Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN967710 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cortactin (CTTN) antibody
- Antibody type
- Monoclonal
- Antigen
- Chicken Cortactin
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Chicken/Avian
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- OPG-13
- Vial size
- 150 μg
- Concentration
- 250 μg/ml
- Storage
- -20°C
Submitted references Adenovirus E4 open reading frame 4-induced apoptosis involves dysregulation of Src family kinases.
Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia.
Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway.
Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.
Identification and characterization of a novel cytoskeleton-associated pp60src substrate.
Lavoie JN, Champagne C, Gingras MC, Robert A
The Journal of cell biology 2000 Sep 4;150(5):1037-56
The Journal of cell biology 2000 Sep 4;150(5):1037-56
Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia.
Nakahara H, Mueller SC, Nomizu M, Yamada Y, Yeh Y, Chen WT
The Journal of biological chemistry 1998 Jan 2;273(1):9-12
The Journal of biological chemistry 1998 Jan 2;273(1):9-12
Invasion of epithelial cells by Shigella flexneri induces tyrosine phosphorylation of cortactin by a pp60c-src-mediated signalling pathway.
Dehio C, Prévost MC, Sansonetti PJ
The EMBO journal 1995 Jun 1;14(11):2471-82
The EMBO journal 1995 Jun 1;14(11):2471-82
Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex.
Wu H, Parsons JT
The Journal of cell biology 1993 Mar;120(6):1417-26
The Journal of cell biology 1993 Mar;120(6):1417-26
Identification and characterization of a novel cytoskeleton-associated pp60src substrate.
Wu H, Reynolds AB, Kanner SB, Vines RR, Parsons JT
Molecular and cellular biology 1991 Oct;11(10):5113-24
Molecular and cellular biology 1991 Oct;11(10):5113-24
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