HPA023646

antibody from Atlas Antibodies

Targeting: PLPBP PROSC

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA023646

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA023646, RRID:AB_1855741

Product name

Anti-PROSC

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human PROSC, Gene description: proline synthetase co-transcribed homolog (bacterial), Validated applications: WB, IHC, Uniprot ID: O94903, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.05 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Maintenance of cellular vitamin B6 levels and mitochondrial oxidative function depend on pyridoxal 5′-phosphate homeostasis protein

Ciapaite J, van Roermund C, Bosma M, Gerrits J, Houten S, IJlst L, Waterham H, van Karnebeek C, Wanders R, Zwartkruis F, Jans J, Verhoeven-Duif N
Journal of Biological Chemistry 2023;299(9):105047

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A founder mutation in the PLPBP gene in families from Saguenay‐Lac‐St‐Jean region affected by a pyridoxine‐dependent epilepsy

Pal M, Lace B, Labrie Y, Laflamme N, Rioux N, Setty S, Dugas M, Gosselin L, Droit A, Chrestian N, Rivest S
JIMD Reports 2021;59(1):32-41

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Mutations in PROSC Disrupt Cellular Pyridoxal Phosphate Homeostasis and Cause Vitamin-B6-Dependent Epilepsy

Darin N, Reid E, Prunetti L, Samuelsson L, Husain R, Wilson M, El Yacoubi B, Footitt E, Chong W, Wilson L, Prunty H, Pope S, Heales S, Lascelles K, Champion M, Wassmer E, Veggiotti P, de Crécy-Lagard V, Mills P, Clayton P
The American Journal of Human Genetics 2016;99(6):1325-1337