ABIN965920

antibody from antibodies-online

Targeting: CTTN EMS1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN965920

Provider

antibodies-online

Product name

anti-Cortactin (CTTN) (pTyr466) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from mouse Cortactin around the phosphorylation site of tyrosine 466 (P-V-YP-E-T).

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pTyr466

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

CXCL12 induces tyrosine phosphorylation of cortactin, which plays a role in CXC chemokine receptor 4-mediated extracellular signal-regulated kinase activation and chemotaxis.

Luo C, Pan H, Mines M, Watson K, Zhang J, Fan GH
The Journal of biological chemistry 2006 Oct 6;281(40):30081-93

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Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion.

Kinley AW, Weed SA, Weaver AM, Karginov AV, Bissonette E, Cooper JA, Parsons JT
Current biology : CB 2003 Mar 4;13(5):384-93