Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11381-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11381-1-AP, RRID:AB_2088125
- Product name
- Cortactin antibody
- Antibody type
- Polyclonal
- Description
- Cortactin antibody (Cat. #11381-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Effects of Cortactin Expression on Prognosis in Patients with Breast Cancer.
Fiber Microarchitecture in Interpenetrating Collagen-Alginate Hydrogel with Tunable Mechanical Plasticity Regulates Tumor Cell Migration.
Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein.
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
ERRĪ± Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
CTTN Overexpression Confers Cancer Stem Cell-like Properties and Trastuzumab Resistance via DKK-1/WNT Signaling in HER2 Positive Breast Cancer.
Gab1 regulates invadopodia and autocrine VEGF through SHP2/ERK1/2 in hilar cholangiocarcinoma cells.
A four oxidative stress gene prognostic model and integrated immunity-analysis in pancreatic adenocarcinoma.
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Decreased expression of cortactin in the schizophrenia brain.
Zhang M, Cai F, Guo J, Liu S, Ma G, Cai M, Zhang R, Deng J
Cell death & disease 2024 Apr 26;15(4):297
Cell death & disease 2024 Apr 26;15(4):297
Effects of Cortactin Expression on Prognosis in Patients with Breast Cancer.
Son H, Jee S, Cha H, Song K, Bang S, Kim H, Paik S, Park H, Myung J
Diagnostics (Basel, Switzerland) 2023 Sep 7;13(18)
Diagnostics (Basel, Switzerland) 2023 Sep 7;13(18)
Fiber Microarchitecture in Interpenetrating Collagen-Alginate Hydrogel with Tunable Mechanical Plasticity Regulates Tumor Cell Migration.
Wei Z, Liu J, Jia Y, Lei M, Zhang S, Xi P, Ma Y, Zhang M, Ma J, Wang L, Guo H, Xu F
Advanced healthcare materials 2023 Nov;12(29):e2301586
Advanced healthcare materials 2023 Nov;12(29):e2301586
Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein.
Norris ML, Mendell JT
Genes & development 2023 Mar 1;37(5-6):191-203
Genes & development 2023 Mar 1;37(5-6):191-203
Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma.
Wang J, Huang TJ, Mei Y, Luo FF, Xie DH, Peng LX, Liu BQ, Fan ML, Zhang JB, Zheng ST, Qian CN, Huang BJ
Cancer gene therapy 2023 Feb;30(2):375-387
Cancer gene therapy 2023 Feb;30(2):375-387
ERRĪ± Up-Regulates Invadopodia Formation by Targeting HMGCS1 to Promote Endometrial Cancer Invasion and Metastasis.
Tang S, Ma J, Su P, Lei H, Tong Y, Cai L, Xu S, Mao X, Sun P
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
CTTN Overexpression Confers Cancer Stem Cell-like Properties and Trastuzumab Resistance via DKK-1/WNT Signaling in HER2 Positive Breast Cancer.
Moon SJ, Choi HJ, Kye YH, Jeong GY, Kim HY, Myung JK, Kong G
Cancers 2023 Feb 11;15(4)
Cancers 2023 Feb 11;15(4)
Gab1 regulates invadopodia and autocrine VEGF through SHP2/ERK1/2 in hilar cholangiocarcinoma cells.
Li T, Tian Y, Ren W, Chen P, Luo M, Sang H
American journal of translational research 2022;14(12):8934-8946
American journal of translational research 2022;14(12):8934-8946
A four oxidative stress gene prognostic model and integrated immunity-analysis in pancreatic adenocarcinoma.
Wang H, Tian RF, Liang X, Fan J, Duan ZC, Fan XY, Zhang JJ, Yao DS, Chen ZN, Li L
Frontiers in oncology 2022;12:1015042
Frontiers in oncology 2022;12:1015042
TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis.
Huang Q, Wu D, Zhao J, Yan Z, Chen L, Guo S, Wang D, Yuan C, Wang Y, Liu X, Xing J
The EMBO journal 2022 Jun 1;41(11):e110324
The EMBO journal 2022 Jun 1;41(11):e110324
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Huang C, Ou R, Chen X, Zhang Y, Li J, Liang Y, Zhu X, Liu L, Li M, Lin D, Qiu J, Liu G, Zhang L, Wu Y, Tang H, Liu Y, Liang L, Ding Y, Liao W
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Hypermethylation of UCHL1 Promotes Metastasis of Nasopharyngeal Carcinoma by Suppressing Degradation of Cortactin (CTTN).
Zhao Y, Lei Y, He SW, Li YQ, Wang YQ, Hong XH, Liang YL, Li JY, Chen Y, Luo WJ, Zhang PP, Yang XJ, He QM, Ma J, Liu N, Tang LL
Cells 2020 Feb 27;9(3)
Cells 2020 Feb 27;9(3)
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
Bo H, Fan L, Li J, Liu Z, Zhang S, Shi L, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B, Li X, Li G, Xiong W, Zeng Z, Xiong F, Gong Z
Journal of Cancer 2018;9(24):4677-4683
Journal of Cancer 2018;9(24):4677-4683
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Ma D, Zheng B, Suzuki T, Zhang R, Jiang C, Bai D, Yin W, Yang Z, Zhang X, Hou L, Zhan H, Wen JK
Circulation research 2017 Mar 3;120(5):799-815
Circulation research 2017 Mar 3;120(5):799-815
Decreased expression of cortactin in the schizophrenia brain.
Bhambhvani HP, Simmons M, Haroutunian V, Meador-Woodruff JH
Neuroreport 2016 Feb 10;27(3):145-50
Neuroreport 2016 Feb 10;27(3):145-50
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11381-1-AP(CTTN antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CTTN antibody 11381-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11381-1-AP(CTTN antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cortactin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cortactin. This antibody recognizes human,mouse,rat antigen. The Cortactin antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
