Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx015799 - Provider product page
- Provider
- Abbexa
- Product name
- Myeloid Cell Surface Antigen CD33 (CD33) Antibody
- Antibody type
- Monoclonal
- Description
- The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells.Preferentially binds to alpha-2,6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules.Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD).
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 1 mg/ml
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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