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Learn66272-1-Ig
antibody from Proteintech Group
Targeting: CCL2
GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [125]
- Comments [0]
- Validations [0]
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- Product number
- 66272-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- MCP1 antibody
- Antibody type
- Monoclonal
- Description
- Mcp1 antibody (Cat. #66272-1-Ig) is a mouse monoclonal antibody that shows reactivity with mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1B9F7
- Vial size
- 20ul, 150ul
Submitted references Macrophages promote the transition from myocardial ischemia reperfusion injury to cardiac fibrosis in mice through GMCSF/CCL2/CCR2 and phenotype switching.
Single-Cell RNA-Seq Reveals Coronary Heterogeneity and Identifies CD133(+)TRPV4(high) Endothelial Subpopulation in Regulating Flow-Induced Vascular Tone in Mice.
Modified Guo-Min decoction ameliorates PM2.5-induced lung injury by inhibition of PI3K-AKT and MAPK signaling pathways.
Bushen Antai recipe alleviates embryo absorption by enhancing immune tolerance and angiogenesis at the maternal-fetal interface via mobilizing MDSCs in abortion-prone mice.
Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone mice.
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction.
Tumor-derived Cav-1 promotes pre-metastatic niche formation and lung metastasis in breast cancer.
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2-ERK depending on downregulation of proteasome-related genes.
Engineered Knockout of TRPA1 Inhibits Laser-Induced Choroidal Neovascularization Along With Associated TGFβ1 Expression and Neutrophil Infiltration.
Microglial voltage-dependent anion channel 1 signaling modulates sleep deprivation-induced transition to chronic postsurgical pain.
Hypoxia-induced CCL2/CCR2 axis in adipose-derived stem cells (ADSCs) promotes angiogenesis by human dermal microvascular endothelial cells (HDMECs) in flap tissues.
A druggable copper-signalling pathway that drives inflammation.
Comprehensive analysis of autophagy-related gene expression profiles identified five gene biomarkers associated with immune infiltration and advanced plaques in carotid atherosclerosis.
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
CC Chemokine 2 Promotes Ovarian Cancer Progression through the MEK/ERK/MAP3K19 Signaling Pathway.
Targeted Deletion of Rictor in BMSCs Reduces the Biological Activity of K7M2 Cells and Mitigates OS-Induced Bone Destruction.
QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation.
Prox1 Suppresses the Proliferation of Breast Cancer Cells via Direct Inhibition of c-Myc Gene Expression.
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
M2 macrophages with inflammation tropism facilitate cementoblast mineralization.
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization.
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling.
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Serum levels of C-C motif chemokine ligand 2 and interleukin-8 as possible biomarkers in patients with toxic epidermal necrolysis accompanied by acute respiratory distress syndrome.
Effect and Mechanism of Qingfei Paidu Decoction in the Management of Pulmonary Fibrosis and COVID-19.
Effects of Crocin on CCL2/CCR2 Inflammatory Pathway in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats.
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Ginsenoside Rd Promotes Cardiac Repair After Myocardial Infarction by Modulating Monocytes/Macrophages Subsets Conversion.
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Esaxerenone inhibits the macrophage-to-myofibroblast transition through mineralocorticoid receptor/TGF-β1 pathway in mice induced with aldosterone.
Extracellular Vesicles From Hyperammonemic Rats Induce Neuroinflammation in Cerebellum of Normal Rats: Role of Increased TNFα Content.
Aberrant peribiliary gland niche exacerbates fibrosis in primary sclerosing cholangitis and a potential therapeutic strategy.
P2Y(14) receptor in trigeminal ganglion contributes to neuropathic pain in mice.
Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis.
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects.
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Dissecting Heterogeneity Reveals a Unique BAMBI(high) MFGE8(high) Subpopulation of Human UC-MSCs.
Rifaximin Improves Spatial Learning and Memory Impairment in Rats with Liver Damage-Associated Neuroinflammation.
Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation.
Pathogenic Tconvs promote inflammatory macrophage polarization through GM-CSF and exacerbate abdominal aortic aneurysm formation.
Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy.
Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling.
Activating cGAS-STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis.
Targeting Ferroptosis Attenuates Interstitial Inflammation and Kidney Fibrosis.
RIPK3-Dependent Necroptosis Activates MCP-1-Mediated Inflammation in Mice after Intracerebral Hemorrhage.
The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
Periostin contributes to the adventitial remodeling of atherosclerosis by activating adventitial fibroblasts.
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
Verteporfin-mediated on/off photoswitching functions synergistically to treat choroidal vascular diseases.
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Enterobacter cloacae: a villain in CaOx stone disease?
TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis.
Breast Tumor-Derived Exosomal MicroRNA-200b-3p Promotes Specific Organ Metastasis Through Regulating CCL2 Expression in Lung Epithelial Cells.
Cilengitide Inhibits Neovascularization in a Rabbit Abdominal Aortic Plaque Model by Impairing the VEGF Signaling.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Network Pharmacology Analysis of ZiShenWan for Diabetic Nephropathy and Experimental Verification of Its Anti-Inflammatory Mechanism.
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome.
CCL2 is a critical mechano-responsive mediator in crosstalk between osteoblasts and bone mesenchymal stromal cells.
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment.
Andrographolide attenuates synovial inflammation of osteoarthritis by interacting with tumor necrosis factor receptor 2 trafficking in a rat model.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
SHP-1 suppresses endotoxin-induced uveitis by inhibiting the TAK1/JNK pathway.
Sporoderm-Removed Ganoderma lucidum Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway.
CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis.
Disruption of P2X4 purinoceptor and suppression of the inflammation associated with cerebral aneurysm formation.
YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain.
Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response.
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage.
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Ketogenic diet aggravates cardiac remodeling in adult spontaneously hypertensive rats.
Transcriptome Analysis Revealed Inflammation Is Involved in the Impairment of Human Umbilical Vein Endothelial Cells Induced by Post-hemorrhagic Shock Mesenteric Lymph.
Blockage of C-C Chemokine Ligand 2 Alleviated the Appendicitis-Induced Injury in Rabbit Model.
Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia.
Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE(-/-) mice.
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
Cortistatin protects against inflammatory airway diseases through curbing CCL2 and antagonizing NF-κB signaling pathway.
Neuronal/astrocytic expression of chemokine (C-C motif) ligand 2 is associated with monocyte/macrophage recruitment in male chronic pelvic pain.
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression.
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Glibenclamide ameliorates transplant-induced arteriosclerosis and inhibits macrophage migration and MCP-1 expression.
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Acupuncture reduces pain in rats with osteoarthritis by inhibiting MCP2/CCR2 signaling pathway.
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Louqin Zhisou Decoction Inhibits Mucus Hypersecretion for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Rats by Suppressing EGFR-PI3K-AKT Signaling Pathway and Restoring Th17/Treg Balance.
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Transcriptomes in rat sciatic nerves at different stages of experimental autoimmune neuritis determined by RNA sequencing.
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Autologous nanofat transplantation accelerates foot wound healing in diabetic rats.
Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α.
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
The P2Y(14) receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain.
BpV(pic) confers neuroprotection by inhibiting M1 microglial polarization and MCP-1 expression in rat traumatic brain injury.
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Effect of rosuvastatin on atherosclerotic plaque stability: An intravascular ultrasound elastography study.
Shen SC, Xu J, Cheng C, Xiang XJ, Hong BY, Zhang M, Gong C, Ma LK
Acta pharmacologica Sinica 2024 May;45(5):959-974
Acta pharmacologica Sinica 2024 May;45(5):959-974
Single-Cell RNA-Seq Reveals Coronary Heterogeneity and Identifies CD133(+)TRPV4(high) Endothelial Subpopulation in Regulating Flow-Induced Vascular Tone in Mice.
Mao A, Zhang K, Kan H, Gao M, Wang Z, Zhou T, Shao J, He D
Arteriosclerosis, thrombosis, and vascular biology 2024 Mar;44(3):653-665
Arteriosclerosis, thrombosis, and vascular biology 2024 Mar;44(3):653-665
Modified Guo-Min decoction ameliorates PM2.5-induced lung injury by inhibition of PI3K-AKT and MAPK signaling pathways.
Wang H, Wang G, Meng Y, Liu Y, Yao X, Feng C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155211
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155211
Bushen Antai recipe alleviates embryo absorption by enhancing immune tolerance and angiogenesis at the maternal-fetal interface via mobilizing MDSCs in abortion-prone mice.
Liu Z, Geng Y, Huang Y, Hu R, Li F, Ding J, Ma W, Dong H, Song K, Xu X, Wu X, Song Y, Zhang M
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155164
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jan;123:155164
Bushen Antai recipe ameliorates immune microenvironment and maternal-fetal vascularization in STAT3-deficient abortion-prone mice.
Liu Z, Song Y, Hu R, Geng Y, Huang Y, Li F, Ma W, Dong H, Song K, Ding J, Xu X, Wu X, Zhang M, Zhong Z
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116889
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116889
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation.
Arenas YM, Izquierdo-Altarejos P, Martinez-García M, Giménez-Garzó C, Mincheva G, Doverskog M, Jones DEJ, Balzano T, Llansola M, Felipo V
Liver international : official journal of the International Association for the Study of the Liver 2024 Feb;44(2):433-445
Liver international : official journal of the International Association for the Study of the Liver 2024 Feb;44(2):433-445
Downregulation of CPSF6 leads to global mRNA 3' UTR shortening and enhanced antiviral immune responses.
Ge Y, Huang J, Chen R, Fu Y, Ling T, Ou X, Rong X, Cheng Y, Lin Y, Zhou F, Lu C, Yuan S, Xu A
PLoS pathogens 2024 Feb;20(2):e1012061
PLoS pathogens 2024 Feb;20(2):e1012061
Direct targeting of sEH with alisol B alleviated the apoptosis, inflammation, and oxidative stress in cisplatin-induced acute kidney injury.
Zhang J, Luan ZL, Huo XK, Zhang M, Morisseau C, Sun CP, Hammock BD, Ma XC
International journal of biological sciences 2023;19(1):294-310
International journal of biological sciences 2023;19(1):294-310
Shensong Yangxin Capsule Reduces the Susceptibility of Arrhythmia in db/db Mice via Inhibiting the Inflammatory Response Induced by Endothelium Dysfunction.
Zhang J, Li H, Wang D, Gu J, Hou Y, Wu Y
Drug design, development and therapy 2023;17:313-330
Drug design, development and therapy 2023;17:313-330
Tumor-derived Cav-1 promotes pre-metastatic niche formation and lung metastasis in breast cancer.
Wang Y, Li Y, Zhong J, Li M, Zhou Y, Lin Q, Zong S, Luo W, Wang J, Wang K, Wang J, Xiong L
Theranostics 2023;13(5):1684-1697
Theranostics 2023;13(5):1684-1697
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hong SY, Yang YY, Wang SG, Qin BL
Chemico-biological interactions 2023 Sep 1;382:110636
Chemico-biological interactions 2023 Sep 1;382:110636
Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2-ERK depending on downregulation of proteasome-related genes.
Li X, Liu C, Zhang Z, Li X, Yao Z, Dong Y, Wang X, Chen Z
The Journal of biological chemistry 2023 Nov;299(11):105301
The Journal of biological chemistry 2023 Nov;299(11):105301
Engineered Knockout of TRPA1 Inhibits Laser-Induced Choroidal Neovascularization Along With Associated TGFβ1 Expression and Neutrophil Infiltration.
Usui Y, Iwanishi H, Sumioka T, Ichikawa K, Miyajima M, Usui-Kusumoto K, Reinach PS, Okada Y, Saika S
Laboratory investigation; a journal of technical methods and pathology 2023 Nov;103(11):100256
Laboratory investigation; a journal of technical methods and pathology 2023 Nov;103(11):100256
Microglial voltage-dependent anion channel 1 signaling modulates sleep deprivation-induced transition to chronic postsurgical pain.
Wei SN, Zhang H, Lu Y, Yu HJ, Ma T, Wang SN, Yang K, Tian ML, Huang AH, Wang W, Li FS, Li YW
Sleep 2023 Nov 8;46(11)
Sleep 2023 Nov 8;46(11)
Hypoxia-induced CCL2/CCR2 axis in adipose-derived stem cells (ADSCs) promotes angiogenesis by human dermal microvascular endothelial cells (HDMECs) in flap tissues.
Fang B, Wang X, Sun Y, Xiong X, Meng X, Li W, Yi Z
Journal of physiology and biochemistry 2023 May;79(2):327-339
Journal of physiology and biochemistry 2023 May;79(2):327-339
A druggable copper-signalling pathway that drives inflammation.
Solier S, Müller S, Cañeque T, Versini A, Mansart A, Sindikubwabo F, Baron L, Emam L, Gestraud P, Pantoș GD, Gandon V, Gaillet C, Wu TD, Dingli F, Loew D, Baulande S, Durand S, Sencio V, Robil C, Trottein F, Péricat D, Näser E, Cougoule C, Meunier E, Bègue AL, Salmon H, Manel N, Puisieux A, Watson S, Dawson MA, Servant N, Kroemer G, Annane D, Rodriguez R
Nature 2023 May;617(7960):386-394
Nature 2023 May;617(7960):386-394
Comprehensive analysis of autophagy-related gene expression profiles identified five gene biomarkers associated with immune infiltration and advanced plaques in carotid atherosclerosis.
Ma C, Lu T, He Y, Guo D, Duan L, Jia R, Cai D, Gao T, Chen Z, Xue B, Li T, He Y
Orphanet journal of rare diseases 2023 Mar 23;18(1):66
Orphanet journal of rare diseases 2023 Mar 23;18(1):66
IGFBP2 derived from PO-MSCs promote epithelial barrier destruction by activating FAK signaling in nasal polyps.
You B, Zhang T, Zhang W, Pei Y, Huang D, Lei Y, Zhang S, Qiu C, Zhang J, Gu Z, Cheng L, Chen J
iScience 2023 Mar 17;26(3):106151
iScience 2023 Mar 17;26(3):106151
CC Chemokine 2 Promotes Ovarian Cancer Progression through the MEK/ERK/MAP3K19 Signaling Pathway.
Liu W, Wang L, Zhang J, Cheng K, Zheng W, Ma Z
International journal of molecular sciences 2023 Jun 26;24(13)
International journal of molecular sciences 2023 Jun 26;24(13)
Targeted Deletion of Rictor in BMSCs Reduces the Biological Activity of K7M2 Cells and Mitigates OS-Induced Bone Destruction.
Lu J, Dai D, Zhang J, Wang R, Miao D, Sun W
Stem cells (Dayton, Ohio) 2023 Jun 15;41(6):672-683
Stem cells (Dayton, Ohio) 2023 Jun 15;41(6):672-683
QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation.
Xu SY, Jia JQ, Sun M, Bao XY, Xia SN, Shu S, Liu PY, Ji SL, Ye L, Cao X, Xu Y
iScience 2023 Jul 21;26(7):107268
iScience 2023 Jul 21;26(7):107268
Prox1 Suppresses the Proliferation of Breast Cancer Cells via Direct Inhibition of c-Myc Gene Expression.
Michail A, Gkikas D, Stellas D, Kaltezioti V, Politis PK
Cells 2023 Jul 17;12(14)
Cells 2023 Jul 17;12(14)
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Li J, Sun X, Yang N, Ni J, Xie H, Guo H, Wang X, Zhou L, Liu J, Chen S, Wang X, Zhang Y, Yu C, Zhang W, Lu L
Kidney international 2023 Jan;103(1):115-133
Kidney international 2023 Jan;103(1):115-133
M2 macrophages with inflammation tropism facilitate cementoblast mineralization.
Huang X, Wang X, Ma L, Wang H, Peng Y, Liu H, Xiao J, Cao Z
Journal of periodontology 2023 Feb;94(2):290-300
Journal of periodontology 2023 Feb;94(2):290-300
Castor1 overexpression regulates microglia M1/M2 polarization via inhibiting mTOR pathway.
Hu H, Lu X, Huang L, He Y, Liu X, Wang Y, Duan C
Metabolic brain disease 2023 Feb;38(2):699-708
Metabolic brain disease 2023 Feb;38(2):699-708
Ferroptotic stress facilitates smooth muscle cell dedifferentiation in arterial remodelling by disrupting mitochondrial homeostasis.
Ji QX, Zeng FY, Zhou J, Wu WB, Wang XJ, Zhang Z, Zhang GY, Tong J, Sun DY, Zhang JB, Cao WX, Shen FM, Lu JJ, Li DJ, Wang P
Cell death and differentiation 2023 Feb;30(2):457-474
Cell death and differentiation 2023 Feb;30(2):457-474
Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction.
Tan E, Gao Z, Wang Q, Han B, Shi H, Wang L, Zhu G, Hou Y
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
Basic & clinical pharmacology & toxicology 2023 Dec;133(6):757-769
WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization.
Bai Y, Jiao X, Hu J, Xue W, Zhou Z, Wang W
Biochimica et biophysica acta. Molecular basis of disease 2023 Aug;1869(6):166708
Biochimica et biophysica acta. Molecular basis of disease 2023 Aug;1869(6):166708
Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia.
Xu X, Zhang DD, Kong P, Gao YK, Huang XF, Song Y, Zhang WD, Guo RJ, Li CL, Chen BW, Sun Y, Zhao YB, Jia FY, Wang X, Zhang F, Han M
Cell reports 2023 Aug 29;42(8):112869
Cell reports 2023 Aug 29;42(8):112869
Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling.
Huang X, Chen X, Li Q, Ni BH, Wang W
Toxicon : official journal of the International Society on Toxinology 2023 Aug 15;232:107202
Toxicon : official journal of the International Society on Toxinology 2023 Aug 15;232:107202
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y
Journal of translational medicine 2023 Aug 14;21(1):544
Journal of translational medicine 2023 Aug 14;21(1):544
Serum levels of C-C motif chemokine ligand 2 and interleukin-8 as possible biomarkers in patients with toxic epidermal necrolysis accompanied by acute respiratory distress syndrome.
Watanabe T, Watanabe Y, Ikeda N, Aihara M, Yamaguchi Y
The Journal of dermatology 2023 Apr;50(4):500-510
The Journal of dermatology 2023 Apr;50(4):500-510
Effect and Mechanism of Qingfei Paidu Decoction in the Management of Pulmonary Fibrosis and COVID-19.
Wu Y, Xu L, Cao G, Min L, Dong T
The American journal of Chinese medicine 2022;50(1):33-51
The American journal of Chinese medicine 2022;50(1):33-51
Effects of Crocin on CCL2/CCR2 Inflammatory Pathway in Monocrotaline-Induced Pulmonary Arterial Hypertension Rats.
Sheng Y, Gong X, Zhao J, Liu Y, Yuan Y
The American journal of Chinese medicine 2022;50(1):241-259
The American journal of Chinese medicine 2022;50(1):241-259
Exosomes Derived from Baicalin-Pretreated Mesenchymal Stem Cells Alleviate Hepatocyte Ferroptosis after Acute Liver Injury via the Keap1-NRF2 Pathway.
Zhao S, Huang M, Yan L, Zhang H, Shi C, Liu J, Zhao S, Liu H, Wang B
Oxidative medicine and cellular longevity 2022;2022:8287227
Oxidative medicine and cellular longevity 2022;2022:8287227
Ginsenoside Rd Promotes Cardiac Repair After Myocardial Infarction by Modulating Monocytes/Macrophages Subsets Conversion.
Zhao T, Wang X, Liu Q, Yang T, Qu H, Zhou H
Drug design, development and therapy 2022;16:2767-2782
Drug design, development and therapy 2022;16:2767-2782
NF-κB and AP-1 are required for the lipopolysaccharide-induced expression of MCP-1, CXCL1, and Cx43 in cultured rat dorsal spinal cord astrocytes.
Lu Y, Li B, Xu A, Liang X, Xu T, Jin H, Xie Y, Wang R, Liu X, Gao X, Han Y, Zeng J
Frontiers in molecular neuroscience 2022;15:859558
Frontiers in molecular neuroscience 2022;15:859558
Esaxerenone inhibits the macrophage-to-myofibroblast transition through mineralocorticoid receptor/TGF-β1 pathway in mice induced with aldosterone.
Qiang P, Hao J, Yang F, Han Y, Chang Y, Xian Y, Xiong Y, Gao X, Liang L, Shimosawa T, Xu Q
Frontiers in immunology 2022;13:948658
Frontiers in immunology 2022;13:948658
Extracellular Vesicles From Hyperammonemic Rats Induce Neuroinflammation in Cerebellum of Normal Rats: Role of Increased TNFα Content.
Izquierdo-Altarejos P, Martínez-García M, Felipo V
Frontiers in immunology 2022;13:921947
Frontiers in immunology 2022;13:921947
Aberrant peribiliary gland niche exacerbates fibrosis in primary sclerosing cholangitis and a potential therapeutic strategy.
Wu S, Cao Y, Lu H, Qi X, Sun J, Ye Y, Gong L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113512
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113512
P2Y(14) receptor in trigeminal ganglion contributes to neuropathic pain in mice.
Lin J, Fang X, Liu F, Zhang Y, Li Y, Fang Z, Tang Q, Li C, Zhou C, Shen J
European journal of pharmacology 2022 Sep 15;931:175211
European journal of pharmacology 2022 Sep 15;931:175211
Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis.
Wang Y, Gao H, Huang X, Chen Z, Kang P, Zhou Y, Qin D, Zhang W, Liu J
Carbohydrate polymers 2022 Sep 15;292:119632
Carbohydrate polymers 2022 Sep 15;292:119632
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects.
Ye C, Geng Z, Zhang LL, Zheng F, Zhou YB, Zhu GQ, Xiong XQ
Acta pharmacologica Sinica 2022 Oct;43(10):2573-2584
Acta pharmacologica Sinica 2022 Oct;43(10):2573-2584
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Su H, Mei Y, Luo S, Wu H, He Y, Shiraishi Y, Hu P, Cohen RA, Tong X
British journal of pharmacology 2022 Oct;179(20):4778-4791
British journal of pharmacology 2022 Oct;179(20):4778-4791
The Clostridium Metabolite P-Cresol Sulfate Relieves Inflammation of Primary Biliary Cholangitis by Regulating Kupffer Cells.
Fu HY, Xu JM, Ai X, Dang FT, Tan X, Yu HY, Feng J, Yang WX, Ma HT, Tu RF, Gupta AK, Manandhar LK, Bao WM, Tang YM
Cells 2022 Nov 26;11(23)
Cells 2022 Nov 26;11(23)
Dissecting Heterogeneity Reveals a Unique BAMBI(high) MFGE8(high) Subpopulation of Human UC-MSCs.
Chen H, Wen X, Liu S, Sun T, Song H, Wang F, Xu J, Zhang Y, Zhao Y, Yu J, Sun L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov 14;10(1):e2202510
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Nov 14;10(1):e2202510
Rifaximin Improves Spatial Learning and Memory Impairment in Rats with Liver Damage-Associated Neuroinflammation.
Leone P, Mincheva G, Balzano T, Malaguarnera M, Felipo V, Llansola M
Biomedicines 2022 May 28;10(6)
Biomedicines 2022 May 28;10(6)
Antibiotic pretreatment attenuates liver ischemia-reperfusion injury by Farnesoid X receptor activation.
Liu H, Wang J, Ding Y, Shi X, Ren H
Cell death & disease 2022 May 21;13(5):484
Cell death & disease 2022 May 21;13(5):484
Pathogenic Tconvs promote inflammatory macrophage polarization through GM-CSF and exacerbate abdominal aortic aneurysm formation.
Li D, Li J, Liu H, Zhai L, Hu W, Xia N, Tang T, Jiao J, Lv B, Nie S, Hu D, Liao Y, Yang X, Shi GP, Cheng X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22172
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Mar;36(3):e22172
Remodeling of dermal adipose tissue alleviates cutaneous toxicity induced by anti-EGFR therapy.
Chen L, You Q, Liu M, Li S, Wu Z, Hu J, Ma Y, Xia L, Zhou Y, Xu N, Zhang S
eLife 2022 Mar 24;11
eLife 2022 Mar 24;11
Rutin Inhibits Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation by Inducing Autophagy and Modulating PI3K/ATK Signaling.
Li B, Ji Y, Yi C, Wang X, Liu C, Wang C, Lu X, Xu X, Wang X
Molecules (Basel, Switzerland) 2022 Jun 29;27(13)
Molecules (Basel, Switzerland) 2022 Jun 29;27(13)
Activating cGAS-STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis.
Ding R, Li H, Liu Y, Ou W, Zhang X, Chai H, Huang X, Yang W, Wang Q
Journal of neuroinflammation 2022 Jun 10;19(1):137
Journal of neuroinflammation 2022 Jun 10;19(1):137
Targeting Ferroptosis Attenuates Interstitial Inflammation and Kidney Fibrosis.
Zhou L, Xue X, Hou Q, Dai C
Kidney diseases (Basel, Switzerland) 2022 Jan;8(1):57-71
Kidney diseases (Basel, Switzerland) 2022 Jan;8(1):57-71
RIPK3-Dependent Necroptosis Activates MCP-1-Mediated Inflammation in Mice after Intracerebral Hemorrhage.
Huang S, Hu W, Rao D, Wu X, Bai Q, Wang J, Chu Z, Xu Y
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Jan;31(1):106213
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2022 Jan;31(1):106213
The immunomodulatory effect of microglia on ECM neuroinflammation via the PD-1/PD-L1 pathway.
Shen Y, Li Y, Zhu Q, Wang J, Huang Y, Liang J, Wu X, Zhao Y
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
CNS neuroscience & therapeutics 2022 Jan;28(1):46-63
Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and bioinformatics analysis.
Xu T, Wang X, Ma C, Ji J, Xu W, Shao Q, Liao X, Li Y, Cheng F, Wang Q
Journal of ethnopharmacology 2022 Feb 10;284:114773
Journal of ethnopharmacology 2022 Feb 10;284:114773
LncRNA Tug1 maintains blood-testis barrier integrity by modulating Ccl2 expression in high-fat diet mice.
Wang S, Qian Z, Ge X, Li C, Xue M, Liang K, Ma R, Ouyang L, Zheng L, Jing J, Cao S, Zhang Y, Yang Y, Chen Y, Ma J, Yao B
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
Cellular and molecular life sciences : CMLS 2022 Feb 1;79(2):114
Periostin contributes to the adventitial remodeling of atherosclerosis by activating adventitial fibroblasts.
Wang Z, Li G, Li M, Hu L, Hao Z, Li Q, Sun C
Atherosclerosis plus 2022 Dec;50:57-64
Atherosclerosis plus 2022 Dec;50:57-64
Eplerenone inhibits the macrophage-to-myofibroblast transition in rats with UUO-induced type 4 cardiorenal syndrome through the MR/CTGF pathway.
Han Y, Xian Y, Gao X, Qiang P, Hao J, Yang F, Shimosawa T, Chang Y, Xu Q
International immunopharmacology 2022 Dec;113(Pt A):109396
International immunopharmacology 2022 Dec;113(Pt A):109396
Macrophages regulate vascular smooth muscle cell function during atherosclerosis progression through IL-1β/STAT3 signaling.
Xue Y, Luo M, Hu X, Li X, Shen J, Zhu W, Huang L, Hu Y, Guo Y, Liu L, Wang L, Luo S
Communications biology 2022 Dec 1;5(1):1316
Communications biology 2022 Dec 1;5(1):1316
Verteporfin-mediated on/off photoswitching functions synergistically to treat choroidal vascular diseases.
Ju Y, Dai X, Tang Z, Ming Z, Ni N, Zhu D, Zhang J, Ma B, Wang J, Huang R, Zhao S, Pang Y, Gu P
Bioactive materials 2022 Aug;14:402-415
Bioactive materials 2022 Aug;14:402-415
Deficiency of WTAP in hepatocytes induces lipoatrophy and non-alcoholic steatohepatitis (NASH).
Li X, Ding K, Li X, Yuan B, Wang Y, Yao Z, Wang S, Huang H, Xu B, Xie L, Deng T, Chen XW, Chen Z
Nature communications 2022 Aug 4;13(1):4549
Nature communications 2022 Aug 4;13(1):4549
Enterobacter cloacae: a villain in CaOx stone disease?
Yang Y, Hong S, Xu J, Li C, Wang S, Xun Y
Urolithiasis 2022 Apr;50(2):177-188
Urolithiasis 2022 Apr;50(2):177-188
TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis.
Zhang Y, Ying F, Tian X, Lei Z, Li X, Lo CY, Li J, Jiang L, Yao X
Cells 2022 Apr 22;11(9)
Cells 2022 Apr 22;11(9)
Breast Tumor-Derived Exosomal MicroRNA-200b-3p Promotes Specific Organ Metastasis Through Regulating CCL2 Expression in Lung Epithelial Cells.
Gu P, Sun M, Li L, Yang Y, Jiang Z, Ge Y, Wang W, Mu W, Wang H
Frontiers in cell and developmental biology 2021;9:657158
Frontiers in cell and developmental biology 2021;9:657158
Cilengitide Inhibits Neovascularization in a Rabbit Abdominal Aortic Plaque Model by Impairing the VEGF Signaling.
Zhu F, Yuan S, Li J, Mou Y, Hu Z, Wang X, Sun X, Ding J, Zheng Z
BioMed research international 2021;2021:5954757
BioMed research international 2021;2021:5954757
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Network Pharmacology Analysis of ZiShenWan for Diabetic Nephropathy and Experimental Verification of Its Anti-Inflammatory Mechanism.
Guo X, Wu Y, Zhang C, Wu L, Qin L, Liu T
Drug design, development and therapy 2021;15:1577-1594
Drug design, development and therapy 2021;15:1577-1594
Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC.
Huang C, Ou R, Chen X, Zhang Y, Li J, Liang Y, Zhu X, Liu L, Li M, Lin D, Qiu J, Liu G, Zhang L, Wu Y, Tang H, Liu Y, Liang L, Ding Y, Liao W
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Journal of experimental & clinical cancer research : CR 2021 Sep 28;40(1):304
Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome.
Jin L, Li Q, Li J, Pan Y, Zou J, Wu X, Wang Z
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21907
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21907
CCL2 is a critical mechano-responsive mediator in crosstalk between osteoblasts and bone mesenchymal stromal cells.
Yao Z, Chen P, Fan L, Chen P, Zhang X, Yu B
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21851
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Oct;35(10):e21851
Single-Cell Transcriptomic Analysis Reveals a Hepatic Stellate Cell-Activation Roadmap and Myofibroblast Origin During Liver Fibrosis in Mice.
Yang W, He H, Wang T, Su N, Zhang F, Jiang K, Zhu J, Zhang C, Niu K, Wang L, Yuan X, Liu N, Li L, Wei W, Hu J
Hepatology (Baltimore, Md.) 2021 Nov;74(5):2774-2790
Hepatology (Baltimore, Md.) 2021 Nov;74(5):2774-2790
Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis.
Li Z, Li Q, Wang L, Li C, Xu M, Duan Y, Ma L, Li T, Chen Q, Wang Y, Wang Y, Feng J, Yin X, Wang X, Han J, Lu C
Redox biology 2021 Nov;47:102156
Redox biology 2021 Nov;47:102156
Differential effects of EPA and DHA on DSS-induced colitis in mice and possible mechanisms involved.
Zhang Z, Xue Z, Yang H, Zhao F, Liu C, Chen J, Lu S, Zou Z, Zhou Y, Zhang X
Food & function 2021 Mar 1;12(4):1803-1817
Food & function 2021 Mar 1;12(4):1803-1817
Sphingosine-1-phosphate receptor 3 is implicated in BBB injury via the CCL2-CCR2 axis following acute intracerebral hemorrhage.
Xu D, Gao Q, Wang F, Peng Q, Wang G, Wei Q, Lei S, Zhao S, Zhang L, Guo F
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
CNS neuroscience & therapeutics 2021 Jun;27(6):674-686
Sacubitril/valsartan treatment has differential effects in modulating diabetic kidney disease in db/db mice and KKAy mice compared with valsartan treatment.
Myakala K, Jones BA, Wang XX, Levi M
American journal of physiology. Renal physiology 2021 Jun 1;320(6):F1133-F1151
American journal of physiology. Renal physiology 2021 Jun 1;320(6):F1133-F1151
Andrographolide attenuates synovial inflammation of osteoarthritis by interacting with tumor necrosis factor receptor 2 trafficking in a rat model.
Wang R, Li J, Xu X, Xu J, Jiang H, Lv Z, Wu R, Sun Z, Guo W, Sun Y, Ikegawa S, Jiang Q, Shi D
Journal of orthopaedic translation 2021 Jul;29:89-99
Journal of orthopaedic translation 2021 Jul;29:89-99
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
SHP-1 suppresses endotoxin-induced uveitis by inhibiting the TAK1/JNK pathway.
Zhuang X, Ma J, Xu S, Sun Z, Zhang R, Zhang M, Xu G
Journal of cellular and molecular medicine 2021 Jan;25(1):147-160
Journal of cellular and molecular medicine 2021 Jan;25(1):147-160
Sporoderm-Removed Ganoderma lucidum Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway.
Liu G, Zeng T
Integrative cancer therapies 2021 Jan-Dec;20:15347354211062157
Integrative cancer therapies 2021 Jan-Dec;20:15347354211062157
CREBBP/EP300 mutations promoted tumor progression in diffuse large B-cell lymphoma through altering tumor-associated macrophage polarization via FBXW7-NOTCH-CCL2/CSF1 axis.
Huang YH, Cai K, Xu PP, Wang L, Huang CX, Fang Y, Cheng S, Sun XJ, Liu F, Huang JY, Ji MM, Zhao WL
Signal transduction and targeted therapy 2021 Jan 11;6(1):10
Signal transduction and targeted therapy 2021 Jan 11;6(1):10
Disruption of P2X4 purinoceptor and suppression of the inflammation associated with cerebral aneurysm formation.
Fukuda M, Fukuda S, Ando J, Yamamoto K, Yonemoto N, Suzuki T, Niwa Y, Inoue T, Satoh-Asahara N, Hasegawa K, Shimatsu A, Tsukahara T
Journal of neurosurgery 2021 Jan 1;134(1):102-114
Journal of neurosurgery 2021 Jan 1;134(1):102-114
YY1 promotes SOCS3 expression to inhibit STAT3‑mediated neuroinflammation and neuropathic pain.
Sun M, Sun Y, Ma J, Li K
Molecular medicine reports 2021 Feb;23(2)
Molecular medicine reports 2021 Feb;23(2)
Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response.
Amin R, Shukla A, Zhu JJ, Kim S, Wang P, Tian SZ, Tran AD, Paul D, Cappell SD, Burkett S, Liu H, Lee MP, Kruhlak MJ, Dwyer JE, Simpson RM, Hager GL, Ruan Y, Hunter KW
Nature communications 2021 Dec 13;12(1):7216
Nature communications 2021 Dec 13;12(1):7216
Tubeimoside I protects against sepsis-induced cardiac dysfunction via SIRT3.
Cheng Z, Lv D, Luo M, Wang R, Guo Y, Yang X, Huang L, Li X, Li C, Shang FF, Huang B, Shen J, Luo S, Yan J
European journal of pharmacology 2021 Aug 15;905:174186
European journal of pharmacology 2021 Aug 15;905:174186
Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage.
Balzano T, Leone P, Ivaylova G, Castro MC, Reyes L, Ramón C, Malaguarnera M, Llansola M, Felipo V
Biomedicines 2021 Aug 12;9(8)
Biomedicines 2021 Aug 12;9(8)
Bio-inspired chiral self-assemblies promoted neuronal differentiation of retinal progenitor cells through activation of metabolic pathway.
Sun N, Dou X, Tang Z, Zhang D, Ni N, Wang J, Gao H, Ju Y, Dai X, Zhao C, Gu P, Ji J, Feng C
Bioactive materials 2021 Apr;6(4):990-997
Bioactive materials 2021 Apr;6(4):990-997
WJ-39, an Aldose Reductase Inhibitor, Ameliorates Renal Lesions in Diabetic Nephropathy by Activating Nrf2 Signaling.
Zhou X, Liu Z, Ying K, Wang H, Liu P, Ji X, Chi T, Zou L, Wang S, He Z
Oxidative medicine and cellular longevity 2020;2020:7950457
Oxidative medicine and cellular longevity 2020;2020:7950457
Ketogenic diet aggravates cardiac remodeling in adult spontaneously hypertensive rats.
You Y, Guo Y, Jia P, Zhuang B, Cheng Y, Deng H, Wang X, Zhang C, Luo S, Huang B
Nutrition & metabolism 2020;17:91
Nutrition & metabolism 2020;17:91
Transcriptome Analysis Revealed Inflammation Is Involved in the Impairment of Human Umbilical Vein Endothelial Cells Induced by Post-hemorrhagic Shock Mesenteric Lymph.
Wang Q, Chi ZF, Wei D, Zhao ZA, Zhang H, Zhang LM, Liu YX, Kang AL, Zhao M, Wang P, Nie LH, Niu CY, Zhao ZG
Frontiers in immunology 2020;11:1717
Frontiers in immunology 2020;11:1717
Blockage of C-C Chemokine Ligand 2 Alleviated the Appendicitis-Induced Injury in Rabbit Model.
Liu W, Zeng A, Tang H, Qiang J
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Sep;40(9):446-453
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Sep;40(9):446-453
Suppression of microglial activation and monocyte infiltration ameliorates cerebellar hemorrhage induced-brain injury and ataxia.
Xie ST, Chen AX, Song B, Fan J, Li W, Xing Z, Peng SY, Zhang QP, Dong L, Yan C, Zhang XY, Wang JJ, Zhu JN
Brain, behavior, and immunity 2020 Oct;89:400-413
Brain, behavior, and immunity 2020 Oct;89:400-413
Downregulation of G3BP2 reduces atherosclerotic lesions in ApoE(-/-) mice.
Li T, Safitri M, Zhang K, Wang Y, Huang L, Zhu Y, Daniel R, Wu LJ, Qiu J, Wang G
Atherosclerosis 2020 Oct;310:64-74
Atherosclerosis 2020 Oct;310:64-74
Cross-talk between the gut microbiota and monocyte-like macrophages mediates an inflammatory response to promote colitis-associated tumourigenesis.
Yang Y, Li L, Xu C, Wang Y, Wang Z, Chen M, Jiang Z, Pan J, Yang C, Li X, Song K, Yan J, Xie W, Wu X, Chen Z, Yuan Y, Zheng S, Yan J, Huang J, Qiu F
Gut 2020 Oct 29;70(8):1495-506
Gut 2020 Oct 29;70(8):1495-506
Cortistatin protects against inflammatory airway diseases through curbing CCL2 and antagonizing NF-κB signaling pathway.
Qiu C, Li J, Luo D, Chen X, Qu R, Liu T, Li F, Liu Y
Biochemical and biophysical research communications 2020 Oct 22;531(4):595-601
Biochemical and biophysical research communications 2020 Oct 22;531(4):595-601
Neuronal/astrocytic expression of chemokine (C-C motif) ligand 2 is associated with monocyte/macrophage recruitment in male chronic pelvic pain.
Liu Z, Murphy SF, Wong L, Schaeffer AJ, Thumbikat P
Pain 2020 Nov;161(11):2581-2591
Pain 2020 Nov;161(11):2581-2591
Non-neuronal crosstalk promotes an inflammatory response in nodose ganglia cultures after exposure to byproducts from gram positive, high-fat-diet-associated gut bacteria.
Cawthon CR, Kirkland RA, Pandya S, Brinson NA, de La Serre CB
Physiology & behavior 2020 Nov 1;226:113124
Physiology & behavior 2020 Nov 1;226:113124
Interplay between cancer cells and M2 macrophages is necessary for miR-550a-3-5p down-regulation-mediated HPV-positive OSCC progression.
Cao MX, Zhang WL, Yu XH, Wu JS, Qiao XW, Huang MC, Wang K, Wu JB, Tang YJ, Jiang J, Liang XH, Tang YL
Journal of experimental & clinical cancer research : CR 2020 Jun 3;39(1):102
Journal of experimental & clinical cancer research : CR 2020 Jun 3;39(1):102
Major depression accompanied with inflammation and multiple cytokines alterations: Evidences from clinical patients to macaca fascicularis and LPS-induced depressive mice model.
He Y, Li W, Wang Y, Tian Y, Chen X, Wu Z, Lan T, Li Y, Bai M, Liu J, Cheng K, Xie P
Journal of affective disorders 2020 Jun 15;271:262-271
Journal of affective disorders 2020 Jun 15;271:262-271
Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells.
Yang F, Li S, Cheng Y, Li J, Han X
Life sciences 2020 Jul 1;252:117611
Life sciences 2020 Jul 1;252:117611
Glibenclamide ameliorates transplant-induced arteriosclerosis and inhibits macrophage migration and MCP-1 expression.
Zou Y, Zhou C, Xu H, Yu J, Ye P, Zhang H, Chen S, Zhao J, Le S, Cui J, Jiang L, Wu J, Xia J
Life sciences 2020 Jan 15;241:117141
Life sciences 2020 Jan 15;241:117141
PP2A alleviates oxidized LDL-induced endothelial dysfunction by regulating LOX-1/ROS/MAPK axis.
Xu K, Liu X, Yin D, Ren G, Zhao Y
Life sciences 2020 Feb 15;243:117270
Life sciences 2020 Feb 15;243:117270
Acupuncture reduces pain in rats with osteoarthritis by inhibiting MCP2/CCR2 signaling pathway.
Li B, Jing L, Jia L, Qian T, Jianyi C, Zhongsheng H, Xiaohong Z, Guowei C
Experimental biology and medicine (Maywood, N.J.) 2020 Dec;245(18):1722-1731
Experimental biology and medicine (Maywood, N.J.) 2020 Dec;245(18):1722-1731
Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission.
Ma D, Zheng B, Liu HL, Zhao YB, Liu X, Zhang XH, Li Q, Shi WB, Suzuki T, Wen JK
PLoS biology 2020 Aug;18(8):e3000808
PLoS biology 2020 Aug;18(8):e3000808
Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway.
Gao F, Zuo B, Wang Y, Li S, Yang J, Sun D
Life sciences 2020 Aug 15;255:117719
Life sciences 2020 Aug 15;255:117719
Louqin Zhisou Decoction Inhibits Mucus Hypersecretion for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Rats by Suppressing EGFR-PI3K-AKT Signaling Pathway and Restoring Th17/Treg Balance.
Feng F, Du J, Meng Y, Guo F, Feng C
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6471815
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6471815
β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway.
Yu X, Li Z, Zhang Y, Xu M, Che Y, Tian X, Wang R, Zou K, Zou L
OncoTargets and therapy 2019;12:4203-4211
OncoTargets and therapy 2019;12:4203-4211
MiR-143-3p directly targets GLUT9 to reduce uric acid reabsorption and inflammatory response of renal tubular epithelial cells.
Zhou Z, Dong Y, Zhou H, Liu J, Zhao W
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Biochemical and biophysical research communications 2019 Sep 24;517(3):413-420
Transcriptomes in rat sciatic nerves at different stages of experimental autoimmune neuritis determined by RNA sequencing.
Xue Y, Yin P, Li G, Zhong D
Clinical and experimental immunology 2019 Nov;198(2):184-197
Clinical and experimental immunology 2019 Nov;198(2):184-197
Inflammation induced by incomplete radiofrequency ablation accelerates tumor progression and hinders PD-1 immunotherapy.
Shi L, Wang J, Ding N, Zhang Y, Zhu Y, Dong S, Wang X, Peng C, Zhou C, Zhou L, Li X, Shi H, Wu W, Long X, Wu C, Liao W
Nature communications 2019 Nov 28;10(1):5421
Nature communications 2019 Nov 28;10(1):5421
Autologous nanofat transplantation accelerates foot wound healing in diabetic rats.
Chen L, Wang ZC, Ma JJ, Sun WJ, Wang SW, Gu ZC, Yang X
Regenerative medicine 2019 Mar;14(3):231-241
Regenerative medicine 2019 Mar;14(3):231-241
Administration of methyl palmitate prevents non-alcoholic steatohepatitis (NASH) by induction of PPAR-α.
Zhang L, Li HX, Pan WS, Ullah Khan F, Qian C, Qi-Li FR, Xu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:99-108
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Mar;111:99-108
Clock mutant promotes osteoarthritis by inhibiting the acetylation of NFκB.
Yuan G, Xu L, Cai T, Hua B, Sun N, Yan Z, Lu C, Qian R
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Osteoarthritis and cartilage 2019 Jun;27(6):922-931
Repair Effects of Astragalus Polysaccharides with Different Molecular Weights on Oxidatively Damaged HK-2 Cells.
Han J, Guo D, Sun XY, Wang JM, Ouyang JM, Gui BS
Scientific reports 2019 Jul 8;9(1):9871
Scientific reports 2019 Jul 8;9(1):9871
LncRNA NKILA regulates endothelium inflammation by controlling a NF-κB/KLF4 positive feedback loop.
Zhu X, Du J, Yu J, Guo R, Feng Y, Qiao L, Xu Z, Yang F, Zhong G, Liu F, Cheng F, Chu M, Lin J
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
Journal of molecular and cellular cardiology 2019 Jan;126:60-69
The P2Y(14) receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain.
Lin J, Zhang YY, Liu F, Fang XY, Liu MK, Huang CL, Wang H, Liao DQ, Zhou C, Shen JF
Neurochemistry international 2019 Dec;131:104567
Neurochemistry international 2019 Dec;131:104567
BpV(pic) confers neuroprotection by inhibiting M1 microglial polarization and MCP-1 expression in rat traumatic brain injury.
Liu R, Liao XY, Tang JC, Pan MX, Chen SF, Lu PX, Lu LJ, Zhang ZF, Zou YY, Bu LH, Qin XP, Wan Q
Molecular immunology 2019 Aug;112:30-39
Molecular immunology 2019 Aug;112:30-39
Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2.
Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, Peng W, Han D, Zhou X, Wu J, He H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Apr;112:108669
Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice.
Li X, Jia L, Chen X, Dong Y, Ren X, Dong Y, Chen Y, Xie L, Liu M, Shiota C, Gittes GK, Rui L, Chen Z
Theranostics 2018;8(21):5960-5971
Theranostics 2018;8(21):5960-5971
Salusin-β Is Involved in Diabetes Mellitus-Induced Endothelial Dysfunction via Degradation of Peroxisome Proliferator-Activated Receptor Gamma.
Sun HJ, Chen D, Wang PY, Wan MY, Zhang CX, Zhang ZX, Lin W, Zhang F
Oxidative medicine and cellular longevity 2017;2017:6905217
Oxidative medicine and cellular longevity 2017;2017:6905217
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Liu Q, Du Y, Li K, Zhang W, Feng X, Hao J, Li H, Liu S
Mediators of inflammation 2017;2017:3038514
Mediators of inflammation 2017;2017:3038514
Effects of crenolanib, a nonselective inhibitor of PDGFR, in a mouse model of transient middle cerebral artery occlusion.
Wang J, Fu X, Zhang D, Yu L, Lu Z, Gao Y, Liu X, Man J, Li S, Li N, Wang M, Liu X, Chen X, Zang W, Yang Q, Wang J
Neuroscience 2017 Nov 19;364:202-211
Neuroscience 2017 Nov 19;364:202-211
Glucocorticoid-Induced Leucine Zipper Suppresses ICAM-1 and MCP-1 Expression by Dephosphorylation of NF-κB p65 in Retinal Endothelial Cells.
Gu R, Lei B, Jiang C, Xu G
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
Investigative ophthalmology & visual science 2017 Jan 1;58(1):631-641
The role of TGF-β-activated kinase 1 in db/db mice and high glucose-induced macrophage.
Xu X, Fan Z, Qi X, Shao Y, Wu Y
International immunopharmacology 2016 Sep;38:120-31
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