1 gene‑modified BMMSCs on damaged intestinal epithelial cells: Role of the p38‑MAPK signaling pathway.
Yin M, Shen Z, Yang L, Zheng W, Song H
International journal of molecular medicine 2019 May;43(5):2086-2102
International journal of molecular medicine 2019 May;43(5):2086-2102
FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.
Lindén M, Thomsen C, Grundevik P, Jonasson E, Andersson D, Runnberg R, Dolatabadi S, Vannas C, Luna Santamarίa M, Fagman H, Ståhlberg A, Åman P
EMBO reports 2019 May;20(5)
EMBO reports 2019 May;20(5)
FAM175B promotes apoptosis by inhibiting ATF4 ubiquitination in esophageal squamous cell carcinoma.
Zhao Y, Yu Y, Li H, Zhang Z, Guo S, Zhu S, Guo Q, Li P, Min L, Zhang S
Molecular oncology 2019 May;13(5):1150-1165
Molecular oncology 2019 May;13(5):1150-1165
Safety and enhanced immunostimulatory activity of the DRD2 antagonist ONC201 in advanced solid tumor patients with weekly oral administration.
Stein MN, Malhotra J, Tarapore RS, Malhotra U, Silk AW, Chan N, Rodriguez L, Aisner J, Aiken RD, Mayer T, Haffty BG, Newman JH, Aspromonte SM, Bommareddy PK, Estupinian R, Chesson CB, Sadimin ET, Li S, Medina DJ, Saunders T, Frankel M, Kareddula A, Damare S, Wesolowsky E, Gabel C, El-Deiry WS, Prabhu VV, Allen JE, Stogniew M, Oster W, Bertino JR, Libutti SK, Mehnert JM, Zloza A
Journal for immunotherapy of cancer 2019 May 22;7(1):136
Journal for immunotherapy of cancer 2019 May 22;7(1):136
Icariside II prevents hypertensive heart disease by alleviating endoplasmic reticulum stress via the PERK/ATF-4/CHOP signalling pathway in spontaneously hypertensive rats.
Wu Y, Yue Y, Fu S, Li Y, Wu D, Lv J, Yang D
The Journal of pharmacy and pharmacology 2019 Mar;71(3):400-407
The Journal of pharmacy and pharmacology 2019 Mar;71(3):400-407
A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.
Moss SM, Taylor IR, Ruggero D, Gestwicki JE, Shokat KM, Mukherjee S
Cell host & microbe 2019 Mar 13;25(3):454-462.e6
Cell host & microbe 2019 Mar 13;25(3):454-462.e6
Exosomes from Microglia Attenuate Photoreceptor Injury and Neovascularization in an Animal Model of Retinopathy of Prematurity.
Xu W, Wu Y, Hu Z, Sun L, Dou G, Zhang Z, Wang H, Guo C, Wang Y
Molecular therapy. Nucleic acids 2019 Jun 7;16:778-790
Molecular therapy. Nucleic acids 2019 Jun 7;16:778-790
Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability.
Fu Z, Liu F, Liu C, Jin B, Jiang Y, Tang M, Qi X, Guo X
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1428-1435
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1428-1435
A pectic polysaccharide from water decoction of Xinjiang Lycium barbarum fruit protects against intestinal endoplasmic reticulum stress.
Huang C, Yao R, Zhu Z, Pang D, Cao X, Feng B, Paulsen BS, Li L, Yin Z, Chen X, Jia R, Song X, Ye G, Luo Q, Chen Z, Zou Y
International journal of biological macromolecules 2019 Jun 1;130:508-514
International journal of biological macromolecules 2019 Jun 1;130:508-514
Metformin induces TPC-1 cell apoptosis through endoplasmic reticulum stress-associated pathways in vitro and in vivo.
Ye J, Qi L, Chen K, Li R, Song S, Zhou C, Zhai W
International journal of oncology 2019 Jul;55(1):331-339
International journal of oncology 2019 Jul;55(1):331-339
Knockdown of TM9SF4 boosts ER stress to trigger cell death of chemoresistant breast cancer cells.
Zhu Y, Xie M, Meng Z, Leung LK, Chan FL, Hu X, Chi K, Liu C, Yao X
Oncogene 2019 Jul;38(29):5778-5791
Oncogene 2019 Jul;38(29):5778-5791
Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na(+) and Ca(2+) handling.
Nie J, Duan Q, He M, Li X, Wang B, Zhou C, Wu L, Wen Z, Chen C, Wang DW, Alsina KM, Wehrens XHT, Wang DW, Ni L
Journal of cellular physiology 2019 Jul;234(7):11587-11601
Journal of cellular physiology 2019 Jul;234(7):11587-11601
Multi-walled carbon nanotubes promoted lipid accumulation in human aortic smooth muscle cells.
Yang H, Li J, Yang C, Liu H, Cao Y
Toxicology and applied pharmacology 2019 Jul 1;374:11-19
Toxicology and applied pharmacology 2019 Jul 1;374:11-19
Autophagy activation alleviates nonylphenol-induced apoptosis in cultured cortical neurons.
Li S, Jiang Z, Chai W, Xu Y, Wang Y
Neurochemistry international 2019 Jan;122:73-84
Neurochemistry international 2019 Jan;122:73-84
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
Hong J, Hu Z, Wu Q, Tang C, Hu J, Chen R, Li B, Wang Z
Bioscience reports 2019 Jan 31;39(1)
Bioscience reports 2019 Jan 31;39(1)
Endoplasmic Reticulum Stress Activated by Androgen Enhances Apoptosis of Granulosa Cells via Induction of Death Receptor 5 in PCOS.
Azhary JMK, Harada M, Takahashi N, Nose E, Kunitomi C, Koike H, Hirata T, Hirota Y, Koga K, Wada-Hiraike O, Fujii T, Osuga Y
Endocrinology 2019 Jan 1;160(1):119-132
Endocrinology 2019 Jan 1;160(1):119-132
Pterostilbene exerts a protective effect via regulating tunicamycin-induced endoplasmic reticulum stress in mouse preimplantation embryos.
Ullah O, Li Z, Ali I, Xu L, Liu H, Jin HZ, Fang YY, Jin QG, Fang N
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
In vitro cellular & developmental biology. Animal 2019 Feb;55(2):82-93
Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, Liu K, Liu X, Sun H
Inflammation 2019 Feb;42(1):64-80
Inflammation 2019 Feb;42(1):64-80
Mesencephalic astrocyte-derived neurotrophic factor (MANF) protects against Aβ toxicity via attenuating Aβ-induced endoplasmic reticulum stress.
Xu S, Di Z, He Y, Wang R, Ma Y, Sun R, Li J, Wang T, Shen Y, Fang S, Feng L, Shen Y
Journal of neuroinflammation 2019 Feb 13;16(1):35
Journal of neuroinflammation 2019 Feb 13;16(1):35
Chronic intermittent hypoxia accelerates liver fibrosis in rats with combined hypoxia and nonalcoholic steatohepatitis via angiogenesis rather than endoplasmic reticulum stress.
Wu W, Li W, Wei J, Wang C, Yao Y, Zhu W, He W, Zhou W, Liu J
Acta biochimica et biophysica Sinica 2019 Feb 1;51(2):159-167
Acta biochimica et biophysica Sinica 2019 Feb 1;51(2):159-167
Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.
Hu J, Wu Q, Wang Z, Hong J, Chen R, Li B, Hu Z, Hu X, Zhang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109475
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Dec;120:109475
Signaling from mTOR to eIF2α mediates cell migration in response to the chemotherapeutic doxorubicin.
Harvey RF, Pöyry TAA, Stoneley M, Willis AE
Science signaling 2019 Dec 17;12(612)
Science signaling 2019 Dec 17;12(612)
Bone marrow mesenchymal stem cells could reduce the toxic effects of hexavalent chromium on the liver by decreasing endoplasmic reticulum stress-mediated apoptosis via SIRT1/HIF-1α signaling pathway in rats.
Zhao Y, Yan J, Li AP, Zhang ZL, Li ZR, Guo KJ, Zhao KC, Ruan Q, Guo L
Toxicology letters 2019 Aug;310:31-38
Toxicology letters 2019 Aug;310:31-38
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Li SS, Jiang WL, Xiao WQ, Li K, Zhang YF, Guo XY, Dai YQ, Zhao QY, Jiang MJ, Lu ZJ, Wan R
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
Protective effect of curcumin against irinotecan‑induced intestinal mucosal injury via attenuation of NF‑κB activation, oxidative stress and endoplasmic reticulum stress.
Ouyang M, Luo Z, Zhang W, Zhu D, Lu Y, Wu J, Yao X
International journal of oncology 2019 Apr;54(4):1376-1386
International journal of oncology 2019 Apr;54(4):1376-1386
Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice.
Gu M, Zhao P, Zhang S, Fan S, Yang L, Tong Q, Ji G, Huang C
British journal of pharmacology 2019 Apr;176(7):847-863
British journal of pharmacology 2019 Apr;176(7):847-863
20(S)-protopanaxadiol induces apoptosis in human umbilical vein endothelial cells by activating the PERK-eIF2alpha-ATF4 signaling pathway.
Wang X, Xia HY, Qin HY, Kang XP, Hu HY, Zheng J, Jiang JY, Yao LA, Xu YW, Zhang T, Zhang XL
Journal of cellular biochemistry 2019 Apr;120(4):5085-5096
Journal of cellular biochemistry 2019 Apr;120(4):5085-5096
TMEM30A deficiency in endothelial cells impairs cell proliferation and angiogenesis.
Zhang S, Liu W, Yang Y, Sun K, Li S, Xu H, Yang M, Zhang L, Zhu X
Journal of cell science 2019 Apr 3;132(7)
Journal of cell science 2019 Apr 3;132(7)
Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture.
Duan YM, Jin Y, Guo ML, Duan LX, Wang JG
Journal of Cancer 2018;9(15):2723-2733
Journal of Cancer 2018;9(15):2723-2733
MnTMPyP inhibits paraquat-induced pulmonary epithelial-like cell injury by inhibiting oxidative stress.
Xu Y, Sun D, Song C, Wang R, Dong X
The Journal of toxicological sciences 2018;43(9):545-555
The Journal of toxicological sciences 2018;43(9):545-555
A comparative study of toxicity of TiO(2), ZnO, and Ag nanoparticles to human aortic smooth-muscle cells.
Wang M, Yang Q, Long J, Ding Y, Zou X, Liao G, Cao Y
International journal of nanomedicine 2018;13:8037-8049
International journal of nanomedicine 2018;13:8037-8049
Apoptosis of bone marrow mesenchymal stromal/stem cells via the MAPK and endoplasmic reticulum stress signaling pathways.
Chen T, Zhu H, Wang Y, Zhao P, Chen J, Sun J, Zhang X, Zhu G
American journal of translational research 2018;10(8):2555-2566
American journal of translational research 2018;10(8):2555-2566
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Tan N, Li X, Zhai L, Liu D, Li J, Yokota H, Zhang P
Hepatology research : the official journal of the Japan Society of Hepatology 2018 Sep;48(10):839-849
Hepatology research : the official journal of the Japan Society of Hepatology 2018 Sep;48(10):839-849
TMCO1 is essential for ovarian follicle development by regulating ER Ca(2+) store of granulosa cells.
Sun Z, Zhang H, Wang X, Wang QC, Zhang C, Wang JQ, Wang YH, An CQ, Yang KY, Wang Y, Gao F, Guo C, Tang TS
Cell death and differentiation 2018 Sep;25(9):1686-1701
Cell death and differentiation 2018 Sep;25(9):1686-1701
Ticagrelor protects against AngII-induced endothelial dysfunction by alleviating endoplasmic reticulum stress.
Wang X, Han X, Li M, Han Y, Zhang Y, Zhao S, Li Y
Microvascular research 2018 Sep;119:98-104
Microvascular research 2018 Sep;119:98-104
Benefits of combination low-dose pioglitazone plus fish oil on aged type 2 diabetes mice.
Iizuka Y, Kim H, Hirako S, Chiba K, Wada M, Matsumoto A
Journal of food and drug analysis 2018 Oct;26(4):1265-1274
Journal of food and drug analysis 2018 Oct;26(4):1265-1274
ERp44 depletion exacerbates ER stress and aggravates diabetic nephropathy in db/db mice.
Pang X, Zhang Y, Shi X, Li D, Han J
Biochemical and biophysical research communications 2018 Oct 12;504(4):921-926
Biochemical and biophysical research communications 2018 Oct 12;504(4):921-926
Nordihydroguaiaretic Acid, a Lignan from Larrea tridentata (Creosote Bush), Protects Against American Lifestyle-Induced Obesity Syndrome Diet-Induced Metabolic Dysfunction in Mice.
Chan JKW, Bittner S, Bittner A, Atwal S, Shen WJ, Inayathullah M, Rajada J, Nicolls MR, Kraemer FB, Azhar S
The Journal of pharmacology and experimental therapeutics 2018 May;365(2):281-290
The Journal of pharmacology and experimental therapeutics 2018 May;365(2):281-290
Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78.
Cai Y, Zheng Y, Gu J, Wang S, Wang N, Yang B, Zhang F, Wang D, Fu W, Wang Z
Cell death & disease 2018 May 25;9(6):636
Cell death & disease 2018 May 25;9(6):636
Effects of sevoflurane pretreatment on the apoptosis of rat H9c2 cardiomyocytes and the expression of GRP78.
Wang Z, Cui R, Wang K
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
Experimental and therapeutic medicine 2018 Mar;15(3):2818-2823
7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway.
Tsai TC, Lai KH, Su JH, Wu YJ, Sheu JH
Marine drugs 2018 Mar 26;16(4)
Marine drugs 2018 Mar 26;16(4)
18β-Glycyrrhetinic-acid-mediated unfolded protein response induces autophagy and apoptosis in hepatocellular carcinoma.
Chen J, Zhang ZQ, Song J, Liu QM, Wang C, Huang Z, Chu L, Liang HF, Zhang BX, Chen XP
Scientific reports 2018 Jun 19;8(1):9365
Scientific reports 2018 Jun 19;8(1):9365
TRPV6 protects ER stress-induced apoptosis via ATF6α-TRPV6-JNK pathway in human embryonic stem cell-derived cardiomyocytes.
Li Z, Meng Z, Lu J, Chen FM, Wong WT, Tse G, Zheng C, Keung W, Tse K, Li RA, Jiang L, Yao X
Journal of molecular and cellular cardiology 2018 Jul;120:1-11
Journal of molecular and cellular cardiology 2018 Jul;120:1-11
STF-083010, an inhibitor of XBP1 splicing, attenuates acute renal failure in rats by suppressing endoplasmic reticulum stress-induced apoptosis and inflammation.
Liu L, Xu L, Zhang S, Wang D, Dong G, Chen H, Li X, Shu C, Wang R
Experimental animals 2018 Jul 30;67(3):373-382
Experimental animals 2018 Jul 30;67(3):373-382
Dihydroartemisinin inhibits ER stress-mediated mitochondrial pathway to attenuate hepatocyte lipoapoptosis via blocking the activation of the PI3K/Akt pathway.
Chen X, Bian M, Zhang C, Kai J, Yao Z, Jin H, Lu C, Shao J, Chen A, Zhang F, Zheng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:975-984
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jan;97:975-984
Asiatic acid from Potentilla chinensis alleviates non-alcoholic fatty liver by regulating endoplasmic reticulum stress and lipid metabolism.
Wang D, Lao L, Pang X, Qiao Q, Pang L, Feng Z, Bai F, Sun X, Lin X, Wei J
International immunopharmacology 2018 Dec;65:256-267
International immunopharmacology 2018 Dec;65:256-267
Endoplasmic Reticulum Stress in the Dorsal Root Ganglion Contributes to the Development of Pain Hypersensitivity after Nerve Injury.
Yamaguchi Y, Oh-Hashi K, Matsuoka Y, Takemura H, Yamakita S, Matsuda M, Sawa T, Amaya F
Neuroscience 2018 Dec 1;394:288-299
Neuroscience 2018 Dec 1;394:288-299
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
Geng W, Qin F, Ren J, Xiao S, Wang A
Experimental cell research 2018 Aug 15;369(2):243-250
Experimental cell research 2018 Aug 15;369(2):243-250
CHOP induces apoptosis by affecting brain iron metabolism in rats with subarachnoid hemorrhage.
Zhao J, Xiang X, Zhang H, Jiang D, Liang Y, Qing W, Liu L, Zhao Q, He Z
Experimental neurology 2018 Apr;302:22-33
Experimental neurology 2018 Apr;302:22-33
Exogenous H(2)S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes.
Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, Wang Y, Wei C, Wang R, Wu L, Li H, Xu C
Cell & bioscience 2017;7:67
Cell & bioscience 2017;7:67
Transthyretin Exerts Pro-Apoptotic Effects in Human Retinal Microvascular Endothelial Cells Through a GRP78-Dependent Pathway in Diabetic Retinopathy.
Shao J, Yin Y, Yin X, Ji L, Xin Y, Zou J, Yao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(2):788-800
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;43(2):788-800
Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model.
Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H
Audiology & neuro-otology 2017;22(3):160-168
Audiology & neuro-otology 2017;22(3):160-168
Therapeutic effects of L-Cysteine in newborn mice subjected to hypoxia-ischemia brain injury via the CBS/H(2)S system: Role of oxidative stress and endoplasmic reticulum stress.
Liu S, Xin D, Wang L, Zhang T, Bai X, Li T, Xie Y, Xue H, Bo S, Liu D, Wang Z
Redox biology 2017 Oct;13:528-540
Redox biology 2017 Oct;13:528-540
Circular RNA HIPK2 regulates astrocyte activation via cooperation of autophagy and ER stress by targeting MIR124-2HG.
Huang R, Zhang Y, Han B, Bai Y, Zhou R, Gan G, Chao J, Hu G, Yao H
Autophagy 2017 Oct 3;13(10):1722-1741
Autophagy 2017 Oct 3;13(10):1722-1741
Garcinol from Garcinia indica Downregulates Cancer Stem-like Cell Biomarker ALDH1A1 in Nonsmall Cell Lung Cancer A549 Cells through DDIT3 Activation.
Wang J, Wang L, Ho CT, Zhang K, Liu Q, Zhao H
Journal of agricultural and food chemistry 2017 May 10;65(18):3675-3683
Journal of agricultural and food chemistry 2017 May 10;65(18):3675-3683
Involvement of the activation of Nrf2/HO-1, p38 MAPK signaling pathways and endoplasmic reticulum stress in furazolidone induced cytotoxicity and S phase arrest in human hepatocyte L02 cells: modulation of curcumin.
Dai C, Lei L, Li B, Lin Y, Xiao X, Tang S
Toxicology mechanisms and methods 2017 Mar;27(3):165-172
Toxicology mechanisms and methods 2017 Mar;27(3):165-172
Identification of Novel SCIRR69-Interacting Proteins During ER Stress Using SILAC-Immunoprecipitation Quantitative Proteomics Approach.
Chen Y, Liu Y, Lin S, Yang S, Que H, Liu S
Neuromolecular medicine 2017 Mar;19(1):81-93
Neuromolecular medicine 2017 Mar;19(1):81-93
Exogenous H(2)S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes.
Yang F, Yu X, Li T, Wu J, Zhao Y, Liu J, Sun A, Dong S, Wu J, Zhong X, Xu C, Lu F, Zhang W
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
American journal of physiology. Endocrinology and metabolism 2017 Mar 1;312(3):E190-E203
Curcumin enhances the effects of irinotecan on colorectal cancer cells through the generation of reactive oxygen species and activation of the endoplasmic reticulum stress pathway.
Huang YF, Zhu DJ, Chen XW, Chen QK, Luo ZT, Liu CC, Wang GX, Zhang WJ, Liao NZ
Oncotarget 2017 Jun 20;8(25):40264-40275
Oncotarget 2017 Jun 20;8(25):40264-40275
Astragaloside IV attenuates free fatty acid-induced ER stress and lipid accumulation in hepatocytes via AMPK activation.
Zhou B, Zhou DL, Wei XH, Zhong RY, Xu J, Sun L
Acta pharmacologica Sinica 2017 Jul;38(7):998-1008
Acta pharmacologica Sinica 2017 Jul;38(7):998-1008
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
Liu J, Li M, Gong J, Han P, Wang Y, Li D, Tian D, Liao J
Biology open 2017 Jan 15;6(1):29-34
Biology open 2017 Jan 15;6(1):29-34
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
Jiang Y, Chen X, Fan M, Li H, Zhu W, Chen X, Cao C, Xu R, Wang Y, Ma Y
Molecular immunology 2017 Feb;82:123-136
Molecular immunology 2017 Feb;82:123-136
The reproductive toxicology of male SD rats after PM(2.5) exposure mediated by the stimulation of endoplasmic reticulum stress.
Liu X, Jin X, Su R, Li Z
Chemosphere 2017 Dec;189:547-555
Chemosphere 2017 Dec;189:547-555
Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats.
Liu M, Liu S, Tan W, Tang F, Long J, Li Z, Liang B, Chu C, Yang J
Molecular medicine reports 2017 Dec;16(6):8953-8963
Molecular medicine reports 2017 Dec;16(6):8953-8963
Role of endoplasmic reticulum stress in disuse osteoporosis.
Li J, Yang S, Li X, Liu D, Wang Z, Guo J, Tan N, Gao Z, Zhao X, Zhang J, Gou F, Yokota H, Zhang P
Bone 2017 Apr;97:2-14
Bone 2017 Apr;97:2-14
Oleate attenuates palmitate-induced endoplasmic reticulum stress and apoptosis in placental trophoblasts.
Colvin BN, Longtine MS, Chen B, Costa ML, Nelson DM
Reproduction (Cambridge, England) 2017 Apr;153(4):369-380
Reproduction (Cambridge, England) 2017 Apr;153(4):369-380
Dimethylarginine Dimethylaminohydrolase 1 Protects Against High-Fat Diet-Induced Hepatic Steatosis and Insulin Resistance in Mice.
Li T, Feng R, Zhao C, Wang Y, Wang J, Liu S, Cao J, Wang H, Wang T, Guo Y, Lu Z
Antioxidants & redox signaling 2017 Apr 10;26(11):598-609
Antioxidants & redox signaling 2017 Apr 10;26(11):598-609
Reduced expression of citrate synthase leads to excessive superoxide formation and cell apoptosis.
Cai Q, Zhao M, Liu X, Wang X, Nie Y, Li P, Liu T, Ge R, Han F
Biochemical and biophysical research communications 2017 Apr 1;485(2):388-394
Biochemical and biophysical research communications 2017 Apr 1;485(2):388-394
4-Phenylbutyric Acid Induces Protection against Pulmonary Arterial Hypertension in Rats.
Wu Y, Adi D, Long M, Wang J, Liu F, Gai MT, Aierken A, Li MY, Li Q, Wu LQ, Ma YT, Hujiaaihemaiti M
PloS one 2016;11(6):e0157538
PloS one 2016;11(6):e0157538
Hydrogen-rich saline mediates neuroprotection through the regulation of endoplasmic reticulum stress and autophagy under hypoxia-ischemia neonatal brain injury in mice.
Bai X, Liu S, Yuan L, Xie Y, Li T, Wang L, Wang X, Zhang T, Qin S, Song G, Ge L, Wang Z
Brain research 2016 Sep 1;1646:410-417
Brain research 2016 Sep 1;1646:410-417
Rifampicin-induced injury in L02 cells is alleviated by 4-PBA via inhibition of the PERK-ATF4-CHOP pathway.
Zhang W, Chen L, Shen Y, Xu J
Toxicology in vitro : an international journal published in association with BIBRA 2016 Oct;36:186-196
Toxicology in vitro : an international journal published in association with BIBRA 2016 Oct;36:186-196
Ablation of Perk in Schwann Cells Improves Myelination in the S63del Charcot-Marie-Tooth 1B Mouse.
Sidoli M, Musner N, Silvestri N, Ungaro D, D'Antonio M, Cavener DR, Feltri ML, Wrabetz L
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Nov 2;36(44):11350-11361
The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 Nov 2;36(44):11350-11361
Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs.
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, Sun H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 May;80:63-72
Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells.
Huang M, Xu A, Wu X, Zhang Y, Guo Y, Guo F, Pan Z, Kong L
Archives of virology 2016 Mar;161(3):699-703
Archives of virology 2016 Mar;161(3):699-703
Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway.
Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, Shi D
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Reproduction in domestic animals = Zuchthygiene 2016 Feb;51(1):75-84
Protective effects of fish oil and pioglitazone on pancreatic tissue in obese KK mice with type 2 diabetes.
Iizuka Y, Kim H, Izawa T, Sakurai K, Hirako S, Wada M, Matsumoto A
Prostaglandins, leukotrienes, and essential fatty acids 2016 Dec;115:53-59
Prostaglandins, leukotrienes, and essential fatty acids 2016 Dec;115:53-59
Resveratrol Induces Cancer Cell Apoptosis through MiR-326/PKM2-Mediated ER Stress and Mitochondrial Fission.
Wu H, Wang Y, Wu C, Yang P, Li H, Li Z
Journal of agricultural and food chemistry 2016 Dec 14;64(49):9356-9367
Journal of agricultural and food chemistry 2016 Dec 14;64(49):9356-9367
The protective effect of the earthworm active ingredients on hepatocellular injury induced by endoplasmic reticulum stress.
Wang Q, Duan LX, Xu ZS, Wang JG, Xi SM
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Aug;82:304-11
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Aug;82:304-11
Quinocetone triggered ER stress-induced autophagy via ATF6/DAPK1-modulated mAtg9a trafficking.
Zhou Y, Zhang S, Dai C, Tang S, Yang X, Li D, Zhao K, Xiao X
Cell biology and toxicology 2016 Apr;32(2):141-52
Cell biology and toxicology 2016 Apr;32(2):141-52
Beclin-1-independent autophagy mediates programmed cancer cell death through interplays with endoplasmic reticulum and/or mitochondria in colbat chloride-induced hypoxia.
Sun L, Liu N, Liu SS, Xia WY, Liu MY, Li LF, Gao JX
American journal of cancer research 2015;5(9):2626-42
American journal of cancer research 2015;5(9):2626-42
Evaluation of cytotoxic activity of titanocene difluorides and determination of their mechanism of action in ovarian cancer cells.
Koubkova L, Vyzula R, Karban J, Pinkas J, Ondrouskova E, Vojtesek B, Hrstka R
Investigational new drugs 2015 Oct;33(5):1123-32
Investigational new drugs 2015 Oct;33(5):1123-32
Endoplasmic reticulum stress is involved in the lidocaine-induced apoptosis in SH-SY5Y neuroblastoma cells.
Li K, Han X
Journal of molecular neuroscience : MN 2015 May;56(1):122-30
Journal of molecular neuroscience : MN 2015 May;56(1):122-30
Polychlorinated biphenyl quinone induces endoplasmic reticulum stress, unfolded protein response, and calcium release.
Xu D, Su C, Song X, Shi Q, Fu J, Hu L, Xia X, Song E, Song Y
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Chemical research in toxicology 2015 Jun 15;28(6):1326-37
Role of Endoplasmic Reticulum Stress in Brain Damage After Cardiopulmonary Resuscitation in Rats.
Zhang J, Xie X, Pan H, Wu Z, Lu W, Yang G
Shock (Augusta, Ga.) 2015 Jul;44(1):65-71
Shock (Augusta, Ga.) 2015 Jul;44(1):65-71
Inhibition of c-Src/p38 MAPK pathway ameliorates renal tubular epithelial cells apoptosis in db/db mice.
Wu H, Shi Y, Deng X, Su Y, Du C, Wei J, Ren Y, Wu M, Hou Y, Duan H
Molecular and cellular endocrinology 2015 Dec 5;417:27-35
Molecular and cellular endocrinology 2015 Dec 5;417:27-35
O-Alkylated derivatives of quercetin induce apoptosis of MCF-7 cells via a caspase-independent mitochondrial pathway.
Liao H, Bao X, Zhu J, Qu J, Sun Y, Ma X, Wang E, Guo X, Kang Q, Zhen Y
Chemico-biological interactions 2015 Dec 5;242:91-8
Chemico-biological interactions 2015 Dec 5;242:91-8
Normal and functional TP53 in genetically stable myxoid/round cell liposarcoma.
Ståhlberg A, Kåbjörn Gustafsson C, Engtröm K, Thomsen C, Dolatabadi S, Jonasson E, Li CY, Ruff D, Chen SM, Åman P
PloS one 2014;9(11):e113110
PloS one 2014;9(11):e113110
Down-regulation of PERK-ATF4-CHOP pathway by Astragaloside IV is associated with the inhibition of endoplasmic reticulum stress-induced podocyte apoptosis in diabetic rats.
Chen Y, Gui D, Chen J, He D, Luo Y, Wang N
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;33(6):1975-87
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2014;33(6):1975-87
Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants.
Zhang P, Gao K, Tang Y, Jin X, An J, Yu H, Wang H, Zhang Y, Wang D, Huang H, Yu L, Wang C
Human mutation 2014 Sep;35(9):1142-51
Human mutation 2014 Sep;35(9):1142-51
Protein degradation and quality control in cells from laforin and malin knockout mice.
Garyali P, Segvich DM, DePaoli-Roach AA, Roach PJ
The Journal of biological chemistry 2014 Jul 25;289(30):20606-14
The Journal of biological chemistry 2014 Jul 25;289(30):20606-14
Polydatin improves glucose and lipid metabolism in experimental diabetes through activating the Akt signaling pathway.
Hao J, Chen C, Huang K, Huang J, Li J, Liu P, Huang H
European journal of pharmacology 2014 Dec 15;745:152-65
European journal of pharmacology 2014 Dec 15;745:152-65
ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.
Xue J, Wei J, Dong X, Zhu C, Li Y, Song A, Liu Z
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44
Protein kinase RNA-like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)-mediated endoplasmic reticulum stress-induced apoptosis in diabetic cardiomyopathy.
Liu ZW, Zhu HT, Chen KL, Dong X, Wei J, Qiu C, Xue JH
Cardiovascular diabetology 2013 Nov 2;12:158
Cardiovascular diabetology 2013 Nov 2;12:158
Arsenic trioxide alleviates airway hyperresponsiveness and promotes apoptosis of CD4+ T lymphocytes: evidence for involvement of the ER stress-CHOP pathway.
Li K, Zhang L, Xiang X, Gong S, Ma L, Xu L, Wang G, Liu Y, Ji X, Liu S, Chen P, Zeng H, Li J
Irish journal of medical science 2013 Dec;182(4):573-83
Irish journal of medical science 2013 Dec;182(4):573-83
Selenium deficiency is associated with endoplasmic reticulum stress in a rat model of cardiac malfunction.
Wang SQ, Niu XL, Liu ZW, Zhu YH, Gao DF
Biological trace element research 2013 Dec;156(1-3):196-201
Biological trace element research 2013 Dec;156(1-3):196-201
Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity.
Li J, Liu K, Liu Y, Xu Y, Zhang F, Yang H, Liu J, Pan T, Chen J, Wu M, Zhou X, Yuan Z
Nature immunology 2013 Aug;14(8):793-803
Nature immunology 2013 Aug;14(8):793-803
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 15204-1-AP(CHOP; GADD153 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 15204-1-AP(CHOP; GADD153 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CHOP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CHOP. This antibody recognizes human,mouse,rat antigen. The CHOP antibody has been validated for the following applications: ELISA, WB, IHC analysis.
