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- Product number
- 22401-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ACSL4/FACL4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ACSL4/FACL4 antibody (Cat. #22401-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references IL-22 inhibits ferroptosis and attenuates ischemia-reperfusion-induced acute kidney injury: Association with activation of the P62-Keap1-Nrf2 signaling pathway.
Chondroitin sulfate alleviates osteoarthritis by upregulating HSPA8 to inhibit chondrocyte ferroptosis.
Monitoring early micro-oxidation under refrigeration: iron and oxidative markers predict quality loss in grass carp.
Multifunctional selenium nanoplatforms for synergistic ferroptosis inhibition and immune microenvironment remodeling in oral mucositis.
A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
NRH attenuates age-related hearing loss by suppressing cochlear ferroptosis and cellular senescence via Sirt3 activation.
NCOA4-mediated ferroptosis drives cGAS-STING-dependent inflammation in radiation dermatitis: Protective modulation by Cu-ATSM.
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.
g-C(3)N(4) Nanosheets as a Ferroptosis-Targeted Nanoprobe: Mitigating Iron Overload and Restoring Male Fertility via Nrf2 Pathway Activation.
Yitangkang decoction in the treatment of glomerular filtration barrier damage through AMPKα1/ZDHHC8/SLC7A11/GPX4 and TGF-β/Smad signaling pathways: A multi-omics analysis.
Qiangji Jianli Decoction attenuates skeletal muscle injury in rats with experimental autoimmune myasthenia gravis via the GRP78/IRE1α/GPX4 signaling pathway.
Naringenin inhibits Ferroptosis and ameliorates interstitial cystitis with metabolic syndrome by activating the Nrf2/NQO-1 pathway.
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.
Andrographolide blocked the progression of endometriosis by promoting ferroptosis via inhibiting anabolism of serine.
AARS1-mediated lactylation of H3K18 and STAT1 promotes ferroptosis in diabetic nephropathy.
Rhein-Emodin Combination Activates UQCRC1 to Attenuate MPP(+)-Induced Ferroptosis in Dopaminergic Neurons.
M2 macrophage-derived exosome nanoplatform for targeted H(2)S delivery to alleviate hepatic ischemia-reperfusion injury via synergistic anti-oxidative, anti-inflammatory, and anti-ferroptotic effects.
RBM3-mediated m6A modification of KLF6 promotes ACSL4-driven ferroptosis in ulcerative colitis.
Sertad1 exacerbates cardiomyocytes ferroptosis in sepsis-induced myocardial injury by inhibiting HIPK2.
Boron Triggers Hepatic Ferroptosis: Unveiling the Dual-Pathogenic Nexus of Oxidative Stress and SLC7A11/GPX4 Dysregulation.
Targeting SLC6A8 suppresses tumor growth and enhances ferroptosis in hepatocellular carcinoma.
TIMP3 Suppresses Oxidative Stress and Ferroptosis of Lens Epithelial Cells in Cataract Through Regulating the Keap1/Nrf2 Pathway.
Systemic Oxidative Stress and Oxidized Albumin Mediate the Pathogenic Kidney-to-Gut Crosstalk by Disrupting Intestinal Barrier Integrity.
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Microneedle patches deliver targeted GLP-1RAs-loaded nanoparticles for the treatment of rheumatoid arthritis.
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
CXCL12 Promotes Peripheral Nerve Injury Repair by Inhibiting the Ferroptosis-Inflammation Axis via the ERK/Nrf2 Pathway.
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
Cell size modulates ferroptosis susceptibility.
Membrane-translocated SO₂/₃-PRDX3 disrupts cystine uptake and GPX4 activity: A pivotal mechanism of boron-induced renal ferroptosis in broiler.
Paeoniflorin mitigates myocardial hypertrophy by regulating mitophagy and ferroptosis mediated by mitochondria-associated AMPK-Parkin-ACSL4 pathway.
A spinal USP7-Bach1 positive feedback loop drives NOX4-mediated ferroptosis in neuropathic pain.
A mitochondria-targeted nanoantioxidant restores alveolar bone homeostasis in periodontitis by quenching ROS and suppressing the cGAS-STING pathway.
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
ZDBF2/SIRT6-mediated H3K27 deacetylation inhibits ferroptosis and reduces sensitivity of oral squamous cell carcinoma to cisplatin.
Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR-217/SIRT1/Nrf2 pathway.
Shunaoxin dropping pills alleviate cerebral ischemia-reperfusion injury in MCAO rats associated with ferroptosis inhibition and AKT/Nrf2/HO-1 pathway activation.
Momordin Ic targets SREBP1 to disrupt lipid homeostasis and trigger synergistic apoptosis-ferroptosis in triple-negative breast cancer.
Copper potentiates PUFA-mediated antitumor activity by activating Lipophagy.
Therapeutic mechanism of Changyong Decoction in suppressing colorectal cancer progression and inducing ferroptosis via the PIEZO1-PI3K/AKT signaling axis.
Kaempferide alleviates glucocorticoid-induced osteoporosis by targeting ferroptosis through the GSK3β/Nrf-2/GPX4 pathway.
Synergistic induction of ferroptosis by paclitaxel and sunitinib is mediated through SLC7A11 in lung cancer.
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
Pyrvinium pamoate inhibits the survival of intracellular Mycobacterium tuberculosis through suppression of macrophage ferroptosis.
Sodium Houttuyfonate improves cognitive impairment in mice after chronic sleep deprivation by inhibiting microglial inflammation and ferroptosis.
Loss of cGAS facilitates angiogenesis in diabetic foot ulcer healing by suppressing the STING/ferroptosis pathway.
Identifying cathepsin B as a key regulator of programmed cell death in acute pancreatitis.
The CHPT-pSTAT3-SLC7A11 signaling axis controls progression and ferroptosis susceptibility of pancreatic cancer.
The METTL3/IGF2BP1 axis-mediated m6 A modification of TRIM11 mRNA suppresses ferroptosis and accelerates malignant progression in non-small cell lung cancer cells by degrading ACSL4.
N6-methyladenosine (m(6)A) modification regulates LONP1 to inhibit coxsackievirus B3 replication by suppressing virus-induced ferroptosis.
MC1R contributes to ferroptosis resistance and tumor aggressiveness in colorectal cancer by activating Notch signaling.
Resveratrol can inhibit porcine reproductive and respiratory syndrome virus infection in vitro and in vivo by inhibiting PI3K/Akt signaling pathway.
Eugenol attenuates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the Nrf2/GPX4 pathway.
Unveiling Novel Biomarkers: Ferroptosis and m1A in the Progression of Nanographene-Induced Lung Fibrosis.
Integrated proteomic and metabolomic analysis reveals lipid metabolic dysregulation and ferroptosis as potential drivers of placental dysfunction in intrahepatic cholestasis of pregnancy.
Fisetin Ameliorates Vascular Calcification by Regulating HNRNPA1-Mediated Ferroptosis.
Renal-targeted exosomes inhibiting miR-182-5p for treatment of renal ischemia-reperfusion injury.
Methotrexate-triggered ferroptosis suppresses oral cancer progression by phosphorylated KEAP1-mediated NRF2 degradation to inhibit SLC7A11/GPX4 signaling pathway.
Cucurbitacin B Inhibits Hepatocellular Carcinoma by Inducing Ferroptosis and Activating the cGAS-STING Pathway.
Betaine Inhibits Ferroptosis After Intracerebral Hemorrhage by Activating the Nrf2/HO-1 Pathway.
Moscatilin alleviates severe acute pancreatitis by activating the NRF2/HO-1 pathway to inhibit ferroptosis.
SREBP2 confers ferroptosis resistance by targeting GPX4 in colorectal cancer.
Licochalcone D modulates macrophage ferroptosis via suppression of VPS4A-mediated lipophagy to alleviate MRSA pneumonia.
Soufeng Yuchuan formula alleviates asthma airway inflammation and suppresses the progression of asthma by inhibiting ferroptosis in airway epithelial cells.
Overexpression of OTUD5 in IPSCs-derived extracellular vesicles promotes angiogenesis after myocardial infarction by inhibiting endothelial cell ferroptosis.
An activatable polymeric nano-spy for reversing the progression of diabetic osteoporosis.
Progesterone receptor membrane component 1 (PGRMC1) regulates Heme trafficking through mitochondria-ER junctions.
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Curcumin pretreatment enhances the capacity of BMSC exosomes to attenuate renal ischemia-reperfusion injury by ferroptosis suppression via miR-16-5p/Smad3/Mb axis.
SIRT1-mediated FABP4 destabilization attenuates fibrosis and ferroptosis in non-alcoholic fatty liver disease.
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism.
METTL3-mediated m6A modification of TIFA mRNA promotes tubular cell pyroptosis in acute kidney injury.
Carboxymethyl chitosan-based injectable hydrogel immobilizing single-atom nanozymes for localized ROS amplification and ferroptosis-enhanced postoperative oral cancer therapy.
Multi-omics unravels multiple pharmacological actions in a murine model of infantile hemangioma receiving oxymatrine therapy.
Low, plasma level‑informed native curcumin concentrations fail to induce cell death in human lung and colorectal cancer cells.
lncRNA MALAT1-mediated regulation of cholesterol-oxidative stress-iron metabolic dysregulation by paeoniflorin in osteoarthritic chondrocytes.
EP300 attenuates ferroptosis and stimulates proliferation, migration, and fibrosis of keloid fibroblasts via YY1/GPX4 axis.
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
NUPR1 and LCN2: Potential Therapeutic Targets for Colorectal Cancer Via Modulating Cell Viability, Migration, and Ferroptosis-Related Pathways.
Application of a novel myristoylproteomics approach identifies GLIPR2 as a key pro-ferroptotic substrate in non-small cell lung cancer.
Puerarin promotes nerve regeneration and functional recovery after peripheral nerve injury by inhibiting ACSL4-dependent ferroptosis.
NRF2-TERT-ACSL4 pathway inhibits ferroptosis and regulates cytoskeletal dynamics to mitigate ovarian aging.
Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4-Mediated Ferroptosis.
Resveratrol dual efficacy in high-altitude hypoxia and NAFLD: inhibits ferroptosis by modulating key proteins, including HIF-1α, ACSL4, and TfR1.
Apigenin-5-O-glucoside alleviates hepatic fibrosis through NOX4-mediated ferroptosis in zebrafish.
Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
PDK4 acts via hippo signaling to inhibit ferroptosis and reduce gemcitabine sensitivity in pancreatic cancer.
Downregulation of SELENOS Suppresses the Progression of Renal Cell Carcinoma by Activating Ferroptosis.
Genome-wide CRISPR screen identifies TAF1C as an epigenetic determinant of lipid deposition via ACSL4-dependent ferroptosis in MASLD.
Aberrant expression of TRIM26 suppresses ferroptosis through regulating GPX4 protein stability in colorectal cancer.
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates diabetic nephropathy via suppressing SLC7A11-mediated ferroptosis.
USP53 Drives Ethanol-Induced Myocardial Injury by Promoting K63 Deubiquitination-Dependent RIPK1 Activation at K377.
H2S inhibits high glucose-induced osteoblast injury by inhibiting ferroptosis in diabetic osteoporosis in vitro.
PROTAC-Surufatinib Suppresses Pancreatic Neuroendocrine Neoplasms Progression by Inducing Ferroptosis through Inhibiting WNT/β-catenin Pathway Mediated by HMOX1.
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Pan-cancer analysis and validation show GTF2E2's diagnostic, prognostic, and immunological roles in regulating ferroptosis in endometrial cancer.
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
Self-Assembled Carrier Free Oligomeric Proanthocyanidin/Tetrandrine Nanoparticles Ameliorate Osteoarthritis via Anti-Inflammatory and Anti-Ferroptotic Pathways.
MXene-Mediated Nanocarrier Delivery Enhances the Chondroprotective Effects of Quercetin in Experimental Osteoarthritis.
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation.
Ferroptosis-related genes as prognostic markers for survival and immunotherapy in triple-negative breast cancer: analysis of public databases and a single institution.
Exploring the mechanism of Qingre Yishen Xiaozheng formula in treating diabetic kidney disease via the HIF-1α/HO-1 signaling pathway: an integrated network pharmacology and experimental study.
Integrating network analysis and experimental validation to reveal the ferroptosis-associated mechanism of acteoside in the treatment of diabetic nephropathy.
Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma.
Pan-cancer analysis reveals MTTP as a prognostic and immunotherapeutic biomarker in human tumors.
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation.
Gallic acid protects intervertebral disc cells from ferroptosis and alleviates intervertebral disc degeneration by regulating key factors of oxidative stress.
Bioactive natural alkaloid 6-Methoxydihydrosanguinarine exerts anti-tumor effects in hepatocellular carcinoma cells via ferroptosis.
Integrating oxygen-boosted sonodynamic therapy and ferroptosis via engineered exosomes for effective cancer treatment.
Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
Modified Sanjia Powder ameliorates cognitive impairment and exerts neuroprotective effects in 5 × FAD mice: insights from quantitative proteomics.
Bioinformatic analysis, clinical implications and experimental validation of ferroptosis-related feature gene in IgA nephropathy: focus on DUSP1.
Down-regulation of PCK2 enhanced the radioresistance phenotype of nasopharyngeal carcinoma.
The role and mechanism of PGC-1α in oxLDL-induced ferroptosis of vascular endothelial cells.
Microplastic exposure induces preeclampsia-like symptoms via HIF-1α/TFRC-mediated ferroptosis in placental trophoblast cells.
Gallium maltolate and cisplatin co-treatment effectively targets triple-negative breast cancer in spheroid and mouse models.
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis.
LncRNA 91234.1 targets PRMT1/ASCL4/GPX4 axis to regulate formaldehyde-induced cardiomyocyte ferroptosis and congenital heart disease.
An SPR-based active ingredient recognition strategy for identifying PLK1-targeting withanolides as natural ferroptosis inducers.
Inhibition of Iron Death by Lycium barbarum Polysaccharides Ameliorates Myocardial Injury in Sepsis: A Pharmacological Mechanism Study Based on the NRF2/HO-1 Pathway.
Crotonoside induces ferroptosis and mitochondrial dysfunction in AML.
BRD-K20733377 inhibits ferroptosis and alleviates intervertebral disc degeneration via the STAT3/NFKB1 axis: a multiapproach study.
Yishen Qufeng formula mediates ferroptosis to improve renal fibrosis in unilateral ureteral obstruction rats.
SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer.
3-hydroxyanthranilic acid analog mitigates ischemia-reperfusion injury by inhibiting cardiomyocyte ferroptosis through the activation of Nrf2/HO-1/GPX4.
Dovitinib Ameliorates Inflammation-Related Diseases by Inhibiting Necroptosis and Ferroptosis.
Protective Effect of Hepcidin on Sepsis-Associated Acute Kidney Injury via Activating the Nrf2/GPX4 Signaling Pathway.
Circ_0002638 drives squamous cell lung cancer (LUSC) progression and chemotherapy resistance by inhibiting ferroptosis via SENP1-mediated deSUMOylation of ACSL4.
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
Zearalenone induces intestinal damage and flora disturbance in rats by triggering ferroptosis via the system Xc(-)-GSH-GPX4 signaling pathway.
Sodium tanshinone IIA sulfonate alleviates osteoarthritis through targeting SIRT1.
cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER-Mitochondrial Contacts.
NOX4 Regulates NLRP3 by Inhibiting the Ubiquitination of LRRC8A to Promote Ferroptosis in Nucleus Pulposus Cells.
TSLP mitigates post-infarction myocardial remodeling by promoting eosinophil recruitment and inhibiting JAK1-STAT5-mediated ferroptosis.
Ferritinophagy Is Involved in the Advanced Glycation End Products-Induced Ferroptosis of Vascular Endothelial Cells in Diabetes Mellitus.
Gut microbiota derived butyrate enhances ferroptosis sensitivity in endometriosis through FFAR2/PPAR-γ/PINK1/Parkin mediated mitophagy.
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
TRIM34 inhibits triple-negative breast cancer progression by attenuating fatty acid synthesis via facilitating FASN ubiquitination.
Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the exosome-mediated miR-19b-3p/ACSL4 axis.
Panx3 mediates ferroptosis via the AKT/mTOR signaling pathway in oral squamous cell carcinoma.
Nanovesicles Synergistically Regulate Ferroptosis Characteristic Macrophage-Induced Angiogenesis via Ferritin Heavy Chain 1/Glutathione Peroxidase 4 Pathway to Promote Peripheral Nerve Regeneration.
SLC25A10 promotes cisplatin resistance by inhibiting ferroptosis in cervical cancer.
GSTP1-mediated inhibition of ACSL4-dependent ferroptosis via JNK pathway in DOX-induced cardiomyopathy.
Microwave dynamic therapy induces ferroptosis in colorectal cancer by targeting PTK2B to regulate STAT3-mediated GPX4 expression.
Ginsenoside Ro Targets BCAT1/2 to Suppress Ferroptosis: A Novel Therapeutic Strategy for Ischemic Cardioprotection.
Integrated Multiomic Analysis Reveals the Therapeutic Potential of Danhong Injection in Mitigating Radiation-Induced Heart Disease by Modulating Ferroptosis.
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis.
SPP1 exacerbates ischemic stroke by promoting ferroptosis induced brain injury.
SOCS1 orchestrates ferroptotic renal injury via GPX4 ubiquitination in hyperuricemia.
NDUFA8 promotes cell viability and inhibits ferroptosis and cisplatin sensitivity by stabilizing Fe-S clusters in cervical cancer.
PSAT1 knockdown mediated VDAC1 oligomerization promotes ferroptosis and suppresses cell proliferation in esophageal squamous cell carcinoma.
SPINT2 inhibits NEDD4L-mediated ACSL4 ubiquitination to promote ferroptosis and suppress gallbladder cancer progression.
Structural characterization and functional role of SLC7A6 in GSSG transport and Ferroptosis regulation.
Silymarin ameliorates diet-induced gallstone formation by regulating gut microbiota-derived GCDCA to suppress ferroptosis-ROS-NFκB signaling pathway.
Botulinum Toxin Type A as a Therapeutic Agent in Epilepsy: Attenuation of Neuronal Ferroptosis and Cognitive Dysfunction.
Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis.
Ferroptosis promotes sepsis-related lung injury via endothelial cell senescence.
Cardiomyocyte-specific knockout of Oip5-as1 exacerbates MI/R-induced ferroptosis via p62/KEAP1/NRF2 inhibition.
Palmitic Acid Induces Ferroptosis in Retinal Microvascular Endothelial Cells by Palmitoylation of Keap1 to Affect Diabetic Retinopathy.
Sestrin2 ameliorates LPS-induced cardiomyocyte injury by inhibiting ferroptosis via the Nrf2/HO-1 pathway.
A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunotherapy.
Lipid metabolism-related genes correlate with immune microenvironment and regulate the efficacy of immunotherapy via ferroptosis in melanoma.
ALKBH5-mediated RNA N6-methyladenosine demethylation protects against myocardial I/R-induced injury via FSP1-dependent inhibition of ferroptosis.
B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis.
Chrysin Improves Cognitive Dysfunction in Rats with Intracerebral Hemorrhage by Regulating the Nrf2/GPX4 Pathway to Inhibit Ferroptosis.
Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury.
Ferroptosis-driven neurobehavioral impairment in zebrafish embryos: Mechanistic links to developmental dibutyl phthalate exposure.
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis.
Increased Trophoblast Cell Ferroptosis via HMGB1/ACSL4 Pathway Is Associated with Spontaneous Abortion.
Adipose stem cells ameliorate erectile dysfunction in diabetes mellitus rats by attenuating ferroptosis through NRP1 with SLC7A11 interaction.
Comprehensive analysis of ferroptosis-related long non-coding RNA and its association with tumor progression and ferroptosis in gastric cancer.
OTULIN orchestrates NCOA4-FTH1 complex to alleviate APAP-induced hepatocyte Ferroptosis.
Cell-Free Fat Extract for the Treatment of Lumbar Disc Degeneration: A Novel Approach Using Adipose-Derived Biologic.
Melatonin inhibits salivary gland epithelial cell ferroptosis via the NRF2/HO-1/GPX4 signaling pathway in primary Sjögren's syndrome.
Astilbin Alleviates IL-17-Induced Hyperproliferation and Inflammation in HaCaT Cells via Inhibiting Ferroptosis Through the cGAS-STING Pathway.
Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer.
Tanshinone IIA Promotes Functional Recovery After Spinal Cord Injury by Inhibiting Neuron and Oligodendrocyte Ferroptosis Through the GPX4/ACSL4 Axis.
Perfluorooctane sulfonate induced ferritinophagy via detyrosinated alpha tubulin-TRIM21-HERC2-regulated NCOA4 degradation in hepatocytes.
Mechanistic insights into the role of FAT10 in modulating NCOA4-mediated ferroptosis in pancreatic acinar cells during acute pancreatitis.
Platelet-Rich Plasma-Derived Exosome-Encapsulated Hydrogels Accelerate Diabetic Wound Healing by Inhibiting Fibroblast Ferroptosis.
Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye.
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.
MiR-370-3p regulate TLR4/SLC7A11/GPX4 to alleviate the progression of glucocorticoids-induced osteonecrosis of the femoral head by promoting osteogenesis and suppressing ferroptosis.
SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation.
1,25-(OH)(2)D(3) improves SD rats high-altitude pulmonary edema by inhibiting ferroptosis and ferritinophagy in alveolar epithelial cells.
Delivery of exogenous miR-19b by Wharton's Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism.
Induction of UBQLN1-mediated PGC1α stability by isoliensinine overcame hypoxia-induced resistance in liver cancer cells.
HAT1/HDAC2 mediated ACSL4 acetylation confers radiosensitivity by inducing ferroptosis in nasopharyngeal carcinoma.
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis.
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis.
Ditan Decoction ameliorates vascular dementia-induced cognitive dysfunction through anti-ferroptosis via the HIF1α pathway: Integrating network pharmacology and experimental validation.
A decrease in Flavonifractor plautii and its product, phytosphingosine, predisposes individuals with phlegm-dampness constitution to metabolic disorders.
Nrf2 ameliorates defective autophagic processes and thereby inhibits ferroptosis in acute pancreatitis by suppressing Beclin1-Slc7a11 complex formation.
A Deferoxamine-Loaded Microneedle Patch Enhances Healing of Radiation-Induced Skin Injury: Potential Involvement of Ferroptosis.
Silencing of FZD7 Inhibits Endometriotic Cell Viability, Migration, and Angiogenesis by Promoting Ferroptosis.
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Quercetin-loaded exosomes delivery system prevents myopia progression by targeting endoplasmic reticulum stress and ferroptosis in scleral fibroblasts.
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
Ochratoxin A-induced mitochondrial pathway apoptosis and ferroptosis by promoting glycolysis.
Nutrient deficiency-induced downregulation of SNX1 inhibits ferroptosis through PPARs-ACSL1/4 axis in colorectal cancer.
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
MiR214-3p Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis.
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species.
Network pharmacology analysis reveals that coumestrol targets ZYX to inhibit ferroptosis and alleviate acute pancreatitis.
Chondrocyte-targeted α-Solanine through HIF-1α regulating glycolysis to reduce the ferroptosis of chondrocyte in osteoarthritis.
Quercetin, as a Nutritional Supplement, Protects against Iron Overload-Induced Testicular Dysfunction via Inhibiting Ferroptosis.
Oxidized Albumin Induces Renal Tubular Cell Death and Promotes the Progression of Renal Diseases Through Ferroptosis.
A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.
The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease.
Ambient fine particulate matter induces cardiac fibrosis through triggering ferroptosis by heme degradation induced-iron overload.
MGST1 Inhibits Sevoflurane-Induced Ferroptosis and Activates the Wnt Pathway in HT22 Cells.
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Lutein attenuates rhabdomyolysis-induced acute kidney injury by inhibiting ACSL4-mediated ferroptosis.
Apatinib combined with paclitaxel suppresses synergistically TNBC progression through enhancing ferroptosis susceptibility regulated SLC7A11/GPX4/ACSL4 axis.
Functionalized Biomimetic Nanoparticles Targeting the IL-10/IL-10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis.
Targeting myeloid differentiation protein 2 ameliorates rheumatoid arthritis by inhibiting inflammation and ferroptosis via MAPK and NF-κB signaling pathways.
The deubiquitinase USP24 suppresses ferroptosis in triple-negative breast cancer by stabilizing DHODH protein.
Protocatechuic acid suppresses ferroptosis to protect against hypoxic-ischemic encephalopathy by targeting the HIF-1α/VEGFA axis.
Capsaicin Inhibits Ferroptosis through Facilitating SYVN1-Mediated Ubiquitination and Degradation of ACSL4.
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Metal phenolic networks-driven bufalin homodimeric prodrug nano-coassemblies for ferroptosis-augmented tumor therapy.
Microglial exosome TREM2 ameliorates ferroptosis and neuroinflammation in alzheimer's disease by activating the Wnt/β-catenin signaling.
MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway.
TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4.
Humanin reduces nucleus pulposus cells ferroptosis to alleviate intervertebral disc degeneration: An in vitro and in vivo study.
ACSL4 accelerates osteosarcoma progression via modulating TGF-β/Smad2 signaling pathway.
Quercetin inhibits hydrogen peroxide-induced cleavage of heat shock protein 90 to prevent glutathione peroxidase 4 degradation via chaperone-mediated autophagy.
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Melanin-Deferoxamine Nanoparticles Targeting Ferroptosis Mitigate Acute Kidney Injury via RONS Scavenging and Iron Ion Chelation.
Ethyl acetate fraction of Thesium chinense Turcz. alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis mediated by activating Nrf2/SLC7A11/GPX4 axis.
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
Dihydromyricetin ameliorates neurotoxicity induced by high glucose through restraining ferroptosis by inhibiting JNK-inflammation pathway in HT22 cells.
Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis.
Comprehensive Pan-Cancer Analysis and Functional Studies Reveal SLC2A6 as a Ferroptosis Modulator in Hepatocellular carcinoma.
Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice.
Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc(-)/GSH/GPX4 axis.
Blockade of TIPE2-Mediated Ferroptosis of Myeloid-Derived Suppressor Cells Achieves the Full Potential of Combinatory Ferroptosis and Anti-PD-L1 Cancer Immunotherapy.
METTL3 inhibition promotes radiosensitivity in hepatocellular carcinoma through regulation of SLC7A11 expression.
A pH responsive nanocomposite for combination sonodynamic-immunotherapy with ferroptosis and calcium ion overload via SLC7A11/ACSL4/LPCAT3 pathway.
Activation of PAR1 contributes to ferroptosis of Schwann cells and inhibits regeneration of myelin sheath after sciatic nerve crush injury in rats via Hippo-YAP/ACSL4 pathway.
Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO-1 Pathways.
Sodium pump subunit NKAα1 protects against diabetic endothelial dysfunction by inhibiting ferroptosis through the autophagy-lysosome degradation of ACSL4.
ACSL4 promotes the formation of the proliferative subtype in hepatoblastoma.
Mitophagy and immune cell interaction: insights into pathogenesis and potential targets for necrotizing enterocolitis.
Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation.
Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice.
Metformin Induces Apoptosis and Ferroptosis of Ovarian Cancer Cells Under Energy Stress Conditions.
Astaxanthin Prevents Glucocorticoid-Induced Femoral Head Osteonecrosis by Targeting Ferroptosis through the JAK2/STAT3 Signaling Pathway.
Lactate-Fueled Theranostic Nanoplatforms for Enhanced MRI-Guided Ferroptosis Synergistic with Immunotherapy of Hepatocellular Carcinoma.
A novel defined risk signature of ferroptosis-related lncRNAs for predicting prognosis, immune infiltration, and chemotherapy response in multiple myeloma.
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis.
The extract from Quzhou Aurantii Fructus attenuates cough variant asthma through inhibiting the TRPV1/Ca(2+)/NFAT/TSLP pathway and ferroptosis via TRPV1 mediation in ovalbumin-induced mice.
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
Silencing of APEX1 triggers ferroptosis in clear cell renal cell carcinoma via APP-mediated activation of p53/xCT signaling.
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Membrane-Associated RING-CH-Type Finger 6 Protects against Hypertension-Induced Cardiac Remodeling by Suppressing Cardiomyocyte Ferroptosis Through the Degradation of ACSL4.
EUK nanozyme-loaded PL&GA coacervate droplets attenuate ulcerative colitis through restoring gut homeostasis and restricting intestinal cell ferroptosis.
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
SIRT1 inhibits ferroptosis of granulosa cells in polycystic ovarian syndrome.
Oridonin mitigates bacterial pneumonia by regulating mitochondrial integrity and ferroptosis via targeting KEAP1/NRF2 signaling.
PFGA12 ameliorates Hypoxic-Ischemic brain injury by directly regulating PRDX1 and inhibiting ferroptosis.
Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate.
Lycium barbarum alleviates oxidative stress-induced ferroptosis and enhances mitophagy in intervertebral disc degeneration.
Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2-Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction.
Investigating Nickel-Induced Neurotoxicity: Associations with Gut Microbiota Dysbiosis and Ferroptosis.
Nicotinamide Mononucleotide Alleviates the Development of Fibrotic Cataract by Modulating the Nrf2/FPN1 Signaling Pathway.
TCF3 activates super-enhancer-driven TRIB2 overexpression to suppress ferroptosis and promote hepatoblastoma proliferation.
GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma.
Cold Exposure Exacerbates Allergic Airway Inflammation via Ferroptosis: Evidence from a Murine Model.
Senescence-Primed Ferroptosis Enabled by a Metal-Organic Framework Nanoplatform for Enhanced Cancer Therapy.
Multi-cohort analysis and experimental study on the function of squalene epoxidase as a ferroptosis inhibitor in HCC.
HPDA-based tubule-targeting nanoplatform alleviates oxidative stress and ferroptosis for the reversal of renal interstitial fibrosis.
Therapeutic targeting SPI1 in combination with erastin promotes ferroptosis in ccRCC.
Melanoma MHC-I-membrane-encapsulated Cu@ferrihydrite induces ferroptosis/cuproptosis and systematic immunity against tumor.
Salidroside alleviates senile osteoporosis in SAMP8 mice by inhibiting the ferroptosis of bone marrow stromal cells via PI3K/AKT/mTOR signaling pathway.
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Curcumin derivatives as ferroptosis inducers: design, synthesis and anti breast cancer activity evaluation.
Anticancer activity of Momordica charantia-derived extracellular vesicle-like particle against cervical cancer.
Glutathione peroxidase 7 knockdown inhibits growth, invasion, and migration while enhancing oxidative stress and ferroptosis in osteosarcoma cells.
Lactoferrin prevents heat stroke-induced intestinal barrier damage by reducing ferroptosis via regulating MAPK signaling pathway: In vitro and in vivo studies.
Excessive ultra-processed foods exposure aggravates ulcerative colitis via macrophage ferroptosis.
IGF2BP1 exacerbates neuroinflammation and cerebral ischemia/reperfusion injury by regulating neuronal ferroptosis and microglial polarization.
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
Inhibition of ferroptosis in inflammatory macrophages alleviates intestinal injury in neonatal necrotizing enterocolitis.
Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.
BAOXIN granules reverse ferroptosis through the solute carrier family 7 member -glutathione-glutathione peroxidase 4 axis in ischemia-induced heart failure in rats.
GATA3 promotes ferroptosis resistance by repressing integrin β1 signaling.
A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma.
Qige San regulates paclitaxel resistance in esophageal cancer by targeting ferroptosis.
Synergistic inhibition of TNBC by USP33 and TAP63 through autophagy and ferroptosis activation.
The Capability to Undergo ACSL4-Mediated Ferroptosis Is Acquired During Brown-like Adipogenesis and Affected by Hypoxia.
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
Role of ferroptosis mediated by abnormal membrane structure in DEHP-induced reproductive injury.
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells.
Prepubertal Exposure to Tris(2-chloroethyl) Phosphate Disrupts Blood-Testis Barrier Integrity via Ferritinophagy-Mediated Ferroptosis.
Impact of diabetes and metformin on cuproptosis and ferroptosis in breast cancer patients: an immunohistochemical analysis.
LncRNA FTX promotes colorectal cancer radioresistance through disturbing redox balance and inhibiting ferroptosis via miR-625-5p/SCL7A11 axis.
Synergistic Antioxidant and Anti-Ferroptosis Therapy via BPNS-Encapsulated Thermoresponsive Chitosan Hydrogel for Spinal Cord Injury Regeneration.
Cytolethal distending toxin from Glaesserella parasuis induces ferroptosis in porcine alveolar macrophages and mice.
Mechanism and molecular targets of Euphorbia fischeriana Steud root extract in hepatocellular carcinoma.
Bio-barrier-adaptable biomimetic nanomedicines combined with ultrasound for enhanced cancer therapy.
Lactiplantibacillus plantarum -derived extracellular vesicles alleviate acute lung injury by inhibiting ferroptosis of macrophages.
Transcription factor FOS promotes ferroptosis and inflammation in S. aureus- infected osteomyelitis via EIF5A.
Emodin alleviates the damage to lens epithelial cells in diabetic cataract by repressing the p53-mediated ferroptosis pathway.
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
A Nutrient-Deficient Microenvironment Facilitates Ferroptosis Resistance via the FAM60A-PPAR Axis in Pancreatic Ductal Adenocarcinoma.
Atorvastatin Attenuates Endothelial Cell Injury in Atherosclerosis Through Inhibiting ACSL4-Mediated Ferroptosis.
MAPK1 Mediates MAM Disruption and Mitochondrial Dysfunction in Diabetic Kidney Disease via the PACS-2-Dependent Mechanism.
Cynaroside: a potential therapeutic agent targeting arachidonate 15-lipoxygenase to mitigate cerebral ischemia/reperfusion injury.
GSTT1/GSTM1 deficiency aggravated cisplatin-induced acute kidney injury via ROS-triggered ferroptosis.
LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway.
Kidney tea [Orthosiphon aristatus (Blume) Miq.] improves diabetic nephropathy via regulating gut microbiota and ferroptosis.
Surufatinib combined with photodynamic therapy induces ferroptosis to inhibit cholangiocarcinoma in vitro and in tumor models.
Quercetin alleviates PM(2.5)-induced chronic lung injury in mice by targeting ferroptosis.
The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation.
Urolithin A alleviates cell senescence by inhibiting ferroptosis and enhances corneal epithelial wound healing.
ACSL4 upregulates IFI44 and IFI44L expression and promotes the proliferation and invasiveness of head and neck squamous cell carcinoma cells.
Reactive Oxygen Species-Scavenging Mesoporous Poly(tannic acid) Nanospheres Alleviate Acute Kidney Injury by Inhibiting Ferroptosis.
METTL16-SENP3-LTF axis confers ferroptosis resistance and facilitates tumorigenesis in hepatocellular carcinoma.
Phosphatase LHPP confers prostate cancer ferroptosis activation by modulating the AKT-SKP2-ACSL4 pathway.
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice.
Unveiling the role of RhoA and ferroptosis in vascular permeability: Implications for osteoarthritis.
Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis.
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
A respiratory Streptococcus strain inhibits Acinetobacter baumannii from causing inflammatory damage through ferroptosis.
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
Overexpression of miR-451a Aggravates Renal Ischemia-Reperfusion Injury by Targeting KLF1-ACSL4 to Promote Ferroptosis.
Lysosomal iron accumulation and subsequent lysosomes-mitochondria iron transmission mediate PFOS-induced hepatocyte ferroptosis.
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Unveiling the crucial role of ferroptosis in host resistance to streptococcus agalactiae infection.
Sodium citrate targeting Ca(2+)/CAMKK2 pathway exhibits anti-tumor activity through inducing apoptosis and ferroptosis in ovarian cancer.
Manganese drives ferroptosis of cancer cells via YAP/TAZ phase separation activated ACSL4 in OSCC.
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice.
Lithospermic acid improves liver fibrosis through Piezo1-mediated oxidative stress and inflammation.
IL6 Derived from Macrophages under Intermittent Hypoxia Exacerbates NAFLD by Promoting Ferroptosis via MARCH3-Led Ubiquitylation of GPX4.
Development of oxidative stress- and ferroptosis-related prognostic signature in gastric cancer and identification of CDH19 as a novel biomarker.
Iberverin Downregulates GPX4 and SLC7A11 to Induce Ferroptotic Cell Death in Hepatocellular Carcinoma Cells.
TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo study.
Melatonin Attenuates Ferritinophagy/Ferroptosis by Acting on Autophagy in the Liver of an Autistic Mouse Model BTBR T(+)Itpr3(tf)/J.
Carthamin yellow alleviates dextran sodium sulfate-induced ulcerative colitis by repairing the intestinal barrier and activating the Nrf2/GPX4 axis.
LncRNA MALAT1 promotes Erastin-induced ferroptosis in the HBV-infected diffuse large B-cell lymphoma.
Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF.
The effect of tau K677 lactylation on ferritinophagy and ferroptosis in Alzheimer's disease.
Epithelial Piezo1 deletion ameliorates intestinal barrier damage by regulating ferroptosis in ulcerative colitis.
Hippocampal Pyk2 regulates specific social skills: Implications for schizophrenia.
A combined nanotherapeutic approach targeting farnesoid X receptor, ferroptosis, and fibrosis for nonalcoholic steatohepatitis treatment.
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
FTH1 overexpression using a dCasRx translation enhancement system protects the kidney from calcium oxalate crystal-induced injury.
MiR-31-5p alleviates septic cardiomyopathy by targeting BAP1 to inhibit SLC7A11 deubiquitination and ferroptosis.
Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis.
ABI3BP promotes renal aging through Klotho-mediated ferroptosis.
[Inhibition of Lung Squamous Cancer Target HMGCS1 Promotes Cellular Ferroptosis].
Metabolomics analysis revealed the neuroprotective role of 2-phosphoglyceric acid in hypoxic-ischemic brain damage through GPX4/ACSL4 axis regulation.
Evaluating the efficacy and mechanisms of Hua-Zhuo-Ning-Fu-Decoction on psoriasis using integrated bioinformatics analysis and metabolomics.
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Allogeneic platelet-rich plasma inhibits ferroptosis in promoting wound repair of type 2 diabetic ulcers.
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Ozone-mediated cerebral protection: Unraveling the mechanism through ferroptosis and the NRF2/SLC7A11/GPX4 signaling pathway.
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx.
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
The TF/Nrf2/GSTP1 pathway is involved in stress-induced hepatocellular injury through ferroptosis.
ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription.
Experimental verification about treatment of Bu-Shen-Yi-Jing-Fang in Alzheimer's disease by the analysis of the feasible signaling pathway of network pharmacology.
Phosphorylated FOXQ1, a novel substrate of JNK1, inhibits sorafenib-induced ferroptosis by activating ETHE1 in hepatocellular carcinoma.
MARK4 aggravates cardiac dysfunction in mice with STZ-induced diabetic cardiomyopathy by regulating ACSL4-mediated myocardial lipid metabolism.
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron.
Ciprofloxacin is a novel anti-ferroptotic antibiotic.
Metabolomics reveals that ferroptosis participates in bisphenol A-induced testicular injury.
ACLS4 could be a potential therapeutic target for severe acute pancreatitis.
ERRFI1 exacerbates hepatic ischemia reperfusion injury by promoting hepatocyte apoptosis and ferroptosis in a GRB2-dependent manner.
Lipoxin A(4) ameliorates knee osteoarthritis progression in rats by antagonizing ferroptosis through activation of the ESR2/LPAR3/Nrf2 axis in synovial fibroblast-like synoviocytes.
DDX39B protects against sorafenib-induced ferroptosis by facilitating the splicing and cytoplasmic export of GPX4 pre-mRNA in hepatocellular carcinoma.
TaoHe ChengQi decoction ameliorates sepsis-induced cardiac dysfunction through anti-ferroptosis via the Nrf2 pathway.
Intermittent hypoxia exacerbates metabolic dysfunction-associated fatty liver disease by aggravating hepatic copper deficiency-induced ferroptosis.
Ferroptosis: First evidence in premature duck ovary induced by polyvinyl chloride microplastics.
KLF6 silencing attenuates MCAO-induced brain injury and cognitive dysfunction via targeting ferroptosis and activating the Nrf2/HO-1 pathway.
Cadmium Induces Kidney Iron Deficiency and Chronic Kidney Injury by Interfering with the Iron Metabolism in Rats.
Inhibition of cisplatin-induced Acsl4-mediated ferroptosis alleviated ovarian injury.
FGF10 protects against LPS-induced epithelial barrier injury and inflammation by inhibiting SIRT1-ferroptosis pathway in acute lung injury in mice.
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
Quercetin attenuates cerebral ischemic injury by inhibiting ferroptosis via Nrf2/HO-1 signaling pathway.
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
7-Dehydrocholesterol dictates ferroptosis sensitivity.
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Se-(Methyl)-selenocysteine ameliorates blood-brain barrier disruption of focal cerebral ischemia mice via ferroptosis inhibition and tight junction upregulation in an Akt/GSK3β-dependent manner.
Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.
WWP2 protects against sepsis-induced cardiac injury through inhibiting cardiomyocyte ferroptosis.
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells.
Sensitization of cancer cells to ferroptosis coincident with cell cycle arrest.
High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.
PRKN-mediated the ubiquitination of IQGAP3 regulates cell growth, metastasis and ferroptosis in early-onset colorectal cancer.
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
The m(6)A modification of ACSL4 mRNA sensitized esophageal squamous cell carcinoma to irradiation via accelerating ferroptosis.
Sirt6 overexpression relieves ferroptosis and delays the progression of diabetic nephropathy via Nrf2/GPX4 pathway.
Mild therapeutic hypothermic protection activates the PI3K/AKT signaling pathway to inhibit TRPM7 and suppress ferroptosis induced by myocardial ischemia‑reperfusion injury.
Comprehensive Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Data Unveils Sevoflurane-Induced Neurotoxicity Through SLC7A11-Associated Ferroptosis.
Naringenin alleviates intestinal ischemia/reperfusion injury by inhibiting ferroptosis via targeting YAP/STAT3 signaling axis.
Self-Produced O(2) CNs-Based Nanocarriers of DNA Hydrophobization Strategy Triggers Photodynamic and Mitochondrial-Derived Ferroptosis for Hepatocellular Carcinoma Combined Treatment.
Sirtuin1 Suppresses Calcium Oxalate Nephropathy via Inhibition of Renal Proximal Tubular Cell Ferroptosis Through PGC-1α-mediated Transcriptional Coactivation.
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria.
BMAL1 alleviates sepsis-induced AKI by inhibiting ferroptosis.
MCM4 potentiates evasion of hepatocellular carcinoma from sorafenib-induced ferroptosis through Nrf2 signaling pathway.
Screening of orthopedic medicines identifies raloxifene hydrochloride as a novel ferroptosis inhibitor for spinal cord injury therapy.
Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt3.
ASIC1a regulates ferroptosis in hepatic stellate cells via the Hippo/Yap-1 pathway in liver fibrosis.
ACSL4-mediated ZIP7-VDAC3 interaction regulates endoplasmic reticulum-mitochondria iron transfer in hepatocytes under PFOS exposure.
Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis.
Integrated network pharmacology and transcriptomics to explore the mechanism of compound Dihuang granule (CDG) protects dopaminergic neurons by regulating the Nrf2/HMOX1 pathway in the 6-OHDA/MPP(+)-induced model of Parkinson's disease.
High glucose elevates intracellular calcium level and induces ferroptosis in glomerular endothelial cells through the miR-223-3p/ITPR3 pathway.
Ion channel Piezo1 induces ferroptosis of trabecular meshwork cells: a novel observation in the pathogenesis in primary open angle glaucoma.
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro.
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
GOLPH3 inhibits erastin-induced ferroptosis in colorectal cancer cells.
Preventive effects of lactoferrin on acute alcohol-induced liver injury via iron chelation and regulation of iron metabolism.
Identification of ferroptosis-related key genes associated with immune infiltration in sepsis by bioinformatics analysis and in vivo validation.
Sterigmatocystin declines mouse oocyte quality by inducing ferroptosis and asymmetric division defects.
APOL6 predicts immunotherapy efficacy of bladder cancer by ferroptosis.
Screening of NSAIDs library identifies Tinoridine as a novel ferroptosis inhibitor for potential intervertebral disc degeneration therapy.
Natural Product Auraptene Targets SLC7A11 for Degradation and Induces Hepatocellular Carcinoma Ferroptosis.
Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis.
Tetramethylpyrazine alleviates ferroptosis and promotes functional recovery in spinal cord injury by regulating GPX4/ACSL4.
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Sodium octanoate alleviates cardiac and cerebral injury after traumatic cardiac arrest in a porcine model.
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53-P21/Nrf2 activation in a HuR-dependent m6A manner.
Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis.
GPX4-mediated bone ferroptosis under mechanical stress decreased bone formation via the YAP-TEAD signalling pathway.
Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1.
Non-targeted metabolomics strategy reveals the role of Geng-Nian-Shu in regulating ferroptosis in perimenopausal syndrome.
CHAC1 exacerbates LPS-induced ferroptosis and apoptosis in HK-2 cells by promoting oxidative stress.
Detection of Ferroptosis by Immunohistochemistry and Immunofluorescence.
Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice.
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Matrine Alleviates Sepsis-Induced Myocardial Injury by Inhibiting Ferroptosis and Apoptosis.
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.
STING/ACSL4 axis-dependent ferroptosis and inflammation promote hypertension-associated chronic kidney disease.
Insight into the effect of a heavy metal mixture on neurological damage in rats through combined serum metabolomic and brain proteomic analyses.
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
E3 ubiquitin ligase Siah1 aggravates NAFLD through Scp2 ubiquitination.
The BRD4-SRPK2-SRSF2 signal modulates the splicing efficiency of ACSL3 pre-mRNA and influences erastin-induced ferroptosis in osteosarcoma cells.
PDPN(+) CAFs facilitate the motility of OSCC cells by inhibiting ferroptosis via transferring exosomal lncRNA FTX.
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.
ACSL4 serves as a novel prognostic biomarker correlated with immune infiltration in Cholangiocarcinoma.
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
ZNF8-miR-552-5p Axis Modulates ACSL4-Mediated Ferroptosis in Hepatocellular Carcinoma.
1,25-Dihydroxyvitamin D3 alleviates hyperandrogen-induced ferroptosis in KGN cells.
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes.
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway.
SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis.
Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.
A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2.
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis.
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
3,6-Epidioxy-1,10-bisaboladiene induces ferroptosis-like cell death through lipid peroxidation.
Xanthohumol attenuates renal ischemia/reperfusion injury by inhibiting ferroptosis.
Inhibition of CARM1-Mediated Methylation of ACSL4 Promotes Ferroptosis in Colorectal Cancer.
Characteristics and time points to inhibit ferroptosis in human osteoarthritis.
lnc-HC ameliorates steatosis by promoting miR-130b-3p biogenesis and the assembly of an RNA-induced silencing complex.
Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer.
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis.
Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway.
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer.
Cyclosporine A-loaded apoferritin alleviates myocardial ischemia-reperfusion injury by simultaneously blocking ferroptosis and apoptosis of cardiomyocytes.
The Effects of Alda-1 Treatment on Renal and Intestinal Injuries After Cardiopulmonary Resuscitation in Pigs.
Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage.
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Zinc Oxide Nanoparticle Inhibits Tumorigenesis of Renal Cell Carcinoma by Modulating Lipid Metabolism Targeting miR-454-3p to Repressing Metabolism Enzyme ACSL4.
Probiotic Saccharomyces boulardii attenuates cardiopulmonary bypass-induced acute lung injury by inhibiting ferroptosis.
Itraconazole Inhibits the Growth of Cutaneous Squamous Cell Carcinoma by Targeting HMGCS1/ACSL4 Axis.
NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells.
Context-dependent regulation of ferroptosis sensitivity.
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
α-Syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson's disease.
Amentoflavone promotes ferroptosis by regulating reactive oxygen species (ROS) /5'AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) to inhibit the malignant progression of endometrial carcinoma cells.
Plasma-activated medium induces ferroptosis by depleting FSP1 in human lung cancer cells.
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats.
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Inhibition of the PIN1-NRF2/GPX4 axis imparts sensitivity to cisplatin in cervical cancer cells.
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Ferroptosis is involved in PGPS-induced otitis media in C57BL/6 mice.
Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance.
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Stearoyl-CoA Desaturase 1 Potentiates Hypoxic plus Nutrient-Deprived Pancreatic Cancer Cell Ferroptosis Resistance.
Mesenchymal Stem Cells Alleviate Post-resuscitation Cardiac and Cerebral Injuries by Inhibiting Cell Pyroptosis and Ferroptosis in a Swine Model of Cardiac Arrest.
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway.
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Ferrostatin-1 alleviated TNBS induced colitis via the inhibition of ferroptosis.
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.
Nuclear receptor coactivator 4-mediated ferritinophagy drives proliferation of dental pulp stem cells in hypoxia.
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
LncRNA NEAT1 promotes docetaxel resistance in prostate cancer by regulating ACSL4 via sponging miR-34a-5p and miR-204-5p.
Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases.
The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis.
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation.
The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells.
Quantitative proteomics by SWATH-MS reveals sophisticated metabolic reprogramming in hepatocellular carcinoma tissues.
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
Tumor-suppressive functions of long-chain acyl-CoA synthetase 4 in gastric cancer.
Quantitative proteomic analysis identifies new effectors of FOXM1 involved in breast cancer cell migration.
Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells.
Involvement of cholesterol in hepatitis B virus X protein-induced abnormal lipid metabolism of hepatoma cells via up-regulating miR-205-targeted ACSL4.
Zhang L, Luo F, Chai Y, Sun L, Wang X, Yin L, Luo C
PloS one 2026;21(2):e0342335
PloS one 2026;21(2):e0342335
Chondroitin sulfate alleviates osteoarthritis by upregulating HSPA8 to inhibit chondrocyte ferroptosis.
Jiang J, Xu Y, Dai T, Chen J, Li S, Meng Q
PloS one 2026;21(2):e0342242
PloS one 2026;21(2):e0342242
Monitoring early micro-oxidation under refrigeration: iron and oxidative markers predict quality loss in grass carp.
Xiong X, Feng R, Zhang H, Ding N, Zhuang S, Tan Y, Ma H, Hong H, Luo Y
Current research in food science 2026;12:101307
Current research in food science 2026;12:101307
Multifunctional selenium nanoplatforms for synergistic ferroptosis inhibition and immune microenvironment remodeling in oral mucositis.
Ouyang Q, Gao R, Li S, Liang J, Li P, Zhou W
Biomaterials 2026 Sep;332:124147
Biomaterials 2026 Sep;332:124147
A novel recombinant peptide, rAnguillin, induces ferroptosis in nasopharyngeal carcinoma by promoting FOXM1 degradation and disrupting the FOXM1-PABPC1L-tryptophan metabolism axis.
Yuan Q, Zhao Y, Zhou F, Zhang Y, Jia X, Yao J, Lv M, Wang J, Lv L
International journal of biological macromolecules 2026 May;361:151988
International journal of biological macromolecules 2026 May;361:151988
NRH attenuates age-related hearing loss by suppressing cochlear ferroptosis and cellular senescence via Sirt3 activation.
Yuan C, Feng C, Ma T, Li S, Liu M, Tang G, Han L, Xing Y, Zhang T
Free radical biology & medicine 2026 May;248:450-468
Free radical biology & medicine 2026 May;248:450-468
NCOA4-mediated ferroptosis drives cGAS-STING-dependent inflammation in radiation dermatitis: Protective modulation by Cu-ATSM.
Li S, Chen L, Fang Z, Shen W, Cai J, Dong B, Lin T, Zhang R, Jin L, Liu C, Wu F, Wu Q, Chen D
Free radical biology & medicine 2026 May;248:401-412
Free radical biology & medicine 2026 May;248:401-412
Curcumin augments mitophagy via Nrf2-PINK1-mediated, Parkin-dependent ubiquitination to suppress ferroptosis in post-cardiac arrest brain injury.
Li Z, Xu W, Ren S, Zheng Q, Xing J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158035
Huzhang-Xiangbaji compounds enhance the repair of meniscal cartilage by inhibiting ferroptosis and inflammatory microenvironment.
Li J, Zhou J, Zhang G, Ding N, Kuang Z, Wang J, Liu N, Jia G, Jiang M, Wu S, Yang J, Ding X, Lei Z, Nie Y, Zhang Y, Li Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158008
g-C(3)N(4) Nanosheets as a Ferroptosis-Targeted Nanoprobe: Mitigating Iron Overload and Restoring Male Fertility via Nrf2 Pathway Activation.
Wang L, Yang F, Ye Z, Lu R, Wei J, Liu M, Chen G, Ding W
Molecular pharmaceutics 2026 May 4;23(5):2857-2870
Molecular pharmaceutics 2026 May 4;23(5):2857-2870
Yitangkang decoction in the treatment of glomerular filtration barrier damage through AMPKα1/ZDHHC8/SLC7A11/GPX4 and TGF-β/Smad signaling pathways: A multi-omics analysis.
Yu J, Zhang H, Wu Y, Di Z, Shi Y, Fan X, Dong B, Dai J, Wang Z, Chen Y, Liu W, Zhang W
Journal of ethnopharmacology 2026 May 23;363:121410
Journal of ethnopharmacology 2026 May 23;363:121410
Qiangji Jianli Decoction attenuates skeletal muscle injury in rats with experimental autoimmune myasthenia gravis via the GRP78/IRE1α/GPX4 signaling pathway.
Cai X, Fan S, Yang P, Zhao L, Jiao Y, Liang J, Chen T, Huang T, Song Y
Journal of ethnopharmacology 2026 May 10;362:121368
Journal of ethnopharmacology 2026 May 10;362:121368
Naringenin inhibits Ferroptosis and ameliorates interstitial cystitis with metabolic syndrome by activating the Nrf2/NQO-1 pathway.
Zhao J, Ju C, Shao C, Sun Y, Yang T, Liu J, Wu D, Li H, Jia R, Zhou L, Zhao F
International immunopharmacology 2026 May 1;176:116485
International immunopharmacology 2026 May 1;176:116485
EGR1 promotes ferroptosis in endometriosis through transcriptional activation of HMOX1.
Yang F, Liu D, Hu L, Tan H, Wei Y, Yang R, Huang B, Zou Q, Wu Q, He Y, Mai H, Lan X, Yan Y, Huang Z, Huang X, Fu Z, Deng Z, Huang Q, Yao S, Liang Y
Molecular and cellular endocrinology 2026 Mar;613:112721
Molecular and cellular endocrinology 2026 Mar;613:112721
Andrographolide blocked the progression of endometriosis by promoting ferroptosis via inhibiting anabolism of serine.
Ye W, Zhang N, Li J, Wang F, Liu X, Zhang R, Chen H, Cheng L, Wei Z, Zhu F
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(6):7935-7952
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar;399(6):7935-7952
AARS1-mediated lactylation of H3K18 and STAT1 promotes ferroptosis in diabetic nephropathy.
Hong J, Xu H, Yu L, Yu Z, Chen X, Meng Z, Zhu J, Li J, Zhu M
Cell death and differentiation 2026 Mar;33(3):589-604
Cell death and differentiation 2026 Mar;33(3):589-604
Rhein-Emodin Combination Activates UQCRC1 to Attenuate MPP(+)-Induced Ferroptosis in Dopaminergic Neurons.
Yusun A, Wan H, Li S, Liu Y, Chen H, Sun M, Ding X, Zhang C
Chemistry & biodiversity 2026 Mar;23(3):e02053
Chemistry & biodiversity 2026 Mar;23(3):e02053
M2 macrophage-derived exosome nanoplatform for targeted H(2)S delivery to alleviate hepatic ischemia-reperfusion injury via synergistic anti-oxidative, anti-inflammatory, and anti-ferroptotic effects.
Zuo T, Shi C, Li J, Li D, Luo X, Xu M, Su M, Lu H, Zhang Y, Hu X, Zhou Q, Shubhra QTH, He X, Cai X
Acta biomaterialia 2026 Mar;212:593-612
Acta biomaterialia 2026 Mar;212:593-612
RBM3-mediated m6A modification of KLF6 promotes ACSL4-driven ferroptosis in ulcerative colitis.
Leng X, Wang A, Wu Y, Wang H, Chen B, Long G, Yu P
Immunology and cell biology 2026 Mar;104(3):249-264
Immunology and cell biology 2026 Mar;104(3):249-264
Sertad1 exacerbates cardiomyocytes ferroptosis in sepsis-induced myocardial injury by inhibiting HIPK2.
Hu C, Miao J, Zhao Q, Chen L
Molecular biology reports 2026 Mar 7;53(1)
Molecular biology reports 2026 Mar 7;53(1)
Boron Triggers Hepatic Ferroptosis: Unveiling the Dual-Pathogenic Nexus of Oxidative Stress and SLC7A11/GPX4 Dysregulation.
He T, Li Y, Huang J, Su W, Liu S, Quan J, Zhong G, Liu Z, Shi D, Yu W
Animals : an open access journal from MDPI 2026 Mar 6;16(5)
Animals : an open access journal from MDPI 2026 Mar 6;16(5)
Targeting SLC6A8 suppresses tumor growth and enhances ferroptosis in hepatocellular carcinoma.
Bao W, Yu Y, Yu G, Chen J, Li Y, Hai Y
Journal of cancer research and clinical oncology 2026 Mar 5;152(3)
Journal of cancer research and clinical oncology 2026 Mar 5;152(3)
TIMP3 Suppresses Oxidative Stress and Ferroptosis of Lens Epithelial Cells in Cataract Through Regulating the Keap1/Nrf2 Pathway.
Duan Z, Zhuo B, Ma D, Hua Z, Han X, Cai L, Yang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71688
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2026 Mar 31;40(6):e71688
Systemic Oxidative Stress and Oxidized Albumin Mediate the Pathogenic Kidney-to-Gut Crosstalk by Disrupting Intestinal Barrier Integrity.
Cheng J, Sui Y, Wang X, Xu Y, Jiang R, Zhang Y, Shi Z, Suda M, Fan J, Yao J
Biomolecules 2026 Mar 18;16(3)
Biomolecules 2026 Mar 18;16(3)
A core-shell microneedle platform for the spatiotemporal codelivery of dual-agent therapeutics precisely orchestrates diabetic wound healing.
Zhan Y, Zhang Z, Zhang Z, Lin M, Liu H, Abulimiti D, Aihemaiti S, Kan Y, Tan J, Chen X, Tao S
Journal of nanobiotechnology 2026 Mar 17;24(1)
Journal of nanobiotechnology 2026 Mar 17;24(1)
Microneedle patches deliver targeted GLP-1RAs-loaded nanoparticles for the treatment of rheumatoid arthritis.
Zhang H, Liu Y, Zhang S, Wang Z, Zhang X, Zhang Y, Zhang J, Liang S, Li C, Su M, Tian Z, Luo L
Journal of nanobiotechnology 2026 Mar 16;24(1)
Journal of nanobiotechnology 2026 Mar 16;24(1)
LCN2 aggravates sepsis-induced ALI by inhibiting MUC1 to activate ER-stress-autophagy induced ferroptosis via lactate/MCT1/AMPK/mTOR axis.
Chen SX, Qi X, Zheng XT, Bi ZM, Zhang Y, Wang YM
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
Apoptosis : an international journal on programmed cell death 2026 Mar 15;31(3)
CXCL12 Promotes Peripheral Nerve Injury Repair by Inhibiting the Ferroptosis-Inflammation Axis via the ERK/Nrf2 Pathway.
Yuan Y, Jiang Y, Du S, Yuan G, Yang Z, Wang P
Inflammation 2026 Mar 12;49(1)
Inflammation 2026 Mar 12;49(1)
ROS-Responsive Prodrug Containing Dihydroartemisinin and Cinnamaldehyde for the Potential Treatment of Nonalcoholic Steatohepatitis.
Hao R, Sun Y, Wang C, Wang Y, Li L, Sun H, Chen L
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
ACS applied materials & interfaces 2026 Mar 11;18(9):13384-13397
Cell size modulates ferroptosis susceptibility.
Zatulovskiy E, Murray MB, Zhang S, Dixon SJ, Skotheim JM
bioRxiv : the preprint server for biology 2026 Mar 11;
bioRxiv : the preprint server for biology 2026 Mar 11;
Membrane-translocated SO₂/₃-PRDX3 disrupts cystine uptake and GPX4 activity: A pivotal mechanism of boron-induced renal ferroptosis in broiler.
Li Y, Li Y, Guo M, Tian Y, Wang M, Huang J, Su W, Liu Z, Yu W
Ecotoxicology and environmental safety 2026 Mar 1;312:119969
Ecotoxicology and environmental safety 2026 Mar 1;312:119969
Paeoniflorin mitigates myocardial hypertrophy by regulating mitophagy and ferroptosis mediated by mitochondria-associated AMPK-Parkin-ACSL4 pathway.
Wang Y, Lin S, Liu J, Hu S, Zeng J, Wang M, Li X, He Y, Ren S, Lyu Y, Jia W, Zhao Y, Lin Y
Free radical biology & medicine 2026 Mar 1;245:98-114
Free radical biology & medicine 2026 Mar 1;245:98-114
A spinal USP7-Bach1 positive feedback loop drives NOX4-mediated ferroptosis in neuropathic pain.
Jiao B, Liu S, Zhang K, Zhang W, Cao X, Zhang X, Sun J, Xu H
Redox biology 2026 Jun;93:104153
Redox biology 2026 Jun;93:104153
A mitochondria-targeted nanoantioxidant restores alveolar bone homeostasis in periodontitis by quenching ROS and suppressing the cGAS-STING pathway.
Huang N, Cao L, Xu Y, Pan L, Zheng A, Wang X, Jiang X
Bioactive materials 2026 Jun;60:574-589
Bioactive materials 2026 Jun;60:574-589
Rational design of FAP-targeted sEVs delivered by microneedles for precision treatment of hypertrophic scars via ferroptosis in hypertrophic scar fibroblasts.
Xu Y, Zhang Y, Sun Z, Gong J, Shen Q, Meng H, Liu X, Chen J, Hao Y, Xu Z, Ma K, Ma L, Guo K, Pan X, Fu X, Zhang C
Materials today. Bio 2026 Jun;38:103117
Materials today. Bio 2026 Jun;38:103117
ZDBF2/SIRT6-mediated H3K27 deacetylation inhibits ferroptosis and reduces sensitivity of oral squamous cell carcinoma to cisplatin.
Liu K, Rong L, Shuai Y, Mu R, Ding H, Chen B, Jin L
Pathology, research and practice 2026 Jun;282:156419
Pathology, research and practice 2026 Jun;282:156419
Urinary exosomes aggravate diabetic kidney disease by inducing podocyte ferroptosis via the miR-217/SIRT1/Nrf2 pathway.
Du X, Jiang Y, Guo H, Zhang H, Wang S, Deng H, Huang X, Li X
Journal of cell communication and signaling 2026 Jun;20:e70076
Journal of cell communication and signaling 2026 Jun;20:e70076
Shunaoxin dropping pills alleviate cerebral ischemia-reperfusion injury in MCAO rats associated with ferroptosis inhibition and AKT/Nrf2/HO-1 pathway activation.
Guo Y, Cheng X, Song Y, Li D, Deng H, Qin X, Hao H, Han Y, Xu W, Zhao L, Xu S
Fitoterapia 2026 Jun;191:107245
Fitoterapia 2026 Jun;191:107245
Momordin Ic targets SREBP1 to disrupt lipid homeostasis and trigger synergistic apoptosis-ferroptosis in triple-negative breast cancer.
Cheng Y, Shi YZ, Zheng JY, Liu YB, Chen YT, Bao JX, He XY, Chen JQ, Li Q, Dai XX
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158190
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Jun;155:158190
Copper potentiates PUFA-mediated antitumor activity by activating Lipophagy.
He X, Yang Q, Lin X, Chen Z, Ren K, Yang J, An X, Yang S, Yang L, Xue Q, Chen X, Wang Y, Yu G, Yan D, Chen X
Cellular signalling 2026 Jun;142:112454
Cellular signalling 2026 Jun;142:112454
Therapeutic mechanism of Changyong Decoction in suppressing colorectal cancer progression and inducing ferroptosis via the PIEZO1-PI3K/AKT signaling axis.
Han M, Shi S, Guan Z, Ma W, Wang X, Jiang H, Man S
Tissue & cell 2026 Jun;100:103379
Tissue & cell 2026 Jun;100:103379
Kaempferide alleviates glucocorticoid-induced osteoporosis by targeting ferroptosis through the GSK3β/Nrf-2/GPX4 pathway.
Wu ZH, Han LJ, Zhang JX, Lin YZ, Fang X, Guo YF, Jin C, Guo XS, Chen L
International immunopharmacology 2026 Jun 15;179:116601
International immunopharmacology 2026 Jun 15;179:116601
Synergistic induction of ferroptosis by paclitaxel and sunitinib is mediated through SLC7A11 in lung cancer.
Jin M, Hu J, Zheng A, Wu H, Liu S, Wu C, Liu J, Shen H, Han F
International immunopharmacology 2026 Jun 15;179:116595
International immunopharmacology 2026 Jun 15;179:116595
Microenvironment-educated MSC-EVs loaded injectable smart hydrogel for targeting senescent nucleus pulposus cells and inhibiting ferroptosis against intervertebral disc degeneration.
Wu W, Cheng Z, Shi P, Gao H, Chen X, Wu W, Yu Z, Yang C, Zhang Y
Bioactive materials 2026 Jul;61:555-576
Bioactive materials 2026 Jul;61:555-576
Pyrvinium pamoate inhibits the survival of intracellular Mycobacterium tuberculosis through suppression of macrophage ferroptosis.
Guan Q, Zhou Y, Han JL, Guo F, Li Z, Zhou Y, Zhang XL
Bioorganic chemistry 2026 Jul 5;175:109753
Bioorganic chemistry 2026 Jul 5;175:109753
Sodium Houttuyfonate improves cognitive impairment in mice after chronic sleep deprivation by inhibiting microglial inflammation and ferroptosis.
Li R, Zhu Y, Wei H, Yu M, Xu Y
International immunopharmacology 2026 Jul 1;180:116688
International immunopharmacology 2026 Jul 1;180:116688
Loss of cGAS facilitates angiogenesis in diabetic foot ulcer healing by suppressing the STING/ferroptosis pathway.
Li W, Kang M, Zhang G, Hu H, Qin H
International immunopharmacology 2026 Jul 1;180:116684
International immunopharmacology 2026 Jul 1;180:116684
Identifying cathepsin B as a key regulator of programmed cell death in acute pancreatitis.
Xie X, Jia Y, Wang Z, Zhang H, Lu J, Cao F, Li F
International immunopharmacology 2026 Jul 1;180:116680
International immunopharmacology 2026 Jul 1;180:116680
The CHPT-pSTAT3-SLC7A11 signaling axis controls progression and ferroptosis susceptibility of pancreatic cancer.
Yang J, Liu J, Rong Z, Tan Z, Wang W, Meng Q, Wei M, Hua J, Zhang B, Yu X, Xu J, Liang C
Translational oncology 2026 Jan;63:102624
Translational oncology 2026 Jan;63:102624
The METTL3/IGF2BP1 axis-mediated m6 A modification of TRIM11 mRNA suppresses ferroptosis and accelerates malignant progression in non-small cell lung cancer cells by degrading ACSL4.
Chen H, Wang C, Dai H, Shi J
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(1):665-681
Naunyn-Schmiedeberg's archives of pharmacology 2026 Jan;399(1):665-681
N6-methyladenosine (m(6)A) modification regulates LONP1 to inhibit coxsackievirus B3 replication by suppressing virus-induced ferroptosis.
Wang Q, Wang Y, Liu T, Wang H, Yuan M, Zhang T, Ji Z, Shen H
International journal of biological macromolecules 2026 Jan;335(Pt 1):149287
International journal of biological macromolecules 2026 Jan;335(Pt 1):149287
MC1R contributes to ferroptosis resistance and tumor aggressiveness in colorectal cancer by activating Notch signaling.
Zeng X, Jiang L, Li H, Wang J, He X
Cancer gene therapy 2026 Jan;33(1):26-38
Cancer gene therapy 2026 Jan;33(1):26-38
Resveratrol can inhibit porcine reproductive and respiratory syndrome virus infection in vitro and in vivo by inhibiting PI3K/Akt signaling pathway.
Chen Y, Chen W, Song X, Zhao X, Yang L, Zhao R, Song M, Zhang B, Sun D
Veterinary microbiology 2026 Jan;312:110823
Veterinary microbiology 2026 Jan;312:110823
Eugenol attenuates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the Nrf2/GPX4 pathway.
Sun S, Lu X, Yang S, Liang H, Lyu G, Chen Y, Yu L, Gao Z, Wang J, Xiao P, Jin L, Huang C, Wang X
Free radical biology & medicine 2026 Jan;242:508-520
Free radical biology & medicine 2026 Jan;242:508-520
Unveiling Novel Biomarkers: Ferroptosis and m1A in the Progression of Nanographene-Induced Lung Fibrosis.
Xia J, Wu W, Fan H, Tang X, Li S, Tang K, Hao C, Xu Q, Zhao Y, Yao W
Small (Weinheim an der Bergstrasse, Germany) 2026 Jan;22(5):e08818
Small (Weinheim an der Bergstrasse, Germany) 2026 Jan;22(5):e08818
Integrated proteomic and metabolomic analysis reveals lipid metabolic dysregulation and ferroptosis as potential drivers of placental dysfunction in intrahepatic cholestasis of pregnancy.
Dong R, Wang G, Shi Y, Gao J, Hu W, Zhang T
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159692
Biochimica et biophysica acta. Molecular and cell biology of lipids 2026 Jan;1871(1):159692
Fisetin Ameliorates Vascular Calcification by Regulating HNRNPA1-Mediated Ferroptosis.
Feng Q, He L, He Y, Li X, Xu R, Xu X, Jiang T, He Y
Annals of vascular surgery 2026 Jan;122:76-85
Annals of vascular surgery 2026 Jan;122:76-85
Renal-targeted exosomes inhibiting miR-182-5p for treatment of renal ischemia-reperfusion injury.
Li Z, Sun S, Zhao Z, Guo Y, He Q, Yang M, Zheng J, Li J, Xue W, Ding C
Bioengineering & translational medicine 2026 Jan;11(1):e70081
Bioengineering & translational medicine 2026 Jan;11(1):e70081
Methotrexate-triggered ferroptosis suppresses oral cancer progression by phosphorylated KEAP1-mediated NRF2 degradation to inhibit SLC7A11/GPX4 signaling pathway.
Yu C, Zhang T, Yuan J, Su Y, Zhang H, Xu L, Li X, Cui J, Xu R, Zhou Y, Huang H, Zhou X, Zhou Y, Zhang E
Cancer cell international 2026 Jan 6;26(1):64
Cancer cell international 2026 Jan 6;26(1):64
Cucurbitacin B Inhibits Hepatocellular Carcinoma by Inducing Ferroptosis and Activating the cGAS-STING Pathway.
Zhang H, Chang A, Xu X, Peng H, Zhang K, Yang J, Li W, Wang X, Wang W, Yin X, Qu C, Dong X, Ni J
Current issues in molecular biology 2026 Jan 27;48(2)
Current issues in molecular biology 2026 Jan 27;48(2)
Betaine Inhibits Ferroptosis After Intracerebral Hemorrhage by Activating the Nrf2/HO-1 Pathway.
Chen J, Lu X, Liu S, Hu W, Zhou X, Wang Z
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Antioxidants (Basel, Switzerland) 2026 Jan 21;15(1)
Moscatilin alleviates severe acute pancreatitis by activating the NRF2/HO-1 pathway to inhibit ferroptosis.
Niu L, Yang Z, Zeng Y, Huang Z, Yang T, Liu S, Zhong H, Ye M, Lei S, Gao L, Tan P, Fu W
International immunopharmacology 2026 Jan 15;169:115972
International immunopharmacology 2026 Jan 15;169:115972
SREBP2 confers ferroptosis resistance by targeting GPX4 in colorectal cancer.
Zhong H, Chen R, Chen T, Lin M, Wen S, Zhang M, Liu D, Yu J, Chen J, Yi B, Liang R, Jiang W, Li Z
Apoptosis : an international journal on programmed cell death 2026 Jan 10;31(1):30
Apoptosis : an international journal on programmed cell death 2026 Jan 10;31(1):30
Licochalcone D modulates macrophage ferroptosis via suppression of VPS4A-mediated lipophagy to alleviate MRSA pneumonia.
Zhang H, Liu X, Han Q, Zhang Q, Lv N, Gan X, Tong Z, Zhang J, Zhang W, Shi L
International immunopharmacology 2026 Jan 1;168(Pt 2):115918
International immunopharmacology 2026 Jan 1;168(Pt 2):115918
Soufeng Yuchuan formula alleviates asthma airway inflammation and suppresses the progression of asthma by inhibiting ferroptosis in airway epithelial cells.
Mumu W, Xiaoyu Y, Yujing Z, Xinxin Z, Yongbin Y
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):73-84
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2026 Feb;46(1):73-84
Overexpression of OTUD5 in IPSCs-derived extracellular vesicles promotes angiogenesis after myocardial infarction by inhibiting endothelial cell ferroptosis.
Lu D, Chen D, Cao R, Zhang X, Liang J, Zhu F, Si K, Jiang W
Nutrition, metabolism, and cardiovascular diseases : NMCD 2026 Feb;36(2):104374
Nutrition, metabolism, and cardiovascular diseases : NMCD 2026 Feb;36(2):104374
An activatable polymeric nano-spy for reversing the progression of diabetic osteoporosis.
Li S, He Z, Zhu R, Qiao W, Li Q, Miao Q, Liu L
Biomaterials 2026 Feb;325:123637
Biomaterials 2026 Feb;325:123637
Progesterone receptor membrane component 1 (PGRMC1) regulates Heme trafficking through mitochondria-ER junctions.
Piel Iii RB, Obi CD, Viana MP, Willoughby MM, Martinez-Guzman O, Wadley A, Jami-Alahmadi Y, Wohlschlegel JA, Hicks KG, Rutter J, Maschek JA, Catrow JL, Cox J, Reddi AR, Khalimonchuk O, Medlock AE
Journal of inorganic biochemistry 2026 Feb;275:113093
Journal of inorganic biochemistry 2026 Feb;275:113093
Radiotherapy combined with anti-PD-1 immunotherapy promotes ferroptosis-driven control of hepatocellular carcinoma.
Dou T, Zhu X, Li H, Wang R, He J, Geng H, Zhang W, Yu Q, Zhao H, Yang H
Genes and immunity 2026 Feb;27(1):91-105
Genes and immunity 2026 Feb;27(1):91-105
Curcumin pretreatment enhances the capacity of BMSC exosomes to attenuate renal ischemia-reperfusion injury by ferroptosis suppression via miR-16-5p/Smad3/Mb axis.
Chen B, Chen J, Shen Z, Liu S, Mei Y, Cai H, Li K, Peng Z, Zhang L, Wang W, Lu S
Stem cell research & therapy 2026 Feb 9;17(1)
Stem cell research & therapy 2026 Feb 9;17(1)
SIRT1-mediated FABP4 destabilization attenuates fibrosis and ferroptosis in non-alcoholic fatty liver disease.
Qiu H, Chen K, Qiu Y, Yang Y, Wang T, Wang W, Jiang L
Clinical and experimental medicine 2026 Feb 6;26(1):129
Clinical and experimental medicine 2026 Feb 6;26(1):129
Hydroxytyrosol Prevents Metabolic-Associated Steatohepatitis by Inhibiting SOCS2-Mediated Ferroptosis in High-Fat Diet Mice.
Yi D, Wu Z, Li X, Shao B, Xiao Y, Li T, Zhang X, Zhu J, Yang T, Deng Y, Huang T, Qiu T, Bai J, Shi X, Wu C, Wu Z, Sun X, Wang N
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Journal of agricultural and food chemistry 2026 Feb 25;74(7):6265-6277
Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism.
Nemeth CL, Sisman M, Zhang J, Shin HG, Li X, Turk B, Fatemi A, Nguyen T, Mallack E
Annals of clinical and translational neurology 2026 Feb 24;
Annals of clinical and translational neurology 2026 Feb 24;
METTL3-mediated m6A modification of TIFA mRNA promotes tubular cell pyroptosis in acute kidney injury.
Ji ML, Peng LJ, Zhu Q, Cheng XR, Suo XG, Wang F, Wei J, Wang ZJ, Sun T, Zhang MM, Wang YF, Shao BY, Guo JB, Li HD, Xie SS, Li C, Ge QL, Dong YH, Li XY, Jin J, Yu JT, Yang C, Meng XM, Chen HY, Wen JG, Wang JN
Free radical biology & medicine 2026 Feb 16;244:68-83
Free radical biology & medicine 2026 Feb 16;244:68-83
Carboxymethyl chitosan-based injectable hydrogel immobilizing single-atom nanozymes for localized ROS amplification and ferroptosis-enhanced postoperative oral cancer therapy.
Qi M, Hong Y, Liu Y, Wang H, Xiong Y, Tang Y, Ma M, Gao Z, Zhang D
Carbohydrate polymers 2026 Feb 1;373:124668
Carbohydrate polymers 2026 Feb 1;373:124668
Multi-omics unravels multiple pharmacological actions in a murine model of infantile hemangioma receiving oxymatrine therapy.
Wang Y, Peng J, Qiu M, Dai Y, Wang S, Ou J, Yan J
Discover oncology 2026 Feb 1;17(1)
Discover oncology 2026 Feb 1;17(1)
Low, plasma level‑informed native curcumin concentrations fail to induce cell death in human lung and colorectal cancer cells.
Imtiaz I, Schloss J, Bugarcic A
Pharmaceutical biology 2026 Dec;64(1):471-486
Pharmaceutical biology 2026 Dec;64(1):471-486
lncRNA MALAT1-mediated regulation of cholesterol-oxidative stress-iron metabolic dysregulation by paeoniflorin in osteoarthritic chondrocytes.
Fu C, Lan S, Lin Y, Chen D, Yang Z, Chen C, Chen Y, Yuan Y, Zhong W, Lin Q, Huang Z
Pharmaceutical biology 2026 Dec;64(1):278-294
Pharmaceutical biology 2026 Dec;64(1):278-294
EP300 attenuates ferroptosis and stimulates proliferation, migration, and fibrosis of keloid fibroblasts via YY1/GPX4 axis.
Jin J, Wang K, Lu C, Yao C, Xie F
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-16
Cell cycle (Georgetown, Tex.) 2026 Dec;25(1):1-16
Hippocampal HDAC7 induces perioperative neurocognitive disorders via an NF-κB-MFN2-ACSL4 ferroptosis pathway.
Guo J, Chi W, Zhang K, Huang Y, Zhang B, Guo X, Meng F
Cellular signalling 2026 Aug;144:112531
Cellular signalling 2026 Aug;144:112531
Mitochondrial IRF3 drives pulmonary fibrosis by impairing mitophagy and triggering ferroptosis.
Jiashu Z, Jingbao L, Hua F, Meiqi S, Jing L, Mengyao W, Wei Z
Cellular signalling 2026 Aug;144:112517
Cellular signalling 2026 Aug;144:112517
NUPR1 and LCN2: Potential Therapeutic Targets for Colorectal Cancer Via Modulating Cell Viability, Migration, and Ferroptosis-Related Pathways.
Luo D, Luo X, Qian S, Liu J
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70809
Journal of biochemical and molecular toxicology 2026 Apr;40(4):e70809
Application of a novel myristoylproteomics approach identifies GLIPR2 as a key pro-ferroptotic substrate in non-small cell lung cancer.
Wang Y, Guo S, Guo W, Tian X, Miao Y, Qiu S, Xue X, Wang Y, Cui J, Xu X, Wang J, Zhang X
Materials today. Bio 2026 Apr;37:102945
Materials today. Bio 2026 Apr;37:102945
Puerarin promotes nerve regeneration and functional recovery after peripheral nerve injury by inhibiting ACSL4-dependent ferroptosis.
Sun T, Huang L, Zhao Y, Sun Q, Luo X, Wu Z, Sun J, Li M, Huo Q, Wang H
International journal of biological macromolecules 2026 Apr;357:151404
International journal of biological macromolecules 2026 Apr;357:151404
NRF2-TERT-ACSL4 pathway inhibits ferroptosis and regulates cytoskeletal dynamics to mitigate ovarian aging.
Chen Y, Zhang J, Cui S, Zhang W, Xu C, Cheng H, Zhang L, Liu Y, Zhang X, Yin Z, Cao Y, Liang D, Yu B
International journal of biological macromolecules 2026 Apr;357:151325
International journal of biological macromolecules 2026 Apr;357:151325
Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4-Mediated Ferroptosis.
Ren J, Wu S, Su T, Li H, Ding J, Chen F, Mo J, Li J, Wang Z, Han L, Wu Z
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14973
Small (Weinheim an der Bergstrasse, Germany) 2026 Apr;22(22):e14973
Resveratrol dual efficacy in high-altitude hypoxia and NAFLD: inhibits ferroptosis by modulating key proteins, including HIF-1α, ACSL4, and TfR1.
Zhao M, Mu H, Ji Q, Song J, Zheng F, Liu T, Li W, Wang R
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157992
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157992
Apigenin-5-O-glucoside alleviates hepatic fibrosis through NOX4-mediated ferroptosis in zebrafish.
Li M, Deng K, Cheng J, Shi H, Li Y, Wang Y, Wen J, Lv Z, Huang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157956
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157956
Computational-experimental integration reveals PPARγ/Nrf2-GPX4 dual-targeting by combined selenomethionine-magnolol as a novel therapy for sarcopenic obesity.
Li Z, Liu B, Zhou L, Chen N, Wang Y, Yang S, Fan X, Wang Y, Chen X
Free radical biology & medicine 2026 Apr 7;251:243-255
Free radical biology & medicine 2026 Apr 7;251:243-255
PDK4 acts via hippo signaling to inhibit ferroptosis and reduce gemcitabine sensitivity in pancreatic cancer.
Jin L, Pan M, Yuan X, Zhu X, Gao T, Chen C
Journal of molecular histology 2026 Apr 22;57(3)
Journal of molecular histology 2026 Apr 22;57(3)
Downregulation of SELENOS Suppresses the Progression of Renal Cell Carcinoma by Activating Ferroptosis.
Li Q, Wu Y, Xu Y, Shi H, Xu J, Xu S
Biological trace element research 2026 Apr 22;
Biological trace element research 2026 Apr 22;
Genome-wide CRISPR screen identifies TAF1C as an epigenetic determinant of lipid deposition via ACSL4-dependent ferroptosis in MASLD.
Gong Y, Chen J, Zhang F, Huang R, Mai L, Xu Y, Zhao W, Wei X, Zheng J, Liu X, Chen J
Journal of advanced research 2026 Apr 22;
Journal of advanced research 2026 Apr 22;
Aberrant expression of TRIM26 suppresses ferroptosis through regulating GPX4 protein stability in colorectal cancer.
Wu G, Zheng K, Xu S, Wang J, Xu J
Molecular biology reports 2026 Apr 16;53(1)
Molecular biology reports 2026 Apr 16;53(1)
Non-steroidal mineralocorticoid receptor antagonist finerenone ameliorates diabetic nephropathy via suppressing SLC7A11-mediated ferroptosis.
Yu L, Zhai Z, Wang Y, Wang L, Li Q, Guo Y, Liang Y, Tang L
International immunopharmacology 2026 Apr 15;175:116448
International immunopharmacology 2026 Apr 15;175:116448
USP53 Drives Ethanol-Induced Myocardial Injury by Promoting K63 Deubiquitination-Dependent RIPK1 Activation at K377.
Pan J, Liu X, Li X, Wang S, Zhao Y, Yuan C, Liu D, Wang L, Zhang M, Liu F, Zhang M, Dai S
Research (Washington, D.C.) 2025;8:0823
Research (Washington, D.C.) 2025;8:0823
H2S inhibits high glucose-induced osteoblast injury by inhibiting ferroptosis in diabetic osteoporosis in vitro.
Shi Q, Chen F, Wu W
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e14679
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2025;58:e14679
PROTAC-Surufatinib Suppresses Pancreatic Neuroendocrine Neoplasms Progression by Inducing Ferroptosis through Inhibiting WNT/β-catenin Pathway Mediated by HMOX1.
Xue B, Yan L, Ye M, Gu D, Qian J, He N, Hu P, Lu F, Lu X, Liu M, Xu L, Bai J, Wang Y, Zhu G, Tang Q
International journal of biological sciences 2025;21(6):2476-2492
International journal of biological sciences 2025;21(6):2476-2492
TRIM32 promotes neuronal ferroptosis by enhancing K63-linked ubiquitination and subsequent p62-selective autophagic degradation of GPX4.
Zhou X, Zhao Y, Huang S, Shu H, Zhang Y, Yang H, Ren Y, Zhou X, Liu W, Song T, Zhao J, Ma J
International journal of biological sciences 2025;21(3):1259-1274
International journal of biological sciences 2025;21(3):1259-1274
Pan-cancer analysis and validation show GTF2E2's diagnostic, prognostic, and immunological roles in regulating ferroptosis in endometrial cancer.
Zhang N, Qin X, Liu J, Han K, Kang M, Zhu Z, Zhang D, Zhong F
PloS one 2025;20(4):e0321983
PloS one 2025;20(4):e0321983
Mechanism of a Novel Complex: Zinc Oxide Nanoparticles-Luteolin to Promote Ferroptosis in Human Acute Myeloid Leukemia Cells in Vitro.
Wang W, Li Z, Lyu C, Wang T, Han C, Cui S, Wang J, Xu R
International journal of nanomedicine 2025;20:4035-4050
International journal of nanomedicine 2025;20:4035-4050
Self-Assembled Carrier Free Oligomeric Proanthocyanidin/Tetrandrine Nanoparticles Ameliorate Osteoarthritis via Anti-Inflammatory and Anti-Ferroptotic Pathways.
Xing C, Wu Y, Huang Y, Li W, Wang X, Chen H
International journal of nanomedicine 2025;20:13165-13181
International journal of nanomedicine 2025;20:13165-13181
MXene-Mediated Nanocarrier Delivery Enhances the Chondroprotective Effects of Quercetin in Experimental Osteoarthritis.
Gan K, Li J, Zhang X, Feng Z, Liu J, Zhao F
International journal of nanomedicine 2025;20:11553-11567
International journal of nanomedicine 2025;20:11553-11567
Comprehensive Analysis of Ferroptosis Markers in Lupus Nephritis Based on Bioinformatics Analysis and Experimental Validation.
Zhang S, Hu W, Huang C, Lin X, Chen X
Journal of inflammation research 2025;18:10855-10871
Journal of inflammation research 2025;18:10855-10871
Ferroptosis-related genes as prognostic markers for survival and immunotherapy in triple-negative breast cancer: analysis of public databases and a single institution.
Xie Y, Tao Z, Wang B, Zhao Y, Chen X, Li B, Wang J, Chen G, Hu X
Therapeutic advances in medical oncology 2025;17:17588359251322291
Therapeutic advances in medical oncology 2025;17:17588359251322291
Exploring the mechanism of Qingre Yishen Xiaozheng formula in treating diabetic kidney disease via the HIF-1α/HO-1 signaling pathway: an integrated network pharmacology and experimental study.
Han F, Shou J, Wang Y, Tian Z, Zheng H, Liu L, Liu W
Frontiers in pharmacology 2025;16:1661050
Frontiers in pharmacology 2025;16:1661050
Integrating network analysis and experimental validation to reveal the ferroptosis-associated mechanism of acteoside in the treatment of diabetic nephropathy.
Luo Z, Zhang SJ, Tang JY, Deng Y, Kang Y, Zhang XH, Lu HM, Wang YX, Liu WJ, Ma Y
Frontiers in pharmacology 2025;16:1660227
Frontiers in pharmacology 2025;16:1660227
Stimulation of regulatory dendritic cells suppresses cytotoxic T cell function and alleviates DEN-induced liver injury, fibrosis and hepatocellular carcinoma.
Wang J, Gong P, Liu Q, Wang M, Wu D, Li M, Zheng S, Wang H, Long Q
Frontiers in immunology 2025;16:1565486
Frontiers in immunology 2025;16:1565486
Pan-cancer analysis reveals MTTP as a prognostic and immunotherapeutic biomarker in human tumors.
Wang W, Gao Y, Liu Y, Xia S, Xu J, Qin L, Jia Y, Qin Y
Frontiers in immunology 2025;16:1549965
Frontiers in immunology 2025;16:1549965
Yersiniabactin produced by Escherichia coli promotes intestinal inflammation through lipid peroxidation and ferroptosis.
Wang H, Chen B, Xiao P, Han D, Gao B, Yan Y, Zhao R, Pan T, Zhang J, Zhou M, Lv L, Gao H
Frontiers in microbiology 2025;16:1542801
Frontiers in microbiology 2025;16:1542801
Berbamine attenuates hind limb ischemia-reperfusion injury by eliminating lipid ROS and inhibiting p65 nuclear translocation.
Zheng L, Zhao B, Ji R, Zhang Z, Liu Y, Zhao X, Cai J, Qiao T
Frontiers in pharmacology 2025;16:1509860
Frontiers in pharmacology 2025;16:1509860
Gallic acid protects intervertebral disc cells from ferroptosis and alleviates intervertebral disc degeneration by regulating key factors of oxidative stress.
Zhu Z, Huang Z, Zhang C, Xu B, Chen H, Pei S, Zhang B, Jie L, Shi X, Liu Y, Li Y, Shen X
Frontiers in pharmacology 2025;16:1501725
Frontiers in pharmacology 2025;16:1501725
Bioactive natural alkaloid 6-Methoxydihydrosanguinarine exerts anti-tumor effects in hepatocellular carcinoma cells via ferroptosis.
Han L, Gao C, Jin X, Li Y, Chen L, Li D, Deng Q, Bian X
Frontiers in pharmacology 2025;16:1500461
Frontiers in pharmacology 2025;16:1500461
Integrating oxygen-boosted sonodynamic therapy and ferroptosis via engineered exosomes for effective cancer treatment.
Wu M, Zhang Z, Li D, Ruan X, Yang J, Chen S, Li X, Ling W
Theranostics 2025;15(1):68-85
Theranostics 2025;15(1):68-85
Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma.
Zhao Q, Wang Y, Ding L, Li Z, Wang M, Huang Y, Cao Q, Sun Y, Guo X
Frontiers in oncology 2025;15:1532555
Frontiers in oncology 2025;15:1532555
Linoleic acid metabolite 13-Hydroxyoctadecadienoic acid as a biphasic ferroptosis modulator in granulosa cells: multi-omics analysis of ovine atretic follicles.
Song Y, Hai E, He L, Zhang N, Zhang N, Wang J, Sun Y, Zeng D, Zhang J
Frontiers in cell and developmental biology 2025;13:1610621
Frontiers in cell and developmental biology 2025;13:1610621
Modified Sanjia Powder ameliorates cognitive impairment and exerts neuroprotective effects in 5 × FAD mice: insights from quantitative proteomics.
Wang Y, Liu C, Zheng X, Wang Z, Wang Y, Geng Y, Yang J, Wei K, Chen X
Frontiers in nutrition 2025;12:1699142
Frontiers in nutrition 2025;12:1699142
Bioinformatic analysis, clinical implications and experimental validation of ferroptosis-related feature gene in IgA nephropathy: focus on DUSP1.
Liu T, Pan T, Chang M, Fu S, Xu H, Wu H, Xu Z, Cheng Y
Frontiers in medicine 2025;12:1612200
Frontiers in medicine 2025;12:1612200
Down-regulation of PCK2 enhanced the radioresistance phenotype of nasopharyngeal carcinoma.
He Y, Yan L, Zhang R, Yang R, Kong Z, Wang X
International journal of radiation biology 2025;101(5):499-509
International journal of radiation biology 2025;101(5):499-509
The role and mechanism of PGC-1α in oxLDL-induced ferroptosis of vascular endothelial cells.
Li J, He P, Zhang Y, Zhao R, Shen C, Li C, Liu W, Liu Z, Long X, Wang Y, Shi B
Atherosclerosis plus 2025 Sep;61:1-11
Atherosclerosis plus 2025 Sep;61:1-11
Microplastic exposure induces preeclampsia-like symptoms via HIF-1α/TFRC-mediated ferroptosis in placental trophoblast cells.
Jia H, Liu S, Wang W, He P, Zhao F, Xu X
Toxicology 2025 Sep;516:154197
Toxicology 2025 Sep;516:154197
Gallium maltolate and cisplatin co-treatment effectively targets triple-negative breast cancer in spheroid and mouse models.
Yang YW, Hsieh YC, Liu CY, Pan CK, Pan ZY, Lo KY
Toxicology and applied pharmacology 2025 Sep;502:117460
Toxicology and applied pharmacology 2025 Sep;502:117460
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity-Induced Corneal Epitheliopathy.
Chu G, Wang J, Wang Z, Cai X, Shi S, Qing Q, Zhong Y, Zhang Q
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2025 Sep;41(7):397-407
Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis.
Wu Y, Li J, Zhai W, Liu W, Wu H, Liu H, Min J, Wang F, Liu JX
Neurobiology of disease 2025 Sep;213:107027
Neurobiology of disease 2025 Sep;213:107027
LncRNA 91234.1 targets PRMT1/ASCL4/GPX4 axis to regulate formaldehyde-induced cardiomyocyte ferroptosis and congenital heart disease.
Zhao S, Sun P, Wang C, Li X, Xiu Z, Tian Y, Song X, He X, Yu T, Jiang Z
Journal of molecular and cellular cardiology 2025 Sep;206:76-90
Journal of molecular and cellular cardiology 2025 Sep;206:76-90
An SPR-based active ingredient recognition strategy for identifying PLK1-targeting withanolides as natural ferroptosis inducers.
Zhu R, Yan H, Xu W, Liang J, Xiang K, Liu Y, Yang Y, Li H, Chen L
Bioorganic chemistry 2025 Sep;164:108849
Bioorganic chemistry 2025 Sep;164:108849
Inhibition of Iron Death by Lycium barbarum Polysaccharides Ameliorates Myocardial Injury in Sepsis: A Pharmacological Mechanism Study Based on the NRF2/HO-1 Pathway.
Niu Z, Hu Y, Yang L, Meng X, Chen M, Bai X, Liu R, Tang Y, Yang L, Xue W
Food science & nutrition 2025 Sep;13(9):e70835
Food science & nutrition 2025 Sep;13(9):e70835
Crotonoside induces ferroptosis and mitochondrial dysfunction in AML.
Ma C, Wang J, Cui S, Xu R
European journal of pharmacology 2025 Sep 5;1002:177859
European journal of pharmacology 2025 Sep 5;1002:177859
BRD-K20733377 inhibits ferroptosis and alleviates intervertebral disc degeneration via the STAT3/NFKB1 axis: a multiapproach study.
Sun H, You X, Li Z, Li Z, Hua B, Liu C, Zhang Y, Wu H, Zai S, Zhang L
Stem cell research & therapy 2025 Sep 29;16(1):531
Stem cell research & therapy 2025 Sep 29;16(1):531
Yishen Qufeng formula mediates ferroptosis to improve renal fibrosis in unilateral ureteral obstruction rats.
Gao J, Wei Y, Zhang W, Yu Y, Ge H, Tian F, Zhou E
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120376
Journal of ethnopharmacology 2025 Sep 25;353(Pt B):120376
SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer.
Zhou X, Wang G, Wu Y, Wu M, Zhai X, Tian C, Prochownik EV, Jiang C, Li Y
Cell reports 2025 Sep 23;44(9):116139
Cell reports 2025 Sep 23;44(9):116139
3-hydroxyanthranilic acid analog mitigates ischemia-reperfusion injury by inhibiting cardiomyocyte ferroptosis through the activation of Nrf2/HO-1/GPX4.
Yang HY, Liu ZY, Xu ZQ, Teng LS, Sheng XH, Zhang G, Zhang FS
International immunopharmacology 2025 Sep 23;162:115117
International immunopharmacology 2025 Sep 23;162:115117
Dovitinib Ameliorates Inflammation-Related Diseases by Inhibiting Necroptosis and Ferroptosis.
Lin Y, Feng J, Zhao M, Zhang L, Li Y, Chen X, Lin C, Lin J, Lin Q, Li J, Wu L, Li L
ACS chemical biology 2025 Sep 19;20(9):2191-2203
ACS chemical biology 2025 Sep 19;20(9):2191-2203
Protective Effect of Hepcidin on Sepsis-Associated Acute Kidney Injury via Activating the Nrf2/GPX4 Signaling Pathway.
Guo LB, Wu SS, Xu F, Chen XX, Fan H
Current issues in molecular biology 2025 Sep 18;47(9)
Current issues in molecular biology 2025 Sep 18;47(9)
Circ_0002638 drives squamous cell lung cancer (LUSC) progression and chemotherapy resistance by inhibiting ferroptosis via SENP1-mediated deSUMOylation of ACSL4.
Wang DG, Wang J, Gao J, Ao YQ, Long X, Zhu SQ, Zeng ZH, Zhang LX, Chen SW, Pei X, Wu YB
Life sciences 2025 Sep 1;376:123728
Life sciences 2025 Sep 1;376:123728
A galacturonan from sea buckthorn (Hippophae rhamnoides L.) berry modulates dyslipidemia by promoting hepatic lipolysis and mitochondrial oxidation.
Sun Y, Ni W, Wang D, Ren J, Zhao D, Yu S, Liu S, Zhang S, Wang S, Wang W, Liu M
Carbohydrate polymers 2025 Sep 1;363:123708
Carbohydrate polymers 2025 Sep 1;363:123708
Zearalenone induces intestinal damage and flora disturbance in rats by triggering ferroptosis via the system Xc(-)-GSH-GPX4 signaling pathway.
Huangfu B, Li J, Xu T, Ren X, Zhang R, Chen Y, Wang J, Huang K, He X
Ecotoxicology and environmental safety 2025 Sep 1;302:118600
Ecotoxicology and environmental safety 2025 Sep 1;302:118600
Sodium tanshinone IIA sulfonate alleviates osteoarthritis through targeting SIRT1.
Xu M, Sun X, Ma X, Qin Z, Gao X, Jin X, Sun H
Chinese medicine 2025 Sep 1;20(1):142
Chinese medicine 2025 Sep 1;20(1):142
cZFP609 Tethering BiP Alleviates Cartilage Degradation in Osteoarthritis via Remedying Aberrant ER-Mitochondrial Contacts.
Song Y, Luo JL, Zhang F, Shi J, Du S, Jiang HB, Zhang WD, Chen SY, Zhang DD, Kong P, Gao Y, Han M, Li H
MedComm 2025 Oct;6(10):e70405
MedComm 2025 Oct;6(10):e70405
NOX4 Regulates NLRP3 by Inhibiting the Ubiquitination of LRRC8A to Promote Ferroptosis in Nucleus Pulposus Cells.
Zhang F, Cui D, Wang Z, Li Y, Wang K, Lu H, Yu H, Jiao W, Cui X
Inflammation 2025 Oct;48(5):3111-3129
Inflammation 2025 Oct;48(5):3111-3129
TSLP mitigates post-infarction myocardial remodeling by promoting eosinophil recruitment and inhibiting JAK1-STAT5-mediated ferroptosis.
Wang Y, Cao C, Fu T, Yu F, Qi J, Liu G, Zhang J
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2269-2286
Apoptosis : an international journal on programmed cell death 2025 Oct;30(9-10):2269-2286
Ferritinophagy Is Involved in the Advanced Glycation End Products-Induced Ferroptosis of Vascular Endothelial Cells in Diabetes Mellitus.
Huang Y, Jin Y, Hu J, Li M, Tian M, Zeng G, Huang R
Journal of cellular and molecular medicine 2025 Oct;29(20):e70857
Journal of cellular and molecular medicine 2025 Oct;29(20):e70857
Gut microbiota derived butyrate enhances ferroptosis sensitivity in endometriosis through FFAR2/PPAR-γ/PINK1/Parkin mediated mitophagy.
Gou Y, Ding J, Wang H, Bai R, Wang H, Wang B, Cao Y, Liu J, Cui J, Zhang Z
Free radical biology & medicine 2025 Oct;238:640-652
Free radical biology & medicine 2025 Oct;238:640-652
RTA-408 overcomes cisplatin-resistant lung cancer by inhibiting WWP1-mediated NCOA4 ubiquitination to induce ferritinophagy and ferroptosis.
Wang X, Liu T, Fei Y, Zhang S, Yang Y, Chen Z, Zhu R, Deng S, Zhang T, Wu D, Xu Y
Free radical biology & medicine 2025 Oct;238:595-610
Free radical biology & medicine 2025 Oct;238:595-610
TRIM34 inhibits triple-negative breast cancer progression by attenuating fatty acid synthesis via facilitating FASN ubiquitination.
Li Y, Shan J, Liu S, Shen Y, Niu L, Mao Q, Chen X
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167958
Biochimica et biophysica acta. Molecular basis of disease 2025 Oct;1871(7):167958
Duhuo Jisheng decoction alleviates intervertebral disc degeneration by inhibiting nucleus pulposus cell ferroptosis via the exosome-mediated miR-19b-3p/ACSL4 axis.
Feng J, Miao H, Xiao Z, Xu L, Wang Y, Cao X, Wang J, Wu Z, Xia P, Liu W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157113
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Oct;146:157113
Panx3 mediates ferroptosis via the AKT/mTOR signaling pathway in oral squamous cell carcinoma.
Li X, Zhao Y, Liu Y, Zhang CS, Xu ZY, Wang SR, Zhang TM, Zhang Y, Liang SX, Yan YB
Cellular signalling 2025 Oct;134:111908
Cellular signalling 2025 Oct;134:111908
Nanovesicles Synergistically Regulate Ferroptosis Characteristic Macrophage-Induced Angiogenesis via Ferritin Heavy Chain 1/Glutathione Peroxidase 4 Pathway to Promote Peripheral Nerve Regeneration.
Huo N, Xu G, Zhou H, Liu Y, Li S, Yang X, Liu J, Wang W, Yang N, Zhou N
ACS applied materials & interfaces 2025 Oct 8;17(40):55876-55894
ACS applied materials & interfaces 2025 Oct 8;17(40):55876-55894
SLC25A10 promotes cisplatin resistance by inhibiting ferroptosis in cervical cancer.
Ma C, Lu X, Ni C, Gao Y, Yang F, Chen S, Du Y, Zhao F, Cao Y, Huang H
Cell death discovery 2025 Oct 7;11(1):447
Cell death discovery 2025 Oct 7;11(1):447
GSTP1-mediated inhibition of ACSL4-dependent ferroptosis via JNK pathway in DOX-induced cardiomyopathy.
Wu M, Zhao Y, Li D, Hu X, Zhou J, Chen S, Yang X, Li Z, Ruan X, Yang J, Ling W
Chinese medical journal 2025 Oct 5;138(19):2498-2510
Chinese medical journal 2025 Oct 5;138(19):2498-2510
Microwave dynamic therapy induces ferroptosis in colorectal cancer by targeting PTK2B to regulate STAT3-mediated GPX4 expression.
Zhou H, Zhang Z, Liu Z, Xiong L, Ran X, Liu J, Ran Y, Wen Y, Chen W, Xu J
Molecular biomedicine 2025 Oct 30;6(1):91
Molecular biomedicine 2025 Oct 30;6(1):91
Ginsenoside Ro Targets BCAT1/2 to Suppress Ferroptosis: A Novel Therapeutic Strategy for Ischemic Cardioprotection.
Liu J, Wang F, Bai J, Qu S, Tao S, Liu C, Wang Q, Ding W, Lai Q, Zhang J
Journal of agricultural and food chemistry 2025 Oct 22;73(42):26683-26699
Journal of agricultural and food chemistry 2025 Oct 22;73(42):26683-26699
Integrated Multiomic Analysis Reveals the Therapeutic Potential of Danhong Injection in Mitigating Radiation-Induced Heart Disease by Modulating Ferroptosis.
Wang BW, Wang G, Zhang Z, Lu WJ, Li YL, Shu YB, Xie P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71106
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Oct 15;39(19):e71106
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis.
Zhao T, Chen C, Zhao W, Han J, Omar Jan M, Lou H, Chen Z, Liu X, Jing S
European journal of pharmacology 2025 Oct 15;1005:178046
European journal of pharmacology 2025 Oct 15;1005:178046
SPP1 exacerbates ischemic stroke by promoting ferroptosis induced brain injury.
Zhou Y, Zhang L, Yan X, Yang Z, Kou Z, Jiang L, Zhu W, Song J, Li J
Biochemical and biophysical research communications 2025 Oct 1;783:152627
Biochemical and biophysical research communications 2025 Oct 1;783:152627
SOCS1 orchestrates ferroptotic renal injury via GPX4 ubiquitination in hyperuricemia.
Zhang R, Fu X, Zhao X, Wang K
Experimental cell research 2025 Oct 1;452(2):114774
Experimental cell research 2025 Oct 1;452(2):114774
NDUFA8 promotes cell viability and inhibits ferroptosis and cisplatin sensitivity by stabilizing Fe-S clusters in cervical cancer.
Xiang H, Sun J, Kong L, Wang Y, Qiu X, Zeng J, Li G, He J
Naunyn-Schmiedeberg's archives of pharmacology 2025 Nov;398(11):15547-15559
Naunyn-Schmiedeberg's archives of pharmacology 2025 Nov;398(11):15547-15559
PSAT1 knockdown mediated VDAC1 oligomerization promotes ferroptosis and suppresses cell proliferation in esophageal squamous cell carcinoma.
Ren R, Fan T, Li Y, Li C, Jin F, Gao H, Wang X, Xu Y, Li X, Li S, Liu H
International journal of biological macromolecules 2025 Nov;330(Pt 4):148112
International journal of biological macromolecules 2025 Nov;330(Pt 4):148112
SPINT2 inhibits NEDD4L-mediated ACSL4 ubiquitination to promote ferroptosis and suppress gallbladder cancer progression.
Ye P, Yang X, Wang H, Ren Y, Gao M, Wang Y, Guo Y, Sun Y, Xu J
International journal of biological macromolecules 2025 Nov;330(Pt 3):148141
International journal of biological macromolecules 2025 Nov;330(Pt 3):148141
Structural characterization and functional role of SLC7A6 in GSSG transport and Ferroptosis regulation.
Yan G, Chen M, Lu Z, Huang H, Wang X, Qin W, Mo S, Zhong P, Han C, Ye X
International journal of biological macromolecules 2025 Nov;330(Pt 3):148008
International journal of biological macromolecules 2025 Nov;330(Pt 3):148008
Silymarin ameliorates diet-induced gallstone formation by regulating gut microbiota-derived GCDCA to suppress ferroptosis-ROS-NFκB signaling pathway.
Wang Q, Han C, Zheng Y, Liu X, Lv Z, Du Z, Liu T, Hao C, Meng X, Li T, Xue D
Free radical biology & medicine 2025 Nov;239:496-512
Free radical biology & medicine 2025 Nov;239:496-512
Botulinum Toxin Type A as a Therapeutic Agent in Epilepsy: Attenuation of Neuronal Ferroptosis and Cognitive Dysfunction.
Li S, Huang Z, Ma Y, Zheng Y, Du M, Lian Y
Brain and behavior 2025 Nov;15(11):e70930
Brain and behavior 2025 Nov;15(11):e70930
Gut microbiota-bile acid metabolic disorder involved in the cognitive impairments in epilepsy through HO-1 dependent ferroptosis.
Li X, Ji J, Li J, Li S, Luo Q, Gu M, Yin X, Zhang M, Fan H, Yao R
Journal of pharmaceutical analysis 2025 Nov;15(11):101291
Journal of pharmaceutical analysis 2025 Nov;15(11):101291
Ferroptosis promotes sepsis-related lung injury via endothelial cell senescence.
Yao Y, Wang S, Shi W, Yang L, Tian Y, Wang D, Xia D
Cellular signalling 2025 Nov;135:112018
Cellular signalling 2025 Nov;135:112018
Cardiomyocyte-specific knockout of Oip5-as1 exacerbates MI/R-induced ferroptosis via p62/KEAP1/NRF2 inhibition.
Hu S, Chen C, Wei S, Bai M, Niu X
Cellular signalling 2025 Nov;135:112007
Cellular signalling 2025 Nov;135:112007
Palmitic Acid Induces Ferroptosis in Retinal Microvascular Endothelial Cells by Palmitoylation of Keap1 to Affect Diabetic Retinopathy.
Mao Z, Yang W, Chao Y, Chen Z, Zou Y
Investigative ophthalmology & visual science 2025 Nov 3;66(14):41
Investigative ophthalmology & visual science 2025 Nov 3;66(14):41
Sestrin2 ameliorates LPS-induced cardiomyocyte injury by inhibiting ferroptosis via the Nrf2/HO-1 pathway.
Yang Y, Yang P, Zheng Z, Tian Q
European journal of medical research 2025 Nov 28;31(1):3
European journal of medical research 2025 Nov 28;31(1):3
A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunotherapy.
Peng H, Chang A, Zhang H, Xu X, Wang W, Zhang K, Yang J, Xie S, Peng X, Yin X, Qu C, Fu J, Ni J, Dong X
Journal of nanobiotechnology 2025 Nov 25;23(1):799
Journal of nanobiotechnology 2025 Nov 25;23(1):799
Lipid metabolism-related genes correlate with immune microenvironment and regulate the efficacy of immunotherapy via ferroptosis in melanoma.
Zhang H, Chen Y, Guo S, Guo W
Discover oncology 2025 Nov 25;16(1):2297
Discover oncology 2025 Nov 25;16(1):2297
ALKBH5-mediated RNA N6-methyladenosine demethylation protects against myocardial I/R-induced injury via FSP1-dependent inhibition of ferroptosis.
Tian Z, Zhou J, Kuang L, Wang L, Hua H, Tan W, Hua Y, Yan H, Liu Z, Wen T
Journal of molecular histology 2025 Nov 24;57(1):5
Journal of molecular histology 2025 Nov 24;57(1):5
B355252 Targets UCP2 to Rescue Intracerebral Hemorrhage-Induced Injury by Promoting Mitochondrial Fusion and Inhibiting Ferroptosis.
Han B, Ma C, Liu Y, Shi C, Guo J, Bai M, Duan M, Meng S, Liu J, He M
Molecular neurobiology 2025 Nov 15;63(1):43
Molecular neurobiology 2025 Nov 15;63(1):43
Chrysin Improves Cognitive Dysfunction in Rats with Intracerebral Hemorrhage by Regulating the Nrf2/GPX4 Pathway to Inhibit Ferroptosis.
Guo D, Shao Z, Liu D, Guan Y, Lian D, Feng J, Zhang C, Peng H
Molecular neurobiology 2025 Nov 13;63(1):35
Molecular neurobiology 2025 Nov 13;63(1):35
Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury.
Teng LS, Ying ZD, Sun XH, Hou HC, Qiu SD, Liu P, Li KJ, Zhang L, Sheng XH
Chemico-biological interactions 2025 Nov 1;421:111724
Chemico-biological interactions 2025 Nov 1;421:111724
Ferroptosis-driven neurobehavioral impairment in zebrafish embryos: Mechanistic links to developmental dibutyl phthalate exposure.
Hou T, Guo Y, Tao L, Fan X
Environmental pollution (Barking, Essex : 1987) 2025 Nov 1;384:127009
Environmental pollution (Barking, Essex : 1987) 2025 Nov 1;384:127009
Sirt1 overexpression inhibits chondrocyte ferroptosis via Ftl deacetylation to suppress the development of osteoarthritis.
Xiong X, Huang H, Wang N, Zhou K, Song X
Journal of bone and mineral metabolism 2025 May;43(3):203-215
Journal of bone and mineral metabolism 2025 May;43(3):203-215
Increased Trophoblast Cell Ferroptosis via HMGB1/ACSL4 Pathway Is Associated with Spontaneous Abortion.
Dong Y, Li Y, Tang W, Chen Q, Kong C
Reproductive sciences (Thousand Oaks, Calif.) 2025 May;32(5):1713-1722
Reproductive sciences (Thousand Oaks, Calif.) 2025 May;32(5):1713-1722
Adipose stem cells ameliorate erectile dysfunction in diabetes mellitus rats by attenuating ferroptosis through NRP1 with SLC7A11 interaction.
Luo JQ, Wang L, Liao ZQ, Lu BX, Luo CY, He HY, Ou Yang ZH, Duan SB, He SH, Wei AY, Zhang HB
Free radical biology & medicine 2025 May;232:40-55
Free radical biology & medicine 2025 May;232:40-55
Comprehensive analysis of ferroptosis-related long non-coding RNA and its association with tumor progression and ferroptosis in gastric cancer.
Huang S, Liu K, Liu Q, Tao S, Wang H
BMC gastroenterology 2025 May 8;25(1):349
BMC gastroenterology 2025 May 8;25(1):349
OTULIN orchestrates NCOA4-FTH1 complex to alleviate APAP-induced hepatocyte Ferroptosis.
Gao L, Chang X, Han Y, Li J, Meng Y, Yang X, Jiang Z
International immunopharmacology 2025 May 8;154:114490
International immunopharmacology 2025 May 8;154:114490
Cell-Free Fat Extract for the Treatment of Lumbar Disc Degeneration: A Novel Approach Using Adipose-Derived Biologic.
Xu C, Zhou X, Yang C, Zhou F, Xie Y
Biomedicines 2025 May 30;13(6)
Biomedicines 2025 May 30;13(6)
Melatonin inhibits salivary gland epithelial cell ferroptosis via the NRF2/HO-1/GPX4 signaling pathway in primary Sjögren's syndrome.
Weng X, Wang S, Wang Q, Wei M, Cheng B
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 May 24;74(1):84
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 May 24;74(1):84
Astilbin Alleviates IL-17-Induced Hyperproliferation and Inflammation in HaCaT Cells via Inhibiting Ferroptosis Through the cGAS-STING Pathway.
Xu X, Zhang H, Chang A, Peng H, Li S, Zhang K, Wang W, Yin X, Qu C, Dong X, Ni J
International journal of molecular sciences 2025 May 24;26(11)
International journal of molecular sciences 2025 May 24;26(11)
Arginine Deprivation Induces Quiescence and Confers Vulnerability to Ferroptosis in Colorectal Cancer.
Lin Y, Zhang Y, Huang T, Chen J, Li G, Zhang B, Xu L, Wang K, He H, Chen H, Liu D, Guo S, He X, Lan P
Cancer research 2025 May 2;85(9):1663-1679
Cancer research 2025 May 2;85(9):1663-1679
Tanshinone IIA Promotes Functional Recovery After Spinal Cord Injury by Inhibiting Neuron and Oligodendrocyte Ferroptosis Through the GPX4/ACSL4 Axis.
Xu L, Jiang G, Tan S, Ma Y, Song J, Gao Y, Wang G, Fan J, Yang Y, Yu X
Neurochemical research 2025 May 16;50(3):167
Neurochemical research 2025 May 16;50(3):167
Perfluorooctane sulfonate induced ferritinophagy via detyrosinated alpha tubulin-TRIM21-HERC2-regulated NCOA4 degradation in hepatocytes.
Feng R, Hu L, Yang W, Liang P, Li Y, Tian K, Wang K, Qiu T, Zhang J, Sun X, Yao X
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126101
Environmental pollution (Barking, Essex : 1987) 2025 May 15;373:126101
Mechanistic insights into the role of FAT10 in modulating NCOA4-mediated ferroptosis in pancreatic acinar cells during acute pancreatitis.
Liu L, Che B, Zhang W, Du D, Zhang D, Li J, Chen Z, Yu X, Ye M, Wang W, Li Z, Xie F, Wang Q, Chen L, Shao J
Cell death & disease 2025 May 15;16(1):385
Cell death & disease 2025 May 15;16(1):385
Platelet-Rich Plasma-Derived Exosome-Encapsulated Hydrogels Accelerate Diabetic Wound Healing by Inhibiting Fibroblast Ferroptosis.
Wang S, Wu J, Ren K, Zhang Y, Gao F, Chen Y, Chen C, Lu J
ACS applied materials & interfaces 2025 May 14;17(19):27923-27936
ACS applied materials & interfaces 2025 May 14;17(19):27923-27936
Autophagy Impairment-Derived SQSTM1 Accumulation Promotes Ferroptosis in Corneal Epithelial Cells Through ACSL4 in Dry Eye.
Zhang R, Liang L, Liao K, Zeng H, Yang X, Wang X, Wang B, Yuan J
Investigative ophthalmology & visual science 2025 May 1;66(5):23
Investigative ophthalmology & visual science 2025 May 1;66(5):23
The anti-Alzheimer's disease effects of ganoderic acid A by inhibiting ferroptosis-lipid peroxidation via activation of the NRF2/SLC7A11/GPX4 signaling pathway.
Lu Q, Shao N, Fang Z, Ouyang Z, Shen Y, Yang R, Liu H, Cai B, Wei T
Chemico-biological interactions 2025 May 1;412:111459
Chemico-biological interactions 2025 May 1;412:111459
MiR-370-3p regulate TLR4/SLC7A11/GPX4 to alleviate the progression of glucocorticoids-induced osteonecrosis of the femoral head by promoting osteogenesis and suppressing ferroptosis.
Zuo R, Cao B, Kong L, Wang F, Li S, Shan H, Guan J, Kang Q
Journal of orthopaedic translation 2025 Mar;51:337-358
Journal of orthopaedic translation 2025 Mar;51:337-358
SLC25A1 and ACLY maintain cytosolic acetyl-CoA and regulate ferroptosis susceptibility via FSP1 acetylation.
Li W, Han J, Huang B, Xu T, Wan Y, Luo D, Kong W, Yu Y, Zhang L, Nian Y, Chu B, Yin C
The EMBO journal 2025 Mar;44(6):1641-1662
The EMBO journal 2025 Mar;44(6):1641-1662
1,25-(OH)(2)D(3) improves SD rats high-altitude pulmonary edema by inhibiting ferroptosis and ferritinophagy in alveolar epithelial cells.
Wang Y, Su H, Lin X, Dai C, Cheng Q, Deng Z, Yang Y, Pu X
The Journal of steroid biochemistry and molecular biology 2025 Mar;247:106663
The Journal of steroid biochemistry and molecular biology 2025 Mar;247:106663
Delivery of exogenous miR-19b by Wharton's Jelly Mesenchymal Stem Cells attenuates transplanted kidney ischemia/reperfusion injury by regulating cellular metabolism.
Wu X, Wu X, Wang Z, Tian X, Zhang C, Cao G, Gu Y, Yan T
Drug delivery and translational research 2025 Mar;15(3):925-938
Drug delivery and translational research 2025 Mar;15(3):925-938
Induction of UBQLN1-mediated PGC1α stability by isoliensinine overcame hypoxia-induced resistance in liver cancer cells.
Xu X, Li W, Zhou Y, Wang M, Ji S, Xia S, Li Y, Guo X, Huan S, Wang F, Zhang F, Cheng H, Yin G, Zheng S
BioFactors (Oxford, England) 2025 Mar-Apr;51(2):e70008
BioFactors (Oxford, England) 2025 Mar-Apr;51(2):e70008
HAT1/HDAC2 mediated ACSL4 acetylation confers radiosensitivity by inducing ferroptosis in nasopharyngeal carcinoma.
Zhou P, Peng X, Zhang K, Cheng J, Tang M, Shen L, Zhou Q, Li D, Yang L
Cell death & disease 2025 Mar 6;16(1):160
Cell death & disease 2025 Mar 6;16(1):160
The YTHDF3-DT/miR-301a-3p /INHBA axis attenuates autophagy-dependent ferroptosis in lung adenocarcinoma.
Peng X, Yang R, Wang C, Peng W, Zhao Z, Shi S, Cai Q, He B, Wang L, Yu F, Wang X, Tao Y
Cancer letters 2025 Mar 31;613:217503
Cancer letters 2025 Mar 31;613:217503
Study on the mechanism of hsa_circ_0074763 regulating the miR-3667-3P/ACSL4 axis in liver fibrosis.
Cheng Y, Song T, Yao J, Wang Q, Meng C, Feng F
Scientific reports 2025 Mar 27;15(1):10548
Scientific reports 2025 Mar 27;15(1):10548
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis.
Pan Z, Gan C, Zhi S, Yang Y, Zhang Y, Li L, Zhang S, Huang Q
Journal of ethnopharmacology 2025 Mar 26;344:119532
Journal of ethnopharmacology 2025 Mar 26;344:119532
Ditan Decoction ameliorates vascular dementia-induced cognitive dysfunction through anti-ferroptosis via the HIF1α pathway: Integrating network pharmacology and experimental validation.
Gu M, Sun L, Yang J, Wang K, Wu F, Zheng L, Shen X, Lai X, Gong L, Peng Y, Xu S, Yang J, Yang C
Journal of ethnopharmacology 2025 Mar 26;344:119459
Journal of ethnopharmacology 2025 Mar 26;344:119459
A decrease in Flavonifractor plautii and its product, phytosphingosine, predisposes individuals with phlegm-dampness constitution to metabolic disorders.
Li L, Li T, Liang X, Zhu L, Fang Y, Dong L, Zheng Y, Xu X, Li M, Cai T, Zhao F, Xin M, Shao M, Guan Y, Liu M, Li F, Zhang C, Wang Q, Sun W, Zheng Y
Cell discovery 2025 Mar 17;11(1):25
Cell discovery 2025 Mar 17;11(1):25
Nrf2 ameliorates defective autophagic processes and thereby inhibits ferroptosis in acute pancreatitis by suppressing Beclin1-Slc7a11 complex formation.
Li J, Jia YC, Zhang H, Wang Z, Ding Y, Cao F, Wang G, Li F
Free radical biology & medicine 2025 Mar 16;230:294-308
Free radical biology & medicine 2025 Mar 16;230:294-308
A Deferoxamine-Loaded Microneedle Patch Enhances Healing of Radiation-Induced Skin Injury: Potential Involvement of Ferroptosis.
Tian K, Wu P, Gao S, Xu C, Xu W, Jia Z, Wang Y, Sheng L, Zhou X, Wu S, Wu L
ACS applied materials & interfaces 2025 Mar 12;17(10):15035-15049
ACS applied materials & interfaces 2025 Mar 12;17(10):15035-15049
Silencing of FZD7 Inhibits Endometriotic Cell Viability, Migration, and Angiogenesis by Promoting Ferroptosis.
Zhang Y, Yang H
Cell biochemistry and biophysics 2025 Jun;83(2):2471-2480
Cell biochemistry and biophysics 2025 Jun;83(2):2471-2480
Redox regulation of TRIM28 facilitates neuronal ferroptosis by promoting SUMOylation and inhibiting OPTN-selective autophagic degradation of ACSL4.
Liu W, Zhu Y, Ye W, Xiong J, Wang H, Gao Y, Huang S, Zhang Y, Zhou X, Zhou X, Ge X, Cai W, Zheng X
Cell death and differentiation 2025 Jun;32(6):1041-1057
Cell death and differentiation 2025 Jun;32(6):1041-1057
Quercetin-loaded exosomes delivery system prevents myopia progression by targeting endoplasmic reticulum stress and ferroptosis in scleral fibroblasts.
Zhao L, Dong X, Guo B, Song J, Bi H
Materials today. Bio 2025 Jun;32:101896
Materials today. Bio 2025 Jun;32:101896
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment.
Yi G, Li M, Zhou J, Li J, Song X, Li S, Liu J, Zhang H, Chen Z
Materials today. Bio 2025 Jun;32:101697
Materials today. Bio 2025 Jun;32:101697
Ochratoxin A-induced mitochondrial pathway apoptosis and ferroptosis by promoting glycolysis.
Zhou Y, Chen W, Feng S, Liu S, Chen C, Yao B, Shen XL
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1440-1452
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1440-1452
Nutrient deficiency-induced downregulation of SNX1 inhibits ferroptosis through PPARs-ACSL1/4 axis in colorectal cancer.
Qian LH, Wen KL, Guo Y, Liao YN, Li MY, Li ZQ, Li SX, Nie HZ
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1391-1409
Apoptosis : an international journal on programmed cell death 2025 Jun;30(5-6):1391-1409
CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation.
Tang Y, Ye J, Xu T, Sun Y, Meng W, Zhu L, Jia Z, Wu Q, Chen D, Wu F
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
Journal of cellular and molecular medicine 2025 Jun;29(12):e70590
MiR214-3p Ameliorates Diabetic Cardiomyopathy by Inhibiting Ferroptosis.
Chen P, Huang X, Wen W, Cao Y, Li W, Huang G, Huang Y, Hu Y, Ma T
Cardiovascular toxicology 2025 Jun;25(6):884-897
Cardiovascular toxicology 2025 Jun;25(6):884-897
Biochanin A mitigates colitis by inhibiting ferroptosis-mediated intestinal barrier dysfunction, oxidative stress, and inflammation via the JAK2/STAT3 signaling pathway.
Deng B, Wang K, He H, Xu M, Li J, He P, Liu Y, Ma J, Zhang J, Dong W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jun;141:156699
Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species.
Fu HJ, Zhou XY, Qin DL, Qiao Q, Wang QZ, Li SY, Zhu YF, Li YP, Zhou JM, Cai H, Huang FH, Yu L, Wang L, Wu AG, Wu JM, Zhou XG
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(22):e2416559
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(22):e2416559
Network pharmacology analysis reveals that coumestrol targets ZYX to inhibit ferroptosis and alleviate acute pancreatitis.
Chen J, Xu H, Gao L, Niu L, Huang Z, Liu S, Huang S, Chen Y, Li J, Tan P, Fu W
International immunopharmacology 2025 Jun 26;159:114948
International immunopharmacology 2025 Jun 26;159:114948
Chondrocyte-targeted α-Solanine through HIF-1α regulating glycolysis to reduce the ferroptosis of chondrocyte in osteoarthritis.
Li W, Liu Y, Wei M, Yang Z, Tang H, Huang W
International immunopharmacology 2025 Jun 26;159:114841
International immunopharmacology 2025 Jun 26;159:114841
Quercetin, as a Nutritional Supplement, Protects against Iron Overload-Induced Testicular Dysfunction via Inhibiting Ferroptosis.
Yuan W, Ji G, Wang X, Li W, Sun Z, Wei Z, Shi X, Hu H
Journal of agricultural and food chemistry 2025 Jun 25;73(25):15579-15595
Journal of agricultural and food chemistry 2025 Jun 25;73(25):15579-15595
Oxidized Albumin Induces Renal Tubular Cell Death and Promotes the Progression of Renal Diseases Through Ferroptosis.
Zhang Y, Jiang R, Shi Z, Sui Y, Cheng J, Suda M, Niimi M, Gao K, Fan J, Yao J
International journal of molecular sciences 2025 Jun 20;26(13)
International journal of molecular sciences 2025 Jun 20;26(13)
A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.
Zou X, Zhu Y, Shu H, Su X, Xiong J, Ye W, Tang P, Wang H, Gao Y, Song T, Zou Z, Cai W
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
The gut microbiota-mediated ferroptosis pathway: a key mechanism of ginsenoside Rd against metabolism-associated fatty liver disease.
Liu W, Zhou X, Xiao L, Huang X, Chang D, Zhong X, Zeng M, Xian Y, Zheng Y, Huang W, Huang R, Huang M
Chinese medicine 2025 Jun 10;20(1):83
Chinese medicine 2025 Jun 10;20(1):83
Ambient fine particulate matter induces cardiac fibrosis through triggering ferroptosis by heme degradation induced-iron overload.
Jiang J, Li Y, Chen Y, Wu Q, Ding S
Ecotoxicology and environmental safety 2025 Jun 1;297:118227
Ecotoxicology and environmental safety 2025 Jun 1;297:118227
MGST1 Inhibits Sevoflurane-Induced Ferroptosis and Activates the Wnt Pathway in HT22 Cells.
Gao S, Wang X, Shao Z, Chen J
Molecular neurobiology 2025 Jul;62(7):9497-9505
Molecular neurobiology 2025 Jul;62(7):9497-9505
Eburicoic acid inhibits endothelial cell pyroptosis and retards the development of atherosclerosis through the Keap1/Nrf2/HO‑1/ROS pathway.
Ma MQ, Yang C, Jin SY, Yang Y, Pan YY, Lin XH
Molecular medicine reports 2025 Jul;32(1)
Molecular medicine reports 2025 Jul;32(1)
Lutein attenuates rhabdomyolysis-induced acute kidney injury by inhibiting ACSL4-mediated ferroptosis.
Liu C, Fu Z, Zhou W, Chang X, Cui Y, Geng X, Hong Q, Lv Y, Zhou F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118222
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2025 Jul;188:118222
Apatinib combined with paclitaxel suppresses synergistically TNBC progression through enhancing ferroptosis susceptibility regulated SLC7A11/GPX4/ACSL4 axis.
Ma X, Cao D, Zhang Y, Ding X, Hu Z, Wang J
Cellular signalling 2025 Jul;131:111760
Cellular signalling 2025 Jul;131:111760
Functionalized Biomimetic Nanoparticles Targeting the IL-10/IL-10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis.
Li W, Liu Y, Wei M, Yang Z, Li Z, Guo Z, Yan L, Lu Y, Tang H, Li B, Huang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(27):e2504768
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(27):e2504768
Targeting myeloid differentiation protein 2 ameliorates rheumatoid arthritis by inhibiting inflammation and ferroptosis via MAPK and NF-κB signaling pathways.
Zhou L, Yang T, Zhang S, Liu D, Feng C, Ni J, Shi Q, Liu Y, Meng Y, Zhu Y, Tang H, Wang J, Ma A
Journal of molecular medicine (Berlin, Germany) 2025 Jul;103(7):821-836
Journal of molecular medicine (Berlin, Germany) 2025 Jul;103(7):821-836
The deubiquitinase USP24 suppresses ferroptosis in triple-negative breast cancer by stabilizing DHODH protein.
Yang L, An X, Yang S, Lin X, Chen Z, Xue Q, Chen X, Wang Y, Yan D, Chen S, Fan Y, Tang D, Yu W, Liu J, Chen X
Cell death & disease 2025 Jul 26;16(1):564
Cell death & disease 2025 Jul 26;16(1):564
Protocatechuic acid suppresses ferroptosis to protect against hypoxic-ischemic encephalopathy by targeting the HIF-1α/VEGFA axis.
Zhang X, Luo J, Bharati L, Hua Z, Chen S, Dong Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156900
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul 25;143:156900
Capsaicin Inhibits Ferroptosis through Facilitating SYVN1-Mediated Ubiquitination and Degradation of ACSL4.
Yang X, Zhang Z, Wang F, Dong X, Huang S, Ren X, Yao X, Dahms HU, Li Y, Yang J
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18437-18447
Journal of agricultural and food chemistry 2025 Jul 23;73(29):18437-18447
ILF3 promotes colorectal cancer cell resistance to ferroptosis by enhancing cysteine uptake and GSH synthesis via stabilizing SLC3A2 mRNA.
Wang S, Zhu L, Wang Y, Han Y, Wang Q, Yang W, Zhao L, Zhang Y, Pei D, Huang W, Jin A, Lin Z, Piao J
Cell death & disease 2025 Jul 23;16(1):549
Cell death & disease 2025 Jul 23;16(1):549
Metal phenolic networks-driven bufalin homodimeric prodrug nano-coassemblies for ferroptosis-augmented tumor therapy.
Wu F, Song C, Yin H, Chen R, Huang G, Zhang J, Chen H, Lin L, Yin J, Xie L, Liu W
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113814
Journal of controlled release : official journal of the Controlled Release Society 2025 Jul 10;383:113814
Microglial exosome TREM2 ameliorates ferroptosis and neuroinflammation in alzheimer's disease by activating the Wnt/β-catenin signaling.
Zhu L, Zhou T, Wu L, Zhu X, Chen L, Zhang M, Zhou J, Wang F
Scientific reports 2025 Jul 10;15(1):24968
Scientific reports 2025 Jul 10;15(1):24968
MiR-125b-5p ameliorates ventilator-induced lung injury in rats by suppressing ferroptosis via the regulation of the Keap1/Nrf2/GPX4 signaling pathway.
Zhang J, He S, Wu K, Wei Y, Li C, Zhu Q, Lian S, Wang L, Wan F, Peng F, Zhang J, Chen Z, Zhang X
Scientific reports 2025 Jul 1;15(1):21199
Scientific reports 2025 Jul 1;15(1):21199
TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4.
He Z, Zheng D, Li F, Chen L, Wu C, Zeng Z, Yu C
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jan;78:101171
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2025 Jan;78:101171
Humanin reduces nucleus pulposus cells ferroptosis to alleviate intervertebral disc degeneration: An in vitro and in vivo study.
Zhu D, Wang Z, Li Y, Chen S, Kang X
Journal of orthopaedic translation 2025 Jan;50:274-294
Journal of orthopaedic translation 2025 Jan;50:274-294
ACSL4 accelerates osteosarcoma progression via modulating TGF-β/Smad2 signaling pathway.
Li X, Chen Q, Zhao D, Tan J, Liao R, Gu Y, Zhu J, Zhang H, Xie J, Chen L
Molecular and cellular biochemistry 2025 Jan;480(1):549-562
Molecular and cellular biochemistry 2025 Jan;480(1):549-562
Quercetin inhibits hydrogen peroxide-induced cleavage of heat shock protein 90 to prevent glutathione peroxidase 4 degradation via chaperone-mediated autophagy.
Peng C, Li H, Mao Q, Tang K, Sun M, Ai Q, Yang Y, Liu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156286
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jan;136:156286
TNFα-reliant FSP1 up-regulation promotes intervertebral disc degeneration via caspase 3-dependent apoptosis.
Qiu C, Cheng L, Di D, Xiang Z, Wang C, Li J, Xiong Y, Li M, Liu J, Zhou J, Liu T, Wang X, Luo D, Wang X, Li S, Wang H, Wang X, Zhao Y, Liu X, Wang L
Genes & diseases 2025 Jan;12(1):101251
Genes & diseases 2025 Jan;12(1):101251
Melanin-Deferoxamine Nanoparticles Targeting Ferroptosis Mitigate Acute Kidney Injury via RONS Scavenging and Iron Ion Chelation.
Sun J, Shen H, Dong J, Zhang J, Yue T, Zhang R
ACS applied materials & interfaces 2025 Jan 8;17(1):282-296
ACS applied materials & interfaces 2025 Jan 8;17(1):282-296
Ethyl acetate fraction of Thesium chinense Turcz. alleviates chronic obstructive pulmonary disease through inhibition of ferroptosis mediated by activating Nrf2/SLC7A11/GPX4 axis.
Liu MJ, Xu ZP, Guan YQ, Wang YY, Wen XS, Li GH, Wang XN, Shen T
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118776
Journal of ethnopharmacology 2025 Jan 30;337(Pt 1):118776
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro.
Liu M, Xie WJ, Zhang X, Wu W, Li G, Wang L
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
Molecular medicine (Cambridge, Mass.) 2025 Jan 29;31(1):31
Dihydromyricetin ameliorates neurotoxicity induced by high glucose through restraining ferroptosis by inhibiting JNK-inflammation pathway in HT22 cells.
Peng LT, Li MW, Song ZJ, Li Q, Zhan KB, Yan CQ, Ling HY
Neuroscience 2025 Jan 26;565:40-51
Neuroscience 2025 Jan 26;565:40-51
Palmitoylation-dependent regulation of GPX4 suppresses ferroptosis.
Huang B, Wang H, Liu S, Hao M, Luo D, Zhou Y, Huang Y, Nian Y, Zhang L, Chu B, Yin C
Nature communications 2025 Jan 20;16(1):867
Nature communications 2025 Jan 20;16(1):867
Comprehensive Pan-Cancer Analysis and Functional Studies Reveal SLC2A6 as a Ferroptosis Modulator in Hepatocellular carcinoma.
Yan G, Huang H, Lu Z, Chen M, Wang X, Zhong P, Qin C, Mo S, Han C, Luo X, Ye X
Scientific reports 2025 Jan 20;15(1):2545
Scientific reports 2025 Jan 20;15(1):2545
Dose-dependent effects of hydroquinone on liver injury and lipid dysregulation based on SCD1/AMPK signaling pathway in C57BL/6 mice.
Zou L, Lin F, Wen J, Huang J, Tan Y, Huang H, Hu G
Ecotoxicology and environmental safety 2025 Jan 15;290:117724
Ecotoxicology and environmental safety 2025 Jan 15;290:117724
Selenomethionine alleviates T-2 toxin-induced articular chondrocyte ferroptosis via the system Xc(-)/GSH/GPX4 axis.
Yu FF, Zuo J, Wang M, Yu SY, Luo KT, Sha TT, Li Q, Dong ZC, Zhou GY, Zhang F, Guo X, Ba Y, Wang YJ
Ecotoxicology and environmental safety 2025 Jan 15;290:117569
Ecotoxicology and environmental safety 2025 Jan 15;290:117569
Blockade of TIPE2-Mediated Ferroptosis of Myeloid-Derived Suppressor Cells Achieves the Full Potential of Combinatory Ferroptosis and Anti-PD-L1 Cancer Immunotherapy.
Tariq HK, Liang Z, Rabiu L, Ibrahim A, Mohamady Farouk Abdalsalam N, Li R, Yang Q, Wan X, Yan D
Cells 2025 Jan 13;14(2)
Cells 2025 Jan 13;14(2)
METTL3 inhibition promotes radiosensitivity in hepatocellular carcinoma through regulation of SLC7A11 expression.
Zhang C, Yang T, Chen H, Ding X, Chen H, Liang Z, Zhao Y, Ma S, Liu X
Cell death & disease 2025 Jan 11;16(1):9
Cell death & disease 2025 Jan 11;16(1):9
A pH responsive nanocomposite for combination sonodynamic-immunotherapy with ferroptosis and calcium ion overload via SLC7A11/ACSL4/LPCAT3 pathway.
Bai X, Kang J, Wei S, Wang Y, Liu Y, Yuan B, Lu Q, Li H, Yan J, Yang X, Chang J
Exploration (Beijing, China) 2025 Feb;5(1):20240002
Exploration (Beijing, China) 2025 Feb;5(1):20240002
Activation of PAR1 contributes to ferroptosis of Schwann cells and inhibits regeneration of myelin sheath after sciatic nerve crush injury in rats via Hippo-YAP/ACSL4 pathway.
Wu Z, Sun J, Liao Z, Sun T, Huang L, Qiao J, Ling C, Chen C, Zhang B, Wang H
Experimental neurology 2025 Feb;384:115053
Experimental neurology 2025 Feb;384:115053
Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO-1 Pathways.
Huang J, Li Q, Wang H, Zhang S, Zhou X, Huang F, Chen J, Xu L, Kang D
The journal of gene medicine 2025 Feb;27(2):e70011
The journal of gene medicine 2025 Feb;27(2):e70011
Sodium pump subunit NKAα1 protects against diabetic endothelial dysfunction by inhibiting ferroptosis through the autophagy-lysosome degradation of ACSL4.
Zhu XX, Su JB, Wang FM, Chai XY, Chen G, Xu AJ, Meng XY, Qiu HB, Sun QY, Wang Y, Lv ZL, Zhang Y, Liu Y, Han ZJ, Li N, Sun HJ, Lu QB
Clinical and translational medicine 2025 Feb;15(2):e70221
Clinical and translational medicine 2025 Feb;15(2):e70221
ACSL4 promotes the formation of the proliferative subtype in hepatoblastoma.
Dang W, Li Q, Wang X
BMC cancer 2025 Feb 3;25(1):191
BMC cancer 2025 Feb 3;25(1):191
Mitophagy and immune cell interaction: insights into pathogenesis and potential targets for necrotizing enterocolitis.
Jin X, Sun W, Li Y, Zhu X
Translational pediatrics 2025 Feb 28;14(2):171-186
Translational pediatrics 2025 Feb 28;14(2):171-186
Attenuated growth factor signaling during cell death initiation sensitizes membranes towards peroxidation.
Gollowitzer A, Pein H, Rao Z, Waltl L, Bereuter L, Loeser K, Meyer T, Jafari V, Witt F, Winkler R, Su F, Große S, Thürmer M, Grander J, Hotze M, Harder S, Espada L, Magnutzki A, Gstir R, Weinigel C, Rummler S, Bonn G, Pachmayr J, Ermolaeva M, Harayama T, Schlüter H, Kosan C, Heller R, Thedieck K, Schmitt M, Shimizu T, Popp J, Shindou H, Kwiatkowski M, Koeberle A
Nature communications 2025 Feb 25;16(1):1774
Nature communications 2025 Feb 25;16(1):1774
Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice.
Liu Y, Yang G, Liu M, Zhang Y, Xu H, Mazhar M
Journal of neuroinflammation 2025 Feb 21;22(1):45
Journal of neuroinflammation 2025 Feb 21;22(1):45
Metformin Induces Apoptosis and Ferroptosis of Ovarian Cancer Cells Under Energy Stress Conditions.
Wu Y, Zhang Z, Ren M, Chen Y, Zhang J, Li J, Gao F, Bao Y, Huang Y, Yang X, Song Z
Cells 2025 Feb 2;14(3)
Cells 2025 Feb 2;14(3)
Astaxanthin Prevents Glucocorticoid-Induced Femoral Head Osteonecrosis by Targeting Ferroptosis through the JAK2/STAT3 Signaling Pathway.
Lin YZ, Chen ZH, Yang JF, Han LJ, Yu YT, Zhan JN, Tan GC, Liu LY, Xie CL, Shan P, Jin C, Liu HX
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4270-4287
Journal of agricultural and food chemistry 2025 Feb 19;73(7):4270-4287
Lactate-Fueled Theranostic Nanoplatforms for Enhanced MRI-Guided Ferroptosis Synergistic with Immunotherapy of Hepatocellular Carcinoma.
Chen X, Zhang F, Lu C, Wu R, Yang B, Liao T, Du B, Wu F, Ding J, Fang S, Zhao Z, Chen M, Shu G, Chen W, Ji J
ACS applied materials & interfaces 2025 Feb 12;17(6):9155-9172
ACS applied materials & interfaces 2025 Feb 12;17(6):9155-9172
A novel defined risk signature of ferroptosis-related lncRNAs for predicting prognosis, immune infiltration, and chemotherapy response in multiple myeloma.
Yu W, Jing Z, Tang J, Chen J
Discover oncology 2025 Feb 11;16(1):160
Discover oncology 2025 Feb 11;16(1):160
SIRT6 inhibits endoplasmic reticulum stress-mediated ferroptosis by activating Nrf2/HO-1 signaling to alleviate osteoarthritis.
Shi J, Chen L, Wang X, Ma X
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 10;74(1):35
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2025 Feb 10;74(1):35
The extract from Quzhou Aurantii Fructus attenuates cough variant asthma through inhibiting the TRPV1/Ca(2+)/NFAT/TSLP pathway and ferroptosis via TRPV1 mediation in ovalbumin-induced mice.
Tian M, Huang W, Chen J, Liu X, Wang H, Pan X, Wang L, Li Q, Gao L, Ye Y
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119038
Journal of ethnopharmacology 2025 Feb 10;338(Pt 1):119038
Coixol-Loaded Hydrogels Promote Osteochondral Defect Repair via Modulation of Ferroptosis and Autophagy in Chondrocytes.
Zhang L, Zheng G, Zhao W, He C, Huang Z
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
ACS biomaterials science & engineering 2025 Feb 10;11(2):1096-1105
Silencing of APEX1 triggers ferroptosis in clear cell renal cell carcinoma via APP-mediated activation of p53/xCT signaling.
Huang F, Ling H, Wang J
Experimental cell research 2025 Feb 1;445(1):114409
Experimental cell research 2025 Feb 1;445(1):114409
Crucial roles of asprosin in cisplatin-induced ferroptosis and acute kidney injury.
Zheng F, Lei JZ, Wang JX, Xu XY, Zhou B, Ge R, Dai M, Dong HK, Wu N, Li YH, Zhu GQ, Zhou YB
Free radical biology & medicine 2025 Feb 1;227:296-311
Free radical biology & medicine 2025 Feb 1;227:296-311
Membrane-Associated RING-CH-Type Finger 6 Protects against Hypertension-Induced Cardiac Remodeling by Suppressing Cardiomyocyte Ferroptosis Through the Degradation of ACSL4.
Hao R, Wang X, Liu C, Xue J
Inflammation 2025 Dec;48(6):4475-4491
Inflammation 2025 Dec;48(6):4475-4491
EUK nanozyme-loaded PL&GA coacervate droplets attenuate ulcerative colitis through restoring gut homeostasis and restricting intestinal cell ferroptosis.
Zhou M, Lu L, Xu X, Zhou Y, Fang H, Wang X, Li D, Li X, Hua J, Liu J, Li Y, Jiang L, Miao Q, Wen H, He J, Yang S
Materials today. Bio 2025 Dec;35:102466
Materials today. Bio 2025 Dec;35:102466
Ceria nanoparticles guard against glucocorticoid induced bone homeostasis imbalance through the promotion of osteogenesis and inhibition of osteoclastogenesis.
Zhang A, Liu Z, Zou L, Yang L, Wu Y, Wang X, Cao D, Liu J, Yang X, Zhang S
Materials today. Bio 2025 Dec;35:102308
Materials today. Bio 2025 Dec;35:102308
SIRT1 inhibits ferroptosis of granulosa cells in polycystic ovarian syndrome.
An J, Qiu Y, Guo X, Zhou Q, Li P, Zhou H, Xu C
International journal of biological macromolecules 2025 Dec;334(Pt 1):148931
International journal of biological macromolecules 2025 Dec;334(Pt 1):148931
Oridonin mitigates bacterial pneumonia by regulating mitochondrial integrity and ferroptosis via targeting KEAP1/NRF2 signaling.
Zhang W, Chen X, Zhang H, Liu X, Chen C, Lv N, Gao Y, Gao L, Shi L
Biochemical pharmacology 2025 Dec;242(Pt 2):117310
Biochemical pharmacology 2025 Dec;242(Pt 2):117310
PFGA12 ameliorates Hypoxic-Ischemic brain injury by directly regulating PRDX1 and inhibiting ferroptosis.
Chen H, Zhao J, Kang Y, Wang S, Qin D, Yu L, Zhao Y, Zhang G, Dong X
Biochemical pharmacology 2025 Dec;242(Pt 2):117307
Biochemical pharmacology 2025 Dec;242(Pt 2):117307
Time-restricted feeding protects against septic liver injury by reshaping gut microbiota and metabolite 3-hydroxybutyrate.
Hu JJ, Deng F, Sun QS, Xiong QM, Min Y, Feng SY, Lin ZB, Chen PH, Hu Z, Wu L, Chen XF, Xie S, Liu WF, Li C, Liu KX
Gut microbes 2025 Dec;17(1):2486515
Gut microbes 2025 Dec;17(1):2486515
Lycium barbarum alleviates oxidative stress-induced ferroptosis and enhances mitophagy in intervertebral disc degeneration.
Dou H, Chen Y, Chen J, Zhu Y, Yang S, Yan Y, Lin Y, Hu S
Cellular signalling 2025 Dec;136:112114
Cellular signalling 2025 Dec;136:112114
Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2-Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction.
Xu J, Wang Y, Mao W, Wei T, Li Y, Song J, Zhang C, Chen X, Chen C, Xu Q, Wu X, Song Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08725
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08725
Investigating Nickel-Induced Neurotoxicity: Associations with Gut Microbiota Dysbiosis and Ferroptosis.
Shen Y, Cao K, Zhang W, Chen C, Gao C, Wang J, Xin T, Li C, Tang S, Pei X, Li D
Antioxidants (Basel, Switzerland) 2025 Dec 9;14(12)
Antioxidants (Basel, Switzerland) 2025 Dec 9;14(12)
Nicotinamide Mononucleotide Alleviates the Development of Fibrotic Cataract by Modulating the Nrf2/FPN1 Signaling Pathway.
Bao X, Pan Y, Xu Y, Xing Y
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71348
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Dec 31;39(24):e71348
TCF3 activates super-enhancer-driven TRIB2 overexpression to suppress ferroptosis and promote hepatoblastoma proliferation.
Wu H, Zhu G, Zhu Q, Ma J, Mao S, Ding M, Zhu J, Tang X, Bian Z, Shan Y, Gu S, Sun F, Jiang C, Pan Q
Journal of experimental & clinical cancer research : CR 2025 Dec 29;44(1):329
Journal of experimental & clinical cancer research : CR 2025 Dec 29;44(1):329
GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma.
Liu X, Fang S, Ren X, Hong Y, Guo J, Liu X, Gao L, Nie H, Ning Y, Zhang M, Xu F, Liu L, Fang J, Pang Y, Zhao Q, Wang F, Wang H
Nature communications 2025 Dec 24;17(1):964
Nature communications 2025 Dec 24;17(1):964
Cold Exposure Exacerbates Allergic Airway Inflammation via Ferroptosis: Evidence from a Murine Model.
Guo X, Wang C, Yu X, Zhang S, Zheng H, Liu T, Chen Z, Wang G, Wang F
Antioxidants (Basel, Switzerland) 2025 Dec 24;15(1)
Antioxidants (Basel, Switzerland) 2025 Dec 24;15(1)
Senescence-Primed Ferroptosis Enabled by a Metal-Organic Framework Nanoplatform for Enhanced Cancer Therapy.
Yang Z, Peng Y, Zang J, Wang J, Wang Z, Zhang G, Sun J, Chen H, Xie Y, Peng X, Shan X, Wang Y, Zhang L, Li Y
ACS nano 2025 Dec 23;19(50):42689-42704
ACS nano 2025 Dec 23;19(50):42689-42704
Multi-cohort analysis and experimental study on the function of squalene epoxidase as a ferroptosis inhibitor in HCC.
Yang X, Wu Y, Zhang Q, Zhou Y, Chang S, Zhang C, Liu D
BMC cancer 2025 Dec 13;26(1):81
BMC cancer 2025 Dec 13;26(1):81
HPDA-based tubule-targeting nanoplatform alleviates oxidative stress and ferroptosis for the reversal of renal interstitial fibrosis.
Xiao Z, Luo P, Li G, Tan H, Zhou C, Zeng D, Chen Y, Li Y
Journal of nanobiotechnology 2025 Dec 13;24(1):57
Journal of nanobiotechnology 2025 Dec 13;24(1):57
Therapeutic targeting SPI1 in combination with erastin promotes ferroptosis in ccRCC.
Xue W, Wu Z, Li J, Jin P, Zhu Y, Li Z, Wang Z, Li Z, Fei X
Communications biology 2025 Dec 10;8(1):1772
Communications biology 2025 Dec 10;8(1):1772
Melanoma MHC-I-membrane-encapsulated Cu@ferrihydrite induces ferroptosis/cuproptosis and systematic immunity against tumor.
Yang R, Deng F, Gao Z, Li X, Huangfu S, Tian Q, Wang H, Liu H, Wang X, Chen Y, Yang Y, Cheng G, Zhang L
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114281
Journal of controlled release : official journal of the Controlled Release Society 2025 Dec 10;388(Pt 1):114281
Salidroside alleviates senile osteoporosis in SAMP8 mice by inhibiting the ferroptosis of bone marrow stromal cells via PI3K/AKT/mTOR signaling pathway.
Li Z, Yang S, Liu W, Ling L, Hu H, Cao Y, Xiang S
International immunopharmacology 2025 Dec 10;167:115703
International immunopharmacology 2025 Dec 10;167:115703
Baicalein attenuates metabolic dysfunction-associated steatohepatitis by regulating macrophage ferroptosis through nuclear factor (erythroid-derived 2)-like 2 pathway.
Wang Y, Zhao Y, Zhao W, Chen H, Cao Z, Li H, Tang Y, Zhu X, Yao P
Free radical biology & medicine 2025 Dec 1;240:238-252
Free radical biology & medicine 2025 Dec 1;240:238-252
Curcumin derivatives as ferroptosis inducers: design, synthesis and anti breast cancer activity evaluation.
Wu N, Zhang Y, Yin X, Du P, Piao Y, Zhao J, Zhu J, Quan Z, Wu CZ, Jin L, Zhang C
Bioorganic & medicinal chemistry 2025 Dec 1;130:118374
Bioorganic & medicinal chemistry 2025 Dec 1;130:118374
Anticancer activity of Momordica charantia-derived extracellular vesicle-like particle against cervical cancer.
Yin Q, Sun B, Qi X, Wu C, Li M, Wang B, Xu Y, Li S, Huang L, Chen B, Qi S
Tissue & cell 2025 Aug;95:102897
Tissue & cell 2025 Aug;95:102897
Glutathione peroxidase 7 knockdown inhibits growth, invasion, and migration while enhancing oxidative stress and ferroptosis in osteosarcoma cells.
He R, Xiao X, Tang X, Lv C
Journal of bone oncology 2025 Aug;53:100692
Journal of bone oncology 2025 Aug;53:100692
Lactoferrin prevents heat stroke-induced intestinal barrier damage by reducing ferroptosis via regulating MAPK signaling pathway: In vitro and in vivo studies.
Li L, Wang Y, Pei Y, Chen J, Zhou J, Gong Y, You J, Cao Y, Chen J, Cai Y, Chang W, Ma J, Ma W, Li X, Song Q, Xu S
International journal of biological macromolecules 2025 Aug;319(Pt 2):145454
International journal of biological macromolecules 2025 Aug;319(Pt 2):145454
Excessive ultra-processed foods exposure aggravates ulcerative colitis via macrophage ferroptosis.
Pang X, Yan J, Lv X, Wang J, Chen Q, Qi Y, Xu X, Wang B, Cao H
Environment international 2025 Aug;202:109706
Environment international 2025 Aug;202:109706
IGF2BP1 exacerbates neuroinflammation and cerebral ischemia/reperfusion injury by regulating neuronal ferroptosis and microglial polarization.
Li Y, Jiang J, Zhuo Y, Li J, Li Y, Xia Y, Yu Z
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167877
Biochimica et biophysica acta. Molecular basis of disease 2025 Aug;1871(6):167877
F-box only protein 10 protects against kidney tubulointerstitial fibrosis by inhibiting ACSL4-mediated lipid peroxidation and ferroptosis.
Hu J, Ma F, Chen X, Lu X, Lu Y, Jiang Y
Cellular signalling 2025 Aug;132:111841
Cellular signalling 2025 Aug;132:111841
Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3-Regulated HIF1A/HMOX1 Signaling Pathway.
Liang Z, Liu J, Gou Y, Wang H, Li Z, Cao Y, Zhang H, Bai R, Zhang Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(31):e08220
Inhibition of ferroptosis in inflammatory macrophages alleviates intestinal injury in neonatal necrotizing enterocolitis.
Shen L, Chen J, Tou J
Cell death discovery 2025 Aug 5;11(1):365
Cell death discovery 2025 Aug 5;11(1):365
Immune Characteristics of eQTL and Gene Risk Model and the Inhibitory Effect of DCTD and RRAS on Ferroptosis in Glioblastoma.
Zhang L, Chen W, Huang W, Cheng H
Frontiers in bioscience (Landmark edition) 2025 Aug 30;30(8):42844
Frontiers in bioscience (Landmark edition) 2025 Aug 30;30(8):42844
BAOXIN granules reverse ferroptosis through the solute carrier family 7 member -glutathione-glutathione peroxidase 4 axis in ischemia-induced heart failure in rats.
Xu J, Li Y, Pan F, Cao S, Wang M, Chen Y, Wang Y, Yang Y, Wu H, Huang Y, Tian J
Journal of ethnopharmacology 2025 Aug 29;352:120119
Journal of ethnopharmacology 2025 Aug 29;352:120119
GATA3 promotes ferroptosis resistance by repressing integrin β1 signaling.
Karner ER, Wang M, Goel HL, Mercurio AM
Proceedings of the National Academy of Sciences of the United States of America 2025 Aug 26;122(34):e2427304122
Proceedings of the National Academy of Sciences of the United States of America 2025 Aug 26;122(34):e2427304122
A CD147-targeted small-molecule inhibitor potentiates gemcitabine efficacy by triggering ferroptosis in pancreatic ductal adenocarcinoma.
Li J, Ma C, Cao P, Guo W, Wang P, Yang Y, Ding B, Yin F, Li Z, Wang Y, Li S, Huang C, Wang X, Zhou T, Chang A, Zhao L, Gao S, Zhao T, Wang H, Yu J, Xu J, Feng Y, Hao J
Cell reports. Medicine 2025 Aug 19;6(8):102292
Cell reports. Medicine 2025 Aug 19;6(8):102292
Qige San regulates paclitaxel resistance in esophageal cancer by targeting ferroptosis.
Song J, Guo WY, Sun LB
World journal of gastrointestinal oncology 2025 Aug 15;17(8):106783
World journal of gastrointestinal oncology 2025 Aug 15;17(8):106783
Synergistic inhibition of TNBC by USP33 and TAP63 through autophagy and ferroptosis activation.
Qu F, Jian W, Huang Y, Zhou X, Wang X, Li J, Wang G, Mainly
Cellular and molecular life sciences : CMLS 2025 Aug 13;82(1):309
Cellular and molecular life sciences : CMLS 2025 Aug 13;82(1):309
The Capability to Undergo ACSL4-Mediated Ferroptosis Is Acquired During Brown-like Adipogenesis and Affected by Hypoxia.
Mandl M, Heuboeck E, Benedikt P, Huber F, Mamunchak O, Grossmann S, Kotnik M, Hamzic-Jahic E, Bhogal CS, Lipp AM, Raml E, Zwerschke W, Wabitsch M, Voelkl J, Zierer A, Bernhard D
Cells 2025 Aug 13;14(16)
Cells 2025 Aug 13;14(16)
Resveratrol induces ferroptosis in triple-negative breast cancer through NEDD4L-mediated GPX4 ubiquitination and degradation.
Zhang E, Wang Y, Zhang H, Li X, Su Y, Cui J, Xu R, Mao X, Sang M, Lin Z, Zhou X
Free radical biology & medicine 2025 Aug 1;235:231-247
Free radical biology & medicine 2025 Aug 1;235:231-247
Role of ferroptosis mediated by abnormal membrane structure in DEHP-induced reproductive injury.
Deng W, Zhao J, Wang X, Li D, Wang M, Zheng X, Wang R, Guo Q, Zhao P, Yan H, Shen L, Long C, Wei G, Wu S
Free radical biology & medicine 2025 Aug 1;235:150-161
Free radical biology & medicine 2025 Aug 1;235:150-161
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells.
Bai G, Ke S, Lu J, Yu S, Li S, Fang M, Ling J
Journal of lipid research 2025 Apr;66(4):100776
Journal of lipid research 2025 Apr;66(4):100776
Prepubertal Exposure to Tris(2-chloroethyl) Phosphate Disrupts Blood-Testis Barrier Integrity via Ferritinophagy-Mediated Ferroptosis.
Zhao Y, Peng M, Liu H, Zhang X, Fu D
Toxics 2025 Apr 8;13(4)
Toxics 2025 Apr 8;13(4)
Impact of diabetes and metformin on cuproptosis and ferroptosis in breast cancer patients: an immunohistochemical analysis.
Li C, Chen T, Li Y, Zhou C, Du J, Li X, Tang C, Ma C, Deng N, Cui H
Discover oncology 2025 Apr 29;16(1):634
Discover oncology 2025 Apr 29;16(1):634
LncRNA FTX promotes colorectal cancer radioresistance through disturbing redox balance and inhibiting ferroptosis via miR-625-5p/SCL7A11 axis.
Dai Q, Qu TY, Yang JL, Leng J, Fang L, Zhu QQ, Wu KB, Wu J, Ma JJ, Yu HF
World journal of gastroenterology 2025 Apr 28;31(16):104305
World journal of gastroenterology 2025 Apr 28;31(16):104305
Synergistic Antioxidant and Anti-Ferroptosis Therapy via BPNS-Encapsulated Thermoresponsive Chitosan Hydrogel for Spinal Cord Injury Regeneration.
Liu Y, Wang Y, Wang X, Zeng W, Zhang Z, Zhang Z, Qi Z
Pharmaceutics 2025 Apr 26;17(5)
Pharmaceutics 2025 Apr 26;17(5)
Cytolethal distending toxin from Glaesserella parasuis induces ferroptosis in porcine alveolar macrophages and mice.
Xu S, Lei L, Yang Z, Wang Y, Du S, Zhao Q, Huang X, Cao S, Wu R, Wang Y, Yan Q, Wen Y
Veterinary research 2025 Apr 25;56(1):92
Veterinary research 2025 Apr 25;56(1):92
Mechanism and molecular targets of Euphorbia fischeriana Steud root extract in hepatocellular carcinoma.
Tian X, Liu F, Zhao J, Liu Q, Wang H, Liu Y, Zhang J, Zhang Y, Yang Y, Shi S, Jiang S
Journal of ethnopharmacology 2025 Apr 25;346:119707
Journal of ethnopharmacology 2025 Apr 25;346:119707
Bio-barrier-adaptable biomimetic nanomedicines combined with ultrasound for enhanced cancer therapy.
Guo J, Pan X, Wu Q, Li P, Wang C, Liu S, Zhang H, Huang Z, Mou X, Liu H, Xue J
Signal transduction and targeted therapy 2025 Apr 25;10(1):137
Signal transduction and targeted therapy 2025 Apr 25;10(1):137
Lactiplantibacillus plantarum -derived extracellular vesicles alleviate acute lung injury by inhibiting ferroptosis of macrophages.
Zhao Q, Lai J, Jiang Y, Cui E, Chang H, Pan R, Li P, Shao JZ, Zheng J, Chen Y
Journal of nanobiotechnology 2025 Apr 23;23(1):307
Journal of nanobiotechnology 2025 Apr 23;23(1):307
Transcription factor FOS promotes ferroptosis and inflammation in S. aureus- infected osteomyelitis via EIF5A.
Gao L, Tang Z, Zhang Z, Wei D, Wang J
Journal of orthopaedic surgery and research 2025 Apr 23;20(1):412
Journal of orthopaedic surgery and research 2025 Apr 23;20(1):412
Emodin alleviates the damage to lens epithelial cells in diabetic cataract by repressing the p53-mediated ferroptosis pathway.
Zuo X, Wang X, Xie J, Jia Y
International ophthalmology 2025 Apr 2;45(1):141
International ophthalmology 2025 Apr 2;45(1):141
Effect of Engineered Cyanobacterial Capsules on a Neurogenic Bladder after Spinal Cord Injury.
Xiao Y, He Y, Zhong D, Liu B, Tang Z, Lan X, Dong Y, Du H, Liu Y, Luo J
ACS nano 2025 Apr 1;19(12):11841-11860
ACS nano 2025 Apr 1;19(12):11841-11860
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes.
Wang W, Cheng Z, Yu M, Liu K, Duan H, Zhang Y, Huang X, Li M, Li C, Hu Y, Luo Z, Liu M
Nature communications 2025 Apr 1;16(1):3131
Nature communications 2025 Apr 1;16(1):3131
A Nutrient-Deficient Microenvironment Facilitates Ferroptosis Resistance via the FAM60A-PPAR Axis in Pancreatic Ductal Adenocarcinoma.
Pan H, Sun Y, Qian LH, Liao YN, Gai YZ, Huo YM, Li ZQ, Nie HZ
Research (Washington, D.C.) 2024;7:0300
Research (Washington, D.C.) 2024;7:0300
Atorvastatin Attenuates Endothelial Cell Injury in Atherosclerosis Through Inhibiting ACSL4-Mediated Ferroptosis.
Tan H, Liu L, Qi Y, Zhang D, Zhi Y, Li Y, Zhang H, Liu J
Cardiovascular therapeutics 2024;2024:5522013
Cardiovascular therapeutics 2024;2024:5522013
MAPK1 Mediates MAM Disruption and Mitochondrial Dysfunction in Diabetic Kidney Disease via the PACS-2-Dependent Mechanism.
Liu S, Han S, Wang C, Chen H, Xu Q, Feng S, Wang Y, Yao J, Zhou Q, Tang X, Lin L, Hu L, Davidson AJ, Yang B, Ye C, Yang F, Mao J, Tong C, Chen J, Jiang H
International journal of biological sciences 2024;20(2):569-584
International journal of biological sciences 2024;20(2):569-584
Cynaroside: a potential therapeutic agent targeting arachidonate 15-lipoxygenase to mitigate cerebral ischemia/reperfusion injury.
Cao W, Hu Y, Yu X, Long T, Sun B, Lei S, Xie P, Yu W
Frontiers in neurology 2024;15:1490640
Frontiers in neurology 2024;15:1490640
GSTT1/GSTM1 deficiency aggravated cisplatin-induced acute kidney injury via ROS-triggered ferroptosis.
Li P, Li D, Lu Y, Pan S, Cheng F, Li S, Zhang X, Huo J, Liu D, Liu Z
Frontiers in immunology 2024;15:1457230
Frontiers in immunology 2024;15:1457230
LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway.
Deng Q, Gao Y, Wang Y, Mao J, Yan Y, Yang Z, Cong Y, Yang Y, Wan S
Frontiers in pharmacology 2024;15:1411513
Frontiers in pharmacology 2024;15:1411513
Kidney tea [Orthosiphon aristatus (Blume) Miq.] improves diabetic nephropathy via regulating gut microbiota and ferroptosis.
Zhou Z, Niu H, Bian M, Zhu C
Frontiers in pharmacology 2024;15:1392123
Frontiers in pharmacology 2024;15:1392123
Surufatinib combined with photodynamic therapy induces ferroptosis to inhibit cholangiocarcinoma in vitro and in tumor models.
Huang YP, Wang YX, Zhou H, Liu ZT, Zhang ZJ, Xiong L, Zou H, Wen Y
Frontiers in pharmacology 2024;15:1288255
Frontiers in pharmacology 2024;15:1288255
Quercetin alleviates PM(2.5)-induced chronic lung injury in mice by targeting ferroptosis.
Ding S, Jiang J, Li Y
PeerJ 2024;12:e16703
PeerJ 2024;12:e16703
The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation.
Kang Z, Fu Z, Tian X, Geng Y, Zhang Q, Liu Y, Wang X, Luo H, Yang Z
Frontiers in public health 2024;12:1496439
Frontiers in public health 2024;12:1496439
Urolithin A alleviates cell senescence by inhibiting ferroptosis and enhances corneal epithelial wound healing.
Guo XX, Chang XJ, Pu Q, Li AL, Li J, Li XY
Frontiers in medicine 2024;11:1441196
Frontiers in medicine 2024;11:1441196
ACSL4 upregulates IFI44 and IFI44L expression and promotes the proliferation and invasiveness of head and neck squamous cell carcinoma cells.
Rupa D, Chuang HW, Hu CE, Su WM, Wu SR, Lee HS, Yuan TC
Cancer science 2024 Sep;115(9):3026-3040
Cancer science 2024 Sep;115(9):3026-3040
Reactive Oxygen Species-Scavenging Mesoporous Poly(tannic acid) Nanospheres Alleviate Acute Kidney Injury by Inhibiting Ferroptosis.
Qin J, Li Z, Feng Y, Guo Y, Zhao Z, Sun S, Zheng J, Zhang M, Zhang J, Zhang Y, Wei J, Ding C, Xue W
ACS biomaterials science & engineering 2024 Sep 9;10(9):5856-5868
ACS biomaterials science & engineering 2024 Sep 9;10(9):5856-5868
METTL16-SENP3-LTF axis confers ferroptosis resistance and facilitates tumorigenesis in hepatocellular carcinoma.
Wang J, Xiu M, Wang J, Gao Y, Li Y
Journal of hematology & oncology 2024 Sep 2;17(1):78
Journal of hematology & oncology 2024 Sep 2;17(1):78
Phosphatase LHPP confers prostate cancer ferroptosis activation by modulating the AKT-SKP2-ACSL4 pathway.
Xie G, Li N, Li K, Xu Y, Zhang Y, Cao S, Huang B, Liu R, Zhou P, Ding Y, Ding Y, Yang J, Jia Z, Huang Z
Cell death & disease 2024 Sep 11;15(9):665
Cell death & disease 2024 Sep 11;15(9):665
Histamine deficiency exacerbates cisplatin-induced ferroptosis in cochlea hair cells of HDC knockout mice.
Wu D, Zhu B, Yang X, Sun D, Zhu J, Jiang K, Shen N, Yang X, Huang X
International immunopharmacology 2024 Sep 10;138:112639
International immunopharmacology 2024 Sep 10;138:112639
Unveiling the role of RhoA and ferroptosis in vascular permeability: Implications for osteoarthritis.
He X, Tian K, Lin X, Chen X, Su Y, Lu Z, Chen Z, Zhang L, Li P, Ma L, Feng G, Zhao X, Lan Z, Zhang C, Xue D, Jin Q
International journal of molecular medicine 2024 Oct;54(4)
International journal of molecular medicine 2024 Oct;54(4)
Golgi protein ACBD3 downregulation sensitizes cells to ferroptosis.
Qian Y, Ma S, Qiu R, Sun Z, Liu W, Wu F, Lam SM, Xia Z, Wang K, Fang L, Shui G, Cao X
Cell biology international 2024 Oct;48(10):1559-1572
Cell biology international 2024 Oct;48(10):1559-1572
FTO alleviated ferroptosis in septic cardiomyopathy via mediating the m6A modification of BACH1.
Zeng H, Xu J, Wu R, Wang X, Jiang Y, Wang Q, Guo J, Xiao F
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167307
A respiratory Streptococcus strain inhibits Acinetobacter baumannii from causing inflammatory damage through ferroptosis.
Sun Y, Li S, Che Y, Liang H, Guo Y, Xiao C
BMC microbiology 2024 Oct 28;24(1):437
BMC microbiology 2024 Oct 28;24(1):437
Human breast milk-derived phospholipid DOPE ameliorates intestinal injury associated with NEC by inhibiting ferroptosis.
Chen Y, Chen W, Dai Y, Yan X, Jiang C, Zhang F, Zhang M, Hu X, Zhao J, Wu T, Li S, Han S, Chen X
Food & function 2024 Oct 28;15(21):10811-10822
Food & function 2024 Oct 28;15(21):10811-10822
Overexpression of miR-451a Aggravates Renal Ischemia-Reperfusion Injury by Targeting KLF1-ACSL4 to Promote Ferroptosis.
Yu H, Gou X
Current issues in molecular biology 2024 Oct 23;46(11):11853-11867
Current issues in molecular biology 2024 Oct 23;46(11):11853-11867
Lysosomal iron accumulation and subsequent lysosomes-mitochondria iron transmission mediate PFOS-induced hepatocyte ferroptosis.
Li J, Feng R, Yang W, Liang P, Qiu T, Zhang J, Sun X, Li Q, Yang G, Yao X
Ecotoxicology and environmental safety 2024 Oct 1;284:116890
Ecotoxicology and environmental safety 2024 Oct 1;284:116890
Emerging perfluoroalkyl substances retard skeletal growth by accelerating osteoblasts senescence via ferroptosis.
Wang X, Wang K, Mao W, Fan Z, Liu T, Hong R, Chen H, Pan C
Environmental research 2024 Oct 1;258:119483
Environmental research 2024 Oct 1;258:119483
Contribution of impaired autophagy, mitochondrial dysfunction and abnormal lipolysis to epididymal aging in mice.
Liu C, Wu C, Zhang S, Lv Z
Experimental gerontology 2024 Oct 1;195:112528
Experimental gerontology 2024 Oct 1;195:112528
Unveiling the crucial role of ferroptosis in host resistance to streptococcus agalactiae infection.
Yi JX, Sun ZY, Liu P, Wang YH, Liu H, Lv QY, Kong DC, Huang WH, Ren YH, Li Q, Jiang YQ, Li J, Jiang H
Cell death discovery 2024 Oct 1;10(1):423
Cell death discovery 2024 Oct 1;10(1):423
Sodium citrate targeting Ca(2+)/CAMKK2 pathway exhibits anti-tumor activity through inducing apoptosis and ferroptosis in ovarian cancer.
Wu Y, Jia C, Liu W, Zhan W, Chen Y, Lu J, Bao Y, Wang S, Yu C, Zheng L, Sun L, Song Z
Journal of advanced research 2024 Nov;65:89-104
Journal of advanced research 2024 Nov;65:89-104
Manganese drives ferroptosis of cancer cells via YAP/TAZ phase separation activated ACSL4 in OSCC.
Chen H, Cui H, Liu W, Li BW, Tian Z, Zhao YY, Yu GT
Oral diseases 2024 Nov;30(8):4898-4908
Oral diseases 2024 Nov;30(8):4898-4908
Intra-articular injection of platinum nanozyme-loaded silk fibroin/pullulan hydrogels relieves osteoarthritis through ROS scavenging and ferroptosis suppression.
Feng J, Deng X, Hao P, Zhu Z, Li T, Yuan X, Hu J, Wang Y
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
International journal of biological macromolecules 2024 Nov;280(Pt 2):135863
Astrocyte-derived lactoferrin inhibits neuronal ferroptosis by reducing iron content and GPX4 degradation in APP/PS1 transgenic mice.
Fan YG, Ge RL, Ren H, Jia RJ, Wu TY, Lei XF, Wu Z, Zhou XB, Wang ZY
Pharmacological research 2024 Nov;209:107404
Pharmacological research 2024 Nov;209:107404
Lithospermic acid improves liver fibrosis through Piezo1-mediated oxidative stress and inflammation.
Luo S, Yang B, Xu H, Pan X, Chen X, Jue X, Liu S, Wan R, Tan Q, Yao Y, Chen X, Jiang J, Deng B, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155974
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Nov;134:155974
IL6 Derived from Macrophages under Intermittent Hypoxia Exacerbates NAFLD by Promoting Ferroptosis via MARCH3-Led Ubiquitylation of GPX4.
Cai W, Wu S, Ming X, Li Z, Pan D, Yang X, Yang M, Yuan Y, Chen X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2402241
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Nov;11(41):e2402241
Development of oxidative stress- and ferroptosis-related prognostic signature in gastric cancer and identification of CDH19 as a novel biomarker.
Wang S, Zhang S, Li X, Leng C, Li X, Lv J, Zhao S, Qiu W, Guo J
Human genomics 2024 Nov 5;18(1):121
Human genomics 2024 Nov 5;18(1):121
Iberverin Downregulates GPX4 and SLC7A11 to Induce Ferroptotic Cell Death in Hepatocellular Carcinoma Cells.
Yang H, Dai B, Chen L, Li Y, Jin X, Gao C, Han L, Bian X
Biomolecules 2024 Nov 5;14(11)
Biomolecules 2024 Nov 5;14(11)
TIMP1 regulates ferroptosis in osteoblasts by inhibiting TFRC ubiquitination: an in vitro and in vivo study.
Peng B, Feng Z, Yang A, Liu J, He J, Xu L, Tian C, Sheng X, Wang Y, Chen R, Wang X, Ren X, Geng B, Xia Y
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):226
Molecular medicine (Cambridge, Mass.) 2024 Nov 23;30(1):226
Melatonin Attenuates Ferritinophagy/Ferroptosis by Acting on Autophagy in the Liver of an Autistic Mouse Model BTBR T(+)Itpr3(tf)/J.
Cominelli G, Lonati C, Pinto D, Rinaldi F, Franco C, Favero G, Rezzani R
International journal of molecular sciences 2024 Nov 23;25(23)
International journal of molecular sciences 2024 Nov 23;25(23)
Carthamin yellow alleviates dextran sodium sulfate-induced ulcerative colitis by repairing the intestinal barrier and activating the Nrf2/GPX4 axis.
Bian W, Wei L, Wang K
International immunopharmacology 2024 Nov 15;141:113020
International immunopharmacology 2024 Nov 15;141:113020
LncRNA MALAT1 promotes Erastin-induced ferroptosis in the HBV-infected diffuse large B-cell lymphoma.
Bai X, Li J, Guo X, Huang Y, Xu X, Tan A, Jia Y, Sun Q, Guo X, Chen J, Kang J
Cell death & disease 2024 Nov 12;15(11):819
Cell death & disease 2024 Nov 12;15(11):819
Treatment of Parkinson's disease model with human umbilical cord mesenchymal stem cell-derived exosomes loaded with BDNF.
Wang CC, Hu XM, Long YF, Huang HR, He Y, Xu ZR, Qi ZQ
Life sciences 2024 Nov 1;356:123014
Life sciences 2024 Nov 1;356:123014
The effect of tau K677 lactylation on ferritinophagy and ferroptosis in Alzheimer's disease.
An X, He J, Xie P, Li C, Xia M, Guo D, Bi B, Wu G, Xu J, Yu W, Ren Z
Free radical biology & medicine 2024 Nov 1;224:685-706
Free radical biology & medicine 2024 Nov 1;224:685-706
Epithelial Piezo1 deletion ameliorates intestinal barrier damage by regulating ferroptosis in ulcerative colitis.
Zhu J, Wu Y, Zhang L, Bai B, Han W, Wang H, Mei Q
Free radical biology & medicine 2024 Nov 1;224:272-286
Free radical biology & medicine 2024 Nov 1;224:272-286
Hippocampal Pyk2 regulates specific social skills: Implications for schizophrenia.
López-Molina L, Sancho-Balsells A, Al-Massadi O, Montalban E, Alberch J, Arranz B, Girault JA, Giralt A
Neurobiology of disease 2024 May;194:106487
Neurobiology of disease 2024 May;194:106487
A combined nanotherapeutic approach targeting farnesoid X receptor, ferroptosis, and fibrosis for nonalcoholic steatohepatitis treatment.
Fu J, Zhang P, Sun Z, Lu G, Cao Q, Chen Y, Wu W, Zhang J, Zhuang C, Sheng C, Xu J, Lu Y, Wang P
Acta pharmaceutica Sinica. B 2024 May;14(5):2228-2246
Acta pharmaceutica Sinica. B 2024 May;14(5):2228-2246
Development and Application of the CRISPR-dcas13d-eIF4G Translational Regulatory System to Inhibit Ferroptosis in Calcium Oxalate Crystal-Induced Kidney Injury.
He Z, Song C, Li S, Dong C, Liao W, Xiong Y, Yang S, Liu Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 May;11(17):e2309234
FTH1 overexpression using a dCasRx translation enhancement system protects the kidney from calcium oxalate crystal-induced injury.
He Z, Dong C, Song T, Zhou J, Xu T, He R, Li S
Cellular & molecular biology letters 2024 May 7;29(1):65
Cellular & molecular biology letters 2024 May 7;29(1):65
MiR-31-5p alleviates septic cardiomyopathy by targeting BAP1 to inhibit SLC7A11 deubiquitination and ferroptosis.
Liu Y, Hu N, Ai B, Xia H, Li W
BMC cardiovascular disorders 2024 May 30;24(1):286
BMC cardiovascular disorders 2024 May 30;24(1):286
Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis-mediated MUFA synthesis.
Yuan Y, Xu J, Jiang Q, Yang C, Wang N, Liu X, Piao HL, Lu S, Zhang X, Han L, Liu Z, Cai J, Liu F, Chen S, Liu J
Journal of experimental & clinical cancer research : CR 2024 May 3;43(1):133
Journal of experimental & clinical cancer research : CR 2024 May 3;43(1):133
ABI3BP promotes renal aging through Klotho-mediated ferroptosis.
Ji R, Wei L, Zan Y, Li X, Ma S, Ma L, He X, Wang L, Ding Y
Journal of translational medicine 2024 May 29;22(1):514
Journal of translational medicine 2024 May 29;22(1):514
[Inhibition of Lung Squamous Cancer Target HMGCS1 Promotes Cellular Ferroptosis].
Ni Y, Yang Y, Zhang L
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2024 May 20;27(5):330-336
Zhongguo fei ai za zhi = Chinese journal of lung cancer 2024 May 20;27(5):330-336
Metabolomics analysis revealed the neuroprotective role of 2-phosphoglyceric acid in hypoxic-ischemic brain damage through GPX4/ACSL4 axis regulation.
Chen H, Wusiman Y, Zhao J, Zhang W, Liu W, Wang S, Qian G, Zhang G, Le M, Dong X
European journal of pharmacology 2024 May 15;971:176539
European journal of pharmacology 2024 May 15;971:176539
Evaluating the efficacy and mechanisms of Hua-Zhuo-Ning-Fu-Decoction on psoriasis using integrated bioinformatics analysis and metabolomics.
Man S, Ma W, Jiang H, Haider A, Shi S, Li X, Wu Z, Song Y
Journal of ethnopharmacology 2024 May 10;325:117856
Journal of ethnopharmacology 2024 May 10;325:117856
Kinase PIM1 governs ferroptosis to reduce retinal microvascular endothelial cell dysfunction triggered by high glucose.
Xie HB, Guo JH, Yang MM, Wang JT
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
In vitro cellular & developmental biology. Animal 2024 Mar;60(3):278-286
Therapeutic potential and mechanisms of Rifaximin in ameliorating iron overload-induced ferroptosis and liver fibrosis in vivo and in vitro.
Yuan Q, Fang Y, Guo J, Zhang Z, Liao J, Kuang J
Toxicology and applied pharmacology 2024 Mar;484:116845
Toxicology and applied pharmacology 2024 Mar;484:116845
Allogeneic platelet-rich plasma inhibits ferroptosis in promoting wound repair of type 2 diabetic ulcers.
Zhou D, Liang Q, Ge X, Xu J
Free radical biology & medicine 2024 Mar;215:37-47
Free radical biology & medicine 2024 Mar;215:37-47
Propionate promotes ferroptosis and apoptosis through mitophagy and ACSL4-mediated ferroptosis elicits anti-leukemia immunity.
Wei Y, Liu W, Wang R, Chen Y, Liu J, Guo X, Can C, Yang X, Wang D, Hu X, Ma D
Free radical biology & medicine 2024 Mar;213:36-51
Free radical biology & medicine 2024 Mar;213:36-51
Enhanced glutathione production protects against zearalenone-induced oxidative stress and ferroptosis in female reproductive system.
Fu W, Dai C, Ma Z, Li Q, Lan D, Sun C, Wu X, Li J, Wang S
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2024 Mar;185:114462
DTTZ suppresses ferroptosis and reverses mitochondrial dysfunction in normal tissues affected by chemotherapy.
Yang Y, Chen Y, Tang H, Zhang Z, Zhou X, Xu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Mar;172:116227
Ozone-mediated cerebral protection: Unraveling the mechanism through ferroptosis and the NRF2/SLC7A11/GPX4 signaling pathway.
Zhu F, Ding S, Liu Y, Wang X, Wu Z
Journal of chemical neuroanatomy 2024 Mar;136:102387
Journal of chemical neuroanatomy 2024 Mar;136:102387
NRF2 activation ameliorates blood-brain barrier injury after cerebral ischemic stroke by regulating ferroptosis and inflammation.
Fan W, Chen H, Li M, Fan X, Jiang F, Xu C, Wang Y, Wei W, Song J, Zhong D, Li G
Scientific reports 2024 Mar 4;14(1):5300
Scientific reports 2024 Mar 4;14(1):5300
Piezo1 channel exaggerates ferroptosis of nucleus pulposus cells by mediating mechanical stress-induced iron influx.
Xiang Z, Zhang P, Jia C, Xu R, Cao D, Xu Z, Lu T, Liu J, Wang X, Qiu C, Fu W, Li W, Cheng L, Yang Q, Feng S, Wang L, Zhao Y, Liu X
Bone research 2024 Mar 29;12(1):20
Bone research 2024 Mar 29;12(1):20
Cancer associated fibroblast secreted miR-432-5p targets CHAC1 to inhibit ferroptosis and promote acquired chemoresistance in prostate cancer.
Zhao J, Shen J, Mao L, Yang T, Liu J, Hongbin S
Oncogene 2024 Jun;43(27):2104-2114
Oncogene 2024 Jun;43(27):2104-2114
The TF/Nrf2/GSTP1 pathway is involved in stress-induced hepatocellular injury through ferroptosis.
Tian X, Li Y, Lei L, Feng X, Xin H, Chen H, Zhang G, Zuo M, Shi W, Cong B
Journal of cellular and molecular medicine 2024 Jun;28(12):e18494
Journal of cellular and molecular medicine 2024 Jun;28(12):e18494
ACSL4 promotes malignant progression of Hepatocellular carcinoma by targeting PAK2 transcription.
Wu D, Zuo Z, Sun X, Li X, Yin F, Yin W
Biochemical pharmacology 2024 Jun;224:116206
Biochemical pharmacology 2024 Jun;224:116206
Experimental verification about treatment of Bu-Shen-Yi-Jing-Fang in Alzheimer's disease by the analysis of the feasible signaling pathway of network pharmacology.
Hu Y, Hao R, Li D, Lu Y, Yu G
BMC complementary medicine and therapies 2024 Jun 8;24(1):222
BMC complementary medicine and therapies 2024 Jun 8;24(1):222
Phosphorylated FOXQ1, a novel substrate of JNK1, inhibits sorafenib-induced ferroptosis by activating ETHE1 in hepatocellular carcinoma.
Liu Y, Shao K, Yang W, Shen Q, Lu M, Shao Z, Chu S, Wang Y, Wang X, Chen X, Bai J, Wu X
Cell death & disease 2024 Jun 5;15(6):395
Cell death & disease 2024 Jun 5;15(6):395
MARK4 aggravates cardiac dysfunction in mice with STZ-induced diabetic cardiomyopathy by regulating ACSL4-mediated myocardial lipid metabolism.
Wu Y, Zhang J, Wang W, Wu D, Kang Y, Fu L
Scientific reports 2024 Jun 5;14(1):12978
Scientific reports 2024 Jun 5;14(1):12978
Isorhamnetin alleviates ferroptosis-mediated colitis by activating the NRF2/HO-1 pathway and chelating iron.
Ru Y, Luo Y, Liu D, Huang Q, Zhou X, Linghu M, Luo X, Lv Z, Wu Y, Zhang H, Huang Y
International immunopharmacology 2024 Jun 30;135:112318
International immunopharmacology 2024 Jun 30;135:112318
Ciprofloxacin is a novel anti-ferroptotic antibiotic.
Chen F, Tang H, Lin J, Kang R, Tang D, Liu J
Heliyon 2024 Jun 15;10(11):e32571
Heliyon 2024 Jun 15;10(11):e32571
Metabolomics reveals that ferroptosis participates in bisphenol A-induced testicular injury.
Chi LK, Yuan Q, Wang MY, Guo CR, Zhu XD, Jiang HB, Zhang QH, Zhao Y, Li L, Yan H
Heliyon 2024 Jun 15;10(11):e31667
Heliyon 2024 Jun 15;10(11):e31667
ACLS4 could be a potential therapeutic target for severe acute pancreatitis.
Guo F, Lu Y, Du L, Guo X, Xie J, Cai X
Scientific reports 2024 Jun 12;14(1):13457
Scientific reports 2024 Jun 12;14(1):13457
ERRFI1 exacerbates hepatic ischemia reperfusion injury by promoting hepatocyte apoptosis and ferroptosis in a GRB2-dependent manner.
Zhao H, Mao H
Molecular medicine (Cambridge, Mass.) 2024 Jun 11;30(1):82
Molecular medicine (Cambridge, Mass.) 2024 Jun 11;30(1):82
Lipoxin A(4) ameliorates knee osteoarthritis progression in rats by antagonizing ferroptosis through activation of the ESR2/LPAR3/Nrf2 axis in synovial fibroblast-like synoviocytes.
Hu Z, Chen L, Zhao J, Zhang W, Jin Z, Sun Y, Li Z, Chang B, Shen P, Yang Y
Redox biology 2024 Jul;73:103143
Redox biology 2024 Jul;73:103143
DDX39B protects against sorafenib-induced ferroptosis by facilitating the splicing and cytoplasmic export of GPX4 pre-mRNA in hepatocellular carcinoma.
Li Q, Yuan H, Zhao G, Ou D, Zhang J, Li L, Li S, Feng T, Gu R, Kou Q, Wang Q, Li S, Wang G, Zhao M, Yu H, Qu J, Lin P, Li K
Biochemical pharmacology 2024 Jul;225:116251
Biochemical pharmacology 2024 Jul;225:116251
TaoHe ChengQi decoction ameliorates sepsis-induced cardiac dysfunction through anti-ferroptosis via the Nrf2 pathway.
Lu SM, Yang B, Tan ZB, Wang HJ, Xie JD, Xie MT, Jiang WH, Huang JZ, Li J, Zhang L, Tan YZ, Zhang JZ, Liu B, Wu WW, Zhang SW
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155597
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155597
Intermittent hypoxia exacerbates metabolic dysfunction-associated fatty liver disease by aggravating hepatic copper deficiency-induced ferroptosis.
Wang R, Lv Y, Ni Z, Feng W, Fan P, Wang Y, Lin Y, Chen X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23788
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jul 15;38(13):e23788
Ferroptosis: First evidence in premature duck ovary induced by polyvinyl chloride microplastics.
Ali W, Chen Y, Shah MG, Buriro RS, Sun J, Liu Z, Zou H
The Science of the total environment 2024 Jul 10;933:173032
The Science of the total environment 2024 Jul 10;933:173032
KLF6 silencing attenuates MCAO-induced brain injury and cognitive dysfunction via targeting ferroptosis and activating the Nrf2/HO-1 pathway.
Qian H, Zhou S, Qian R, Li Q, Zhang J, Ding Y, Wang C
Human & experimental toxicology 2024 Jan-Dec;43:9603271241304372
Human & experimental toxicology 2024 Jan-Dec;43:9603271241304372
Cadmium Induces Kidney Iron Deficiency and Chronic Kidney Injury by Interfering with the Iron Metabolism in Rats.
Zhang K, Long M, Dong W, Li J, Wang X, Liu W, Huang Q, Ping Y, Zou H, Song R, Liu G, Ran D, Liu Z
International journal of molecular sciences 2024 Jan 7;25(2)
International journal of molecular sciences 2024 Jan 7;25(2)
Inhibition of cisplatin-induced Acsl4-mediated ferroptosis alleviated ovarian injury.
Wang S, Li X, Li J, Wang A, Li F, Hu H, Long T, Pei X, Li H, Zhong F, Zhu F
Chemico-biological interactions 2024 Jan 5;387:110825
Chemico-biological interactions 2024 Jan 5;387:110825
FGF10 protects against LPS-induced epithelial barrier injury and inflammation by inhibiting SIRT1-ferroptosis pathway in acute lung injury in mice.
Lin L, Yang L, Wang N, Chen S, Du X, Chen R, Zhang H, Kong X
International immunopharmacology 2024 Jan 25;127:111426
International immunopharmacology 2024 Jan 25;127:111426
Selenium-SelK-GPX4 axis protects nucleus pulposus cells against mechanical overloading-induced ferroptosis and attenuates senescence of intervertebral disc.
Jia C, Xiang Z, Zhang P, Liu L, Zhu X, Yu R, Liu Z, Wang S, Liu K, Wang Z, Vasilev K, Zhou S, Geng Z, Liu X, Zhao Y, Gao Y, Cheng L, Li Y
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Cellular and molecular life sciences : CMLS 2024 Jan 22;81(1):49
Heliox Protects SH-SY5Y Cells from Oxygen-Glucose Deprivation/Reperfusion-Induced Ferroptosis.
Yu S, Xiong W, Xu W, Chen Y
Journal of integrative neuroscience 2024 Jan 16;23(1):14
Journal of integrative neuroscience 2024 Jan 16;23(1):14
Quercetin attenuates cerebral ischemic injury by inhibiting ferroptosis via Nrf2/HO-1 signaling pathway.
Peng C, Ai Q, Zhao F, Li H, Sun Y, Tang K, Yang Y, Chen N, Liu F
European journal of pharmacology 2024 Jan 15;963:176264
European journal of pharmacology 2024 Jan 15;963:176264
Resveratrol protected against the development of endometriosis by promoting ferroptosis through miR-21-3p/p53/SLC7A11 signaling pathway.
Zou W, Wang X, Xia X, Zhang T, Nie M, Xiong J, Fang X
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Biochemical and biophysical research communications 2024 Jan 15;692:149338
Transient receptor potential channel TRPM4 favors oxidized low-density lipoprotein-induced coronary endothelial cell dysfunction via a mechanism involving ferroptosis.
Ye F, Liu D, Zhang J
Tissue & cell 2024 Feb;86:102290
Tissue & cell 2024 Feb;86:102290
7-Dehydrocholesterol dictates ferroptosis sensitivity.
Li Y, Ran Q, Duan Q, Jin J, Wang Y, Yu L, Wang C, Zhu Z, Chen X, Weng L, Li Z, Wang J, Wu Q, Wang H, Tian H, Song S, Shan Z, Zhai Q, Qin H, Chen S, Fang L, Yin H, Zhou H, Jiang X, Wang P
Nature 2024 Feb;626(7998):411-418
Nature 2024 Feb;626(7998):411-418
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Xu X, Mao Y, Feng Z, Dai F, Gu T, Zheng J
Oncology reports 2024 Feb;51(2)
Oncology reports 2024 Feb;51(2)
Se-(Methyl)-selenocysteine ameliorates blood-brain barrier disruption of focal cerebral ischemia mice via ferroptosis inhibition and tight junction upregulation in an Akt/GSK3β-dependent manner.
Fei Y, Li T, Wu R, Xu X, Hu S, Yang Y, Jin C, Tang W, Zhang X, Du Q, Liu C
Psychopharmacology 2024 Feb;241(2):379-399
Psychopharmacology 2024 Feb;241(2):379-399
Interactome Analysis Identifies the Role of BZW2 in Promoting Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Metabolism.
Maio G, Smith M, Bhawal R, Zhang S, Baskin JM, Li J, Lin H
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100709
Molecular & cellular proteomics : MCP 2024 Feb;23(2):100709
WWP2 protects against sepsis-induced cardiac injury through inhibiting cardiomyocyte ferroptosis.
Li Z, Wu B, Chen J, Ye N, Ma R, Song C, Sun Y, Zhang X, Sun G
Journal of translational internal medicine 2024 Feb;12(1):35-50
Journal of translational internal medicine 2024 Feb;12(1):35-50
4-amino-2-trifluoromethyl-phenyl retinate alleviates lipopolysaccharide-induced acute myocardial injury through activation of the KLF4/p62 axis.
Dan Z, Shi X, Shu C, Zhu R, Wang Y, Zhu H
Cellular signalling 2024 Feb;114:111001
Cellular signalling 2024 Feb;114:111001
Verteporfin induces lipid peroxidation and ferroptosis in pancreatic cancer cells.
Zhou W, Lim A, Elmadbouh OHM, Edderkaoui M, Osipov A, Mathison AJ, Urrutia R, Liu T, Wang Q, Pandol SJ
Free radical biology & medicine 2024 Feb 20;212:493-504
Free radical biology & medicine 2024 Feb 20;212:493-504
Sensitization of cancer cells to ferroptosis coincident with cell cycle arrest.
Rodencal J, Kim N, He A, Li VL, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Long JZ, Sage J, Dixon SJ
Cell chemical biology 2024 Feb 15;31(2):234-248.e13
Cell chemical biology 2024 Feb 15;31(2):234-248.e13
High expression of TBRG4 in relation to unfavorable outcome and cell ferroptosis in hepatocellular carcinoma.
Tao S, Cui D, Cheng H, Liu X, Jiang Z, Chen H, Gao Y
BMC cancer 2024 Feb 12;24(1):194
BMC cancer 2024 Feb 12;24(1):194
PRKN-mediated the ubiquitination of IQGAP3 regulates cell growth, metastasis and ferroptosis in early-onset colorectal cancer.
Chen G, Cong L, Gu C, Li P
Journal of bioenergetics and biomembranes 2024 Dec;56(6):645-655
Journal of bioenergetics and biomembranes 2024 Dec;56(6):645-655
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor-suppressing effects on diffuse large B-cell lymphoma (DLBCL) by inducing ferroptosis through the regulation of the NRF2/SLC7A11/GPX4 pathway.
Zhang J, Wang T, Zhang H, Li N, Liu B, Fang L
Toxicology and applied pharmacology 2024 Dec;493:117148
Toxicology and applied pharmacology 2024 Dec;493:117148
The m(6)A modification of ACSL4 mRNA sensitized esophageal squamous cell carcinoma to irradiation via accelerating ferroptosis.
Jin Y, Pan S, Wang M, Huang S, Ke Y, Li D, Luo H, Kou Z, Shi D, Kou W, Fu H, Pan J
Cell biology international 2024 Dec;48(12):1877-1890
Cell biology international 2024 Dec;48(12):1877-1890
Sirt6 overexpression relieves ferroptosis and delays the progression of diabetic nephropathy via Nrf2/GPX4 pathway.
Du L, Guo C, Zeng S, Yu K, Liu M, Li Y
Renal failure 2024 Dec;46(2):2377785
Renal failure 2024 Dec;46(2):2377785
Mild therapeutic hypothermic protection activates the PI3K/AKT signaling pathway to inhibit TRPM7 and suppress ferroptosis induced by myocardial ischemia‑reperfusion injury.
Li Y, Chen Y, Yu P, Zhang D, Tang X, Zhu Z, Xiao F, Deng W, Liu Y, Tan Z, Zhang J, Yu S
Molecular medicine reports 2024 Dec;30(6)
Molecular medicine reports 2024 Dec;30(6)
Comprehensive Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Data Unveils Sevoflurane-Induced Neurotoxicity Through SLC7A11-Associated Ferroptosis.
Hu X, Zhang Y, Guo L, Xiao R, Yuan L, Liu F
Journal of cellular and molecular medicine 2024 Dec;28(24):e70307
Journal of cellular and molecular medicine 2024 Dec;28(24):e70307
Naringenin alleviates intestinal ischemia/reperfusion injury by inhibiting ferroptosis via targeting YAP/STAT3 signaling axis.
Hou M, Li X, Chen F, Tan Z, Han X, Liu J, Zhou J, Shi Y, Zhang J, Lv J, Leng Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156095
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Dec;135:156095
Self-Produced O(2) CNs-Based Nanocarriers of DNA Hydrophobization Strategy Triggers Photodynamic and Mitochondrial-Derived Ferroptosis for Hepatocellular Carcinoma Combined Treatment.
Liu MX, Liu YC, Cai YT, Gu YY, Zhu YQ, Zhang N, Zhu WZ, Liu YH, Yu L, Zhang QT, Zhang XL
Advanced healthcare materials 2024 Dec;13(31):e2402110
Advanced healthcare materials 2024 Dec;13(31):e2402110
Sirtuin1 Suppresses Calcium Oxalate Nephropathy via Inhibition of Renal Proximal Tubular Cell Ferroptosis Through PGC-1α-mediated Transcriptional Coactivation.
Duan C, Li B, Liu H, Zhang Y, Yao X, Liu K, Wu X, Mao X, Wu H, Xu Z, Zhong Y, Hu Z, Gong Y, Xu H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408945
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Dec;11(48):e2408945
Conjugated fatty acids drive ferroptosis through chaperone-mediated autophagic degradation of GPX4 by targeting mitochondria.
Hirata Y, Yamada Y, Taguchi S, Kojima R, Masumoto H, Kimura S, Niijima T, Toyama T, Kise R, Sato E, Uchida Y, Ito J, Nakagawa K, Taguchi T, Inoue A, Saito Y, Noguchi T, Matsuzawa A
Cell death & disease 2024 Dec 6;15(12):884
Cell death & disease 2024 Dec 6;15(12):884
BMAL1 alleviates sepsis-induced AKI by inhibiting ferroptosis.
Yang S, Ye Z, Chen W, Wang P, Zhao S, Zhou X, Li W, Cheng F
International immunopharmacology 2024 Dec 5;142(Pt B):113159
International immunopharmacology 2024 Dec 5;142(Pt B):113159
MCM4 potentiates evasion of hepatocellular carcinoma from sorafenib-induced ferroptosis through Nrf2 signaling pathway.
Liu X, Zhang F, Fan Y, Qiu C, Wang K
International immunopharmacology 2024 Dec 5;142(Pt A):113107
International immunopharmacology 2024 Dec 5;142(Pt A):113107
Screening of orthopedic medicines identifies raloxifene hydrochloride as a novel ferroptosis inhibitor for spinal cord injury therapy.
Su S, Wu X, Zhu Y, Yang S, Lu K, Zhang X, Zhang D, Wang X
International immunopharmacology 2024 Dec 25;143(Pt 3):113542
International immunopharmacology 2024 Dec 25;143(Pt 3):113542
Ruscogenin attenuates osteoarthritis by modulating oxidative stress-mediated macrophage reprogramming via directly targeting Sirt3.
Liu Y, Li W, Tang H, Yang Z, Wei M, Zhou W, Li Z, Huang W
International immunopharmacology 2024 Dec 25;143(Pt 1):113336
International immunopharmacology 2024 Dec 25;143(Pt 1):113336
ASIC1a regulates ferroptosis in hepatic stellate cells via the Hippo/Yap-1 pathway in liver fibrosis.
Zhu Y, Cao C, Li Z, Xu Z, Qian S, Zhang J, Li M, Hu X, Zhang A, Du N, Pan X, Wang X, Sun Y, Wang J, Huang Y
International immunopharmacology 2024 Dec 25;143(Pt 1):113226
International immunopharmacology 2024 Dec 25;143(Pt 1):113226
ACSL4-mediated ZIP7-VDAC3 interaction regulates endoplasmic reticulum-mitochondria iron transfer in hepatocytes under PFOS exposure.
Liang P, Tian K, Yang W, Feng R, Li Y, Hu L, Wang K, Qiu T, Zhang J, Sun X, Yao X
The Science of the total environment 2024 Dec 20;957:177679
The Science of the total environment 2024 Dec 20;957:177679
Chemerin attenuates acute kidney injury by inhibiting ferroptosis via the AMPK/NRF2/SLC7A11 axis.
Ma Y, Fei S, Chen X, Gui Y, Zhou B, Xiang T, Liu J, Yue K, Li Q, Jiang W, Sun C, Huang X
Communications biology 2024 Dec 19;7(1):1679
Communications biology 2024 Dec 19;7(1):1679
Integrated network pharmacology and transcriptomics to explore the mechanism of compound Dihuang granule (CDG) protects dopaminergic neurons by regulating the Nrf2/HMOX1 pathway in the 6-OHDA/MPP(+)-induced model of Parkinson's disease.
Sun X, Yang S, He Z, Wang L, He J
Chinese medicine 2024 Dec 18;19(1):170
Chinese medicine 2024 Dec 18;19(1):170
High glucose elevates intracellular calcium level and induces ferroptosis in glomerular endothelial cells through the miR-223-3p/ITPR3 pathway.
Wang D, Zhang L, Nan J, Wan S, Luo J, Li X, Chen W
Molecular and cellular endocrinology 2024 Dec 1;594:112384
Molecular and cellular endocrinology 2024 Dec 1;594:112384
Ion channel Piezo1 induces ferroptosis of trabecular meshwork cells: a novel observation in the pathogenesis in primary open angle glaucoma.
Liu K, Xu J, Yang R, Wang F, Su Y
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1591-C1603
American journal of physiology. Cell physiology 2024 Dec 1;327(6):C1591-C1603
A polo-like kinase 1 inhibitor enhances erastin sensitivity in head and neck squamous cell carcinoma cells in vitro.
Wu X, Wu J
Cancer chemotherapy and pharmacology 2024 Aug;94(2):183-195
Cancer chemotherapy and pharmacology 2024 Aug;94(2):183-195
Propofol Mitigates Sepsis-Induced Brain Injury by Inhibiting Ferroptosis Via Activation of the Nrf2/HO-1axis.
Zhou Y, Yang Y, Yi L, Pan M, Tang W, Duan H
Neurochemical research 2024 Aug;49(8):2131-2147
Neurochemical research 2024 Aug;49(8):2131-2147
GOLPH3 inhibits erastin-induced ferroptosis in colorectal cancer cells.
Chen L, Wang C, Chen X, Wu Y, Chen M, Deng X, Qiu C
Cell biology international 2024 Aug;48(8):1198-1211
Cell biology international 2024 Aug;48(8):1198-1211
Preventive effects of lactoferrin on acute alcohol-induced liver injury via iron chelation and regulation of iron metabolism.
Guan S, Zhang S, Liu M, Guo J, Chen Y, Shen X, Deng X, Lu J
Journal of dairy science 2024 Aug;107(8):5316-5329
Journal of dairy science 2024 Aug;107(8):5316-5329
Identification of ferroptosis-related key genes associated with immune infiltration in sepsis by bioinformatics analysis and in vivo validation.
Shi R, Bai C, Sun S, Wang F, Li C, Wang C, Hu L, Zhao Z, Guo Q, Du G, Xu D, Chen AF, Yang W
Gene 2024 Aug 5;918:148482
Gene 2024 Aug 5;918:148482
Sterigmatocystin declines mouse oocyte quality by inducing ferroptosis and asymmetric division defects.
Wang S, Wu X, Yang J, Peng Y, Miao F, Li M, Zeng J
Journal of ovarian research 2024 Aug 28;17(1):175
Journal of ovarian research 2024 Aug 28;17(1):175
APOL6 predicts immunotherapy efficacy of bladder cancer by ferroptosis.
Fan Z, Liu Y, Wang X, Xu Y, Huang R, Shi W, Qu Y, Ruan J, Zhou C, Zhao X, Liu L
BMC cancer 2024 Aug 26;24(1):1046
BMC cancer 2024 Aug 26;24(1):1046
Screening of NSAIDs library identifies Tinoridine as a novel ferroptosis inhibitor for potential intervertebral disc degeneration therapy.
Yang S, Zhu Y, Shi Y, Su S, Liang H, Li S, Wu Z, Miao J, Chen Y, Zhang X, Wang X
Free radical biology & medicine 2024 Aug 20;221:245-256
Free radical biology & medicine 2024 Aug 20;221:245-256
Natural Product Auraptene Targets SLC7A11 for Degradation and Induces Hepatocellular Carcinoma Ferroptosis.
Li D, Li Y, Chen L, Gao C, Dai B, Yu W, Yang H, Pi J, Bian X
Antioxidants (Basel, Switzerland) 2024 Aug 20;13(8)
Antioxidants (Basel, Switzerland) 2024 Aug 20;13(8)
Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis.
Huang Q, Yang J, Zhang J, Yao L, Jiang B, Du S, Li F, Peng Q, Qin L, Wang Y, Qi L
iScience 2024 Aug 16;27(8):110496
iScience 2024 Aug 16;27(8):110496
Tetramethylpyrazine alleviates ferroptosis and promotes functional recovery in spinal cord injury by regulating GPX4/ACSL4.
Liu G, Deng B, Huo L, Fan X, Bai H, Zhao Y, Xu L, Gao F, Mu X
European journal of pharmacology 2024 Aug 15;977:176710
European journal of pharmacology 2024 Aug 15;977:176710
Autophagy-mediated ferroptosis is involved in development of severe acute pancreatitis.
Li H, Wu D, Zhang H, Liu S, Zhen J, Yan Y, Li P
BMC gastroenterology 2024 Aug 1;24(1):245
BMC gastroenterology 2024 Aug 1;24(1):245
Sodium octanoate alleviates cardiac and cerebral injury after traumatic cardiac arrest in a porcine model.
Lin Y, Chen Q, Zhang G, Xie L, Yang X, Zhong H, Xu J, Zhang M
The American journal of emergency medicine 2024 Apr;78:48-56
The American journal of emergency medicine 2024 Apr;78:48-56
FTO ameliorates doxorubicin-induced cardiotoxicity by inhibiting ferroptosis via P53-P21/Nrf2 activation in a HuR-dependent m6A manner.
Yang Y, Ren J, Zhang J, Shi H, Wang J, Yan Y
Redox biology 2024 Apr;70:103067
Redox biology 2024 Apr;70:103067
Magnolin alleviated DSS-induced colitis by inhibiting ALOX5-mediated ferroptosis.
Yao T, Yao YY, Wang JZ, Jiang SM, Li LJ
The Kaohsiung journal of medical sciences 2024 Apr;40(4):360-373
The Kaohsiung journal of medical sciences 2024 Apr;40(4):360-373
GPX4-mediated bone ferroptosis under mechanical stress decreased bone formation via the YAP-TEAD signalling pathway.
Mengjia W, Jun J, Xin Z, Jiahao Z, Jie G
Journal of cellular and molecular medicine 2024 Apr;28(7):e18231
Journal of cellular and molecular medicine 2024 Apr;28(7):e18231
Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1.
Wright T, Turnis ME, Grace CR, Li X, Brakefield LA, Wang YD, Xu H, Kaminska E, Climer LK, Mukiza TO, Chang CL, Moldoveanu T, Opferman JT
Molecular cell 2024 Apr 4;84(7):1338-1353.e8
Molecular cell 2024 Apr 4;84(7):1338-1353.e8
Non-targeted metabolomics strategy reveals the role of Geng-Nian-Shu in regulating ferroptosis in perimenopausal syndrome.
Lv X, Bi A, Zhang Z, Li J, Wei Y, Wan M, Wang J, Yan T, Jia Y
Journal of pharmaceutical and biomedical analysis 2024 Apr 15;241:115980
Journal of pharmaceutical and biomedical analysis 2024 Apr 15;241:115980
CHAC1 exacerbates LPS-induced ferroptosis and apoptosis in HK-2 cells by promoting oxidative stress.
Zhou Z, Zhang H
Allergologia et immunopathologia 2023;51(2):99-110
Allergologia et immunopathologia 2023;51(2):99-110
Detection of Ferroptosis by Immunohistochemistry and Immunofluorescence.
Zhong X, Chen R
Methods in molecular biology (Clifton, N.J.) 2023;2712:211-222
Methods in molecular biology (Clifton, N.J.) 2023;2712:211-222
Phosphatidylethanolamine aggravates Angiotensin II-induced atrial fibrosis by triggering ferroptosis in mice.
Huang F, Liu X, Liu J, Xie Y, Zhao L, Liu D, Zeng Z, Liu X, Zheng S, Xiao Z
Frontiers in pharmacology 2023;14:1148410
Frontiers in pharmacology 2023;14:1148410
Yttrium chloride induces ferroptosis in cardiomyocytes via iron accumulation and triggers cardiac lipid peroxidation and inflammation that cause heart adverse events in mice.
Xiong L, Huang J, Wu C, Yuan Q, Wang S, Zhu L, Li Z, Sun Z, Fang Y, Li W, Hu G
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Ecotoxicology and environmental safety 2023 Sep 15;263:115279
Matrine Alleviates Sepsis-Induced Myocardial Injury by Inhibiting Ferroptosis and Apoptosis.
Xiao Y, Yu Y, Hu L, Yang Y, Yuan Y, Zhang W, Luo J, Yu L
Inflammation 2023 Oct;46(5):1684-1696
Inflammation 2023 Oct;46(5):1684-1696
TRAP1 inhibits MARCH5-mediated MIC60 degradation to alleviate mitochondrial dysfunction and apoptosis of cardiomyocytes under diabetic conditions.
Zhang L, Luo Y, Lv L, Chen S, Liu G, Zhao T
Cell death and differentiation 2023 Oct;30(10):2336-2350
Cell death and differentiation 2023 Oct;30(10):2336-2350
URI alleviates tyrosine kinase inhibitors-induced ferroptosis by reprogramming lipid metabolism in p53 wild-type liver cancers.
Ding Z, Pan Y, Shang T, Jiang T, Lin Y, Yang C, Pang S, Cui X, Wang Y, Feng XF, Xu M, Pei M, Chen Y, Li X, Ding J, Tan Y, Wang H, Dong L, Wang L
Nature communications 2023 Oct 7;14(1):6269
Nature communications 2023 Oct 7;14(1):6269
STING/ACSL4 axis-dependent ferroptosis and inflammation promote hypertension-associated chronic kidney disease.
Gao L, Zhang J, Yang T, Jiang L, Liu X, Wang S, Wang X, Huang Y, Wang H, Zhang M, Gong T, Ma L, Li C, He C, Meng XM, Wu Y
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3084-3103
Molecular therapy : the journal of the American Society of Gene Therapy 2023 Oct 4;31(10):3084-3103
Insight into the effect of a heavy metal mixture on neurological damage in rats through combined serum metabolomic and brain proteomic analyses.
Xie J, Zhou F, Ouyang L, Li Q, Rao S, Su R, Yang S, Li J, Wan X, Yan L, Liu P, Cheng H, Li L, Du G, Feng C, Fan G
The Science of the total environment 2023 Oct 15;895:165009
The Science of the total environment 2023 Oct 15;895:165009
Macrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis.
Wu Q, Liang Z, Jiang J, Feng X, Liu J, Zhang Z, Wang H, Wang N, Gou Y, Li Z, Cao Y
Cell death & disease 2023 Oct 11;14(10):668
Cell death & disease 2023 Oct 11;14(10):668
GCH1 reduces LPS-induced alveolar macrophage polarization and inflammation by inhibition of ferroptosis.
Xiao Y, Yuan Y, Yang Y, Liu B, Ding Z, Luo J, Chen S, Yu L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Nov;72(10-11):1941-1955
E3 ubiquitin ligase Siah1 aggravates NAFLD through Scp2 ubiquitination.
Zhu Z, Hu X, Liu K, Li J, Fan K, Wang H, Wang L, He L, Ma Y, Guan R, Wang Z
International immunopharmacology 2023 Nov;124(Pt A):110897
International immunopharmacology 2023 Nov;124(Pt A):110897
The BRD4-SRPK2-SRSF2 signal modulates the splicing efficiency of ACSL3 pre-mRNA and influences erastin-induced ferroptosis in osteosarcoma cells.
Luo SH, Tian JM, Chu Y, Zhu HY, Ni JD, Huang J
Cell death & disease 2023 Nov 23;14(11):760
Cell death & disease 2023 Nov 23;14(11):760
PDPN(+) CAFs facilitate the motility of OSCC cells by inhibiting ferroptosis via transferring exosomal lncRNA FTX.
Li Y, Ma Z, Li W, Xu X, Shen P, Zhang SE, Cheng B, Xia J
Cell death & disease 2023 Nov 22;14(11):759
Cell death & disease 2023 Nov 22;14(11):759
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Ding S, Jiang J, Zhang G, Yu M, Zheng Y
Ecotoxicology and environmental safety 2023 May;256:114897
Ecotoxicology and environmental safety 2023 May;256:114897
Germacrone protects renal tubular cells against ferroptotic death and ROS release by re-activating mitophagy in diabetic nephropathy.
Wang Y, He X, Xue M, Sun W, He Q, Jin J
Free radical research 2023 May-Jun;57(6-12):413-429
Free radical research 2023 May-Jun;57(6-12):413-429
ACSL4 serves as a novel prognostic biomarker correlated with immune infiltration in Cholangiocarcinoma.
Liu S, Fan S, Wang Y, Chen R, Wang Z, Zhang Y, Jiang W, Chen Y, Xu X, Yu Y, Li C, Li X
BMC cancer 2023 May 16;23(1):444
BMC cancer 2023 May 16;23(1):444
Non-canonical function of DPP4 promotes cognitive impairment through ERp29-associated mitochondrial calcium overload in diabetes.
Li J, Hui Y, Xu Z, Tan J, Yin K, Kuang L, Tang Y, Wei J, Zhong Q, Zheng T
iScience 2023 Mar 17;26(3):106271
iScience 2023 Mar 17;26(3):106271
ZNF8-miR-552-5p Axis Modulates ACSL4-Mediated Ferroptosis in Hepatocellular Carcinoma.
Yang H, Sun W, Bi T, Sun J, Lu Z, Li J, Wei H
DNA and cell biology 2023 Jun;42(6):336-347
DNA and cell biology 2023 Jun;42(6):336-347
1,25-Dihydroxyvitamin D3 alleviates hyperandrogen-induced ferroptosis in KGN cells.
Jiang Y, Yang J, Du K, Luo K, Yuan X, Hua F
Hormones (Athens, Greece) 2023 Jun;22(2):273-280
Hormones (Athens, Greece) 2023 Jun;22(2):273-280
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes.
Yang Y, Fu X, Xia B, Zhou L, Zhang H, Li C, Ye X, Liu T
Heliyon 2023 Jul;9(7):e17891
Heliyon 2023 Jul;9(7):e17891
Curcumin preconditioning enhances the neuroprotective effects of olfactory mucosa-derived mesenchymal stem cells on experimental intracerebral hemorrhage.
Huang Y, Liu J, He J, Tan F, Lu M, Yuan F, Zhu X, Kong L
Heliyon 2023 Jul;9(7):e17874
Heliyon 2023 Jul;9(7):e17874
Dihydroorotate dehydrogenase regulates ferroptosis in neurons after spinal cord injury via the P53-ALOX15 signaling pathway.
Li D, Lu X, Xu G, Liu S, Gong Z, Lu F, Xia X, Jiang J, Wang H, Zou F, Ma X
CNS neuroscience & therapeutics 2023 Jul;29(7):1923-1939
CNS neuroscience & therapeutics 2023 Jul;29(7):1923-1939
SCP2 mediates the transport of lipid hydroperoxides to mitochondria in chondrocyte ferroptosis.
Dai T, Xue X, Huang J, Yang Z, Xu P, Wang M, Xu W, Feng Z, Zhu W, Xu Y, Chen J, Li S, Meng Q
Cell death discovery 2023 Jul 8;9(1):234
Cell death discovery 2023 Jul 8;9(1):234
Long non-coding RNA PVT1 regulates atherosclerosis progression via the microRNA-106b-5p/ACSL4 axis.
Zhang M, Yu Z, Zhao L, Luo H
Biochemical and biophysical research communications 2023 Jul 30;667:170-179
Biochemical and biophysical research communications 2023 Jul 30;667:170-179
A Cell Cycle-Dependent Ferroptosis Sensitivity Switch Governed by EMP2.
Rodencal J, Kim N, Li VL, He A, Lange M, He J, Tarangelo A, Schafer ZT, Olzmann JA, Sage J, Long JZ, Dixon SJ
bioRxiv : the preprint server for biology 2023 Jul 19;
bioRxiv : the preprint server for biology 2023 Jul 19;
Protective effect of total flavonoids of Engelhardia roxburghiana Wall. leaves against radiation-induced intestinal injury in mice and its mechanism.
Wu S, Tian C, Tu Z, Guo J, Xu F, Qin W, Chang H, Wang Z, Hu T, Sun X, Ning H, Li Y, Gou W, Hou W
Journal of ethnopharmacology 2023 Jul 15;311:116428
Journal of ethnopharmacology 2023 Jul 15;311:116428
Protective effects of brain and muscle ARNT-like gene 1 on oxidized low-density lipoprotein-induced human brain microvascular endothelial cell injury by alleviating ferroptosis.
Yu S, Zeng Y, Ruan C, Bai L, Liang Z
Human & experimental toxicology 2023 Jan-Dec;42:9603271231184630
Human & experimental toxicology 2023 Jan-Dec;42:9603271231184630
SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.
Cheng L, He Q, Liu B, Chen L, Lv F, Li X, Li Y, Liu C, Song Y, Xing Y
Cell death & disease 2023 Jan 31;14(1):74
Cell death & disease 2023 Jan 31;14(1):74
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition.
Ganji R, Paulo JA, Xi Y, Kline I, Zhu J, Clemen CS, Weihl CC, Purdy JG, Gygi SP, Raman M
Nature communications 2023 Feb 6;14(1):638
Nature communications 2023 Feb 6;14(1):638
3,6-Epidioxy-1,10-bisaboladiene induces ferroptosis-like cell death through lipid peroxidation.
Usukhbayar N, Takano Y, Uesugi S, Muroi M, Osada H, Kimura KI
Free radical research 2023 Dec;57(3):208-222
Free radical research 2023 Dec;57(3):208-222
Xanthohumol attenuates renal ischemia/reperfusion injury by inhibiting ferroptosis.
Tang Z, Feng Y, Nie W, Li C
Experimental and therapeutic medicine 2023 Dec;26(6):571
Experimental and therapeutic medicine 2023 Dec;26(6):571
Inhibition of CARM1-Mediated Methylation of ACSL4 Promotes Ferroptosis in Colorectal Cancer.
Feng S, Rao Z, Zhang J, She X, Chen Y, Wan K, Li H, Zhao C, Feng Y, Wang G, Hu J, Luo X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303484
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(36):e2303484
Characteristics and time points to inhibit ferroptosis in human osteoarthritis.
Xu Y, Yang Z, Dai T, Xue X, Xia D, Feng Z, Huang J, Chen X, Sun S, Zhou J, Dai Y, Zong J, Li S, Meng Q
Scientific reports 2023 Dec 7;13(1):21592
Scientific reports 2023 Dec 7;13(1):21592
lnc-HC ameliorates steatosis by promoting miR-130b-3p biogenesis and the assembly of an RNA-induced silencing complex.
Lan X, Ren J, Du X, Zhang L, Wang S, Yang X, Lu S
Molecular and cellular endocrinology 2023 Dec 1;578:112061
Molecular and cellular endocrinology 2023 Dec 1;578:112061
Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer.
Peng P, Ren Y, Wan F, Tan M, Wu H, Shen J, Qian C, Liu X, Xiang Y, Yu Q, Zhang L, Si Y, Liu Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154921
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154921
PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis.
Xue X, Dai T, Chen J, Xu Y, Yang Z, Huang J, Xu W, Li S, Meng Q
Journal of orthopaedic surgery and research 2023 Aug 24;18(1):620
Journal of orthopaedic surgery and research 2023 Aug 24;18(1):620
Pterostilbene ameliorates oxidative damage and ferroptosis in human ovarian granulosa cells by regulating the Nrf2/HO-1 pathway.
Chen X, Song QL, Li ZH, Ji R, Wang JY, Cao ML, Mu XF, Zhang Y, Guo DY, Yang J
Archives of biochemistry and biophysics 2023 Apr;738:109561
Archives of biochemistry and biophysics 2023 Apr;738:109561
Mitochondria-localized cGAS suppresses ferroptosis to promote cancer progression.
Qiu S, Zhong X, Meng X, Li S, Qian X, Lu H, Cai J, Zhang Y, Wang M, Ye Z, Zhang H, Gao P
Cell research 2023 Apr;33(4):299-311
Cell research 2023 Apr;33(4):299-311
Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
Dong C, Song C, He Z, Song Q, Song T, Liu J, Xiong Y, Su X, Zhou J, Yang S, Liao W
International immunopharmacology 2023 Apr;117:110042
International immunopharmacology 2023 Apr;117:110042
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer.
Chen C, Yang Y, Guo Y, He J, Chen Z, Qiu S, Zhang Y, Ding H, Pan J, Pan Y
Cell death & disease 2023 Apr 14;14(4):271
Cell death & disease 2023 Apr 14;14(4):271
Cyclosporine A-loaded apoferritin alleviates myocardial ischemia-reperfusion injury by simultaneously blocking ferroptosis and apoptosis of cardiomyocytes.
Qian W, Liu D, Han Y, Liu M, Liu B, Ji Q, Zhang B, Mei Q, Zhou S, Cheng Y
Acta biomaterialia 2023 Apr 1;160:265-280
Acta biomaterialia 2023 Apr 1;160:265-280
The Effects of Alda-1 Treatment on Renal and Intestinal Injuries After Cardiopulmonary Resuscitation in Pigs.
Yu Q, Gao J, Shao X, Lu W, Chen L, Jin L
Frontiers in medicine 2022;9:892472
Frontiers in medicine 2022;9:892472
Activation of SIRT1 Alleviates Ferroptosis in the Early Brain Injury after Subarachnoid Hemorrhage.
Yuan B, Zhao XD, Shen JD, Chen SJ, Huang HY, Zhou XM, Han YL, Zhou LJ, Lu XJ, Wu Q
Oxidative medicine and cellular longevity 2022;2022:9069825
Oxidative medicine and cellular longevity 2022;2022:9069825
Atorvastatin Inhibits Ferroptosis of H9C2 Cells by regulatingSMAD7/Hepcidin Expression to Improve Ischemia-Reperfusion Injury.
Peng Y, Liao B, Zhou Y, Zeng W, Zeng ZY
Cardiology research and practice 2022;2022:3972829
Cardiology research and practice 2022;2022:3972829
Zinc Oxide Nanoparticle Inhibits Tumorigenesis of Renal Cell Carcinoma by Modulating Lipid Metabolism Targeting miR-454-3p to Repressing Metabolism Enzyme ACSL4.
Zhou X, Cao T
Journal of oncology 2022;2022:2883404
Journal of oncology 2022;2022:2883404
Probiotic Saccharomyces boulardii attenuates cardiopulmonary bypass-induced acute lung injury by inhibiting ferroptosis.
Li J, Gao PF, Xu YX, Gu H, Wang QX
American journal of translational research 2022;14(7):5003-5013
American journal of translational research 2022;14(7):5003-5013
Itraconazole Inhibits the Growth of Cutaneous Squamous Cell Carcinoma by Targeting HMGCS1/ACSL4 Axis.
Xu C, Zhuo Y, Liu Y, Chen H
Frontiers in pharmacology 2022;13:828983
Frontiers in pharmacology 2022;13:828983
NAT10: An RNA cytidine transferase regulates fatty acid metabolism in cancer cells.
Dalhat MH, Mohammed MRS, Alkhatabi HA, Rehan M, Ahmad A, Choudhry H, Khan MI
Clinical and translational medicine 2022 Sep;12(9):e1045
Clinical and translational medicine 2022 Sep;12(9):e1045
Context-dependent regulation of ferroptosis sensitivity.
Magtanong L, Mueller GD, Williams KJ, Billmann M, Chan K, Armenta DA, Pope LE, Moffat J, Boone C, Myers CL, Olzmann JA, Bensinger SJ, Dixon SJ
Cell chemical biology 2022 Sep 15;29(9):1409-1418.e6
Cell chemical biology 2022 Sep 15;29(9):1409-1418.e6
Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells.
Zhao Y, Zhang R, Wang Z, Chen Z, Wang G, Guan S, Lu J
Journal of agricultural and food chemistry 2022 Oct 12;70(40):12953-12967
Journal of agricultural and food chemistry 2022 Oct 12;70(40):12953-12967
α-Syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson's disease.
A A, W C, N N, L M, M D, Zhang DD
Free radical biology & medicine 2022 Nov 1;192:130-140
Free radical biology & medicine 2022 Nov 1;192:130-140
Amentoflavone promotes ferroptosis by regulating reactive oxygen species (ROS) /5'AMP-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR) to inhibit the malignant progression of endometrial carcinoma cells.
Sun Q, Zhen P, Li D, Liu X, Ding X, Liu H
Bioengineered 2022 May;13(5):13269-13279
Bioengineered 2022 May;13(5):13269-13279
Plasma-activated medium induces ferroptosis by depleting FSP1 in human lung cancer cells.
Jo A, Bae JH, Yoon YJ, Chung TH, Lee EW, Kim YH, Joh HM, Chung JW
Cell death & disease 2022 Mar 7;13(3):212
Cell death & disease 2022 Mar 7;13(3):212
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy.
Liu C, Sun W, Zhu T, Shi S, Zhang J, Wang J, Gao F, Ou Q, Jin C, Li J, Xu JY, Zhang J, Tian H, Xu GT, Lu L
Redox biology 2022 Jun;52:102292
Redox biology 2022 Jun;52:102292
Puerarin Attenuates Oxidative Stress and Ferroptosis via AMPK/PGC1α/Nrf2 Pathway after Subarachnoid Hemorrhage in Rats.
Huang Y, Wu H, Hu Y, Zhou C, Wu J, Wu Y, Wang H, Lenahan C, Huang L, Nie S, Gao X, Sun J
Antioxidants (Basel, Switzerland) 2022 Jun 27;11(7)
Antioxidants (Basel, Switzerland) 2022 Jun 27;11(7)
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
Inhibition of the PIN1-NRF2/GPX4 axis imparts sensitivity to cisplatin in cervical cancer cells.
Zhang Z, Hu Q, Ye S, Xiang L
Acta biochimica et biophysica Sinica 2022 Aug 25;54(9):1325-1335
Acta biochimica et biophysica Sinica 2022 Aug 25;54(9):1325-1335
Phyto-sesquiterpene lactones DET and DETD-35 induce ferroptosis in vemurafenib sensitive and resistant melanoma via GPX4 inhibition and metabolic reprogramming.
Chang MT, Tsai LC, Nakagawa-Goto K, Lee KH, Shyur LF
Pharmacological research 2022 Apr;178:106148
Pharmacological research 2022 Apr;178:106148
Ferroptosis is involved in PGPS-induced otitis media in C57BL/6 mice.
Yan B, Xie D, Wu Y, Wang S, Zhang X, Zhao T, Liu L, Ma P, Li G, Yang Y, Zhao Y, Zheng T, Geng R, Li B, Zheng Q
Cell death discovery 2022 Apr 21;8(1):217
Cell death discovery 2022 Apr 21;8(1):217
Reduced ER-mitochondria connectivity promotes neuroblastoma multidrug resistance.
Çoku J, Booth DM, Skoda J, Pedrotty MC, Vogel J, Liu K, Vu A, Carpenter EL, Ye JC, Chen MA, Dunbar P, Scadden E, Yun TD, Nakamaru-Ogiso E, Area-Gomez E, Li Y, Goldsmith KC, Reynolds CP, Hajnoczky G, Hogarty MD
The EMBO journal 2022 Apr 19;41(8):e108272
The EMBO journal 2022 Apr 19;41(8):e108272
Silencing of lncRNA MALAT1 facilitates erastin-induced ferroptosis in endometriosis through miR-145-5p/MUC1 signaling.
Liang Z, Wu Q, Wang H, Tan J, Wang H, Gou Y, Cao Y, Li Z, Zhang Z
Cell death discovery 2022 Apr 11;8(1):190
Cell death discovery 2022 Apr 11;8(1):190
The Ferroptosis-NLRP1 Inflammasome: The Vicious Cycle of an Adverse Pregnancy.
Meihe L, Shan G, Minchao K, Xiaoling W, Peng A, Xili W, Jin Z, Huimin D
Frontiers in cell and developmental biology 2021;9:707959
Frontiers in cell and developmental biology 2021;9:707959
Oxalate Activates Autophagy to Induce Ferroptosis of Renal Tubular Epithelial Cells and Participates in the Formation of Kidney Stones.
Song Q, Liao W, Chen X, He Z, Li D, Li B, Liu J, Liu L, Xiong Y, Song C, Yang S
Oxidative medicine and cellular longevity 2021;2021:6630343
Oxidative medicine and cellular longevity 2021;2021:6630343
Stearoyl-CoA Desaturase 1 Potentiates Hypoxic plus Nutrient-Deprived Pancreatic Cancer Cell Ferroptosis Resistance.
Gao J, Zhang Z, Liu Y, Zhang Z, Wang M, Gong A, Xia L, Liao X, Wang D, Zhu H
Oxidative medicine and cellular longevity 2021;2021:6629804
Oxidative medicine and cellular longevity 2021;2021:6629804
Mesenchymal Stem Cells Alleviate Post-resuscitation Cardiac and Cerebral Injuries by Inhibiting Cell Pyroptosis and Ferroptosis in a Swine Model of Cardiac Arrest.
Xu J, Zhang M, Liu F, Shi L, Jiang X, Chen C, Wang J, Diao M, Khan ZU, Zhang M
Frontiers in pharmacology 2021;12:793829
Frontiers in pharmacology 2021;12:793829
Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer.
Li XX, Xiong L, Wen Y, Zhang ZJ
Frontiers in genetics 2021;12:774400
Frontiers in genetics 2021;12:774400
Non-enzymatic lipid peroxidation initiated by photodynamic therapy drives a distinct ferroptosis-like cell death pathway.
Shui S, Zhao Z, Wang H, Conrad M, Liu G
Redox biology 2021 Sep;45:102056
Redox biology 2021 Sep;45:102056
LncRNA OIP5-AS1 inhibits ferroptosis in prostate cancer with long-term cadmium exposure through miR-128-3p/SLC7A11 signaling.
Zhang Y, Guo S, Wang S, Li X, Hou D, Li H, Wang L, Xu Y, Ma B, Wang H, Jiang X
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ecotoxicology and environmental safety 2021 Sep 1;220:112376
Ferrostatin-1 alleviated TNBS induced colitis via the inhibition of ferroptosis.
Xu J, Liu S, Cui Z, Wang X, Ning T, Wang T, Zhang N, Xie S, Min L, Zhang S, Liang C, Zhu S
Biochemical and biophysical research communications 2021 Oct 8;573:48-54
Biochemical and biophysical research communications 2021 Oct 8;573:48-54
High-fat diet impairs ferroptosis and promotes cancer invasiveness via downregulating tumor suppressor ACSL4 in lung adenocarcinoma.
Zhang Y, Li S, Li F, Lv C, Yang QK
Biology direct 2021 May 31;16(1):10
Biology direct 2021 May 31;16(1):10
Nuclear receptor coactivator 4-mediated ferritinophagy drives proliferation of dental pulp stem cells in hypoxia.
Yang A, Wang L, Jiang K, Lei L, Li H
Biochemical and biophysical research communications 2021 May 21;554:123-130
Biochemical and biophysical research communications 2021 May 21;554:123-130
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites.
Chai P, Cheng Y, Hou C, Yin L, Zhang D, Hu Y, Chen Q, Zheng P, Teng J, Chen J
The Journal of cell biology 2021 Jul 5;220(7)
The Journal of cell biology 2021 Jul 5;220(7)
Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62-Keap1-Nrf2 Pathway.
Zhao Y, Lu J, Mao A, Zhang R, Guan S
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
Journal of agricultural and food chemistry 2021 Aug 25;69(33):9671-9683
A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets.
Watanabe M, Saeki Y, Takahashi H, Ohtake F, Yoshida Y, Kasuga Y, Kondo T, Yaguchi H, Suzuki M, Ishida H, Tanaka K, Hatakeyama S
Communications biology 2020 Oct 20;3(1):592
Communications biology 2020 Oct 20;3(1):592
LncRNA NEAT1 promotes docetaxel resistance in prostate cancer by regulating ACSL4 via sponging miR-34a-5p and miR-204-5p.
Jiang X, Guo S, Zhang Y, Zhao Y, Li X, Jia Y, Xu Y, Ma B
Cellular signalling 2020 Jan;65:109422
Cellular signalling 2020 Jan;65:109422
Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases.
Ndiaye H, Liu JY, Hall A, Minogue S, Morgan MY, Waugh MG
Bioscience reports 2020 Apr 30;40(4)
Bioscience reports 2020 Apr 30;40(4)
The oncometabolite 2-hydroxyglutarate produced by mutant IDH1 sensitizes cells to ferroptosis.
Wang TX, Liang JY, Zhang C, Xiong Y, Guan KL, Yuan HX
Cell death & disease 2019 Oct 7;10(10):755
Cell death & disease 2019 Oct 7;10(10):755
Integrated Metabolomics and Lipidomics Analyses Reveal Metabolic Reprogramming in Human Glioma with IDH1 Mutation.
Zhou L, Wang Z, Hu C, Zhang C, Kovatcheva-Datchary P, Yu D, Liu S, Ren F, Wang X, Li Y, Hou X, Piao H, Lu X, Zhang Y, Xu G
Journal of proteome research 2019 Mar 1;18(3):960-969
Journal of proteome research 2019 Mar 1;18(3):960-969
The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells.
Radif Y, Ndiaye H, Kalantzi V, Jacobs R, Hall A, Minogue S, Waugh MG
Molecular and cellular biochemistry 2018 Nov;448(1-2):275-286
Molecular and cellular biochemistry 2018 Nov;448(1-2):275-286
Quantitative proteomics by SWATH-MS reveals sophisticated metabolic reprogramming in hepatocellular carcinoma tissues.
Gao Y, Wang X, Sang Z, Li Z, Liu F, Mao J, Yan D, Zhao Y, Wang H, Li P, Ying X, Zhang X, He K, Wang H
Scientific reports 2017 Apr 5;7:45913
Scientific reports 2017 Apr 5;7:45913
FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions.
Wu W, Lin C, Wu K, Jiang L, Wang X, Li W, Zhuang H, Zhang X, Chen H, Li S, Yang Y, Lu Y, Wang J, Zhu R, Zhang L, Sui S, Tan N, Zhao B, Zhang J, Li L, Feng D
The EMBO journal 2016 Jul 1;35(13):1368-84
The EMBO journal 2016 Jul 1;35(13):1368-84
Tumor-suppressive functions of long-chain acyl-CoA synthetase 4 in gastric cancer.
Ye X, Zhang Y, Wang X, Li Y, Gao Y
IUBMB life 2016 Apr;68(4):320-7
IUBMB life 2016 Apr;68(4):320-7
Quantitative proteomic analysis identifies new effectors of FOXM1 involved in breast cancer cell migration.
Ye X, Zhang Y, He B, Meng Y, Li Y, Gao Y
International journal of clinical and experimental pathology 2015;8(12):15836-44
International journal of clinical and experimental pathology 2015;8(12):15836-44
Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells.
Saka HA, Thompson JW, Chen YS, Dubois LG, Haas JT, Moseley A, Valdivia RH
PloS one 2015;10(4):e0124630
PloS one 2015;10(4):e0124630
Involvement of cholesterol in hepatitis B virus X protein-induced abnormal lipid metabolism of hepatoma cells via up-regulating miR-205-targeted ACSL4.
Cui M, Xiao Z, Sun B, Wang Y, Zheng M, Ye L, Zhang X
Biochemical and biophysical research communications 2014 Mar 14;445(3):651-5
Biochemical and biophysical research communications 2014 Mar 14;445(3):651-5
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 22401-1-AP( ACSL4 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACSL4/FACL4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ACSL4/FACL4. This antibody recognizes human antigen. The ACSL4/FACL4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
