HPA038914

antibody from Atlas Antibodies

Targeting: PACS1 FLJ10209, KIAA1175

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

HPA038914

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA038914, RRID:AB_10672831

Product name

Anti-PACS1

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human PACS1, Gene description: phosphofurin acidic cluster sorting protein 1, Alternative Gene Names: FLJ10209, KIAA1175, Validated applications: IHC, ICC, Uniprot ID: Q6VY07, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

iPSC-derived models of PACS1 syndrome reveal transcriptional and functional deficits in neuron activity.

Rylaarsdam L, Rakotomamonjy J, Pope E, Guemez-Gamboa A
Nature communications 2024 Jan 27;15(1):827

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The multifunctional protein PACS-1 is required for HDAC2- and HDAC3-dependent chromatin maturation and genomic stability

Mani C, Tripathi K, Luan S, Clark D, Andrews J, Vindigni A, Thomas G, Palle K
Oncogene 2020;39(12):2583-2596

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human cerebral cortex and liver tissues using HPA038914 antibody. Corresponding PACS1 RNA-seq data are presented for the same tissues.

Sample type

Human

Protocol

Protocol

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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