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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 23226-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ATG2A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATG2A antibody (Cat. #23226-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references GBP2 enhances paclitaxel sensitivity in triple‑negative breast cancer by promoting autophagy in combination with ATG2 and inhibiting the PI3K/AKT/mTOR pathway.
ATG9A regulates the dissociation of recycling endosomes from microtubules to form liquid influenza A virus inclusions.
MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy.
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.
The autophagy protein ATG9A enables lipid mobilization from lipid droplets.
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
A conserved ATG2-GABARAP family interaction is critical for phagophore formation.
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
Zhang W, Tang X, Peng Y, Xu Y, Liu L, Liu S
International journal of oncology 2024 Apr;64(4)
International journal of oncology 2024 Apr;64(4)
ATG9A regulates the dissociation of recycling endosomes from microtubules to form liquid influenza A virus inclusions.
Vale-Costa S, Etibor TA, Brás D, Sousa AL, Ferreira M, Martins GG, Mello VH, Amorim MJ
PLoS biology 2023 Nov;21(11):e3002290
PLoS biology 2023 Nov;21(11):e3002290
MGCG regulates glioblastoma tumorigenicity via hnRNPK/ATG2A and promotes autophagy.
Chu F, Wu P, Mu M, Hu S, Niu C
Cell death & disease 2023 Jul 17;14(7):443
Cell death & disease 2023 Jul 17;14(7):443
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy.
Cross J, Durgan J, McEwan DG, Tayler M, Ryan KM, Florey O
The Journal of cell biology 2023 Dec 4;222(12)
The Journal of cell biology 2023 Dec 4;222(12)
A phosphoinositide signalling pathway mediates rapid lysosomal repair.
Tan JX, Finkel T
Nature 2022 Sep;609(7928):815-821
Nature 2022 Sep;609(7928):815-821
ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation.
van Vliet AR, Chiduza GN, Maslen SL, Pye VE, Joshi D, De Tito S, Jefferies HBJ, Christodoulou E, Roustan C, Punch E, Hervás JH, O'Reilly N, Skehel JM, Cherepanov P, Tooze SA
Molecular cell 2022 Nov 17;82(22):4324-4339.e8
Molecular cell 2022 Nov 17;82(22):4324-4339.e8
The autophagy protein ATG9A enables lipid mobilization from lipid droplets.
Mailler E, Guardia CM, Bai X, Jarnik M, Williamson CD, Li Y, Maio N, Golden A, Bonifacino JS
Nature communications 2021 Nov 19;12(1):6750
Nature communications 2021 Nov 19;12(1):6750
ATG9A protects the plasma membrane from programmed and incidental permeabilization.
Claude-Taupin A, Jia J, Bhujabal Z, Garfa-Traoré M, Kumar S, da Silva GPD, Javed R, Gu Y, Allers L, Peters R, Wang F, da Costa LJ, Pallikkuth S, Lidke KA, Mauthe M, Verlhac P, Uchiyama Y, Salemi M, Phinney B, Tooze SA, Mari MC, Johansen T, Reggiori F, Deretic V
Nature cell biology 2021 Aug;23(8):846-858
Nature cell biology 2021 Aug;23(8):846-858
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
Sun W, Li J, Zhou L, Han J, Liu R, Zhang H, Ning T, Gao Z, Liu B, Chen X, Ba Y
Theranostics 2020;10(5):1981-1996
Theranostics 2020;10(5):1981-1996
A conserved ATG2-GABARAP family interaction is critical for phagophore formation.
Bozic M, van den Bekerom L, Milne BA, Goodman N, Roberston L, Prescott AR, Macartney TJ, Dawe N, McEwan DG
EMBO reports 2020 Mar 4;21(3):e48412
EMBO reports 2020 Mar 4;21(3):e48412
Fine particulate matter inhibits phagocytosis of macrophages by disturbing autophagy.
Li Y, Yong YL, Yang M, Wang W, Qu X, Dang X, Shang D, Shao Y, Liu J, Chang Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Dec;34(12):16716-16735
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 23226-1-AP( ATG2A Antibody) at dilution of 1:300
- Other comments
- WB
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ATG2A antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ATG2A. This antibody recognizes human antigen. The ATG2A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 23226-1-AP( ATG2A Antibody) at dilution of 1:50 (under 10x lens)
- Other comments
- IHC
