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- Antibody Data
- Antigen structure
- References [9]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 19912-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19912-1-AP, RRID:AB_10642438
- Product name
- C20orf149 antibody
- Antibody type
- Polyclonal
- Description
- C20orf149 antibody (Cat. #19912-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references PPDPF-mediated regulation of BCAA metabolism enhances mTORC1 activity and drives cholangiocarcinoma progression.
PPDPF preserves integrity of proximal tubule by modulating NMNAT activity in chronic kidney diseases.
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism.
Phosphorylation of PPDPF via IL6-JAK2 activates the Wnt/β-catenin pathway in colorectal cancer.
PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1.
PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell Lung Cancer.
The Exocrine Differentiation and Proliferation Factor (EXDPF) Gene Promotes Ovarian Cancer Tumorigenesis by Up-Regulating DNA Replication Pathway.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Pancreatic progenitor cell differentiation and proliferation factor predicts poor prognosis in heptaocellular carcinoma.
Li Z, Guan Y, Gao J, Zhu L, Zeng Z, Jing Q, Wan Q, Fan Q, Ren X, Pei H, Zhang D, Rong Y, Rong Z, He J, Zhang Y, Li N, Chen P, Sun L, Xu B, Nie Y, Deng Y
Oncogene 2025 May;44(19):1415-1433
Oncogene 2025 May;44(19):1415-1433
PPDPF preserves integrity of proximal tubule by modulating NMNAT activity in chronic kidney diseases.
Fang X, Zhong Y, Zheng R, Wu Q, Liu Y, Zhang D, Wang Y, Ding W, Wang K, Zhong F, Lin K, Yao X, Hu Q, Li X, Xu G, Liu N, Nie J, Li D, Geng H, Guan Y
Science advances 2025 Mar 21;11(12):eadr8648
Science advances 2025 Mar 21;11(12):eadr8648
PPDPF promotes esophageal squamous cell carcinoma progression by blocking PCCA binding to PCCB and inhibiting methionine catabolism.
Li M, Zhang Y, Wang Z, Wang K, Gao J, Gu H, Zeng Z, Jiang H, Fan Q, Zhang Y, Hu X, Cui L, Deng Y, Sun Y
Cancer letters 2024 Dec 16;611:217402
Cancer letters 2024 Dec 16;611:217402
Phosphorylation of PPDPF via IL6-JAK2 activates the Wnt/β-catenin pathway in colorectal cancer.
Zi Y, Liu L, Gao J, Xu X, Guan Y, Rong Z, Cao Z, Li M, Zeng Z, Fan Q, Tang F, He J, Feng D, Chen J, Dai Y, Huang Y, Nie Y, Pei H, Cai Q, Li Z, Sun L, Deng Y
EMBO reports 2023 Sep 6;24(9):e55060
EMBO reports 2023 Sep 6;24(9):e55060
PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1.
Wang YK, Ma N, Xu S, Huang JY, Ni QZ, Cao HJ, Zheng QW, Zhu B, Xia J, Zhang FK, Ding XF, Qiu XS, Chen TW, Wang K, Chen W, Li ZG, Cheng SQ, Xie D, Li JJ
Cell reports 2023 Apr 25;42(4):112340
Cell reports 2023 Apr 25;42(4):112340
PPDPF Promotes the Progression and acts as an Antiapoptotic Protein in Non-Small Cell Lung Cancer.
Yun M, Yingzi L, Jie G, Guanxin L, Zimei Z, Zhen C, Zhi L, Yingjie N, Lunquan S, Tao C, Yuezhen D, Chengzhi Z
International journal of biological sciences 2022;18(1):214-228
International journal of biological sciences 2022;18(1):214-228
The Exocrine Differentiation and Proliferation Factor (EXDPF) Gene Promotes Ovarian Cancer Tumorigenesis by Up-Regulating DNA Replication Pathway.
Xiao Y, Lai Y, Yu Y, Jiang P, Li Y, Wang C, Zhang R
Frontiers in oncology 2021;11:669603
Frontiers in oncology 2021;11:669603
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.
Morgenstern M, Peikert CD, Lübbert P, Suppanz I, Klemm C, Alka O, Steiert C, Naumenko N, Schendzielorz A, Melchionda L, Mühlhäuser WWD, Knapp B, Busch JD, Stiller SB, Dannenmaier S, Lindau C, Licheva M, Eickhorst C, Galbusera R, Zerbes RM, Ryan MT, Kraft C, Kozjak-Pavlovic V, Drepper F, Dennerlein S, Oeljeklaus S, Pfanner N, Wiedemann N, Warscheid B
Cell metabolism 2021 Dec 7;33(12):2464-2483.e18
Cell metabolism 2021 Dec 7;33(12):2464-2483.e18
Pancreatic progenitor cell differentiation and proliferation factor predicts poor prognosis in heptaocellular carcinoma.
Mao Z, Li X, Ma X, Wang X, Zhang J, Fan X
Medicine 2019 Mar;98(9):e14552
Medicine 2019 Mar;98(9):e14552
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 19912-1-AP(C20orf149 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using C20orf149 antibody 19912-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 19912-1-AP(C20orf149 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon using 19912-1-AP(C20orf149 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
