CABT-B11093

antibody from Creative Diagnostics

Targeting: PTCH1 BCNS, NBCCS, PTCH

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

CABT-B11093

Provider

Creative Diagnostics

Product name

Mouse anti-Human PTCH1 monoclonal antibody, clone 2H3

Antibody type

Monoclonal

Description

This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2H3

Vial size

100 _g

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.