ABIN1673432

antibody from antibodies-online

Targeting: PHB2 Bap37, BCAP37, p22, REA

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1673432

Provider

antibodies-online

Product name

anti-Prohibitin 2 (PHB2) (Middle Region) antibody

Antibody type

Polyclonal

Antigen

A synthetic peptide corresponding to a sequence in the middle region of human PHB2, identical to the related rat and mouse sequences.Immunogen affinity purified.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

Middle Region

Isotype

IgG

Vial size

100 μg

Storage

At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Prohibitins control cell proliferation and apoptosis by regulating OPA1-dependent cristae morphogenesis in mitochondria.

Merkwirth C, Dargazanli S, Tatsuta T, Geimer S, Löwer B, Wunderlich FT, von Kleist-Retzow JC, Waisman A, Westermann B, Langer T
Genes & development 2008 Feb 15;22(4):476-88

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Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland.

Mussi P, Liao L, Park SE, Ciana P, Maggi A, Katzenellenbogen BS, Xu J, O'Malley BW
Proceedings of the National Academy of Sciences of the United States of America 2006 Nov 7;103(45):16716-21

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An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens.

Montano MM, Ekena K, Delage-Mourroux R, Chang W, Martini P, Katzenellenbogen BS
Proceedings of the National Academy of Sciences of the United States of America 1999 Jun 8;96(12):6947-52