Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13561-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13561-1-AP, RRID:AB_2124968
- Product name
- IKZF3 antibody
- Antibody type
- Polyclonal
- Description
- IKZF3 antibody (Cat. #13561-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Lys-63-specific deubiquitinase BRCC36 enhances the sensitivity of multiple myeloma cells to lenalidomide by inhibiting lysosomal degradation of cereblon.
Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.
Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma.
Wang B, Li M, Cao D, Sun Q, Yu W, Ma J, Ren H, Xu G, Zhou L
Cellular and molecular life sciences : CMLS 2024 Aug 13;81(1):349
Cellular and molecular life sciences : CMLS 2024 Aug 13;81(1):349
Caspase-8 Inhibition Prevents the Cleavage and Degradation of E3 Ligase Substrate Receptor Cereblon and Potentiates Its Biological Function.
Zhou L, Yu W, Jayabalan DS, Niesvizky R, Jaffrey SR, Huang X, Xu G
Frontiers in cell and developmental biology 2020;8:605989
Frontiers in cell and developmental biology 2020;8:605989
Expression of CRBN, IKZF1, and IKZF3 does not predict lenalidomide sensitivity and mutations in the cereblon pathway are infrequent in multiple myeloma.
Dimopoulos K, Fibiger Munch-Petersen H, Winther Eskelund C, Dissing Sjö L, Ralfkiaer E, Gimsing P, Grønbaek K
Leukemia & lymphoma 2019 Jan;60(1):180-188
Leukemia & lymphoma 2019 Jan;60(1):180-188
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The IKZF3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IKZF3. This antibody recognizes human, mouse, rat antigen. The IKZF3 antibody has been validated for the following applications: ELISA, WB analysis.