Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 13023-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13023-1-AP, RRID:AB_2180064
- Product name
- RRAGB antibody
- Antibody type
- Polyclonal
- Description
- RRAGB antibody (Cat. #13023-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tissue-specific expression differences in Ras-related GTP-binding proteins in male rats.
RRAGB-mediated suppression of PI3K/AKT exerts anti-cancer role in glioblastoma.
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop.
YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.
Ursolic acid inhibits leucine-stimulated mTORC1 signaling by suppressing mTOR localization to lysosome.
Kincheloe GN, Roberson PA, Jefferson LS, Kimball SR
Physiological reports 2024 Feb;12(3):e15928
Physiological reports 2024 Feb;12(3):e15928
RRAGB-mediated suppression of PI3K/AKT exerts anti-cancer role in glioblastoma.
Li Q, Liu X, Mao J, Liu S, Hou B, Li K, Fang D
Biochemical and biophysical research communications 2023 Oct 8;676:149-157
Biochemical and biophysical research communications 2023 Oct 8;676:149-157
Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.
Li MX, Wu XT, Jing WQ, Hou WK, Hu S, Yan W
Cell death & disease 2023 Aug 2;14(8):492
Cell death & disease 2023 Aug 2;14(8):492
circEXOC6B interacting with RRAGB, an mTORC1 activator, inhibits the progression of colorectal cancer by antagonizing the HIF1A-RRAGB-mTORC1 positive feedback loop.
Li X, Wang J, Lin W, Yuan Q, Lu Y, Wang H, Chen Y, Chen L, Dai P, Long H, Li X
Molecular cancer 2022 Jun 23;21(1):135
Molecular cancer 2022 Jun 23;21(1):135
YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.
Ikeda S, Nah J, Shirakabe A, Zhai P, Oka SI, Sciarretta S, Guan KL, Shimokawa H, Sadoshima J
The Journal of clinical investigation 2021 Mar 1;131(5)
The Journal of clinical investigation 2021 Mar 1;131(5)
Ursolic acid inhibits leucine-stimulated mTORC1 signaling by suppressing mTOR localization to lysosome.
Ou X, Liu M, Luo H, Dong LQ, Liu F
PloS one 2014;9(4):e95393
PloS one 2014;9(4):e95393
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 13023-1-AP(RRAGB antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RRAGB antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RRAGB. This antibody recognizes human,mouse,rat antigen. The RRAGB antibody has been validated for the following applications: ELISA, WB, IHC analysis.