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Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- HPA038299 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA038299, RRID:AB_10675793
- Product name
- Anti-TMEM165
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human TMEM165, Gene description: transmembrane protein 165, Alternative Gene Names: GDT1, TMPT27, TPARL, Validated applications: ICC, IHC, Uniprot ID: Q9HC07, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Syntaxin‐5's flexibility in SNARE pairing supports Golgi functions
New insights into the pathogenicity of TMEM165 variants using structural modeling based on AlphaFold 2 predictions
Acute COG complex inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra‐Golgi recycling vesicles
The Golgi-associated retrograde protein (GARP) complex plays an essential role in the maintenance of the Golgi glycosylation machinery
TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy.
Milk biosynthesis requires the Golgi cation exchanger TMEM165
TMEM165 Deficiency Causes a Congenital Disorder of Glycosylation
D'Souza Z, Pokrovskaya I, Lupashin V
Traffic 2023;24(8):355-379
Traffic 2023;24(8):355-379
New insights into the pathogenicity of TMEM165 variants using structural modeling based on AlphaFold 2 predictions
Legrand D, Herbaut M, Durin Z, Brysbaert G, Bardor M, Lensink M, Foulquier F
Computational and Structural Biotechnology Journal 2023;21
Computational and Structural Biotechnology Journal 2023;21
Acute COG complex inactivation unveiled its immediate impact on Golgi and illuminated the nature of intra‐Golgi recycling vesicles
Sumya F, Pokrovskaya I, D'Souza Z, Lupashin V
Traffic 2022;24(2):52-75
Traffic 2022;24(2):52-75
The Golgi-associated retrograde protein (GARP) complex plays an essential role in the maintenance of the Golgi glycosylation machinery
Khakurel A, Kudlyk T, Bonifacino J, Lupashin V, Glick B
Molecular Biology of the Cell 2021;32(17):1594-1610
Molecular Biology of the Cell 2021;32(17):1594-1610
TMEM165 a new player in proteoglycan synthesis: loss of TMEM165 impairs elongation of chondroitin- and heparan-sulfate glycosaminoglycan chains of proteoglycans and triggers early chondrocyte differentiation and hypertrophy.
Khan S, Sbeity M, Foulquier F, Barré L, Ouzzine M
Cell death & disease 2021 Dec 20;13(1):11
Cell death & disease 2021 Dec 20;13(1):11
Milk biosynthesis requires the Golgi cation exchanger TMEM165
Snyder N, Palmer M, Reinhardt T, Cunningham K
Journal of Biological Chemistry 2019;294(9):3181-3191
Journal of Biological Chemistry 2019;294(9):3181-3191
TMEM165 Deficiency Causes a Congenital Disorder of Glycosylation
Foulquier F, Amyere M, Jaeken J, Zeevaert R, Schollen E, Race V, Bammens R, Morelle W, Rosnoblet C, Legrand D, Demaegd D, Buist N, Cheillan D, Guffon N, Morsomme P, Annaert W, Freeze H, Van Schaftingen E, Vikkula M, Matthijs G
The American Journal of Human Genetics 2012;91(1):15-26
The American Journal of Human Genetics 2012;91(1):15-26
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human placenta and skeletal muscle tissues using HPA038299 antibody. Corresponding TMEM165 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
