AF-279-NA
antibody from Novus Biologicals
Targeting: CCL2
GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Blocking/Neutralizing [1]
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Validation data
Reference
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- Product number
- AF-279-NA - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal CCL2/JE/MCP-1 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human CCL2/JE/MCP-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant canine MCP-1 is observed and less than 5% cross-reactivity with recombinant mouse MCP-1, recombinant rat MCP-1, recombinant human (rh) Eotaxin, rhMCP-2 and rhMCP-4 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Teneligliptin prevents doxorubicin-induced inflammation and apoptosis in H9c2 cells.
Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination.
Fractalkine is a novel human adipochemokine associated with type 2 diabetes.
Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotype.
Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression.
Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol diet.
A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2.
Alterations in expression of monocyte chemotactic protein-1 in the simian immunodeficiency virus model of disseminated Mycobacterium avium complex.
Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbits.
Peng W, Rao D, Zhang M, Shi Y, Wu J, Nie G, Xia Q
Archives of biochemistry and biophysics 2020 Apr 15;683:108238
Archives of biochemistry and biophysics 2020 Apr 15;683:108238
Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination.
Zhan Z, Xie X, Cao H, Zhou X, Zhang XD, Fan H, Liu Z
Autophagy 2014 Feb;10(2):257-68
Autophagy 2014 Feb;10(2):257-68
Fractalkine is a novel human adipochemokine associated with type 2 diabetes.
Shah R, Hinkle CC, Ferguson JF, Mehta NN, Li M, Qu L, Lu Y, Putt ME, Ahima RS, Reilly MP
Diabetes 2011 May;60(5):1512-8
Diabetes 2011 May;60(5):1512-8
Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotype.
Ouwehand K, Oosterhoff D, Breetveld M, Scheper RJ, de Gruijl TD, Gibbs S
The Journal of investigative dermatology 2011 Feb;131(2):418-25
The Journal of investigative dermatology 2011 Feb;131(2):418-25
Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression.
Fujimoto H, Sangai T, Ishii G, Ikehara A, Nagashima T, Miyazaki M, Ochiai A
International journal of cancer 2009 Sep 15;125(6):1276-84
International journal of cancer 2009 Sep 15;125(6):1276-84
Interleukin-18 predicts atherosclerosis progression in SIV-infected and uninfected rhesus monkeys (Macaca mulatta) on a high-fat/high-cholesterol diet.
Yearley JH, Xia D, Pearson CB, Carville A, Shannon RP, Mansfield KG
Laboratory investigation; a journal of technical methods and pathology 2009 Jun;89(6):657-67
Laboratory investigation; a journal of technical methods and pathology 2009 Jun;89(6):657-67
A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
Arthritis and rheumatism 2008 Nov;58(11):3510-9
Arthritis and rheumatism 2008 Nov;58(11):3510-9
Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes.
Chou SY, Weng JY, Lai HL, Liao F, Sun SH, Tu PH, Dickson DW, Chern Y
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Mar 26;28(13):3277-90
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008 Mar 26;28(13):3277-90
Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2.
Metelitsa LS, Wu HW, Wang H, Yang Y, Warsi Z, Asgharzadeh S, Groshen S, Wilson SB, Seeger RC
The Journal of experimental medicine 2004 May 3;199(9):1213-21
The Journal of experimental medicine 2004 May 3;199(9):1213-21
Alterations in expression of monocyte chemotactic protein-1 in the simian immunodeficiency virus model of disseminated Mycobacterium avium complex.
Hendricks EE, Lin KC, Boisvert K, Pauley D, Mansfield KG
The Journal of infectious diseases 2004 May 1;189(9):1714-20
The Journal of infectious diseases 2004 May 1;189(9):1714-20
Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbits.
Ohtani K, Egashira K, Usui M, Ishibashi M, Hiasa KI, Zhao Q, Aoki M, Kaneda Y, Morishita R, Takeshita A
Gene therapy 2004 Jan;11(2):126-32
Gene therapy 2004 Jan;11(2):126-32
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Recombinant Human CCL2/JE/MCP-1 by Western Blot. Detection of Recombinant Human CCL2/JE/MCP-1 by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- CCL2/JE/MCP-1 in Human Crohn's Disease Intestine. CCL2/JE/MCP-1 in Human Crohn's Disease Intestine.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Chemotaxis Induced by CCL2/MCP-1 and Neutral-ization by Human CCL2/ MCP-1 Antibody. Chemotaxis Induced by CCL2/MCP-1 and Neutral-ization by Human CCL2/ MCP-1 Antibody.