Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 19055-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#19055-1-AP, RRID:AB_10643381
- Product name
- IKZF3 antibody
- Antibody type
- Polyclonal
- Description
- IKZF3 antibody (Cat. #19055-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification and Functional Analysis of a de novo IKZF3 Mutation in a Pediatric Patient with Combined Immunodeficiency.
Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy.
IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform.
Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells.
Shi X, Cao X, Huang M, Zhang P, Yang G, Ren A, Dai X, Chen R, Yang Z, Cai Z, Chen Y, Zhao X, Huang P, Du Z
Journal of clinical immunology 2024 May 17;44(5):117
Journal of clinical immunology 2024 May 17;44(5):117
Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy.
Chen S, Chen Z, Lu L, Zhao Y, Zhou R, Xie Q, Shu Y, Lin J, Yu X, Wang Y
European journal of medicinal chemistry 2023 Jul 5;255:115403
European journal of medicinal chemistry 2023 Jul 5;255:115403
IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform.
Harama D, Yahata T, Kagami K, Abe M, Ando N, Kasai S, Tamai M, Akahane K, Inukai T, Kiyokawa N, Ibrahim AA, Ando K, Sugita K
Cell death discovery 2021 Jun 11;7(1):139
Cell death discovery 2021 Jun 11;7(1):139
Overexpression of Aiolos promotes epithelial-mesenchymal transition and cancer stem cell-like properties in lung cancer cells.
Hung JJ, Kao YS, Huang CH, Hsu WH
Scientific reports 2019 Feb 28;9(1):2991
Scientific reports 2019 Feb 28;9(1):2991
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 19055-1-AP(IKZF3 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using IKZF3 antibody 19055-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human spleen using 19055-1-AP(IKZF3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human spleen using 19055-1-AP(IKZF3 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue