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- Antigen structure
- References [2]
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- Product number
- ABIN2840591 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (AA 336-365), (Center) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 336-365, Center
- Antibody clone number
- RB2187
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells.
Shi XP, Tugusheva K, Bruce JE, Lucka A, Wu GX, Chen-Dodson E, Price E, Li Y, Xu M, Huang Q, Sardana MK, Hazuda DJ
The Journal of biological chemistry 2003 Jun 6;278(23):21286-94
The Journal of biological chemistry 2003 Jun 6;278(23):21286-94
Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells.
Basi G, Frigon N, Barbour R, Doan T, Gordon G, McConlogue L, Sinha S, Zeller M
The Journal of biological chemistry 2003 Aug 22;278(34):31512-20
The Journal of biological chemistry 2003 Aug 22;278(34):31512-20
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Supportive validation
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS
