Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN362959 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Cortactin (CTTN) (AA 464-468) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around AA 464-468 (P-V-Y-E-T) derived from Human CORTACTIN. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 464-468
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references Involvement of dynamin-2 in formation of discoid vesicles in urinary bladder umbrella cells.
CXCL12 induces tyrosine phosphorylation of cortactin, which plays a role in CXC chemokine receptor 4-mediated extracellular signal-regulated kinase activation and chemotaxis.
Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion.
Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton.
Tyrosine phosphorylation of cortactin is required for H2O2-mediated injury of human endothelial cells.
Terada N, Ohno N, Saitoh S, Saitoh Y, Fujii Y, Kondo T, Katoh R, Chan C, Abraham SN, Ohno S
Cell and tissue research 2009 Jul;337(1):91-102
Cell and tissue research 2009 Jul;337(1):91-102
CXCL12 induces tyrosine phosphorylation of cortactin, which plays a role in CXC chemokine receptor 4-mediated extracellular signal-regulated kinase activation and chemotaxis.
Luo C, Pan H, Mines M, Watson K, Zhang J, Fan GH
The Journal of biological chemistry 2006 Oct 6;281(40):30081-93
The Journal of biological chemistry 2006 Oct 6;281(40):30081-93
Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion.
Kinley AW, Weed SA, Weaver AM, Karginov AV, Bissonette E, Cooper JA, Parsons JT
Current biology : CB 2003 Mar 4;13(5):384-93
Current biology : CB 2003 Mar 4;13(5):384-93
Cortactin tyrosine phosphorylation requires Rac1 activity and association with the cortical actin cytoskeleton.
Head JA, Jiang D, Li M, Zorn LJ, Schaefer EM, Parsons JT, Weed SA
Molecular biology of the cell 2003 Aug;14(8):3216-29
Molecular biology of the cell 2003 Aug;14(8):3216-29
Tyrosine phosphorylation of cortactin is required for H2O2-mediated injury of human endothelial cells.
Li Y, Liu J, Zhan X
The Journal of biological chemistry 2000 Nov 24;275(47):37187-93
The Journal of biological chemistry 2000 Nov 24;275(47):37187-93
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