BS8089

antibody from Bioworld Technology, Inc
Targeting: DEK D6S231E
Provider product page for BS8089
Western blot
Immunohistochemistry

Antibody data

Product number
BS8089 - Provider product page
Provider
Bioworld Technology, Inc
Product name
DEK polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human DEK.
Description
The mammalian nuclear phosphoprotein DEK is implicated in multiple cellular processes, including transcriptional regulation, mRNA processing, and chromatin remodeling, and is associated with a number of clinical autoimmune and neoplastic conditions. DEK, an abundant chromatin-associated protein, changes the topology of DNA in chromatin in vitro. Although first identified in a fusion with the CAN/Nup214 nucleoporin protein in a specific subtype of acute myelogenous leukemia, DEK is also an autoantigen in patients with pauciarticular onset juvenile rheumatoid arthritis. Furthermore, the last 65 amino acids of DEK can partially reverse the mutation-prone phenotype of cells from patients with ataxia-telangiectasia. The human DEK gene maps to chromosome 6p23.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
DEK protein structure - BS8089 shown in red.