Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 12885-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12885-1-AP, RRID:AB_2114762
- Product name
- GSDMB antibody
- Antibody type
- Polyclonal
- Description
- GSDMB antibody (Cat. #12885-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Expression profile of GSDMB in oral squamous cell carcinoma and its impact on tumor immune microenvironment and prognosis.
GATA1 promotes TGF-β1-induced epithelial-mesenchymal transition by regulating GSDMB in human bronchial epithelial cells.
Epigenetic regulation of IPF fibroblast phenotype by glutaminolysis.
Clinical-mediated discovery of pyroptosis in CD8(+) T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence.
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma.
Novel Pyroptosis-Related Gene Signatures Identified as the Prognostic Biomarkers for Bladder Carcinoma.
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.
Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts.
A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.
Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation.
Cui Z, Gao Y, Yang K, Dong Z
BMC oral health 2026 Jan 30;26(1)
BMC oral health 2026 Jan 30;26(1)
GATA1 promotes TGF-β1-induced epithelial-mesenchymal transition by regulating GSDMB in human bronchial epithelial cells.
Li JJ, Chen JH, Yuan Y, Li L, Zhou C, Chen H, Geng J, Cao Q, Jin R
Molecular immunology 2025 Nov;187:229-239
Molecular immunology 2025 Nov;187:229-239
Epigenetic regulation of IPF fibroblast phenotype by glutaminolysis.
Xiang Z, Bai L, Zhou JQ, Cevallos RR, Sanders JR, Liu G, Bernard K, Sanders YY
Molecular metabolism 2023 Jan;67:101655
Molecular metabolism 2023 Jan;67:101655
Clinical-mediated discovery of pyroptosis in CD8(+) T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence.
Zhang Y, Bai Y, Ma XX, Song JK, Luo Y, Fei XY, Ru Y, Luo Y, Jiang JS, Zhang Z, Yang D, Xue TT, Zhang HP, Liu TY, Xiang YW, Kuai L, Liu YQ, Li B
Cell death & disease 2023 Aug 24;14(8):553
Cell death & disease 2023 Aug 24;14(8):553
Schisandrin B induces HepG2 cells pyroptosis by activating NK cells mediated anti-tumor immunity.
Song A, Ding T, Wei N, Yang J, Ma M, Zheng S, Jin H
Toxicology and applied pharmacology 2023 Aug 1;472:116574
Toxicology and applied pharmacology 2023 Aug 1;472:116574
Crosstalk of necroptosis and pyroptosis defines tumor microenvironment characterization and predicts prognosis in clear cell renal carcinoma.
Fu L, Bao J, Li J, Li Q, Lin H, Zhou Y, Li J, Yan Y, Langston ME, Sun T, Guo S, Zhou X, Chen Y, Liu Y, Zhao Y, Lu J, Huang Y, Chen W, Chung BI, Luo J
Frontiers in immunology 2022;13:1021935
Frontiers in immunology 2022;13:1021935
Novel Pyroptosis-Related Gene Signatures Identified as the Prognostic Biomarkers for Bladder Carcinoma.
You J, Li H, Wei Y, Fan P, Zhao Y, Yi C, Guo Q, Yang X
Frontiers in oncology 2022;12:881860
Frontiers in oncology 2022;12:881860
USP24-GSDMB complex promotes bladder cancer proliferation via activation of the STAT3 pathway.
He H, Yi L, Zhang B, Yan B, Xiao M, Ren J, Zi D, Zhu L, Zhong Z, Zhao X, Jin X, Xiong W
International journal of biological sciences 2021;17(10):2417-2429
International journal of biological sciences 2021;17(10):2417-2429
Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts.
Bai L, Bernard K, Tang X, Hu M, Horowitz JC, Thannickal VJ, Sanders YY
American journal of respiratory cell and molecular biology 2019 Jan;60(1):49-57
American journal of respiratory cell and molecular biology 2019 Jan;60(1):49-57
A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis.
Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q
The Journal of allergy and clinical immunology 2018 Nov;142(5):1469-1478.e2
The Journal of allergy and clinical immunology 2018 Nov;142(5):1469-1478.e2
Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation.
Bernard K, Logsdon NJ, Benavides GA, Sanders Y, Zhang J, Darley-Usmar VM, Thannickal VJ
The Journal of biological chemistry 2018 Jan 26;293(4):1218-1228
The Journal of biological chemistry 2018 Jan 26;293(4):1218-1228
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 12885-1-AP( GSDMB Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human stomach cancer using 12885-1-AP(GSDMB antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GSDMB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GSDMB. This antibody recognizes human antigen. The GSDMB antibody has been validated for the following applications: ELISA, IHC, WB analysis.
