Explore
Validate
Learn
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AP08343PU-N - Provider product page
- Provider
- Acris Antibodies GmbH
- Proper citation
- Acris Antibodies GmbH Cat#AP08343PU-N, RRID:AB_1953884
- Product name
- anti Prohibitin-2 (C-term)
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein (partial), C-terminal.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 50 µl
Submitted references Identification of prohibitin and prohibiton as novel factors binding to the p53 induced gene 3 (PIG3) promoter (TGYCC)(15) motif.
Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development.
Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.
Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein.
A missense mutation in Caenorhabditis elegans prohibitin 2 confers an atypical multidrug resistance.
Guan X, Liu Z, Wang L, Johnson DG, Wei Q
Biochemical and biophysical research communications 2014 Jan 24;443(4):1239-44
Biochemical and biophysical research communications 2014 Jan 24;443(4):1239-44
Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development.
Supale S, Thorel F, Merkwirth C, Gjinovci A, Herrera PL, Scorrano L, Meda P, Langer T, Maechler P
Diabetes 2013 Oct;62(10):3488-99
Diabetes 2013 Oct;62(10):3488-99
Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.
Lucas CR, Cordero-Nieves HM, Erbe RS, McAlees JW, Bhatia S, Hodes RJ, Campbell KS, Sanders VM
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 15;190(2):723-36
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 15;190(2):723-36
Identification of the cellular prohibitin 1/prohibitin 2 heterodimer as an interaction partner of the C-terminal cytoplasmic domain of the HIV-1 glycoprotein.
Emerson V, Holtkotte D, Pfeiffer T, Wang IH, Schnölzer M, Kempf T, Bosch V
Journal of virology 2010 Feb;84(3):1355-65
Journal of virology 2010 Feb;84(3):1355-65
A missense mutation in Caenorhabditis elegans prohibitin 2 confers an atypical multidrug resistance.
Zubovych I, Doundoulakis T, Harran PG, Roth MG
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 17;103(42):15523-8
Proceedings of the National Academy of Sciences of the United States of America 2006 Oct 17;103(42):15523-8
No comments: Submit comment
Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- MCF-7 whole cell extract was resolved by electrophoresis, transferred to Nitrocellulose and probed with rabbit anti-BAP37 antibody. Proteins were visualized using a donkey anti-rabbit secondary conjugated to HRP and a chemiluminescence detection system.
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Immunofluorescent microscope analysis of Hela cells using anti-BAP37 antibody (red). Nuclei were stain with DAPI (blue).
Supportive validation
- Submitted by
- Acris Antibodies GmbH (provider)
- Main image
- Experimental details
- Brain, cortex: Formalin-Fixed Paraffin-Embedded (FFPE)
