66424-1-Ig

antibody from Proteintech Group

Targeting: PHB2 Bap37, BCAP37, p22, REA

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66424-1-Ig

Provider

Proteintech Group

Product name

Prohibitin 2 antibody

Antibody type

Monoclonal

Description

KD/KO validated Prohibitin 2 antibody (Cat. #66424-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1D9C7

Vial size

20ul, 150ul

References

Submitted references

CHCHD10(S59L/+) mouse model: Behavioral and neuropathological features of frontotemporal dementia.

Genin EC, di Borgo PP, Lorivel T, Hugues S, Farinelli M, Mauri-Crouzet A, Lespinasse F, Godin L, Paquis-Flucklinger V, Petit-Paitel A
Neurobiology of disease 2024 Jun 1;195:106498

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Rutin Attenuates Oxidative Stress Via PHB2-Mediated Mitophagy in MPP(+)-Induced SH-SY5Y Cells.

Lai X, Zhang Y, Wu J, Shen M, Yin S, Yan J
Neurotoxicity research 2023 Jun;41(3):242-255

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REC drives recombination to repair double-strand breaks in animal mtDNA.

Klucnika A, Mu P, Jezek J, McCormack M, Di Y, Bradshaw CR, Ma H
The Journal of cell biology 2023 Jan 2;222(1)

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Nonreceptor Tyrosine Kinase c-Abl-Mediated PHB2 Phosphorylation Aggravates Mitophagy Disorder in Parkinson's Disease Model.

Zhang Y, Wu J, Jin W, Shen M, Yin S, Lai X, Ma H, Jiang M, Sun D, Yan J
Oxidative medicine and cellular longevity 2022;2022:9233749

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Mechanical detection of interactions between proteins related to intermediate filament and transcriptional regulation in living cells.

Yamagishi A, Mizusawa M, Uchida K, Iijima M, Kuroda S, Fukazawa K, Ishihara K, Nakamura C
Biosensors & bioelectronics 2022 Nov 15;216:114603

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A549 cells contain enlarged mitochondria with independently functional clustered mtDNA nucleoids.

Nasonovs A, Garcia-Diaz M, Bogenhagen DF
PloS one 2021;16(3):e0249047

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Discovery of bactericides as an acute mitochondrial membrane damage inducer.

Houston R, Sekine Y, Larsen MB, Murakami K, Mullett SJ, Wendell SG, Narendra DP, Chen BB, Sekine S
Molecular biology of the cell 2021 Nov 1;32(21):ar32

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Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.

Le Vasseur M, Friedman J, Jost M, Xu J, Yamada J, Kampmann M, Horlbeck MA, Salemi MR, Phinney BS, Weissman JS, Nunnari J
eLife 2021 May 26;10

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Fluoride induced mitochondrial impairment and PINK1-mediated mitophagy in Leydig cells of mice: In vivo and in vitro studies.

Liang C, Gao Y, He Y, Han Y, Manthari RK, Tikka C, Chen C, Wang J, Zhang J
Environmental pollution (Barking, Essex : 1987) 2020 Jan;256:113438

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Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection.

Su W, Huang S, Zhu H, Zhang B, Wu X
Viruses 2020 Apr 8;12(4)

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Mitochondrial stress response triggered by defects in protein synthesis quality control.

Richter U, Ng KY, Suomi F, Marttinen P, Turunen T, Jackson C, Suomalainen A, Vihinen H, Jokitalo E, Nyman TA, Isokallio MA, Stewart JB, Mancini C, Brusco A, Seneca S, Lombès A, Taylor RW, Battersby BJ
Life science alliance 2019 Feb;2(1)

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NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy.

Furuya N, Kakuta S, Sumiyoshi K, Ando M, Nonaka R, Suzuki A, Kazuno S, Saiki S, Hattori N
EMBO reports 2018 Dec;19(12)