BMS1035

antibody from Invitrogen Antibodies

Targeting: FASLG APT1LG1, CD178, FasL, TNFSF6

ELISA (Recommended by provider)

Flow cytometry (Recommended by provider)

Other assay (Recommended by provider)

Antibody Data

Product number

BMS1035

Provider

Invitrogen Antibodies

Product name

CD178 (Fas Ligand) Monoclonal Antibody (10F2), eBioscience™

Antibody type

Monoclonal

Antigen

Other

Description

Description: FasL is a member of the TNF family and is expressed by neutrophils, monocytes, and activated T cells and NK cells. The interaction of FasL with its receptor (CD95, Fas) induces Fas-mediated killing of lymphocytes. Human FasL is cleaved from the surface by matrix metalloproteinases (MMPs), resulting in a 26 kDa soluble form. Therefore for optimal detection of surface FasL on activated peripheral blood cells, incubation of cells with an MMP inhibitor is recommended. Applications Tested: ELISA, Flow Cytometry, Functional Studies (Blocking).

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

10F2

Vial size

100 µg

Concentration

1 mg/mL

Storage

-20°C