Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- ABIN492805 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-beta-Site APP-Cleaving Enzyme 2 (BACE2) (N-Term), (Isoform B) antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptides corresponding to positions: BACE2B (379-396) from N-terminal regions of BACE 2A protien, peptide sequences are unique to BACE 2B protein and are conserved in many species.
- Description
- Affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- N-Term,Isoform B
- Vial size
- 0.1 mg
- Concentration
- 0.9 - 0.71 mg/mL
- Storage
- Store (in aliquots) at -20°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells.
BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome.
Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
Lahiri DK, Maloney B, Ge YW
Journal of molecular neuroscience : MN 2006;29(1):65-80
Journal of molecular neuroscience : MN 2006;29(1):65-80
BACE2, as a novel APP theta-secretase, is not responsible for the pathogenesis of Alzheimer's disease in Down syndrome.
Sun X, He G, Song W
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Jul;20(9):1369-76
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006 Jul;20(9):1369-76
Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
Spoelgen R, von Arnim CA, Thomas AV, Peltan ID, Koker M, Deng A, Irizarry MC, Andersen OM, Willnow TE, Hyman BT
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Jan 11;26(2):418-28
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 Jan 11;26(2):418-28
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