ABIN492803

antibody from antibodies-online

Targeting: BACE2 AEPLC, ALP56, CEAP1, DRAP

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN492803

Provider

antibodies-online

Product name

anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (N-Term), (Isoform A) antibody

Antibody type

Polyclonal

Antigen

Synthetic peptides corresponding to BACE2A/C (401-4199-26) from N-terminal regions of BACE 2A protien

Description

Affinity chromatography

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

N-Term,Isoform A

Vial size

0.1 mg

Concentration

0.76 - 0.72 mg/mL

Storage

Store (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells.

Lahiri DK, Maloney B, Ge YW
Journal of molecular neuroscience : MN 2006;29(1):65-80

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BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome.

Sun X, He G, Song W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Jul;20(9):1369-76

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Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.

Spoelgen R, von Arnim CA, Thomas AV, Peltan ID, Koker M, Deng A, Irizarry MC, Andersen OM, Willnow TE, Hyman BT
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Jan 11;26(2):418-28