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Learn66272-1-Ig
antibody from Proteintech Group
Targeting: CCL2
GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [61]
- Comments [0]
- Validations [0]
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- Product number
- 66272-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- MCP1 antibody
- Antibody type
- Monoclonal
- Description
- Mcp1 antibody (Cat. #66272-1-Ig) is a mouse monoclonal antibody that shows reactivity with mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1B9F7
- Vial size
- 20ul, 150ul
Submitted references RIPK3-Dependent Necroptosis Activates MCP-1-Mediated Inflammation in Mice after Intracerebral Hemorrhage.
The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
Breast Tumor-Derived Exosomal MicroRNA-200b-3p Promotes Specific Organ Metastasis Through Regulating CCL2 Expression in Lung Epithelial Cells.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Network Pharmacology Analysis of ZiShenWan for Diabetic Nephropathy and Experimental Verification of Its Anti-Inflammatory Mechanism.
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome.
CCL2 is a critical mechano-responsive mediator in crosstalk between osteoblasts and bone mesenchymal stromal cells.
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment.
Andrographolide attenuates synovial inflammation of osteoarthritis by interacting with tumor necrosis factor receptor 2 trafficking in a rat model.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
SHP-1 suppresses endotoxin-induced uveitis by inhibiting the TAK1/JNK pathway.
Sporoderm-Removed Ganoderma lucidum Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway.
CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis.
YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain.
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage.
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Ketogenic diet aggravates cardiac remodeling in adult spontaneously hypertensive rats.
Transcriptome Analysis Revealed Inflammation Is Involved in the Impairment of Human Umbilical Vein Endothelial Cells Induced by Post-hemorrhagic Shock Mesenteric Lymph.
Blockage of C-C Chemokine Ligand 2 Alleviated the Appendicitis-Induced Injury in Rabbit Model.
Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia.
Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE-/- mice.
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
Cortistatin protects against inflammatory airway diseases through curbing CCL2 and antagonizing NF-κB signaling pathway.
Neuronal/astrocytic expression of chemokine (C-C motif) ligand 2 is associated with monocyte/macrophage recruitment in male chronic pelvic pain.
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression.
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Glibenclamide ameliorates transplant-induced arteriosclerosis and inhibits macrophage migration and MCP-1 expression.
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Acupuncture reduces pain in rats with osteoarthritis by inhibiting MCP2/CCR2 signaling pathway.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Louqin Zhisou Decoction Inhibits Mucus Hypersecretion for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Rats by Suppressing EGFR-PI3K-AKT Signaling Pathway and Restoring Th17/Treg Balance.
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Transcriptomes in rat sciatic nerves at different stages of experimental autoimmune neuritis determined by RNA sequencing.
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Autologous nanofat transplantation accelerates foot wound healing in diabetic rats.
Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α.
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
The P2Y14 receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain.
BpV(pic) confers neuroprotection by inhibiting M1 microglial polarization and MCP-1 expression in rat traumatic brain injury.
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Effect of rosuvastatin on atherosclerotic plaque stability: An intravascular ultrasound elastography study.
Huang S, Hu W, Rao D, Wu X, Bai Q, Wang J, Chu Z, Xu Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Jan;31(1):106213
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Jan;31(1):106213
The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.
Shen Y, Li Y, Zhu Q, Wang J, Huang Y, Liang J, Wu X, Zhao Y
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
Xu T, Wang X, Ma C, Ji J, Xu W, Shao Q, Liao X, Li Y, Cheng F, Wang Q
Journal of ethnopharmacology 2022 Feb 10;284:114773
Journal of ethnopharmacology 2022 Feb 10;284:114773
Breast Tumor-Derived Exosomal MicroRNA-200b-3p Promotes Specific Organ Metastasis Through Regulating CCL2 Expression in Lung Epithelial Cells.
Gu P, Sun M, Li L, Yang Y, Jiang Z, Ge Y, Wang W, Mu W, Wang H
Frontiers in cell and developmental biology 2021;9:657158
Frontiers in cell and developmental biology 2021;9:657158
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Network Pharmacology Analysis of ZiShenWan for Diabetic Nephropathy and Experimental Verification of Its Anti-Inflammatory Mechanism.
Guo X, Wu Y, Zhang C, Wu L, Qin L, Liu T
Drug design, development and therapy 2021;15:1577-1594
Drug design, development and therapy 2021;15:1577-1594
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Huang C, Ou R, Chen X, Zhang Y, Li J, Liang Y, Zhu X, Liu L, Li M, Lin D, Qiu J, Liu G, Zhang L, Wu Y, Tang H, Liu Y, Liang L, Ding Y, Liao W
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome.
Jin L, Li Q, Li J, Pan Y, Zou J, Wu X, Wang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21907
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21907
CCL2 is a critical mechano-responsive mediator in crosstalk between osteoblasts and bone mesenchymal stromal cells.
Yao Z, Chen P, Fan L, Chen P, Zhang X, Yu B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21851
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21851
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Yang W, He H, Wang T, Su N, Zhang F, Jiang K, Zhu J, Zhang C, Niu K, Wang L, Yuan X, Liu N, Li L, Wei W, Hu J
Hepatology (Baltimore, Md.) 2021 Nov;74(5):2774-2790
Hepatology (Baltimore, Md.) 2021 Nov;74(5):2774-2790
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Li Z, Li Q, Wang L, Li C, Xu M, Duan Y, Ma L, Li T, Chen Q, Wang Y, Wang Y, Feng J, Yin X, Wang X, Han J, Lu C
Redox biology 2021 Nov;47:102156
Redox biology 2021 Nov;47:102156
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817
Food & function 2021 Mar 1;12(4):1803-1817
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
Xu D, Gao Q, Wang F, Peng Q, Wang G, Wei Q, Lei S, Zhao S, Zhang L, Guo F
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment.
Myakala K, Jones BA, Wang XX, Levi M
American journal of physiology. Renal physiology 2021 Jun 1;320(6):F1133-F1151
American journal of physiology. Renal physiology 2021 Jun 1;320(6):F1133-F1151
Andrographolide attenuates synovial inflammation of osteoarthritis by interacting with tumor necrosis factor receptor 2 trafficking in a rat model.
Wang R, Li J, Xu X, Xu J, Jiang H, Lv Z, Wu R, Sun Z, Guo W, Sun Y, Ikegawa S, Jiang Q, Shi D
Journal of orthopaedic translation 2021 Jul;29:89-99
Journal of orthopaedic translation 2021 Jul;29:89-99
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
SHP-1 suppresses endotoxin-induced uveitis by inhibiting the TAK1/JNK pathway.
Zhuang X, Ma J, Xu S, Sun Z, Zhang R, Zhang M, Xu G
Journal of cellular and molecular medicine 2021 Jan;25(1):147-160
Journal of cellular and molecular medicine 2021 Jan;25(1):147-160
Sporoderm-Removed Ganoderma lucidum Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway.
Liu G, Zeng T
Integrative cancer therapies 2021 Jan-Dec;20:15347354211062157
Integrative cancer therapies 2021 Jan-Dec;20:15347354211062157
CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis.
Huang YH, Cai K, Xu PP, Wang L, Huang CX, Fang Y, Cheng S, Sun XJ, Liu F, Huang JY, Ji MM, Zhao WL
Signal transduction and targeted therapy 2021 Jan 11;6(1):10
Signal transduction and targeted therapy 2021 Jan 11;6(1):10
YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain.
Sun M, Sun Y, Ma J, Li K
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Cheng Z, Lv D, Luo M, Wang R, Guo Y, Yang X, Huang L, Li X, Li C, Shang FF, Huang B, Shen J, Luo S, Yan J
European journal of pharmacology 2021 Aug 15;905:174186
European journal of pharmacology 2021 Aug 15;905:174186
Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage.
Balzano T, Leone P, Ivaylova G, Castro MC, Reyes L, Ramón C, Malaguarnera M, Llansola M, Felipo V
Biomedicines 2021 Aug 12;9(8)
Biomedicines 2021 Aug 12;9(8)
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
Sun N, Dou X, Tang Z, Zhang D, Ni N, Wang J, Gao H, Ju Y, Dai X, Zhao C, Gu P, Ji J, Feng C
Bioactive materials 2021 Apr;6(4):990-997
Bioactive materials 2021 Apr;6(4):990-997
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, Chi T, Zou L, Wang S, He Z
Oxidative medicine and cellular longevity 2020;2020:7950457
Oxidative medicine and cellular longevity 2020;2020:7950457
Ketogenic diet aggravates cardiac remodeling in adult spontaneously hypertensive rats.
You Y, Guo Y, Jia P, Zhuang B, Cheng Y, Deng H, Wang X, Zhang C, Luo S, Huang B
Nutrition & metabolism 2020;17:91
Nutrition & metabolism 2020;17:91
Transcriptome Analysis Revealed Inflammation Is Involved in the Impairment of Human Umbilical Vein Endothelial Cells Induced by Post-hemorrhagic Shock Mesenteric Lymph.
Wang Q, Chi ZF, Wei D, Zhao ZA, Zhang H, Zhang LM, Liu YX, Kang AL, Zhao M, Wang P, Nie LH, Niu CY, Zhao ZG
Frontiers in immunology 2020;11:1717
Frontiers in immunology 2020;11:1717
Blockage of C-C Chemokine Ligand 2 Alleviated the Appendicitis-Induced Injury in Rabbit Model.
Liu W, Zeng A, Tang H, Qiang J
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Sep;40(9):446-453
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Sep;40(9):446-453
Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia.
Xie ST, Chen AX, Song B, Fan J, Li W, Xing Z, Peng SY, Zhang QP, Dong L, Yan C, Zhang XY, Wang JJ, Zhu JN
Brain, behavior, and immunity 2020 Oct;89:400-413
Brain, behavior, and immunity 2020 Oct;89:400-413
Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE-/- mice.
Li T, Safitri M, Zhang K, Wang Y, Huang L, Zhu Y, Daniel R, Wu LJ, Qiu J, Wang G
Atherosclerosis 2020 Oct;310:64-74
Atherosclerosis 2020 Oct;310:64-74
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
Yang Y, Li L, Xu C, Wang Y, Wang Z, Chen M, Jiang Z, Pan J, Yang C, Li X, Song K, Yan J, Xie W, Wu X, Chen Z, Yuan Y, Zheng S, Yan J, Huang J, Qiu F
Gut 2020 Oct 29;
Gut 2020 Oct 29;
Cortistatin protects against inflammatory airway diseases through curbing CCL2 and antagonizing NF-κB signaling pathway.
Qiu C, Li J, Luo D, Chen X, Qu R, Liu T, Li F, Liu Y
Biochemical and biophysical research communications 2020 Oct 22;531(4):595-601
Biochemical and biophysical research communications 2020 Oct 22;531(4):595-601
Neuronal/astrocytic expression of chemokine (C-C motif) ligand 2 is associated with monocyte/macrophage recruitment in male chronic pelvic pain.
Liu Z, Murphy SF, Wong L, Schaeffer AJ, Thumbikat P
Pain 2020 Nov;161(11):2581-2591
Pain 2020 Nov;161(11):2581-2591
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Cawthon CR, Kirkland RA, Pandya S, Brinson NA, de La Serre CB
Physiology & behavior 2020 Nov 1;226:113124
Physiology & behavior 2020 Nov 1;226:113124
Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression.
Cao MX, Zhang WL, Yu XH, Wu JS, Qiao XW, Huang MC, Wang K, Wu JB, Tang YJ, Jiang J, Liang XH, Tang YL
Journal of experimental & clinical cancer research : CR 2020 Jun 3;39(1):102
Journal of experimental & clinical cancer research : CR 2020 Jun 3;39(1):102
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
He Y, Li W, Wang Y, Tian Y, Chen X, Wu Z, Lan T, Li Y, Bai M, Liu J, Cheng K, Xie P
Journal of affective disorders 2020 Jun 15;271:262-271
Journal of affective disorders 2020 Jun 15;271:262-271
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Glibenclamide ameliorates transplant-induced arteriosclerosis and inhibits macrophage migration and MCP-1 expression.
Zou Y, Zhou C, Xu H, Yu J, Ye P, Zhang H, Chen S, Zhao J, Le S, Cui J, Jiang L, Wu J, Xia J
Life sciences 2020 Jan 15;241:117141
Life sciences 2020 Jan 15;241:117141
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Xu K, Liu X, Yin D, Ren G, Zhao Y
Life sciences 2020 Feb 15;243:117270
Life sciences 2020 Feb 15;243:117270
Acupuncture reduces pain in rats with osteoarthritis by inhibiting MCP2/CCR2 signaling pathway.
Li B, Jing L, Jia L, Qian T, Jianyi C, Zhongsheng H, Xiaohong Z, Guowei C
Experimental biology and medicine (Maywood, N.J.) 2020 Dec;245(18):1722-1731
Experimental biology and medicine (Maywood, N.J.) 2020 Dec;245(18):1722-1731
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D
Life sciences 2020 Aug 15;255:117719
Life sciences 2020 Aug 15;255:117719
Louqin Zhisou Decoction Inhibits Mucus Hypersecretion for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Rats by Suppressing EGFR-PI3K-AKT Signaling Pathway and Restoring Th17/Treg Balance.
Feng F, Du J, Meng Y, Guo F, Feng C
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6471815
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6471815
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
Yu X, Li Z, Zhang Y, Xu M, Che Y, Tian X, Wang R, Zou K, Zou L
OncoTargets and therapy 2019;12:4203-4211
OncoTargets and therapy 2019;12:4203-4211
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Zhou Z, Dong Y, Zhou H, Liu J, Zhao W
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Transcriptomes in rat sciatic nerves at different stages of experimental autoimmune neuritis determined by RNA sequencing.
Xue Y, Yin P, Li G, Zhong D
Clinical and experimental immunology 2019 Nov;198(2):184-197
Clinical and experimental immunology 2019 Nov;198(2):184-197
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Shi L, Wang J, Ding N, Zhang Y, Zhu Y, Dong S, Wang X, Peng C, Zhou C, Zhou L, Li X, Shi H, Wu W, Long X, Wu C, Liao W
Nature communications 2019 Nov 28;10(1):5421
Nature communications 2019 Nov 28;10(1):5421
Autologous nanofat transplantation accelerates foot wound healing in diabetic rats.
Chen L, Wang ZC, Ma JJ, Sun WJ, Wang SW, Gu ZC, Yang X
Regenerative medicine 2019 Mar;14(3):231-241
Regenerative medicine 2019 Mar;14(3):231-241
Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α.
Zhang L, Li HX, Pan WS, Ullah Khan F, Qian C, Qi-Li FR, Xu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:99-108
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:99-108
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Yuan G, Xu L, Cai T, Hua B, Sun N, Yan Z, Lu C, Qian R
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Han J, Guo D, Sun XY, Wang JM, Ouyang JM, Gui BS
Scientific reports 2019 Jul 8;9(1):9871
Scientific reports 2019 Jul 8;9(1):9871
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
Zhu X, Du J, Yu J, Guo R, Feng Y, Qiao L, Xu Z, Yang F, Zhong G, Liu F, Cheng F, Chu M, Lin J
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
The P2Y14 receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain.
Lin J, Zhang YY, Liu F, Fang XY, Liu MK, Huang CL, Wang H, Liao DQ, Zhou C, Shen JF
Neurochemistry international 2019 Dec;131:104567
Neurochemistry international 2019 Dec;131:104567
BpV(pic) confers neuroprotection by inhibiting M1 microglial polarization and MCP-1 expression in rat traumatic brain injury.
Liu R, Liao XY, Tang JC, Pan MX, Chen SF, Lu PX, Lu LJ, Zhang ZF, Zou YY, Bu LH, Qin XP, Wan Q
Molecular immunology 2019 Aug;112:30-39
Molecular immunology 2019 Aug;112:30-39
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, Peng W, Han D, Zhou X, Wu J, He H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.
Li X, Jia L, Chen X, Dong Y, Ren X, Dong Y, Chen Y, Xie L, Liu M, Shiota C, Gittes GK, Rui L, Chen Z
Theranostics 2018;8(21):5960-5971
Theranostics 2018;8(21):5960-5971
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Sun HJ, Chen D, Wang PY, Wan MY, Zhang CX, Zhang ZX, Lin W, Zhang F
Oxidative medicine and cellular longevity 2017;2017:6905217
Oxidative medicine and cellular longevity 2017;2017:6905217
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Liu Q, Du Y, Li K, Zhang W, Feng X, Hao J, Li H, Liu S
Mediators of inflammation 2017;2017:3038514
Mediators of inflammation 2017;2017:3038514
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Wang J, Fu X, Zhang D, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Wang M, Liu X, Chen X, Zang W, Yang Q, Wang J
Neuroscience 2017 Nov 19;364:202-211
Neuroscience 2017 Nov 19;364:202-211
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Gu R, Lei B, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Xu X, Fan Z, Qi X, Shao Y, Wu Y
International immunopharmacology 2016 Sep;38:120-31
International immunopharmacology 2016 Sep;38:120-31
Effect of rosuvastatin on atherosclerotic plaque stability: An intravascular ultrasound elastography study.
Li Z, Wang L, Hu X, Zhang P, Chen Y, Liu X, Xu M, Zhang Y, Zhang M
Atherosclerosis 2016 May;248:27-35
Atherosclerosis 2016 May;248:27-35
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