ABIN1981904

antibody from antibodies-online

Targeting: FASLG APT1LG1, CD178, FasL, TNFSF6

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Flow cytometry (Supportive data in Antibodypedia)

Functional assay (Recommended by provider)

Antibody Data

Product number

ABIN1981904

Provider

antibodies-online

Product name

anti-Fas Ligand (TNF Superfamily, Member 6) (FASL) antibody (PE)

Antibody type

Monoclonal

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Isotype

IgG

Antibody clone number

NOK-1

Vial size

100 tests

Storage

Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.

Handling

Do not freeze. Avoid prolonged exposure to light.Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

References

Submitted references

Apoptosis induced in HIV-1-exposed, resting CD4+ T cells subsequent to signaling through homing receptors is Fas/Fas ligand-mediated.

Ji J, Chen JJ, Braciale VL, Cloyd MW
Journal of leukocyte biology 2007 Jan;81(1):297-305

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Fas ligand (CD178) cytoplasmic tail is a positive regulator of Fas ligand-mediated cytotoxicity.

Jodo S, Pidiyar VJ, Xiao S, Furusaki A, Sharma R, Koike T, Ju ST
Journal of immunology (Baltimore, Md. : 1950) 2005 Apr 15;174(8):4470-4

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Human urinary bladder transitional cell carcinomas acquire the functional Fas ligand during tumor progression.

Chopin D, Barei-Moniri R, Maillé P, Le Frère-Belda MA, Muscatelli-Groux B, Merendino N, Lecerf L, Stoppacciaro A, Velotti F
The American journal of pathology 2003 Apr;162(4):1139-49

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Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178).

Ghadimi MP, Sanzenbacher R, Thiede B, Wenzel J, Jing Q, Plomann M, Borkhardt A, Kabelitz D, Janssen O
FEBS letters 2002 May 22;519(1-3):50-8

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Metalloproteinase-mediated release of human Fas ligand.

Kayagaki N, Kawasaki A, Ebata T, Ohmoto H, Ikeda S, Inoue S, Yoshino K, Okumura K, Yagita H
The Journal of experimental medicine 1995 Dec 1;182(6):1777-83

Flow cytometry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

FACS