25542-1-AP

antibody from Proteintech Group

Targeting: CCL2 GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF

Provider product page for 25542-1-AP

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ELISA

Immunocytochemistry

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [31]
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Product number: 25542-1-AP - Provider product page
Provider: Proteintech Group
Product name: MCP1 antibody
Antibody type: Polyclonal
Description: MCP1 antibody (Cat. #25542-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CCL2 protein structure - 25542-1-AP shown in red.

Submitted references Avoiding Absolute Quantification Trap: A Novel Predictive Signature of Clinical Benefit to Anti-PD-1 Immunotherapy in Non-Small Cell Lung Cancer.

Liu C, Wang S, Zheng S, Xu F, Cao Z, Feng X, Wang Y, Xue Q, Sun N, He J
Frontiers in immunology 2021;12:782106

CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis.

Li X, Tang X, Wang Y, Chai C, Zhao Z, Zhang H, Peng Y, Wu L
Frontiers in pharmacology 2021;12:655101

Potential Role of Macrophage Phenotypes and CCL2 in the Pathogenesis of Takayasu Arteritis.

Kong X, Xu M, Cui X, Ma L, Cheng H, Hou J, Sun X, Ma L, Jiang L
Frontiers in immunology 2021;12:646516

Macrophage targeted theranostic strategy for accurate detection and rapid stabilization of the inflamed high-risk plaque.

Song JW, Nam HS, Ahn JW, Park HS, Kang DO, Kim HJ, Kim YH, Han J, Choi JY, Lee SY, Kim S, Oh WY, Yoo H, Park K, Kim JW
Theranostics 2021;11(18):8874-8893

HSP47 contributes to angiogenesis by induction of CCL2 in bladder cancer.

Ma W, Ou T, Cui X, Wu K, Li H, Li Y, Peng G, Xia W, Wu S
Cellular signalling 2021 Sep;85:110044

Deficiency of tenascin-C attenuated cardiac injury by inactivating TLR4/NLRP3/caspase-1 pathway after myocardial infarction.

Xu M, Ye Z, Zhao X, Guo H, Gong X, Huang R
Cellular signalling 2021 Oct;86:110084

Effect of Freshly Isolated Bone Marrow Mononuclear Cells and Cultured Bone Marrow Stromal Cells in Graft Cell Repopulation and Tendon-Bone Healing after Allograft Anterior Cruciate Ligament Reconstruction.

Lu CC, Ho CJ, Huang HT, Lin SY, Chou SH, Chou PH, Ho ML, Tien YC
International journal of molecular sciences 2021 Mar 10;22(6)

S100 calcium-binding protein A9 from tumor-associated macrophage enhances cancer stem cell-like properties of hepatocellular carcinoma.

Wei R, Zhu WW, Yu GY, Wang X, Gao C, Zhou X, Lin ZF, Shao WQ, Wang SH, Lu M, Qin LX
International journal of cancer 2021 Mar 1;148(5):1233-1244

Polystyrene microplastics induced male reproductive toxicity in mice.

Jin H, Ma T, Sha X, Liu Z, Zhou Y, Meng X, Chen Y, Han X, Ding J
Journal of hazardous materials 2021 Jan 5;401:123430

Visfatin promotes intervertebral disc degeneration by inducing IL-6 expression through the ERK/JNK/p38 signalling pathways.

Cui H, Du X, Liu C, Chen S, Cui H, Liu H, Wang J, Zheng Z
Adipocyte 2021 Dec;10(1):201-215

Chicoric acid attenuates hyperglycemia-induced endothelial dysfunction through AMPK-dependent inhibition of oxidative/nitrative stresses.

Ma X, Zhang J, Wu Z, Wang X
Journal of receptor and signal transduction research 2021 Aug;41(4):378-392

Resveratrol affects the expression of uric acid transporter by improving inflammation.

Zhang X, Nie Q, Zhang Z, Zhao J, Zhang F, Wang C, Wang X, Song G
Molecular medicine reports 2021 Aug;24(2)

Glycyrrhizic Acid Alleviates Lipopolysaccharide (LPS)-Induced Acute Lung Injury by Regulating Angiotensin-Converting Enzyme-2 (ACE2) and Caveolin-1 Signaling Pathway.

Chen Y, Qu L, Li Y, Chen C, He W, Shen L, Zhang R
Inflammation 2021 Aug 24;

Fuzheng Huayu Recipe Prevented and Treated CCl4-Induced Mice Liver Fibrosis through Regulating Polarization and Chemotaxis of Intrahepatic Macrophages via CCL2 and CX3CL1.

Zhang M, Liu HL, Huang K, Peng Y, Tao YY, Zhao CQ, Hu XD, Liu CH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:8591892

Effects of sildenafil on inflammatory injury of the lung in sodium taurocholate-induced severe acute pancreatitis rats.

Fang D, Lin Q, Wang C, Zheng C, Li Y, Huang T, Ni F, Wu Z, Chen B, Sun L
International immunopharmacology 2020 Mar;80:106151

Chemokine CCL2 contributes to BBB disruption via the p38 MAPK signaling pathway following acute intracerebral hemorrhage.

Guo F, Xu D, Lin Y, Wang G, Wang F, Gao Q, Wei Q, Lei S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1872-1884

CCL2-CCR2 Axis Potentiates NMDA Receptor Signaling to Aggravate Neuropathic Pain Induced by Brachial Plexus Avulsion.

Xian H, Jiang Y, Zhang H, Ma SB, Zhao R, Cong R
Neuroscience 2020 Jan 15;425:29-38

Human chorionic gonadotropin promotes recruitment of regulatory T cells in endometrium by inducing chemokine CCL2.

Huang X, Cai Y, Ding M, Zheng B, Sun H, Zhou J
Journal of reproductive immunology 2020 Feb;137:102856

Endothelial cell‑derived CCL15 mediates the transmigration of fibrocytes through the CCL15‑CCR1 axis in vitro.

Pang N, Lin Z, Wang X, Xu L, Xu X, Huang R, Li X, Li X, Li J
Molecular medicine reports 2020 Dec;22(6):5339-5347

Wnt5a is involved in LOX-1 and TLR4 induced host inflammatory response in peri-implantitis.

Zhang Q, Liu J, Ma L, Bai N, Xu H
Journal of periodontal research 2020 Apr;55(2):199-208

Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells.

Zhu Y, Yu F, Tan Y, Hong Y, Meng T, Liu Y, Dai S, Qiu G, Yuan H, Hu F
Theranostics 2019;9(23):6764-6779

TLR4 gene in the regulation of periodontitis and its molecular mechanism.

Qi W, Yang X, Ye N, Li S, Han Q, Huang J, Wu B
Experimental and therapeutic medicine 2019 Sep;18(3):1961-1966

Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis.

Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, Liu K, Sun H
Pharmacological research 2019 Oct;148:104414

Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways.

Zheng C, Wu SM, Lian H, Lin YZ, Zhuang R, Thapa S, Chen QZ, Chen YF, Lin JF
Journal of cellular and molecular medicine 2019 Mar;23(3):1963-1975

Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway.

Wang R, Li D, Ouyang J, Tian X, Zhao Y, Peng X, Li S, Yu G, Yang J
Toxicology 2019 Jun 15;422:1-13

PLEK2 promotes gallbladder cancer invasion and metastasis through EGFR/CCL2 pathway.

Shen H, He M, Lin R, Zhan M, Xu S, Huang X, Xu C, Chen W, Yao Y, Mohan M, Wang J
Journal of experimental & clinical cancer research : CR 2019 Jun 10;38(1):247

Immunogenomic analysis reveals LGALS1 contributes to the immune heterogeneity and immunosuppression in glioma.

Chen Q, Han B, Meng X, Duan C, Yang C, Wu Z, Magafurov D, Zhao S, Safin S, Jiang C, Cai J
International journal of cancer 2019 Jul 15;145(2):517-530

Pigment epithelium-derived factor inhibits adipogenesis in 3T3-L1 adipocytes and protects against high-fat diet-induced obesity and metabolic disorders in mice.

Chen CC, Lee TY, Leu YL, Wang SH
Translational research : the journal of laboratory and clinical medicine 2019 Aug;210:26-42

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Fukuda D, Nishimoto S, Aini K, Tanaka A, Nishiguchi T, Kim-Kaneyama JR, Lei XF, Masuda K, Naruto T, Tanaka K, Higashikuni Y, Hirata Y, Yagi S, Kusunose K, Yamada H, Soeki T, Imoto I, Akasaka T, Shimabukuro M, Sata M
Journal of the American Heart Association 2019 Apr 2;8(7):e010860

S3I-201 ameliorates tubulointerstitial lesion of the kidneys in MRL/lpr mice.

Du Y, Zhang W, Liu S, Feng X, Gao F, Liu Q
Biochemical and biophysical research communications 2018 Sep 3;503(1):177-180

A simple multi-well stretching device to induce inflammatory responses of vascular endothelial cells.

Wang J, Fan B, Wei Y, Suo X, Ding Y
Lab on a chip 2016 Jan 21;16(2):360-7

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