Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN952423 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-DNA-Damage-Inducible Transcript 3 (DDIT3) (AA 81-110), (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of Human GADD153 / CHOP. Genename: DDIT3
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 81-110,Middle Region
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1.
Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression.
Repression of peroxisome proliferator-activated receptor gamma by mucosal ribotoxic insult-activated CCAAT/enhancer-binding protein homologous protein.
Zhang HM, Ye X, Su Y, Yuan J, Liu Z, Stein DA, Yang D
Journal of virology 2010 Sep;84(17):8446-59
Journal of virology 2010 Sep;84(17):8446-59
Endoplasmic reticulum stress-induced transcription factor, CHOP, is crucial for dendritic cell IL-23 expression.
Goodall JC, Wu C, Zhang Y, McNeill L, Ellis L, Saudek V, Gaston JS
Proceedings of the National Academy of Sciences of the United States of America 2010 Oct 12;107(41):17698-703
Proceedings of the National Academy of Sciences of the United States of America 2010 Oct 12;107(41):17698-703
Repression of peroxisome proliferator-activated receptor gamma by mucosal ribotoxic insult-activated CCAAT/enhancer-binding protein homologous protein.
Park SH, Choi HJ, Yang H, Do KH, Kim J, Moon Y
Journal of immunology (Baltimore, Md. : 1950) 2010 Nov 1;185(9):5522-30
Journal of immunology (Baltimore, Md. : 1950) 2010 Nov 1;185(9):5522-30
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of GADD153 / CHOP Antibody Cat.-No AP51212PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the DDIT3 antibody detected the DDIT3 protein (arrow).