orb2636822

antibody from Biorbyt
Targeting: GTF2H2C
Provider product page for orb2636822
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb2636822 - Provider product page
Provider
Biorbyt
Product name
GTF2H2C Antibody
Antibody type
Monoclonal
Description
Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-GTF2H2C-2C9
Vial size
100 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
GTF2H2C protein structure - orb2636822 shown in red.