505901
antibody from BioLegend
Targeting: CCL2
GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF
Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations [0]
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- Product number
- 505901 - Provider product page

- Provider
- BioLegend
- Proper citation
- BioLegend Cat#505901, RRID:AB_315407
- Product name
- Purified anti-mouse/rat/human MCP-1
- Antibody type
- Monoclonal
- Antigen
- CHO-expressed, recombinant mouse MCP-1
- Description
- Monocyte chemotactic protein-1 (MCP-1) also known as monocyte chemotactic and activating factor (MCAF) was identified based on its ability to chemoattract monocytes. Subsequently, MCP-1 has also been found to regulate adhesion molecule expression and cytokine production in monocytes. MCP-1 is identical to the product of the JE gene, a PDGF inducible gene. MCP-1 is a member of the beta (C-C) chemokine subfamily, known as CCL2. The 2H5 antibody reacts with mouse, rat, and human MCP-1. The 2H5 antibody can neutralize the bioactivity of natural or recombinant MCP-1.
- Reactivity
- Human, Mouse, Rat
- Host
- Hamster
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 50 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Early focal expression of the chemokine Ccl2 by Müller cells during exposure to damage-inducing bright continuous light.
Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment.
Rutar M, Natoli R, Valter K, Provis JM
Investigative ophthalmology & visual science 2011 Apr;52(5):2379-88
Investigative ophthalmology & visual science 2011 Apr;52(5):2379-88
Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment.
Patsouris D, Neels JG, Fan W, Li PP, Nguyen MT, Olefsky JM
The Journal of biological chemistry 2009 Nov 6;284(45):31223-35
The Journal of biological chemistry 2009 Nov 6;284(45):31223-35
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