FNab00960

antibody from FineTest Biotech
Targeting: BRMS1 DKFZP564A063
Provider product page for FNab00960
Western blot
ELISA

Antibody data

Product number
FNab00960 - Provider product page
Provider
FineTest Biotech
Product name
BRMS1 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
breast cancer metastasis suppressor
1
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
BRMS1 protein structure - FNab00960 shown in red.