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- Antibody Data
- Antigen structure
- References [7]
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- Western blot [1]
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- Product number
- NB110-40561 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-40561, RRID:AB_2171208
- Product name
- Rabbit Polyclonal LEDGF Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Development and validation of a cell-based assay system to assess human immunodeficiency virus type 1 integrase multimerization.
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.
Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.
Pathway specific gene expression profiling reveals oxidative stress genes potentially regulated by transcription co-activator LEDGF/p75 in prostate cancer cells.
The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity.
Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting.
High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region.
Nakamura T, Campbell JR, Moore AR, Otsu S, Aikawa H, Tamamura H, Mitsuya H
Journal of virological methods 2016 Oct;236:196-206
Journal of virological methods 2016 Oct;236:196-206
Psip1/Ledgf p52 binds methylated histone H3K36 and splicing factors and contributes to the regulation of alternative splicing.
Pradeepa MM, Sutherland HG, Ule J, Grimes GR, Bickmore WA
PLoS genetics 2012;8(5):e1002717
PLoS genetics 2012;8(5):e1002717
Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.
Desimmie BA, Humbert M, Lescrinier E, Hendrix J, Vets S, Gijsbers R, Ruprecht RM, Dietrich U, Debyser Z, Christ F
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Nov;20(11):2064-75
Molecular therapy : the journal of the American Society of Gene Therapy 2012 Nov;20(11):2064-75
Pathway specific gene expression profiling reveals oxidative stress genes potentially regulated by transcription co-activator LEDGF/p75 in prostate cancer cells.
Basu A, Drame A, Muñoz R, Gijsbers R, Debyser Z, De Leon M, Casiano CA
The Prostate 2012 May 1;72(6):597-611
The Prostate 2012 May 1;72(6):597-611
The stress oncoprotein LEDGF/p75 interacts with the methyl CpG binding protein MeCP2 and influences its transcriptional activity.
Leoh LS, van Heertum B, De Rijck J, Filippova M, Rios-Colon L, Basu A, Martinez SR, Tungteakkhun SS, Filippov V, Christ F, De Leon M, Debyser Z, Casiano CA
Molecular cancer research : MCR 2012 Mar;10(3):378-91
Molecular cancer research : MCR 2012 Mar;10(3):378-91
Role of the PWWP domain of lens epithelium-derived growth factor (LEDGF)/p75 cofactor in lentiviral integration targeting.
Gijsbers R, Vets S, De Rijck J, Ocwieja KE, Ronen K, Malani N, Bushman FD, Debyser Z
The Journal of biological chemistry 2011 Dec 2;286(48):41812-25
The Journal of biological chemistry 2011 Dec 2;286(48):41812-25
High-resolution profiling of the LEDGF/p75 chromatin interaction in the ENCODE region.
De Rijck J, Bartholomeeusen K, Ceulemans H, Debyser Z, Gijsbers R
Nucleic acids research 2010 Oct;38(18):6135-47
Nucleic acids research 2010 Oct;38(18):6135-47
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: LEDGF Antibody [NB110-40561] - Detection of Human LEDGF/p75 on HeLa whole cell lysate using NB110-40561. LEDGF/p75 was also immunoprecipitated by another rabbit anti-LEDGF/p75 antibody.
