15914-1-AP

antibody from Proteintech Group

Targeting: CTPS1 CTPS, GATD5

Provider product page for 15914-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Flow cytometry

Antibody data

Antibody Data
Antigen structure
References [21]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

Submit

Product number: 15914-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#15914-1-AP, RRID:AB_2086513
Product name: CTP synthase antibody
Antibody type: Polyclonal
Description: CTP synthase antibody (Cat. #15914-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CTPS1 protein structure - 15914-1-AP shown in red.

Submitted references HIF-1α mediates osteoclast-induced disuse osteoporosis via cytoophidia in the femur of mice.

Bie M, Tang Y, Xia Y, Zhang Q, Tian Y, Cheng C, Li X, Qi X, Kang F
Bone 2023 Mar;168:116648

MYC-induced cytidine metabolism regulates survival and drug resistance via cGas-STING pathway in mantle cell lymphoma.

Liang JH, Ren YM, Du KX, Gao R, Duan ZW, Guo JR, Xing TY, Wang WT, Wang L, Wang Y, Wang R, Li JY, Xu W
British journal of haematology 2023 Aug;202(3):550-565

Super-Resolution Imaging Reveals Dynamic Reticular Cytoophidia.

Fang YF, Li YL, Li XM, Liu JL
International journal of molecular sciences 2022 Oct 2;23(19)

Combined Inactivation of CTPS1 and ATR Is Synthetically Lethal to MYC-Overexpressing Cancer Cells.

Sun Z, Zhang Z, Wang QQ, Liu JL
Cancer research 2022 Mar 15;82(6):1013-1024

Molecular crowding facilitates bundling of IMPDH polymers and cytoophidium formation.

Chang CC, Peng M, Zhong J, Zhang Z, Keppeke GD, Sung LY, Liu JL
Cellular and molecular life sciences : CMLS 2022 Jul 14;79(8):420

Gm14230 controls Tbc1d24 cytoophidia and neuronal cellular juvenescence.

Morimune T, Tano A, Tanaka Y, Yukiue H, Yamamoto T, Tooyama I, Maruo Y, Nishimura M, Mori M
PloS one 2021;16(4):e0248517

Energy deficiency caused by CTPS downregulation in decidua may contribute to pre-eclampsia by impairing decidualization.

Ma K, Li N, Yan X, Zhu Y, Zhang C
Journal of cellular physiology 2021 Sep;236(9):6520-6533

Species-Specific Deamidation of RIG-I Reveals Collaborative Action between Viral and Cellular Deamidases in HSV-1 Lytic Replication.

Huang H, Zhao J, Wang TY, Zhang S, Zhou Y, Rao Y, Qin C, Liu Y, Chen Y, Xia Z, Feng P
mBio 2021 Mar 30;12(2)

Targeting CTP Synthetase 1 to Restore Interferon Induction and Impede Nucleotide Synthesis in SARS-CoV-2 Infection.

Rao Y, Wang TY, Qin C, Espinosa B, Liu Q, Ekanayake A, Zhao J, Savas AC, Zhang S, Zarinfar M, Liu Y, Zhu W, Graham N, Jiang T, Zhang C, Feng P
bioRxiv : the preprint server for biology 2021 Feb 7;

CTPS forms the cytoophidium in zebrafish.

Chang CC, Keppeke GD, Antos CL, Peng M, Andrade LEC, Sung LY, Liu JL
Experimental cell research 2021 Aug 15;405(2):112684

CTPS and IMPDH form cytoophidia in developmental thymocytes.

Peng M, Chang CC, Liu JL, Sung LY
Experimental cell research 2021 Aug 1;405(1):112662

Flow Cytometry Contributions for the Diagnosis and Immunopathological Characterization of Primary Immunodeficiency Diseases With Immune Dysregulation.

Cabral-Marques O, Schimke LF, de Oliveira EB Jr, El Khawanky N, Ramos RN, Al-Ramadi BK, Segundo GRS, Ochs HD, Condino-Neto A
Frontiers in immunology 2019;10:2742

Blood feeding activates the vitellogenic stage of oogenesis in the mosquito Aedes aegypti through inhibition of glycogen synthase kinase 3 by the insulin and TOR pathways.

Valzania L, Mattee MT, Strand MR, Brown MR
Developmental biology 2019 Oct 1;454(1):85-95

mTOR-S6K1 pathway mediates cytoophidium assembly.

Sun Z, Liu JL
Journal of genetics and genomics = Yi chuan xue bao 2019 Feb;46(2):65-74

Compositional complexity of rods and rings.

Schiavon CR, Griffin ME, Pirozzi M, Parashuraman R, Zhou W, Jinnah HA, Reines D, Kahn RA
Molecular biology of the cell 2018 Sep 15;29(19):2303-2316

Interfilament interaction between IMPDH and CTPS cytoophidia.

Chang CC, Keppeke GD, Sung LY, Liu JL
The FEBS journal 2018 Oct;285(20):3753-3768

CTP synthase forms the cytoophidium in human hepatocellular carcinoma.

Chang CC, Jeng YM, Peng M, Keppeke GD, Sung LY, Liu JL
Experimental cell research 2017 Dec 15;361(2):292-299

Differential capacity of therapeutic drugs to induce Rods/Rings structures in vitro and in vivo and generation of anti-Rods/Rings autoantibodies.

Keppeke GD, Prado MS, Nunes E, Perazzio SF, Rodrigues SH, Ferraz ML, Chan EK, Andrade LE
Clinical immunology (Orlando, Fla.) 2016 Dec;173:149-156

Identification and validation of differentially expressed proteins in epithelial ovarian cancers using quantitative proteomics.

Qu H, Chen Y, Cao G, Liu C, Xu J, Deng H, Zhang Z
Oncotarget 2016 Dec 13;7(50):83187-83199

'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway.

Calise SJ, Purich DL, Nguyen T, Saleem DA, Krueger C, Yin JD, Chan EK
Journal of cell science 2016 Aug 1;129(15):3042-52

Assembly of IMPDH2-based, CTPS-based, and mixed rod/ring structures is dependent on cell type and conditions of induction.

Keppeke GD, Calise SJ, Chan EK, Andrade LE
Journal of genetics and genomics = Yi chuan xue bao 2015 Jun 20;42(6):287-99

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 15914-1-AP(CTPS antibody) at dilution of 1:500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using CTPS antibody 15914-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line